INSTRUMENTS

·· DNA Flow Technology

·· Reverse dot blot hybridization
·· Supported by hybriSoft (advanced management software)
·· Reagents supplied ready to use
·· Engineered and manufactured by Vitro S.A.

MOLECULAR DIAGNOSTIC KITS

BASED ON MULTIPLEX PCR
·· Fully automated AND MACROARRAY CHIP
·· 1-24 samples per run

DNA
·· 30-120 min.
·· UV light for DNA decontamination
·· Bar-code identification (reagents, samples)

FLOW
TECHNOLOGY

·· Semi-automated
·· 1-12 samples per run
·· 25-45 min.

Molecular diagnostic kits Distributed by

developed and manufactured by

Parque Tecnológico Ciencias de la Salud

Avda. del Conocimiento, 100.
18016 Granada (Spain)
Telf: (+34) 958 27 14 49
Fax: (+34) 958 27 14 34
Hotline: (+34) 958 10 50 11
export@vitro.bio
www.masterdiagnostica.com
 HPV DIRECT FLOW CHIP
·· Simultaneous detection and genotyping of
36 HPV genotypes

- High-risk genotypes: 16, 18, 26, 31, 33, 35, 39, 45, 51,
52, 53, 56, 58, 59, 66, 68, 73, and 82 SEPSIS FLOW CHIP
- Low-risk genotypes: 6, 11, 40, 42, 43, 44, 54, 55, 61, ··Simultaneous detection of more than 40 pathogens and
62, 67, 69, 70, 71, 72, 81, 84, and 89 20 antibiotic resistant genes responsible for sepsis,
including Gram + bacteria, Gram - bacteria, Fungi, and
·· No DNA extraction / purification antibiotic resistant determinants: MRSA, mecA, vanA,
·· L1 (GP5-GP6) consensus region vanB, ESBL and carbapenemases
·· Compatible with liquid-based cytologies, cytological
swabs and paraffin-embedded samples ·· Validated with External Quality Control Program for
·· Uracil-DNA Glycosylase to avoid contamination with PCR Molecular Diagnostics QCMD
products
·· Validated with WHO HPV Labnet Proficiency Panel SPNEU: Streptococcus pneumoniae; SMALTO: Stenotrophomonas maltophilia;
CAND: Candida spp.; ABAU: Acinetobacter baumannii; SMAR/KLEB: Serratia
marcescens/Klebsiella pneumonia; SAGAL: Streptococcus agalactiae;
B: Hybridization control; C: DNA quality control (Human beta-globin gene); STAPHYL: Staphylococcus spp.; SA: Staphylococcus aureus; ECOLI:
U: Universal control (L1 consensus probe); Numbers: Indicate the HPV genotype. Escherichia coli; ENTEROB: Enterobacter spp.; CALB: Candida albicans; LIS:
Listeria monocytogenes; ENTEROC: Enterococcus spp.; PAER: Pseudomonas
aeruginosa; KLEB: Klebsiella pneumoniae; STREP: Streptococcus spp.; NEISS:
Neisseria meningitidis; PROT/MOR: Proteus spp.; mecA: Methicillin resistence gene;
vanA: Vancomycin resistence gene; vanB: Vancomycin resistence gene; kpc: Class A
carbapenemase; sme: Class A carbapenemase; nmc/imi: Class A carbapenemase;
blaSHV: extended-spectrum β -lactamase SHV; blaCTX-M: extended-spectrum β-lactamase
CTX-M; ges: Class A carbapenemase; vim: Class B carbapenemase;gim: Class B carbapenemase;
BACTERIAL CNS FLOW CHIP smp: Class B carbapenemase; ndm: Class B carbapenemase; sim: Class B carbapenemase;
imp3: Class B carbapenemase; Imp15: Class B carbapenemase; Imp19: Class B carbapenemase;
·· Simultaneous detection of bacteria and fungus causing oxa 23: Class D carbapenemase; oxa 24: Class D carbapenemase; oxa 48: Class D carbapenemase;
CNS infections oxa 51: Class D carbapenemase; oxa 58: Class D carbapenemase.
·· Only one PCR tube B: Hybridization control; CI: Internal control; BG: DNA quality control (Human beta-globin gene)
·· Uracil-DNA Glycosylase to avoid contamination with PCR
products

MTBc: Mycobacterium tuberculosis complex; SPNEU: Streptococcus

pneumoniae; AGAL: Streptococcus agalactiae; CRYP: Cryptococcus neoformans
(fungus); HINF: Haemophilus influenzae; LIS: Listeria monocytogenes;
TPA: Treponema pallidum; NEISS: Neisseria meningitidis;
COX: Coxiella burnetii; BOR: Borrelia burgdorferi.

B: Hybridization control; CI: Internal control;

BG: DNA quality control (Human beta-globin gene)

TICK-BORNE BACTERIA FLOW CHIP

·· Simultaneous detection of 7 tick-borne bacteria genera
·· The first product for multiplex molecular identification of
tick-borne bacteria
·· Compatible with human, animal and tick samples
VIRAL CNS FLOW CHIP GR: Rickettsia; TG: Rickettsia Typhus Group; SFG: Rickettsia Spotted Fever
Group; EH: Erhlichia; AN: Anaplasma; FR: Francisella; BAR: Bartonella;
·· Simultaneous detection (in one step RT-PCR) of 8 DNA BAR-2: Bartonella-2; BOR: Borrelia; COX: Coxiella.
and RNA viruses causing CNS infections. B: Hybridization control; CI: Internal control;
·· Only one PCR tube BG: DNA quality control (Human beta-globin gene)
·· Uracil-DNA Glycosylase to avoid contamination with PCR
products
·· Validated with External Quality Control Programs QCMD
and UKNEQAS

HSV-1: Herpes Simplex Virus -1; HSV-2: Herpes Simplex Virus -2;
CMV: Cytomegalovirus; EBV: Epstein Barr Virus; VZV: Varicella-Zoster Virus;
TOSV: Toscana Virus; EV: Enterovirus; HPeV: Parechovirus.

B: Hybridization control; CI: Internal control;

BG: DNA quality control (Human beta-globin gene)