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GENERAL BIOLOGY 1
K.C.L.M
EVOLUTION
o (November 24, 1859) – published a detailed explanation of his theory in On the Origin of Species
by Means of Natural Selection
o (next century) – DNA studies gave scientific evidence for the theory; but it was in conflict with
Creationism (religious view that everything was created by God)
Social Darwinism – collection of ideas in the late 1800s that used Darwin’s theory of evolution to highlight
and expound social and economic issues
o Darwin rarely established a connection between his theories and human society but to explain his
views, he used widely understood concepts such as survival of the fittest from Herbert Spencer
(sociologist)
o (during the Industrial Revolution and laissez faire capitalism) Social Darwinism was used as
justification for imperialism, labor abuses, racism, poverty, eugenics, social inequality
Died at his family home (Down House, London); buried at Westminster Abbey
(more than a century after) Richard Brum (Yale ornithologist) tried to revive Darwin’s theory on sexual
selection in The Evolution of Beauty
o Darwin: female aesthetic mating choices became the driving force of evolution
o Brum: had an effective argument through birds’ expertise (The New York Times’ list of 10 best
books of 2017)
REFERENCE:
Biography.com. (2014, April 2). Charles Darwin Biography. Retrieved from The Biography:
https://www.biography.com/scientist/charles-darwin
2Charles Darwin (BBC, n.d.)
Grandfathers: Erasmus Darwin (doctor, Zoonomia: species could transmute into another); Josiah
Wedgewood (industrialist and anti-slavery campaigner)
(1838) Darwin’s explanation of transmutation: animals well-adapted to the environment survive longer and
reproduced. Evolution happened through Natural Selection.
(Summer 1858) Alfred Russel Wallace (admirer of Darwin) set off to travel after his inspiration of the Beagle
Voyage. He wants to arrive at a theory of Natural Selection to publish. Darwin was afraid that Wallace will
take credit.
(July 1858) publicizing the theory to the Linnean Society – Britain’s leading Natural History body. The
presentation included Darwin’s and Wallace’s work.
(November 1859) Publishing of On the Origin of Species by Means of Natural Selection
(June 1860) Darwin’s Theory of Evolution on trial at Oxford University. Thomas Huxley defended the ideas
in public. He went head to head with Bishop Samuel Wilberforce
o Both sides were victors and it was Darwin Legend that shook the Victorian Society
(February 1871) The Descent of Man – unequivocal account of human evolution (a challenge to Christian
orthodoxy). His ideas were accepted eventually
REFERENCE:
BBC. (n.d.). Charles Darwin: Evolution and the story of our species. Retrieved from BBC - iWonder:
https://www.bbc.com/timelines/zq8gcdm
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
Aims:
To analyze the limits of variation within created species
To use the limits of variation to define species in a practice referred to as collation (he was
conforming that species don’t evolve but only have the capacity to vary within limits)
o Darwin and Henslow had the friendship that influenced the former’s career. Darwin took Henslow’s
5-week botany course three times (1829-1831) The man who walks with Henslow
Adam Sedgwick (1785-1873)
o (1818) ordained as Anglican clergyman before being a professor of Geology
(Chair of Geology)
o Catastrophist
o Believed in a succession of Divine creative acts throughout the long expanse
of history / long geological ages
o Totally opposed to all theories of biological evolution
o Origin of Species in 1859: more pain than pleasure because it is very opposite
to the inductive truth
REFERENCE:
Grigg, R. (2010, January). Darwin's mentors. Retrieved from Creation.com: https://creation.com/clergy-mentor-
darwin
o His view: the difference of humans from all other life forms is reason and the highest application of
reason is science. Natural selection was science at its best but the downside of it was making
humans fundamentally the same as the other forms of life
REFERENCE:
Charles Lyell. (n.d.). Retrieved from University of Cambridge: Darwin Correspondence Project:
https://www.darwinproject.ac.uk/charles-lyell
(McNamara, 2019)
Impression on Sydney
Coral reefs
o Cape of Good Hope, South Africa (May 1836) – Atlantic Ocean – St. Helena – British Outpost,
Ascension Island, South Atlantic – South America – Falmouth, England (October 2, 1836)
REFERENCE:
McNamara, R. (2019, June 4). Charles Darwin and His Voyage Aboard H.M.S. Beagle. Retrieved from
ThoughtCo.: https://www.thoughtco.com/charles-darwin-and-his-voyage-1773836
REFERENCE:
Charles Darwin: Time Line. (1996, September). Retrieved from Bertie.ccsu.edu:
https://bertie.ccsu.edu/darwinevol/DarwinTimeLine.html
Mechanisms of Evolution
1. Descent with Modification – new organism descends from the previous organism but is genetically
modified; therefore, the change in the gene frequency within the population will occur in a period of time =
these traits are heritable and are passed to the next generations (Evolution 101, n.d.)
2. Basic Mechanism of Change
a. *Adaptation: any characteristic that increases fitness, which is equivalent to survival and
reproduction (Morano, Lopez, & Tan, 2011)
b. *Natural Selection: differential success in the reproduction of phenotypes resulting from the
interaction of organisms and the environment. The fittest survive and contribute their genes to
offspring; thus, creating a population (Morano, Lopez, & Tan, 2011). Three types:
i. Stabilizing selection – environment continually eliminates individuals at extremes of a
population
ii. Disruptive selection – environment splits population into two or more populations due to
favoring the extreme types in a population at the expense of intermediate forms
iii. Directional selection – environment acts for or against an extreme characteristic, resulting
to a replacement of one gene group with another gene group (e.g. antibiotic-resistant
bacteria)
c. Artificial Selection: farmers and breeders (people) are the ones in control of reproduction of organisms,
not nature. They engineer or match organisms with desirable characteristics to reproduce, leading also
to evolution (new species/organisms) (Evolution 101, n.d.)
d. *Genetic Drift: when a small group of organisms leaves a population and moves into a new area that
is geographically isolated region (Morano, Lopez, & Tan, 2011)
3. Genetic Variation – variation in DNA sequence and genome
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
a. *Mutation: driving force of evolution and is a rare/random change in the population’s gene pool,
creating an ultimate genetic diversity. Source of variation in a population. Can be harmful or
beneficial (Morano, Lopez, & Tan, 2011)
b. *Gene Flow: may occur during the migration of individuals from one group to another. They
contribute their genes to the genes of the local population. It may refer to loss or gain of alleles in
a population due to migration. Gene flow may also increase the similarities between remaining
populations of the same species (Morano, Lopez, & Tan, 2011)
c. Sex: production of offspring, transfer and combination of DNA to form a unique organism.
Changes/evolves over time, space, ability to adapt to the environment, number within population
(Otto, 2008). Can also introduce new gene combinations to a population/genetic shuffling (Evolution
101, n.d.)
d. Recombination: formation and combination of new genes during meiosis that cannot be done in
natural selection (because in natural selection, it only makes use of the existing genetic variations)
(O'Neil, n.d.)
4. Genetic Drift – per generation, some individuals may leave (by chance) a few descendants together with
their genes MORE than the other individuals. Those who were left may still contribute to the genes of the
next generation, thus, the next generation will carry the genes of the “lucky” individuals (left descendants);
however, it doesn’t mean that its healthier or better. HAPPENS TO ALL POPULATIONS (Evolution 101,
n.d.)
5. Coevolution – as one species change, the other species must also change in order to adapt. Simply, it
occurs when species EVOLVE together. This is most common in species with symbiotic relationships:
(Wilkin & Brainard, Coevolution, 2012)
a. Predator/prey
b. Parasite/host
c. Competitive species
d. Mutualistic species
REFERENCES:
Evolution 101. (n.d.). Retrieved from Understanding Evolution:
https://evolution.berkeley.edu/evolibrary/article/evo_24
Morano, L. N., Lopez, C. S., & Tan, A. S. (2011). Fundamentals of Biology I. Quezon City: Lorimar Publishing Inc.
Otto, S. P. (2008). Sexual Reproduction and Evolution of Sex. Retrieved from Scitable by Nature Education:
https://www.nature.com/scitable/topicpage/sexual-reproduction-and-the-evolution-of-sex-824
Wilkin, D., & Brainard, J. (2012, February 25). Coevolution. Retrieved from cK-12:
https://www.ck12.org/biology/coevolution/lesson/Coevolution-BIO/
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
comparisons of the embryos of animals – most common for vertebrates (fish, amphibians, reptiles, birds, mammals)
because they follow the same pattern.
Development of notochord (core of the intervertebral disks)
Somites (will become bone, muscle, skin)
Series of arches below the head / gill arches / pharyngeal arches
3. Comparative biochemistry for examining similarities between molecules – make use of proteins and
genes to determine relationships among species. If two species are identical or nearly identical in
biochemical molecules, it can be inferred that they are from a common ancestry (homologous molecules).
Sometimes, they are from diverging evolutionary paths where one species becomes two different species.
a. Mutations. If it occurs over long periods of time, it may gradually modify the original molecule into
two new species. The greater the difference between two molecules of the same function in two
species, the earlier are these two species diverged from a common ancestor.
i. Cytochrome c (important protein in the metabolic pathways for energy exchange) is found
in yeasts to humans.
1. In humans = 104 amino acids
2. In chimpanzees = identical to humans
3. In human and chimpanzees = 1 amino acid different from rhesus monkeys
a. THEREFORE, HUMANS ARE MORE CLOSELY RELATED TO
CHIMPANZEES THAN TO RHESUS MONKEYS AND THAT HUMANS
ARE ALSO MORE RELATED TO OTHER PRIMATES THAN CHICKEN
OR YEASTS
4. Biogeography – study of the distribution of plants and animals around the world. This answers the question,
why do we see plants and animals only in some parts of the world? MIGRATION, BLOCKERS, and
CONTINENTAL DRIFT.
a. Migration. If an organism’s ability to migrate is inhibited if it lives in an isolated region such as an
island or where there are geographic barriers. If this is possible, it often occurs that closely related
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
organisms evolve first in one location and then spread to regions that are accessible to and can
benefit them.
b. Blockers. These comprises physical barriers, environments wherein they threaten survival of the
organism. If organisms are able to overcome or has already dispersed/migrated and have adjusted
to the new conditions of the location, then we can see the essence of geography on evolution and
distribution of life forms.
c. Continental Drift. Plates slowly moved over time and by this, some related organisms were
isolated from each other and have evolved separately but still following parallel paths. There are
still similarities.
Natural Selection Contributes to Evolution – DNA contains all the codes for an organism’s life processes and if
all organisms have the same set of DNA, they will all be 100% identical in both form and function. However,
differences in DNA result to differences among species and even among individuals belonging to a species.
Random mutations underlie evolution
o Gene pool changes gradually in respect to time due to mutations occurring in the genes of individual
members of the said species
o Mutations are rare accidental events that produces a different form of a gene: allele.
o Mutations can be: neutral, detrimental, beneficial
o Accumulating mutations may cause changes to physical and functional traits
o “ may cause divergence of species into two
o WITHOUT MUTATIONS, THERE WILL BE NO EVOLUTION
Natural selection encourages changes in the gene pool
o Mutations alone cannot take over evolution. There will always be a contribution from natural
selection
o Organisms interact with their home environment = varying life span
o Allele frequency in a gene pool of species DEPENDS on the survival rate of that allele
o Natural selection means that INDIVIDUALS WHO HAVE MORE ADAPTIVE AND RESPONSIVE
TRAITS ARE FITTER TO LIVE IN THEIR PRESENT ENVIRONMENT THAN THOSE WITHOUT
THESE SAID TRAITS. THE LATTER WILL HAVE LESS CHANCE TO SURVIVE AND
REPRODUCE.
o Mutation + natural selection = certain genes to increase and others to decrease within a gene pool
of a population
Genetic drift and gene flow alter populations
o Population – group of individuals of the same species that live in the same geographical area
o Not only natural selection affects evolution: genetic drift, gene flow, selective hunting
Genetic Drift. Random changes in allele frequency because of chance events. Usually
occurs in small populations because they are more susceptible to change.
Bottleneck effect – occurs when a major catastrophe strikes a population and
wipes it out regardless of fitness.
Founder effect – occurs when a few individuals leave the original group and begin
a new population in a different area. In both cases, the few genes left in the gene
pool cannot be considered as a representative of the original population nor the
most fit genes.
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
Gene Flow. Geographical redistribution of alleles that tends to mix gene pools or might not
mix. Movement of organisms may be immigration (into) and out of (emigration) the
population.
Antigenic shift – rapid change in a virus where it results to different combination
of genes resulting to more danger.
Mass extinctions eliminated many species
o Extinction – when a life form dies out completely
o Permian-Triassic: largest mass extinction
Evolutionary trees trace relationships between species
o Evolutionary tree (phylogenic tree) – illustration of the evolutionary change and relationships among
species.
Branches – point of divergence between two species
Length of the branches – time
Adaptive radiation – numerous branches from a single point on the tree
REFERENCE:
Johnson, M. D. (2017). Human Biology: Concepts and Current Issues. Essex: Pearson Education Limited .
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
Mockingbirds - comparison of 2
mockingbirds from the G.I, 1
from San Cristobal, 1 from
Floreana
- hint that species might evolve
over time
Rhea - in Patagonia
- eating it at the time
Salvage the head, neck, wings,
some feathers
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
Pigeon - 1850s
- selective breeding over
successive generations
- process was analogous to
evolution through natural
selection
Fossils
BBC. (n.d.). Charles Darwin: Evolution and the story of our species. Retrieved from BBC - iWonder:
https://www.bbc.com/timelines/zq8gcdm
Biography.com. (2014, April 2). Charles Darwin Biography. Retrieved from The Biography:
https://www.biography.com/scientist/charles-darwin
Brain, M. (2001, July 25). How Evolution Works. Retrieved from HowStuffWorks:
https://science.howstuffworks.com/life/evolution/evolution1.htm
Charles Lyell. (n.d.). Retrieved from University of Cambridge: Darwin Correspondence Project:
https://www.darwinproject.ac.uk/charles-lyell
Johnson, M. D. (2017). Human Biology: Concepts and Current Issues. Essex: Pearson Education Limited .
McNamara, R. (2019, June 4). Charles Darwin and His Voyage Aboard H.M.S. Beagle. Retrieved from
ThoughtCo.: https://www.thoughtco.com/charles-darwin-and-his-voyage-1773836
Morano, L. N., Lopez, C. S., & Tan, A. S. (2011). Fundamentals of Biology I. Quezon City: Lorimar Publishing Inc.
Otto, S. P. (2008). Sexual Reproduction and Evolution of Sex. Retrieved from Scitable by Nature Education:
https://www.nature.com/scitable/topicpage/sexual-reproduction-and-the-evolution-of-sex-824
Than, K. (2018, February 26). What is Darwin's Theory of Evolution. Retrieved from Live Science:
https://www.livescience.com/474-controversy-evolution-works.html
Wilkin, D., & Brainard, J. (2012, February 25). Coevolution. Retrieved from cK-12:
https://www.ck12.org/biology/coevolution/lesson/Coevolution-BIO/
Wilkin, D., & Brainard, J. (2012, February 25). Darwin. Retrieved from cK-12:
https://www.ck12.org/biology/darwin/lesson/Darwins-Voyage-of-the-Beagle-BIO/
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
ECOLOGY
aka bioecology, bionomics, environmental biology
study of the relationships between organisms and their environment
(EVERYTHING YOU SEE AROUND YOU AND HOW YOU INTERACT WITH
THEM)
coined by Ernst Haeckel (German zoologist) oekologie (relation of the animal
both to its organic as well as its inorganic environment)
came from the Greek word oikos meaning “household”, “home”, “place to live”
ecology deals with the organism and its environment
of how it becomes a home
Ecosystem
the complex relationship between living and nonliving things
foundation of the Biosphere and the foundation of natural balance because it is
where the basic interactions between every organism take place
in an ecosystem, each organism inside has its own role, therefore, if any alien
enters, it is considered as a threat, because it has the tendency to disrupt the
balance existing in the ecosystem.
Aliens: natural to man-made calamities
Components of the Ecosystem
2 major divisions: ABIOTIC COMPONENTS AND BIOTIC COMPONENTS
Abiotic Components
o Nonliving things
o Minerals, climate, soil, water, sunlight
Biotic Components
o Living things
o You, animals, plants, etc.
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
All these components enable energy to flow in the ecosystem as well as the
nutrients
Sun’s energy is the primary source of energy in all of the ecosystems because
it is readily available and there is no need for human intervention to happen to
produce this
Autotrophs (self-sustaining organisms) absorb this energy and undergo
photosynthesis where the energy from the sun is used to convert CARBON
DIOXIDE and WATER into simple carbohydrates.
These carbohydrates are storages for energy for the production of organic
components such as lipids, proteins and starches for the survival of the
organism
Autotrophs = producers
the organic compounds produced by the autotrophs are needed for the survival
of the heterotrophs = consumers (incapable of producing their own food)
Types of Ecosystems
3 types of ecosystem = biomes
aquatic biomes – in water bodies (oceans, rivers, seas, lakes, springs)
o pond ecosystem: smaller and for mostly amphibians and insects,
sometimes, fishes
o river ecosystem: fishes, plants, amphibians, insects, and birds that hunt
for small fishes
o shallow water ecosystem: tiny fishes and corals close to land
o deep water ecosystem: gigantic sea creatures
Terrestrial Biomes – on land (forests, deserts, grasslands, tundras, coastal
regions)
o Rainforests: extremely dense because of a variety of small organisms in
tiny areas
o Tundra: relatively simple since few life forms can survive in here
o Deserts: opposite of tundra, but have extreme conditions. Animals would
prefer heat than cold.
o Forests: most abundant since it can support a lot of life forms
UNIVERSITY OF SANTO TOMAS
GENERAL BIOLOGY 1
K.C.L.M
Lentic Biomes – support both aquatic and terrestrial life forms (swamps,
mangroves?). photosynthesis is the only requirement
Trophic Levels, Food Chain, and Food Web
Trophic Level – nutritive levels in a food chain. Feeding patterns categorize the
organisms in trophic levels
FOOD CHAIN:
Producers are at the lowest level of the chain
Consumers of the producers are at the second level (herbivore or carnivore or
omnivore)
Carnivores that eat herbivores and carnivores that eat carnivores make up for
the third level, as well as omnivores
Quaternary consumers are those who ate these carnivores or omnivores
Decomposers make up for a different or topmost level because they help in
breaking down the waste materials and turn them back into nutrients for the
producers to use again.
APEX CONSUMERS: THE TOPMOST ORGANISMS IN A FOOD CHAIN
FOOD WEB: the interlinking of feeding relationships of various communities of
organisms