Argon - Ar - PubChem PDF

COMPOUND SUMMARY
Argon
Cite Download
CONTENTS
Please visit the Argon element page for information specific to the chemical element of the periodic table. Title and Summary
1 Structures
PubChem CID: 23968 2 Names and Identifiers
3 Chemical and Physical Properties
4 Spectral Information
5 Related Records
Structure: 6 Chemical Vendors
7 Drug and Medication Information

2D
8 Food Additives and Ingredients
Find Similar Structures
9 Pharmacology and Biochemistry
10 Use and Manufacturing
11 Safety and Hazards

Chemical Safety:
Compressed 12 Toxicity
Gas
13 Literature
Laboratory Chemical Safety Summary (LCSS) Datasheet
14 Patents
Molecular Formula: Ar
Argon
7440-37-1
Argon-40
Synonyms: argon atom
Ar
More...
Molecular Weight: 39.9 g/mol
Modify: Create:
Dates:
2019-10-12 2005-08-08
Argon(0) is a monoatomic argon. It has a role as a member of food packaging gas and a neuroprotective agent.
from ChEBI
Argon appears as a colorless odorless noncombustible gas. Heavier than air and can asphyxiate by displacement of
air. Exposure of the container to prolonged heat or fire can cause it to rupture violently and rocket . If liquefied,
contact of the very cold liquid with water may cause violent boiling. If the water is hot, there is the possibility that a
liquid "superheat" explosion may occur. Contacts with water in a closed container may cause dangerous pressure to
build.
from CAMEO Chemicals
Inert atmosphere for wine and fruit or vegetable juice containers. Generally recognised as safe (GRAS) in the US.
from Human Metabolome Database (HMDB)
1 Structures
1.1 2D Structure
Find Similar Structures Get Image Download
Chemical Structure
Depiction
Cite Download
CONTENTS
Title and Summary
1 Structures
2 Names and Identifiers
5 Related Records
6 Chemical Vendors
from PubChem

1.2 Crystal Structures 9 Pharmacology and Biochemistry

PDBe Ligand Code AR
12 Toxicity
13 Literature
14 Patents
PDBe Conformer
from Protein Data Bank in Europe (PDBe)
2.1 Computed Descriptors
2.1.1 IUPAC Name
argon
from PubChem
2.1.2 InChI
InChI=1S/Ar
from PubChem
2.1.3 InChI Key
XKRFYHLGVUSROY-UHFFFAOYSA-N
from PubChem
2.1.4 Canonical SMILES
[Ar]
from PubChem
2.2 Molecular Formula

Ar
from EU Food Improvement Agents; PubChem
2.3 Other Identifiers
2.3.1 CAS Cite Download
7440-37-1 CONTENTS
from ChemIDplus; EPA Chemicals under the TSCA; EPA DSSTox; European Chemicals Agency (ECHA); HSDB; Human Metabolome Database (HMDB); ILOSummary
Title and International Chemical Safety Cards (ICSC)
1 Structures
1290046-39-7 2 Names and Identifiers
from EPA DSSTox 3 Chemical and Physical Properties
13965-95-2
5 Related Records
from EPA DSSTox 6 Chemical Vendors

2.3.1 Other CAS
13473-05-7, 137736-93-7, 24494-51-7, 50938-66-4, 75714-55-5, 239084-98-1, 245503-61-1
from ChemIDplus
12 Toxicity
13 Literature
2.3.2 European Community (EC) Number
14 Patents
EC Number
231-147-0
from EU Food Improvement Agents; European Chemicals Agency (ECHA)
2.3.3 ICSC Number
0154
from ILO International Chemical Safety Cards (ICSC)
2.3.4 UN Number
1006
from CAMEO Chemicals; DOT Emergency Response Guidebook; NJDOH RTK Hazardous Substance List
1951
from CAMEO Chemicals; ILO International Chemical Safety Cards (ICSC)
2.3.5 UNII
67XQY1V3KH
from FDA/SPL Indexing Data
2.3.6 Wikipedia
Argon
from Wikipedia
2.4 Synonyms
2.4.1 MeSH Entry Terms
Argon
Argon 40
Argon-40
from MeSH
2.4.2 Depositor-Supplied Synonyms
Argon E938 18Ar LS-21630

7440-37-1 Argon, >=99.998% AC1L2N4B E 938
Argon compressed [UN1006] [Nonflammable gas]
Argon, compressed [UN1006] [Nonflammable gas]
Argon-40 Argon, Elemental E-938
HSDB 7902 DTXSID3052482 FT-0693043
argon atom
CHEBI:49474 Argon, refrigerated liquid (cryogeni
Ar Argon, compressed
Argon, compressed [UN1006] [Nonf
UNII-67XQY1V3KH Cyclopentene-4-one CHEBI:49475
argon(0) 1290046-39-7 CTK2H7064 Argon, refrigerated liquid (cryogeni
EINECS 231-147-0 13965-95-2 DTXSID30435907 Argon, refrigerated liquid (cryogeni
UN1006 14163-25-8 DTXSID40931147 Cite Download
UN1951 (~36~Ar)Argon DTXSID90745913
67XQY1V3KH (~41~Ar)Argon XKRFYHLGVUSROY-UHFFFAOYSA-N CONTENTS
Argon-40Ar [Ar] Argon, 99.999%, Messer(R) CANGas
Title and Summary
1 Structures
from PubChem
3 Chemical and Physical Properties 4 Spectral Information
5 Related Records
3.1 Computed Properties 6 Chemical Vendors
Property Name Property Value 8 Food Additives and Ingredients
Molecular Weight 39.9 g/mol 9 Pharmacology and Biochemistry
Hydrogen Bond Donor Count 0 10 Use and Manufacturing
Hydrogen Bond Acceptor Count 0 11 Safety and Hazards
Rotatable Bond Count 0 12 Toxicity
Exact Mass 39.962383 g/mol 13 Literature
Monoisotopic Mass 39.962383 g/mol 14 Patents
Topological Polar Surface Area 0 A^2
Heavy Atom Count 1
Formal Charge 0
Complexity 0
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes
from PubChem
3.2 Experimental Properties
3.2.1 Physical Description
Argon appears as a colorless odorless noncombustible gas. Heavier than air and can asphyxiate by displacement of air.
Exposure of the container to prolonged heat or fire can cause it to rupture violently and rocket . If liquefied, contact of the
very cold liquid with water may cause violent boiling. If the water is hot, there is the possibility that a liquid "superheat"
explosion may occur. Contacts with water in a closed container may cause dangerous pressure to build.
Argon, refrigerated liquid (cryogenic liquid) appears as a colorless noncombustible liquid. Heavier than air. Contact may
cause frostbite. May cause asphyxiation by displacement of air. Prolonged exposure to fire or intense heat may cause the
container to rupture violently and rocket.
Liquid
from EPA Chemicals under the TSCA; Human Metabolome Database (HMDB)
Colourless, odourless, non-flammable gas
from EU Food Improvement Agents
ODOURLESS COLOURLESS LIQUEFIED GAS.
3.2.2 Color/Form
Colorless monatomic gas

Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 99
from HSDB
3.2.3 Odor
Cite Download
Odorless
Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 99 CONTENTS
from HSDB Title and Summary
1 Structures

3.2.4 Taste
Tasteless 4 Spectral Information

Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 99 5 Related Records
from HSDB 6 Chemical Vendors

3.2.5 Boiling Point
-185.847 deg C 10 Use and Manufacturing
Lide, D.R. CRC Handbook of Chemistry and Physics 88TH Edition 2007-2008. CRC Press, Taylor & Francis, Boca Raton, FL 2007, p. 4-49 11 Safety and Hazards
from HSDB 12 Toxicity
13 Literature
-185.9 °C
14 Patents
3.2.6 Melting Point
-186.36 deg C triple point (69 kPa)

Lide, D.R. CRC Handbook of Chemistry and Physics 88TH Edition 2007-2008. CRC Press, Taylor & Francis, Boca Raton, FL 2007, p. 4-49
from HSDB
-189.4°C
-189.2 °C
3.2.7 Solubility
Soluble in organic liquids

O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc.,
2006., p. 128
from HSDB
Solubility of gas in water at 20 deg C: 33.6 cu cm/kg water

2006., p. 128
from HSDB
Argon is two and one half times as soluble in water as nitrogen, having about the same solubility as oxygen.
from HSDB
Slightly soluble in water

from HSDB
Solubility in water, ml/100ml at 20 °C: 3.4
3.2.8 Density
1.633 g/L
from HSDB
3.2.9 Vapor Density

Cite Download
1.38 (Air = 1)
Lewis, R.J. Sr.; Hawley's Condensed Chemical Dictionary 15th Edition. John Wiley & Sons, Inc. New York, NY 2007., p. 99 CONTENTS
from HSDB Title and Summary
1 Structures
Relative vapor density (air = 1): 1.66 2 Names and Identifiers
from ILO International Chemical Safety Cards (ICSC) 3 Chemical and Physical Properties
5 Related Records
3.2.10 Octanol/Water Partition Coefficient
6 Chemical Vendors
LogP 7 Drug and Medication Information
0.74 8 Food Additives and Ingredients
from Human Metabolome Database (HMDB) 9 Pharmacology and Biochemistry

LogP 11 Safety and Hazards
0.94 12 Toxicity
from ILO International Chemical Safety Cards (ICSC) 13 Literature
14 Patents
3.2.11 Heat of Vaporization
Liquid (normal BP): 6469 J/mol; Solid: (triple pt): 7.785 kJ/mol.
2006., p. 128
from HSDB
3.2.12 Other Experimental Properties
A noble gas characterized by an electronic structure in which the outer p subshell is entirely filled
2006., p. 128
from HSDB
Naturally occurring argon is a mixture of three isotopes. Seventeen radioactive isotopes are now known to exist.
from HSDB
It is not known to combine chemically with any element, but forms a stable clathrate with beta-hydroquinone.
from HSDB
Will form compounds with highly electromagnetic elements such as O, F, Cl.
2006., p. 128
from HSDB
Specific volume = 9.7 cu ft/lb (21.1 deg C at 1 atm)

from HSDB
An asphyxiant gas
from HSDB
Inert gas. Critical density: 535.7 kg/cu m

2006., p. 128
from HSDB
Gas: density: 1.7838 kg/cum at 101.3 kPa, 0 deg C; 5.767 kg/cu m at normal boiling point
2006., p. 128
from HSDB
Liquid: normal BP: -185.87 deg C, density (normal BP): 1393.9 kg/cu m; at triple point: 1415 kg/cu m
O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., Cite Download
2006., p. 128
CONTENTS
from HSDB
Title and Summary
Solid: density (triple point): 1623 kg/cu m; heat of fusion (triple point):1.191 kJ/mol, exists as face-centered cubic crystals 1 Structures
at normal pressure 2 Names and Identifiers
O'Neil, M.J. (ed.). The Merck Index - An Encyclopedia of Chemicals, Drugs, and Biologicals. Whitehouse Station, NJ: Merck and Co., Inc., 3 Chemical and Physical Properties
2006., p. 128
from HSDB
5 Related Records
6 Chemical Vendors
Argon Decay Pathways [See
Isotope Relative % Abundance Half-life
Argon-36 0.3365 Stable 9 Pharmacology and Biochemistry
Argon-38 0.0632 Stable 10 Use and Manufacturing

Argon-40 99.6003 Stable 11 Safety and Hazards
]
12 Toxicity
Korea Atomic Energy Research Institute. Nuclear Data Evaluation Lab. 2000. Nuclide Table. Available from, as of Feb 11, 2011:
http://atom.kaeri.re.kr/ton/ 13 Literature
from HSDB 14 Patents
Isotope Half-life Mode of Decay Decay Energy (MeV)
Argon-30 Unknown
Argon-31 15 milli-seconds Electron capture to Cl-31 18.360
Argon-33 173.0 milli-seconds Electron capture to Cl-33 11.620
Argon-34 844.5 milli-seconds Electron capture to CL-34 6.061
Argon-35 1.775 seconds Electron capture to Cl-35 5.965
Argon-37 35.04 days Electron capture to Cl-37 0.813
Argon-39 269 years beta to K-39 0.565
Argon-41 109.34 minutes beta to K-41 2.492
Argon-42 32.9 years beta to K-42 0.600
Argon-45 21.48 seconds beta to K-45 6.890
Argon-47 approximately 700 milli-seconds beta to K-47 9.790
Argon 48 unknown
Argon-49 => 170 nano-seconds
Argon-51 >200 nano-seconds
Argon-52
Argon-53
]
http://atom.kaeri.re.kr/ton/
from HSDB
4.1 Mass Spectrometry
4.1.1 MS-MS
MS-MS MS-MS Spectrum 75570 - HMDB HMDB0037240

MS-MS Spectrum 75571 - HMDB HMDB0037240
4.2 Other Spectra

Argon is recognized by the characteristic lines in the red end of the spectrum. Cite Download
CONTENTS
from HSDB
Title and Summary
1 Structures
5 Related Records 2 Names and Identifiers

5.1 Related Compounds with Annotation 4 Spectral Information
5 Related Records
6 Chemical Vendors
12 Toxicity
13 Literature
14 Patents
from PubChem
5.2 Related Compounds
Same Connectivity 7 Records
Mixtures, Components, and

296 Records
Neutralized Forms
Similar Compounds 256 Records
from PubChem
5.3 Related Element
Element Name Argon
Element Symbol Ar
Atomic Number 18
from PubChem Elements
5.4 Substances
5.4.1 Related Substances
All 418 Records
Same 52 Records
Mixture 366 Records
from PubChem
5.4.2 Substances by Category

Cite Download
from PubChem
CONTENTS
Title and Summary

5.5 Entrez Crosslinks
1 Structures
Protein Structures 5 Records 2 Names and Identifiers

from PubChem
5 Related Records
6 Chemical Vendors 6 Chemical Vendors
12 Toxicity
13 Literature
14 Patents
from PubChem
7.1 Drug Indication

Treatment of perinatal asphyxia
from EU Community Register of Medicinal Products
7.2 Clinical Trials
7.2.1 NIPH Clinical Trials Search of Japan
from NIPH Clinical Trials Search of Japan
7.3 Therapeutic Uses

The argon plasma coagulator is a device used for noncontact thermal coagulation of tissue. The device was first used in
open and laparoscopic surgical procedures and in 1991 was adapted for use in endoscopy. Since then, argon plasma
coagulation has expanded its clinical applications in the treatment of various gastrointestinal conditions. ...
PMID:17038840
Malick KJ et al; Gastroenterol Nurs 29 (5): 386-91 (2006)
from HSDB
8.1 Food Additive Classes Cite Download
JECFA Functional Classes CONTENTS
Food Additives: PROPELLANT Title and Summary
from FAO/WHO Food Additive Evaluations (JECFA) 1 Structures

8.2 Evaluations of the Joint FAO/WHO Expert Committee on Food
Additives - JECFA 4 Spectral Information
5 Related Records
Chemical Name ARGON 6 Chemical Vendors
from FAO/WHO Food Additive Evaluations (JECFA) 7 Drug and Medication Information

9 Pharmacology and Biochemistry 10 Use and Manufacturing

9.1 Human Metabolite Information
12 Toxicity
9.1.1 Metabolite Description 13 Literature
14 Patents
Description
Inert atmosphere for wine and fruit or vegetable juice containers. Generally recognised as safe (GRAS) in the US.
9.1.2 Cellular Locations
Cytoplasm
Extracellular
10.1 Use Classification
EU Pharmaceutical Product
Human drug
Classes
from EU Community Register of Medicinal Products
JECFA Functional Classes Food Additives: PROPELLANT
from FAO/WHO Food Additive Evaluations (JECFA)
10.2 Uses
EPA CPDat Chemical and Product Categories
from EPA Chemical and Products Database (CPDat)
Use Classification
Food additives
from EU Food Improvement Agents
Argon is used as an inert gas shield in arc welding, as an inert gas to fill electric lamps, as a blanketing agent in metals
refining (especially titanium and zirconium), in ionization chambers and particle counters, and in doping semiconductors
Cite Download
with controlled amounts of impurities.
American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's with Other World Wide Occupational
CONTENTS
Exposure Values. CD-ROM Cincinnati, OH 45240-4148 2010.
Title and Summary
from HSDB
1 Structures
Argon is used primarily by the semiconductor industry as an inert atmosphere for growing single silicon cystals. Argon is 2 Names and Identifiers
also used as an atmosphere during ion-implant procedures and during annealing, a process to repair substrate damage 3 Chemical and Physical Properties
after ion implantation takes place. 4 Spectral Information
Daigle S et al; Ullmann's Encyclopedia of Industrial Chemistry 7th ed. (2010). New York, NY: John Wiley & Sons; Electronic Chemicals.
5 Related Records
Online Posting Date: June 15, 2000
6 Chemical Vendors
from HSDB

Gas as shield in gas metal-arc welding; in metal processing; carrier in gas-liquid and gas-solid chromatography; gas filler
for incandescent light bulbs. Gas in fluorescent tubes analogous to neon lights, but produces a blue-purplish light; in 9 Pharmacology and Biochemistry
rectified tubes; in thermometers above mercury; in lasers; wherever an inert atmosphere is desired and the much cheaper 10 Use and Manufacturing
nitrogen cannot be used; in ionization chambers and particle counters; in mixtures with He and Ne in Geiger counters; in
argon-oxygen-decarburizing process for stainless steel; in manufacture of semiconducting devices; in gas mixtures as the
working fluid in plasma arc devices. Liquid as cryogen to produce low temperatures. The isotope As(40) is always found in 12 Toxicity
minerals containing potassium, since it is a product of K(40) decay; measuring the amount of AS(40) and K(40) can be 13 Literature
used for determining the geologic age of minerals and meteors.
14 Patents
2006., p. 128
from HSDB
10.3 Methods of Manufacturing

Virtually all commercial production of argon is the result of oxygenic separation of atmospheric gases.
Daigle S et al; Ullmann's Encyclopedia of Industrial Chemistry 7th ed. (2010). New York, NY: John Wiley & Sons; Electronic Chemicals.
Online Posting Date: June 15, 2000
from HSDB
(1) By fractional distillation of liquid air. (2) By the treatment of atmosphere nitrogen with metals such as magnesium and
calcium to form nitrides. (3) Recovery formed natural gas oxidation bottoms-steam in ammonia plant. (4) Originally form
by radioactive decay of K40.
from HSDB
10.4 Formulations/Preparations
Grade: Technical, highest purity (99.9995%)
from HSDB
10.5 U.S. Production

Aggregated Product Volume (EPA CDR 2016)
10,000,000 - 50,000,000 lb
https://www.epa.gov/chemical-data-reporting
from EPA Chemicals under the TSCA
World production in 1975 was 700,000 tonnes for use mainly as an inert atmosphere in high-temperature metallurgical
processes and , in smaller amounts, for filing incandescent lamps. By 1993, production has increased considerably and
716,000 tonnes were produced in the USA alone.
Greenwood NN, Earnshaw A; Chemistry of the Elements. 2nd ed., Boston, MA: Butterworth Heinemann p. 891 (1977)
from HSDB
Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Argon.
Aggregated National Production Volume: < 500,000 lbs.
US EPA; Non-Confidential 2006 Inventory Update Reporting. National Chemical Information. Argon (7440-37-1). Available from, as of
February 23, 2011: http://cfpub.epa.gov/iursearch/index.cfm?s=chem&err=t
from HSDB
10.6 Manufacturers
Airgas Merchant Gases, LLS, 6055 Rockside Woods Blvd., 5th Floor, Independence, OH 44131, (610) 687-5253 [See
Address City State, Zip Phone
Cite Download
80 Stockhouse Rd. Bozrah, CT 06334 (860) 889-5974
2505 Shepler Church Road, S.W. Canton, OH 44706 (330) 454-7755

CONTENTS
1240 Stripling Chapel Rd. Carrollton, GA 30117 (770) 838-1229
Title and Summary
109 Tom Harris Rd. Carrollton, KY 41008 (502) 732-4430
1 Structures
3800 Dayton Park Dr. Dayton, OH 45414 (937) 237-0621
180 Frontage Rd. Gaston, SC 29053 (803) 791-7685
1629 Possum Creek Rd. Jefferson, GA 30549 (706) 693-4773
1302 South West 112th St. Lawton, OK 73505 (580) 536-7634
5 Related Records
4802 Pflaum Rd. Madison, WI 53704 (608) 223-9080
6 Chemical Vendors
500 Industrial Park Dr. Mulberry, AR 72947 (479) 997-2578
54354 Walnut Rd. New Carlisle, IN 46552 (574) 654-3682
309 Sentry Dr. Waukesha, WI 53186 (262) 547-6465
]
SRI Consulting, 2010 Directory of Chemical Producers. Menlo Park, CA. 2010, p. 439 10 Use and Manufacturing
from HSDB 11 Safety and Hazards
12 Toxicity
Air Liquide America L.P., 2700 Post Oak Blvd., Suite 1800, Houston, TX 77056, (713) 624-8000 [See 13 Literature
Address City State, Zip Phone 14 Patents
6510 Arctic Spur Rd./ 6514 Arctic Blvd. Anchorage , AK 99518 (907) 561-1520
Beaumont, TX 77704 (409) 724-8250
815 McHenry St. Burlington, WI 53105 (262) 767-1280
2000 Sheldon Rd. Channelview, TX 77530 (281) 452-4766
Lower Modena Rd. Coatesville, PA 19320 (610) 384-8107
13140 Floyd Rd. Dallas, TX 75243
P.O. Box 272 Denver, CO 19706
91-163 Hanua St. Ewa Beach, HI 96707 (808) 682-2151
Fairfield, AL 35064
1711 FM523 Freeport, TX 77541 (409) 239-5250
Geismar, LA 70734
Ghent, KY 41045
Hahnville, LA 70057
Holland, OH 43528
Ingleside, TX 78362
8008 222nd St. Kent, WA 98031
11450 Fairmont Parkway La Porte, TX 77571 (281) 474-8470
722 FM 1845 Longview, TX 75602 (903) 237-1740
McMinnville, OR 97128
7248 S.W. 29th St., Route 5 Oklahoma City, OK 73128
Orlando, FL 32824
11400 Bay Area Blvd. Pasadena, TX 77507 (281) 474-8300
Pittsboro, IN 46167
57805 Evergreen Rd. Plaquemine, LA 70764 (504) 685-4241
Port Neches, TX 77651
Provo, UT 84601
Spartanburg, SC 29301
3900 Hwy. 27 South Sulphur, LA 70663 (318) 583-2849
Tucson, AZ 85714
Union City, CA 94587

]
SRI Consulting, 2010 Directory of Chemical Producers. Menlo Park, CA. 2010, p. 439
from HSDB
Air Liquide America L.P., Merchant Products Group, 3 Great Valley Pkwy., Malvern, PA 19355-1424, (610) 695-7400 [See
Albany, NY 12210
Berkeley, SC 29450
Blythevill, AR 72310
Chattanooga, TN 37409
Hertford, SC 29532
Mapleton, IL 61547
Middletown, OH 45042 Cite Download
Mount Vernon, IN 47620

CONTENTS
New Johnsonville, TN 37134
Title and Summary
Norfolk, NE 68701
1 Structures
Reading, PA 19603
St. Marys, PA 15857
300 Alumax Dr. Texarkana, TX 75501
Wake Forest, NC 27587
5 Related Records
West Point, VA 23181
] 6 Chemical Vendors
SRI Consulting, 2010 Directory of Chemical Producers. Menlo Park, CA. 2010, p. 439 7 Drug and Medication Information
from HSDB 8 Food Additives and Ingredients

Air Products and Chemicals, Inc., 7201 Hamilton Blvd., Allentown, PA 18195-1501, (610) 481-4911; Industrial Gases 10 Use and Manufacturing
Division, (610) 481-6099 [See
Address City State, Zip Phone 12 Toxicity
125 Russell Rd. Ashland, KY 41101 (806) 324-7921 13 Literature
Baltimore, MD 21219 14 Patents
5503 W. Baker Rd. Baytown, TX 77520 (281) 838-0202
745 S. Frontage Rd. Bountiful, UT 84014 (801) 298-4881
4590 County Rd. 59 Butler, IN 46721 (260) 868-9145
4900 Este Ave Cincinnati, OH 45232 (513) 242-5246
2820 Quigley Rd. Cleveland, OH 44113
P.O. Box 79 Coden, AL 36523 (334) 873-4873
Convent, LA 70700
Conyers, GA 30012
P.O. Box 2083 Decatur, AL 35601
El Segundo, CA 90245
Glenmont, NY 12077
P.O. Box 695 Granite City, IL 62040
La Porte, TX 77571
P.O. Box 556 Middletown, OH 45042
Milwaukee, WI 53246
P.O. Box 175 North Baltimore, OH 45872
Orlando, FL 32800
Pryor, OK 74361
Puyallup, WA 98371
Reidsville, NC 27320
P.O. Box 4061 Sparrows Point, MD 21219
]
from HSDB
East Coast Oxygen Co., 1101 Market St., Bethlehem, PA 18017, (610) 317-8500; Production site: Bethlehem, PA 18018
from HSDB
The Linde Group, 6055 Rockside Woods Blvd., Independence, OH 44131, (216) 642-6600; BOC Gases Division, 575
Mountain Avenue, Murray Hill, NJ 07974, (908) 464-8100 [See
85 Airco Blvd. Aiken, SC 29801
257 U.S. 71 South Ashdown, AR 71822
3616 Seventh Avenue North Birmingham, AL 35222
1000 Washington Ave Braddock, PA 15104
101 Katheriine St., P.O. Box 1035, Station D Buffalo, NY 14210
660 North Baldwin Park Blvd. City of Industry, CA 91746
6000 Philadelphia Pike Claymount, DE 19703

Coffeyville, KS 67337
Columbus, MS 39701
Star Highway 225 Elko, NV 89801
Route 5 Box 66B Enid, OK 73701 Cite Download
76 West Yard Rd. Feura Bush, NY 12067

CONTENTS
405 East Zeller Rd. Fostoria, OH 44830
Title and Summary
Harper, TX 78631
1 Structures
P.O. Box 37 Hartford, TX 62048
1045 Harding Court Indianapolis, IN 46217
9 Ranger Dr., P.O. Box 220 Kittery, ME 03904
3794 42nd St. Lanett, AL 36863
5 Related Records
7996 State HIghway 39 North La Porte, IN 46530
4301 Hurricane Creek Blvd. Nashville, TN 37200 6 Chemical Vendors
5858 88th St. Sacramento, CA 95828 7 Drug and Medication Information
300 Metro Dr. Terrell, TX 75160 (972) 563-1294 8 Food Additives and Ingredients
5840 South Memorial, Suite 3003 Tulsa, OK 74133 9 Pharmacology and Biochemistry
4715 N.E. 78th St. Vancouver, WA 98665 10 Use and Manufacturing
Warren, OH 44481 11 Safety and Hazards
Washington, VA 26181-9713 (304) 863-8086 12 Toxicity
Fourth & St. John Rd. Weirton, WV 26062 13 Literature
] 14 Patents
from HSDB
Linweld, Inc., 2900 South 70th St., Suite 400, Lincoln, NE 68506, (402) 323-8450; Production site: Waverly, NE 68462
from HSDB
Matheson Tri-Gas, Inc., 959 Route 46 East, Parsippany, NJ 07054, (973) 257-1100 [See
8200 Washington N.E. Albuquerque, NM 87113 (505) 823-2606
7635 Kiln-Delisle Rd. DeLisile, MS 39571 (228) 255-6661
5420 Valley View Lane Irving, TX 75038 (972) 252-8488
16125 Ornelas St. Irwindale, CA 91706 (626) 334-2905
18000 Beeline Highway Jupiter, FL 33478 (561) 775-0080
2121 E I-20 Service Rd. Odessa, TX 79766 (915) 335-0205
13440 Bay Area Blvd. Pasadena, TX 77507 (281) 474-5336
10430 Mula Rd. Stafford, TX 77477 (281) 495-0773
871 Eubanks Dr. Vacaville, CA 95688 (707) 447-5753
Vernon, CA 90058
3680 North I-35 East Waxahachie, TX 75165 (972) 923-9953
2745 Houston River Rd. Westlake, LA 70669 (337) 439-6544

]
from HSDB
Praxair, Inc., 39 Old Ridgebury Rd., Danbury, CT 06810-5113, (203) 837-3000 [See
Ashtabula, OH 44004
Camden, SC 29020
2225 Bolivar Rd., S.W. Canton, OH 44706 (330) 453-9904
Cape Kennedy, FL 32754
Circleville, OH 43113
Curtis Bay, MD 21226
Deer Park, TX 77536
Delaware City, DE 19706
East Chicago, IN 46312
Ecorse, MI 48229
Fife, WA 98424
Gasden, AL 35917
Garfield, UT 84100
Garland, TX 75000
Gary, IN 46406
Groves, TX 77619 Cite Download
Hampton, VA 23600
CONTENTS
Hatfield, PA 19440
Title and Summary
Humacao, PR 00791
1 Structures
Kansas City, MO 64123
La Porte, TX 77500
3076 N. State Rd. 39 La Porte, IN 46350 (219) 326-7910
Lorain, OH 44055
5 Related Records
Loveland, CO 80537
6 Chemical Vendors
Marietta, OH 45750
Memphis, TN 38100
Minneapolis, MN 55413 8 Food Additives and Ingredients
Neosho, MO 64850 9 Pharmacology and Biochemistry
New Hanover, NC 28401 10 Use and Manufacturing
New Johnsonville, TN 37134 11 Safety and Hazards
P.O. Box 2268 Niagara Falls, NY 14300 12 Toxicity
2000 Loveridge Rd. Pittsburg CA 94565 13 Literature
Plaquemmine, LA 70765 14 Patents
416 Center St. Stockerton, PA 18013 (610) 759-9215
Suffield, CT 06078
Texas City, TX 77590
Theodore, AL 36582
Wilmington, CA 90744
]
from HSDB
Procal, 8934 Dice Rd., Santa Fe Springs, CA 90670, (562) 944-3873; Production site: Santa Fe Springs, CA 90670
from HSDB
Argon - Company and Production data 2006 [See
Company Production Site City, State, Zip Manufacture Import
Ford Motor Company Ford Motor Co - Sterling Plant. Sterling Heights MI 48310 no Yes
]
US EPA; Inventory Update Reporting (IUR). Non-confidential 2006 IUR Records by Chemical, including Manufacturing, Processing and Use
Information. Washington, DC: U.S. Environmental Protection Agency. Available from, as of Feb 18, 2011:
http://cfpub.epa.gov/iursearch/index.cfm
from HSDB
10.7 General Manufacturing Information

EPA TSCA Commercial Activity Status
Argon: ACTIVE
https://www.epa.gov/tsca-inventory
from EPA Chemicals under the TSCA
Argon is a noble gas, i.e. monatomic, non-polar

from HSDB
Method of purification: (1) Highly purified argon is obtained by passing the gas through a bed of titanium at 850 deg C.
(2) Synthetic zeolite molecular sieves separate oxygen from argon to give high purity gas.
from HSDB
Obtained commercially from the atmosphere by distillation-liquefaction process

2006., p. 128
from HSDB
11.1 Hazards Identification Cite Download
CONTENTS
11.1.1 GHS Classification
Title and Summary
Showing 1 of 2 View More
1 Structures

Pictogram(s)
Compressed 4 Spectral Information
Gas
5 Related Records
Signal Warning
6 Chemical Vendors
Aggregated GHS information provided by 423 companies from 11 notifications to the ECHA C&L
Inventory. Each notification may be associated with multiple companies.
Reported as not meeting GHS hazard criteria by 4 of 423 companies. For more detailed information, 8 Food Additives and Ingredients
please visit ECHA C&L website 9 Pharmacology and Biochemistry
Of the 10 notification(s) provided by 419 of 423 companies with hazard statement code(s):
GHS Hazard Statements H280 (67.54%): Contains gas under pressure; may explode if heated [Warning Gases under pressure]
H281 (35.08%): Contains refrigerated gas; may cause cryogenic burns or injury [Warning Gases under
pressure] 12 Toxicity
Information may vary between notifications depending on impurities, additives, and other factors. The 13 Literature
percentage value in parenthesis indicates the notified classification ratio from companies that provide
hazard codes. Only hazard codes with percentage values above 10% are shown. 14 Patents
Precautionary Statement P282, P315, P336, P403, and P410+P403

Codes (The corresponding statement to each P-code can be found at the GHS Classification page.)
from European Chemicals Agency (ECHA)
11.1.2 Health Hazard
Excerpt from ERG Guide 121 [Gases - Inert]: Vapors may cause dizziness or asphyxiation without warning. Vapors from
liquefied gas are initially heavier than air and spread along ground. (ERG, 2016)
U.S. Department of Transportation, Transport Canada, and Secretariat of Communications and Transport of Mexico, with collaboration
from Argentina's Centro de Información Química para Emergencias. 2016 Emergency Response Guidebook.
https://www.phmsa.dot.gov/hazmat/outreach-training/erg (accessed April 26, 2016).
Excerpt from ERG Guide 120 [Gases - Inert (Including Refrigerated Liquids)]: Vapors may cause dizziness or asphyxiation
without warning. Vapors from liquefied gas are initially heavier than air and spread along ground. Contact with gas or
liquefied gas may cause burns, severe injury and/or frostbite. (ERG, 2016)
11.1.3 Fire Hazard
Excerpt from ERG Guide 121 [Gases - Inert]: Non-flammable gases. Containers may explode when heated. Ruptured
cylinders may rocket. (ERG, 2016)
Excerpt from ERG Guide 120 [Gases - Inert (Including Refrigerated Liquids)]: Non-flammable gases. Containers may
explode when heated. Ruptured cylinders may rocket. (ERG, 2016)
Not combustible. Heating will cause rise in pressure with risk of bursting.
11.2 Safety and Hazard Properties

11.2.1 Critical Temperature & Pressure
Critical temperature: 150.86 K; critical pressure: 4898 kPa

2006., p. 128
from HSDB Cite Download
CONTENTS
11.2.2 Physical Dangers Title and Summary
The gas is heavier than air and may accumulate in lowered spaces causing a deficiency of oxygen. 1 Structures
from ILO International Chemical Safety Cards (ICSC) 2 Names and Identifiers
11.2.3 Explosive Limits and Potential 5 Related Records
Exposure of the container to prolonged heat or fire can cause it to rupture violently and rocket. /Argon, compressed; 6 Chemical Vendors
Argon, refrigerated liquid/ 7 Drug and Medication Information
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation. 8 Food Additives and Ingredients
Association of American Railroads, Pueblo, CO. 2005, p. 88
from HSDB
11.3 First Aid Measures 12 Toxicity
13 Literature
11.3.1 First Aid 14 Patents
Excerpt from ERG Guide 121 [Gases - Inert]: Ensure that medical personnel are aware of the material(s) involved and take
precautions to protect themselves. Move victim to fresh air. Call 911 or emergency medical service. Give artificial
respiration if victim is not breathing. Administer oxygen if breathing is difficult. Keep victim calm and warm. (ERG, 2016)
Excerpt from ERG Guide 120 [Gases - Inert (Including Refrigerated Liquids)]: Ensure that medical personnel are aware of
the material(s) involved and take precautions to protect themselves. Move victim to fresh air. Call 911 or emergency
medical service. Give artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult. Clothing
frozen to the skin should be thawed before being removed. In case of contact with liquefied gas, thaw frosted parts with
lukewarm water. Keep victim calm and warm. (ERG, 2016)
11.3.2 Inhalation First Aid
Fresh air, rest. Artificial respiration may be needed. Refer for medical attention.
11.3.3 Skin First Aid
ON FROSTBITE: rinse with plenty of water, do NOT remove clothes. Refer for medical attention .
11.3.4 Eye First Aid
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical
attention.
11.4 Fire Fighting

Excerpt from ERG Guide 121 [Gases - Inert]: Use extinguishing agent suitable for type of surrounding fire. Move containers
from fire area if you can do it without risk. Damaged cylinders should be handled only by specialists. FIRE INVOLVING
TANKS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Cool containers with
flooding quantities of water until well after fire is out. Do not direct water at source of leak or safety devices; icing may
occur. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay
away from tanks engulfed in fire. (ERG, 2016)
Excerpt from ERG Guide 120 [Gases - Inert (Including Refrigerated Liquids)]: Use extinguishing agent suitable for type of Cite Download
surrounding fire. Move containers from fire area if you can do it without risk. Damaged cylinders should be handled only
by specialists. FIRE INVOLVING TANKS: Fight fire from maximum distance or use unmanned hose holders or monitor CONTENTS
nozzles. Cool containers with flooding quantities of water until well after fire is out. Do not direct water at source of leak
Title and Summary
or safety devices; icing may occur. Withdraw immediately in case of rising sound from venting safety devices or
discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016) 1 Structures
U.S. Department of Transportation, Transport Canada, and Secretariat of Communications and Transport of Mexico, with collaboration 2 Names and Identifiers
5 Related Records
6 Chemical Vendors
In case of fire in the surroundings, use appropriate extinguishing media.
11.4.1 Fire Fighting Procedures 10 Use and Manufacturing

If material involved in fire: Extinguish fire using agent suitable for type of surrounding fire. Material itself does not burn or
burns with difficulty. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as 12 Toxicity
possible. /Argon, compressed; Argon, refrigerated liquid/ 13 Literature
Association of American Railroads; Bureau of Explosives. Emergency Handling of Hazardous Materials in Surface Transportation.
14 Patents
from HSDB
If material involved in fire: Do not use water on material itself. /Argon, refrigerated liquid/
from HSDB
Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special protective
equipment for fire-fighters: Wear self contained breathing apparatus for fire fighting if necessary.
Sigma-Aldrich; Material Safety Data Sheet for Argon. Product Number 295000. Version 3.0 (August 2009). Available from, as of March 3,
2011: http://www.sigmaaldrich.com/safety-center/msds-search.html
from HSDB
11.5 Accidental Release Measures
11.5.1 Isolation and Evacuation
Excerpt from ERG Guide 121 [Gases - Inert]: As an immediate precautionary measure, isolate spill or leak area for at least
100 meters (330 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 100 meters (330
feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also,
consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Excerpt from ERG Guide 120 [Gases - Inert (Including Refrigerated Liquids)]: As an immediate precautionary measure,
isolate spill or leak area for at least 100 meters (330 feet) in all directions. LARGE SPILL: Consider initial downwind
evacuation for at least 100 meters (330 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters
(1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
11.5.2 Spillage Disposal
Personal protection: self-contained breathing apparatus. Ventilation. NEVER direct water jet on liquid.
11.5.3 Cleanup Methods

Personal precautions: Avoid breathing vapors, mist or gas. Environmental precautions: No special environmental
precautions required. Methods for cleaning up: Wipe up with absorbent material (e.g. cloth, fleece).
from HSDB
Cite Download
CONTENTS
11.5.4 Disposal Methods
Title and Summary
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for
1 Structures
occupational harm/injury/toxicity or environmental contamination. Recycle any unused portion of the material for its
approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's 2 Names and Identifiers
impact on air quality; potential migration in soil or water; effects on animal and plant life; and conformance with 3 Chemical and Physical Properties
environmental and public health regulations. 4 Spectral Information
from HSDB 5 Related Records
6 Chemical Vendors

11.5.5 Preventive Measures
If material not involved in fire: Do not use water on material itself. /Argon, refrigerated liquid/
from HSDB
12 Toxicity
13 Literature
If material not involved in fire: Attempt to stop leak it without undue personnel hazard. /Argon, compressed; Argon,
refrigerated liquid/ 14 Patents
from HSDB
Personnel protection: Avoid breathing vapors. Keep upwind. Do not handle broken packages unless wearing appropriate
personal protective equipment. /Argon, compressed; Argon, refrigerated liquid/
from HSDB
If breathed in, move person into fresh air. If not breathing give artificial respiration In case of skin contact: Wash off with
soap and plenty of water. In case of eye contact: Flush eyes with water as a precaution. If swallowed: Never give anything
by mouth to an unconscious person. Rinse mouth with water.
from HSDB
11.6 Handling and Storage
11.6.1 Nonfire Spill Response
Excerpt from ERG Guide 121 [Gases - Inert]: Do not touch or walk through spilled material. Stop leak if you can do it
without risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled
material. Do not direct water at spill or source of leak. If possible, turn leaking containers so that gas escapes rather than
liquid. Prevent entry into waterways, sewers, basements or confined areas. Allow substance to evaporate. Ventilate the
area. (ERG, 2016)
Excerpt from ERG Guide 120 [Gases - Inert (Including Refrigerated Liquids)]: Do not touch or walk through spilled material.
Stop leak if you can do it without risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water
runoff to contact spilled material. Do not direct water at spill or source of leak. If possible, turn leaking containers so that
gas escapes rather than liquid. Prevent entry into waterways, sewers, basements or confined areas. Allow substance to
evaporate. Ventilate the area. CAUTION: When in contact with refrigerated/cryogenic liquids, many materials become
brittle and are likely to break without warning. (ERG, 2016)
11.6.2 Safe Storage

Fireproof if in building. Keep in a well-ventilated room.
11.6.3 Storage Conditions

Cite Download
Keep container tightly closed in a dry and well-ventilated place. Contents under pressure.
CONTENTS
2011: http://www.sigmaaldrich.com/safety-center/msds-search.html Title and Summary
from HSDB 1 Structures

11.7 Exposure Control and Personal Protection
5 Related Records
11.7.1 Threshold Limit Values (TLV)
6 Chemical Vendors
Simple asphyxiant. /A simple asphyxiant may not be assigned a TLV because the limiting factor is the available oxygen./
American Conference of Governmental Industrial Hygienists TLVs and BEIs. Threshold Limit Values for Chemical Substances and Physical
Agents and Biological Exposure Indices. Cincinnati, OH 2010, p. 12
from HSDB
11.7.2 Inhalation Risk 12 Toxicity
On loss of containment this substance can cause suffocation by lowering the oxygen content of the air in confined areas. 13 Literature
14 Patents
11.7.3 Effects of Short Term Exposure
Asphyxiation. The liquid may cause frostbite.
11.7.4 Radiation Limits and Potential
Isotope Half-life Mode of Decay Decay Energy (MeV)
Argon-30 Unknown
Argon-33 173.0 milli-seconds Electron capture to Cl-33 11.620
Argon-34 844.5 milli-seconds Electron capture to CL-34 6.061
Argon-35 1.775 seconds Electron capture to Cl-35 5.965
Argon-37 35.04 days Electron capture - Cl-37 0.813
Argon-39 269 years beta to K-39 0.565
Argon-42 32.9 years beta to K-42 0.600
Argon-47 approximately 700 milli-seconds beta to K-47 9.790
Argon 48 unknown
Argon-51 >200 nano-seconds
Argon-52
Argon-53
]
from HSDB
Argon-36 0.3365 Stable


]
Cite Download
from HSDB CONTENTS
Title and Summary

ALI values have been established for individual radionuclides and are presented in Table 1 in Appendix B to PART 20.1001-
1 Structures
20.2401. The ALI values for inhalation, presented in Column 2 in Table 1, correspond to a committed effective dose
equivalent of 5 rems (0.05 Sv) or a committed dose equivalent of 50 rems (0.5 Sv) to any individual organ or tissue, 2 Names and Identifiers
whichever is more limiting. If the ALI value presented in Table 1 is limited by the 50-rem committed dose equivalent, the 3 Chemical and Physical Properties
controlling organ is listed directly below the ALI value, and the stochastic ALI value based on the 5-rem committed
effective dose equivalent is listed ... directly below the organ name. If a stochastic ALI is listed in parentheses, that value
5 Related Records
should be used to calculate the committed effective dose equivalent.
6 Chemical Vendors
U.S. Nuclear Regulatory Commission; Regulatory Guide 8.34 - Monitoring Criteria and Methods to Calculate Occupational Radiation
Doses. 1992. Available from, as of September 25, 2006: http://www.nrc.gov/reading-rm/doc-collections/reg-guides/occupational- 7 Drug and Medication Information
health/active/8-34/
from HSDB

OCCUPATIONAL VALUES FOR ARGON (Class Submersion) [See
RADIONUCLIDE ORAL Ingestion ALI (uCi) INHALATION ALI (uCi) INHALATION DAC (uCi/mL)
12 Toxicity
Argon-37 - - 1E+0 13 Literature
Argon-39 - - 2E-4 14 Patents
Argon-41 - - 3E-6
]
U.S. Nuclear Regulatory Commission; Table 1, Appendix B to Part 20--Annual Limits on Intake (ALIs) and Derived Air Concentrations
(DACs) of Radionuclides for Occupational Exposure. Available from, as of March 31, 2011: http://www.nrc.gov/reading-rm/doc-
collections/cfr/part020/appb/
from HSDB
EFFLUENT CONCENTRATIONS ESTABLISHED BY THE NRC FOR SOME ARGON COMPOUNDS [See
RADIONUCLIDE EFLUENT CONCENTRATION: Air (uCi/mL) EFFLUENT CONCENTRATION: Water (uCi/mL)
Argon-37 6E-3 -
Argon-39 8E-7 -
Argon-41 1E-8 -
]
U.S. Nuclear Regulatory Commission; Table 2, Appendix B to Part 20--Effluent Concentrations Available from, as of March 31, 2011:
http://www.nrc.gov/reading-rm/doc-collections/cfr/part020/appb/
from HSDB
QUANTITIES OF NRC LICENSED MATERIAL REQUIRING LABELING [See
RADIONUCLIDE QUANTITY (uCi)
Argon-39 1,000
Argon-41 1,000
]
U.S. Nuclear Regulatory Commission; 10 CFR Appendix C to Part 20--Quantities of Licensed Material Requiring Labeling. Available from,
as of March 31, 2011: http://www.nrc.gov/reading-rm/doc-collections/cfr/part020/part020-appc.html
from HSDB
11.7.5 Personal Protective Equipment (PPE)
Personnel protection: Wear appropriate chemical protective gloves and goggles. /Argon, compressed; Argon, refrigerated
liquid/
from HSDB
Eye protection: Safety glasses.

from HSDB
For prolonged or repeated contact use protective gloves.

from HSDB
Respiratory protection is not required. Where protection is desired, use multi-purpose combination (US) or type AXBEK
(EN 14387) respirator cartridges. Use respirators and components tested and approved under appropriate government
standards such as NIOSH (US) or CEN (EU).
Sigma-Aldrich; Material Safety Data Sheet for Argon. Product Number 295000. Version 3.0 (August 2009). Available from, as of March 3, Cite Download
CONTENTS
from HSDB
Title and Summary
1 Structures
11.7.6 Inhalation Prevention 2 Names and Identifiers
Use ventilation. 3 Chemical and Physical Properties
from ILO International Chemical Safety Cards (ICSC) 4 Spectral Information
5 Related Records
6 Chemical Vendors
11.7.7 Skin Prevention 7 Drug and Medication Information
Cold-insulating gloves. Protective clothing. 8 Food Additives and Ingredients
from ILO International Chemical Safety Cards (ICSC) 9 Pharmacology and Biochemistry

11.7.8 Eye Prevention
12 Toxicity
Wear safety goggles or face shield. 13 Literature
from ILO International Chemical Safety Cards (ICSC) 14 Patents
11.7.9 Protective Equipment and Clothing
Excerpt from ERG Guide 121 [Gases - Inert]: Wear positive pressure self-contained breathing apparatus (SCBA). Structural
firefighters' protective clothing will only provide limited protection. (ERG, 2016)
Excerpt from ERG Guide 120 [Gases - Inert (Including Refrigerated Liquids)]: Wear positive pressure self-contained
breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection. Always wear
thermal protective clothing when handling refrigerated/cryogenic liquids or solids. (ERG, 2016)
11.8 Stability and Reactivity
11.8.1 Air and Water Reactions
No rapid reaction with air. No rapid reaction with water.
11.8.2 Reactive Group
Not Chemically Reactive
11.8.3 Reactivity Profile
These substances undergo no chemical reactions under any known circumstances. They are nonflammable,
noncombustible and nontoxic. They can asphyxiate.
These substances undergo no chemical reactions under any known circumstances. They are nonflammable,
noncombustible and nontoxic. They can asphyxiate. Contact of very cold liquefied gas with water may result in vigorous or
violent boiling of the product and extremely rapid vaporization due to the large temperature differences involved. If the
water is hot, there is the possibility that a liquid "superheat" explosion may occur. Pressures may build to dangerous levels
if liquid gas contacts water in a closed container [Handling Chemicals Safely 1980].

11.9 Transport Information
11.9.1 DOT Emergency Guidelines
/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ Health: Vapors may cause dizziness or asphyxiation
Cite Download
without warning. Vapors from liquefied gas are initially heavier than air and spread along ground. Contact with gas or
liquefied gas may cause burns, severe injury and/or frostbite. /Argon, refrigerated liquid (cryogenic liquid)/
CONTENTS
U.S. Department of Transportation. 2008 Emergency Response Guidebook. Washington, D.C. 2008
Title and Summary
from HSDB
1 Structures

/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ Fire or Explosion: Non-flammable gases. Containers
may explode when heated. Ruptured cylinders may rocket. /Argon, refrigerated liquid (cryogenic liquid)/ 3 Chemical and Physical Properties
U.S. Department of Transportation. 2008 Emergency Response Guidebook. Washington, D.C. 2008 4 Spectral Information
5 Related Records
from HSDB
6 Chemical Vendors
/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ Public Safety: CALL Emergency Response Telephone 7 Drug and Medication Information
Number ... As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all 8 Food Additives and Ingredients
directions. Keep unauthorized personnel away. Stay upwind. Many gases are heavier than air and will spread along ground
and collect in low or confined areas (sewers, basements, tanks). Keep out of low areas. Ventilate closed spaces before
entering. /Argon, refrigerated liquid (cryogenic liquid)/ 10 Use and Manufacturing
U.S. Department of Transportation. 2008 Emergency Response Guidebook. Washington, D.C. 2008 11 Safety and Hazards
from HSDB 12 Toxicity
13 Literature
/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ Protective Clothing: Wear positive pressure self- 14 Patents
contained breathing apparatus (SCBA). Structural firefighters' protective clothing will only provide limited protection.
Always wear thermal protective clothing when handling refrigerated/cryogenic liquids or solids. /Argon, refrigerated liquid
(cryogenic liquid)/
from HSDB
/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ Evacuation: Large spill: Consider initial downwind
evacuation for at least 100 meters (330 feet). Fire: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters
(1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. /Argon, refrigerated
liquid (cryogenic liquid)/
from HSDB
/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ Fire: Use extinguishing agent suitable for type of
surrounding fire. Move containers from fire area if you can do it without risk. Damaged cylinders should be handled only
by specialists. Fire involving tanks: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles.
Cool containers with flooding quantities of water until well after fire is out. Do not direct water at source of leak or safety
devices; icing may occur. Withdraw immediately in case of rising sound from venting safety devices or discoloration of
tank. ALWAYS stay away from tanks engulfed in fire. /Argon, refrigerated liquid (cryogenic liquid)/
from HSDB
/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ Spill or Leak: Do not touch or walk through spilled
material. Stop leak if you can do it without risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid
allowing water runoff to contact spilled material. Do not direct water at spill or source of leak. If possible, turn leaking
containers so that gas escapes rather than liquid. Prevent entry into waterways, sewers, basements or confined areas.
Allow substance to evaporate. Ventilate the area. CAUTION: When in contact with refrigerated/cryogenic liquids, many
materials become brittle and are likely to break without warning. /Argon, refrigerated liquid (cryogenic liquid)/
from HSDB
/GUIDE 120: GASES - INERT (INCLUDING REFRIGERATED LIQUIDS)/ First Aid: Move victim to fresh air. Call 911 or
emergency medical service. Give artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult.
Clothing frozen to the skin should be thawed before being removed. In case of contact with liquefied gas, thaw frosted
parts with lukewarm water. Keep victim warm and quiet. Ensure that medical personnel are aware of the material(s)
involved and take precautions to protect themselves. /Argon, refrigerated liquid (cryogenic liquid)/
from HSDB
/GUIDE 121: GASES - INERT/ Health: Vapors may cause dizziness or asphyxiation without warning. Vapors from liquefied
gas are initially heavier than air and spread along ground. /Argon; Argon, compressed/
from HSDB
/GUIDE 121: GASES - INERT/ Fire or Explosion: Non-flammable gases. Containers may explode when heated. Ruptured
cylinders may rocket. /Argon; Argon, compressed/
from HSDB
Cite Download
/GUIDE 121: GASES - INERT/ Public Safety: CALL Emergency Response Telephone Number ... As an immediate
precautionary measure, isolate spill or leak area for at least 100 meters (330) in all directions. Keep unauthorized personnel CONTENTS
away. Stay upwind. Many gases are heavier than air and will spread along ground and collect in low or confined areas
Title and Summary
(sewers, basements, tanks). Keep out of low areas. Ventilate closed spaces before entering. /Argon; Argon, compressed/
1 Structures
from HSDB
/GUIDE 121: GASES - INERT/ Protective Clothing: Wear positive pressure self-contained breathing apparatus (SCBA).
Structural firefighters' protective clothing will only provide limited protection. /Argon; Argon, compressed/ 5 Related Records
U.S. Department of Transportation. 2008 Emergency Response Guidebook. Washington, D.C. 2008 6 Chemical Vendors
from HSDB 7 Drug and Medication Information
/GUIDE 121: GASES - INERT/ Evacuation: Large spill: Consider initial downwind evacuation for at least 100 meters (300 9 Pharmacology and Biochemistry
feet). Fire: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider
initial evacuation for 800 meters (1/2 mile) in all directions. /Argon; Argon, compressed/
12 Toxicity
from HSDB
13 Literature
14 Patents
/GUIDE 121: GASES - INERT/ Fire: Use extinguishing agent suitable for type of surrounding fire. Move containers from fire
area if you can do it without risk. Damaged cylinders should be handled only by specialists. Fire involving tanks: Fight fire
from maximum distance or use unmanned hose holders or monitor nozzles. Cool containers with flooding quantities of
water until well after fire is out. Do not direct water at source of leak or safety devices; icing may occur. Withdraw
immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks
engulfed in fire. /Argon; Argon, compressed/
from HSDB
/GUIDE 121: GASES - INERT/ Spill or Leak: Do not touch or walk through spilled material. Stop leak if you can do it without
risk. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material.
Do not direct water at spill or source of leak. If possible, turn leaking containers so that gas escapes rather than liquid.
Prevent entry into waterways, sewers, basements or confined areas. Allow substance to evaporate. Ventilate the area.
/Argon; Argon, compressed/
from HSDB
/GUIDE 121: GASES - INERT/ First Aid: Move victim to fresh air. Call 911 or emergency medical service. Give artificial
respiration if victim is not breathing. Administer oxygen if breathing is difficult. Keep victim warm and quiet. Ensure that
medical personnel are aware of the material(s) involved and take precautions to protect themselves. /Argon; Argon,
compressed/
from HSDB
11.9.2 DOT ID and Guide
1006 121
from DOT Emergency Response Guidebook
11.9.3 DOT Label
Non-Flammable Gas
11.9.4 UN Classification
UN Hazard Class: 2.2
12 Toxicity
12.1 Toxicological Information

12.1.1 Exposure Routes
The substance can be absorbed into the body by inhalation.
Cite Download
12.1.2 Inhalation Symptoms

CONTENTS
Dizziness. Lethargy. Headache. Suffocation. Title and Summary
from ILO International Chemical Safety Cards (ICSC) 1 Structures

12.1.3 Skin Symptoms
ON CONTACT WITH LIQUID: FROSTBITE. 5 Related Records
from ILO International Chemical Safety Cards (ICSC) 6 Chemical Vendors

12.1.4 Eye Symptoms
ON CONTACT WITH LIQUID: FROSTBITE. 10 Use and Manufacturing
from ILO International Chemical Safety Cards (ICSC) 11 Safety and Hazards
12 Toxicity
13 Literature
12.1.5 Antidote and Emergency Treatment
14 Patents
Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial
respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR
as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs,
lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent
aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Simple asphyxiants and
related compounds/
Currance, P.L. Clements, B., Bronstein, A.C. (Eds).; Emergency Care For Hazardous Materials Exposure. 3Rd edition, Elsevier Mosby, St. Louis,
MO 2005, p. 92
from HSDB
Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary.
Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask
at 10 to 15 L/min. Anticipate seizures and treat if necessary ... . Use rapid rewarming techniques if frostbite occurs ... .
/Simple asphyxiants and related compounds/
MO 2005, p. 439-40
from HSDB
Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious
or is in severe respiratory distress. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of
D5W /SRP: "To keep open", minimal flow rate/. Treat seizures with diazepam or lorazepam ... . /Simple asphyxiants and
related compounds/
MO 2005, p. 440
from HSDB
12.1.6 Human Toxicity Excerpts
/SIGNS AND SYMPTOMS/ Contact with the liquid will cause frostbite./Argon, refrigerated liquid/
from HSDB
/CASE REPORTS/ A 31-year-old engineer was found dead in a reaction vessel (diameter 0.8 m, height 1.8 m) of a bulb
factory some minutes after he had entered it for repair work. Resuscitation attempts with artificial respiration were
unsuccessful. Despite autopsy and usual toxicological analyses, no cause of death could be found. Since in the normal
production process, argon was used as a protecting gas, the possibility of suffocation in an argon atmosphere was
investigated. This was rendered more difficult because of the natural content of 0.93 vol.% argon in air and since the
excessive argon could have been removed by the resuscitation attempts. Gas samples from larynx, esophagus, bronchi,
and stomach, separated blood samples from both ventricles of the heart and from the vena iliaca externa as well as tissue
samples from lung and liver were collected during autopsy into headspace vials in such a way that the loss of gas and a
dilution by surrounding air was avoided as far as possible. The samples were analyzed by headspace GC-MS. The
abundance of Ar+ (m/z = 40) was used for quantification with N2(2+) (m/z = 14) as internal standard. The following argon
concentrations were measured (mean values, case under investigation/comparison cases): gas from larynx 1.79/0.96 vol.%,
stomach gas 1.58/0.89 vol.%, heart blood (left ventricle) 7.2/2.7 microg/mL, heart blood (right ventricle) 5.8/2.7 microg/mL,
blood from vena iliaca externa 3.6/2.7 microg/mL. A clearly increased concentration was also found in lung tissue, whereas
in liver tissue no significant difference in comparison to other cases was measured. From the results, it follows that the
deceased inhaled an increased amount of argon a short time before death. The concentrations are consistent with
asphyxia and subsequent resuscitation attempts. ...
PMID:15240039
Auwarter V et al; Forensic Sci Int 143 (2-3): 169-75 (2004)
from HSDB Cite Download
CONTENTS
/CASE REPORTS/ ... /A/ fatality from argon gas emboli during prostate cryosurgery /is reported/. The decedent underwent
cryotherapy for prostate carcinoma using cryoablation probes which were cooled with argon and nitrous oxide and Title and Summary
warmed with helium. Minutes into the procedure he experienced sudden cardiovascular collapse and could not be 1 Structures
resuscitated. Postmortem examination was performed ... . Collection of tissues and blood samples had to be conducted
carefully to capture suspected noble gases, argon, and helium. Specimens were submitted ... for toxicological examination
and for evaluation of the composition of the gas retrieved from the vascular system. Gas chromatography mass 3 Chemical and Physical Properties
spectrometric analyses confirmed argon in blood, brain, liver, and gas retrieved from the aorta. These samples had 4 Spectral Information
significant argon compared with room air also sent for comparison. The manner of death was accident. ...[Sandomirsky M
5 Related Records
et al; Am J Forensic Med Pathol. 2010 May 21.
6 Chemical Vendors
PMID:20498594
Epub ahead of print]
from HSDB

12.1.7 Non-Human Toxicity Excerpts 11 Safety and Hazards
/LABORATORY ANIMALS: Acute Exposure/ ... Carbon dioxide, argon, and nitrogen /were compared/ for inducing 12 Toxicity
unconsciousness and euthanasia of Sprague-Dawley rats. We determined time to unconsciousness and monitored heart 13 Literature
rate and mean arterial blood pressure by radiotelemetry to assess stress, recovery after exposure, and time of death.
14 Patents
Unconsciousness (mean +/- standard error) occurred 24 +/- 3, 87 +/- 8, and 93 +/- 8 seconds after short-term exposure
to carbon dioxide, argon, and nitrogen, respectively. During exposure, carbon dioxide depressed heart rate, whereas
argon and nitrogen increased heart rate. Upon removal from the chamber, rats' heart rate rapidly normalized after carbon
dioxide or nitrogen but remained elevated for 60 min after argon. During exposure, all agents depressed MAP, which
returned to resting levels 10 to 50 min after rats removal from the chamber. For euthanasia, carbon dioxide at
approximately 100% induced unconsciousness in 37 +/- 3 seconds, increased and then depressed mean arterial blood
pressure and heart rate, and caused death at 188 +/- 15 seconds. Carbon dioxide at approximately 30% induced
unconsciousness in 150 +/- 15 seconds, decreased heart rate and mean arterial blood pressure, and induced death at 440
+/- 9 seconds. Argon at approximately 100% increased mean arterial blood pressure but decreased heart rate, induced
unconsciousness with hyperreflexia at 54 +/- 4 seconds, and caused death at 197 +/- 20 seconds. Nitrogen at
approximately 100% decreased mean arterial blood pressure but not heart rate and produced unconsciousness with
hyperreflexia at 164 +/- 17 seconds and death at 426 +/- 28 seconds. ... Carbon dioxide effectively produced
unconsciousness and euthanasia, but we were unable to ascertain distress. Argon also appears effective but produced
hyperreflexia and tachycardia. Nitrogen was ineffective.
PMID:16542038
Sharp J et al; J Am Assoc Lab Anim Sci 45 (2): 21-5 (2006)
from HSDB
12.2 Ecological Information
12.2.1 Natural Pollution Sources
Stable naturally occurring isotopes (mass numbers): 36 (0.377%); 38 (0.063%); 40 (99.600%) ... Abundance in igneous rock
of the earth's crust: 4X10-2 ppm by weight ... The isotope As(40) is always found in minerals containing potassium, since it
is a product of K(40) decay.
2006., p. 128
from HSDB
In the earth's atmosphere, noble gases make up about 1% ... argon is their major component.
from HSDB
The atmosphere of Mars contains 1.6% of argon-40 and 5 ppm of argon-36.

from HSDB
12.2.2 Environmental Water Concentrations
GROUNDWATER: Argon concentrations ranged from 13.1 to 17.2 micromoles/L (median 15.5 micromoles/L) in samples of
groundwater from Orangeburg County, SC, collected in November 1997(1). Argon was reported at a concentration range
of 0.7515 to 1.0923 mg/L in ground water samples taken at Mirror Lake, New Hampshire in 1991 and 1992(2).
(1) Puckett LJ, Hughes WB; J Environ Qual 34: 2278-2292 (2205) (2) Busenberg E, Plummer LN; in USGS Toxic Substances Hydrology
Program. Proc. Tech. Mtg., Colorado Springs, CO., Sept. 20-24, 1993. USGS Water Res. Invet. Report 94-4015., Morganwalp DW, Aronson
DA, eds. pp. 151-158 (1994)
from HSDB
12.2.3 Atmospheric Concentrations
Concentration in atmosphere: 93.40 ppm by volume

Cite Download
2006., p. 128
CONTENTS
from HSDB
Title and Summary
1 Structures
The atmosphere of Mars contains 1.6% of argon-40 and 5 ppm of argon-36.
from HSDB
5 Related Records
12.2.4 Probable Routes of Human Exposure 6 Chemical Vendors

According to the 2006 TSCA Inventory Update Reporting data, the number of persons reasonably likely to be exposed in
the industrial manufacturing, processing, and use of argon is 1 to 99; the data may be greatly underestimated(1).
(1) US EPA; Inventory Update Reporting (IUR). Non-confidential 2006 IUR Records by Chemical, including Manufacturing, Processing and
Use Information. Washington, DC: U.S. Environmental Protection Agency. Available from, as of Feb 18, 2011: 10 Use and Manufacturing
http://cfpub.epa.gov/iursearch/index.cfm
from HSDB
12 Toxicity
13 Literature
13 Literature 14 Patents
13.1 NLM Curated PubMed Citations
from PubChem
13.2 Metabolite References
13.3 Chemical Co-Occurrences in Literature

Cite Download
CONTENTS
Title and Summary
1 Structures

from PubChem 3 Chemical and Physical Properties
5 Related Records
13.4 Chemical-Disease Co-Occurrences in Literature
6 Chemical Vendors
12 Toxicity
13 Literature
14 Patents
from PubChem
13.5 Chemical-Gene Co-Occurrences in Literature
from PubChem
14 Patents
14.1 Depositor-Supplied Patent Identifiers

from PubChem
Link to all deposited patent identifiers
from PubChem
Cite Download
CONTENTS
15 Biomolecular Interactions and Pathways
Title and Summary
1 Structures
15.1 Protein Bound 3-D Structures
5 Related Records
6 Chemical Vendors
12 Toxicity
13 Literature
14 Patents
from PDB
View 5 proteins in NCBI Structure
from PubChem
16 Classification
16.1 Ontologies
16.1.1 MeSH Tree
from MeSH
16.1.2 ChEBI Ontology

from ChEBI
16.1.3 WIPO IPC Cite Download
CONTENTS
Title and Summary
1 Structures
5 Related Records
6 Chemical Vendors

from WIPO
12 Toxicity
13 Literature
16.1.4 ChemIDplus 14 Patents
from ChemIDplus
16.1.5 CAMEO Chemicals
16.1.6 UN GHS Classification

Cite Download
CONTENTS
Title and Summary

from UN Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
1 Structures
16.1.7 EPA CPDat Classification 3 Chemical and Physical Properties
5 Related Records
6 Chemical Vendors
12 Toxicity
13 Literature
14 Patents
from EPA Chemical and Products Database (CPDat)
17 Information Sources
FILTER BY SOURCE ALL SOURCES
1. CAMEO Chemicals
ARGON
https://cameochemicals.noaa.gov/chemical/9251
ARGON, REFRIGERATED LIQUID (CRYOGENIC LIQUID)

https://cameochemicals.noaa.gov/chemical/2509
CAMEO Chemical Reactivity Classification
https://cameochemicals.noaa.gov/browse/react
2. DOT Emergency Response Guidebook

argon
https://www.phmsa.dot.gov/hazmat/erg/emergency-response-guidebook-erg
3. ILO International Chemical Safety Cards (ICSC)

ARGON
http://www.ilo.org/dyn/icsc/showcard.display?p_version=2&p_card_id=0154
4. NJDOH RTK Hazardous Substance List

argon
http://nj.gov/health/eoh/rtkweb/documents/fs/0151.pdf
5. EPA Chemicals under the TSCA

LICENSE
https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources
Argon
https://www.epa.gov/chemicals-under-tsca
6. EU Food Improvement Agents

ARGON
https://eur-lex.europa.eu/legal-content/EN/ALL/?uri=CELEX%3A32012R0231
7. Human Metabolome Database (HMDB)

Argon
http://www.hmdb.ca/metabolites/HMDB0037240
8. ChEBI
Argon(0)
http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:49474
ChEBI Ontology
http://www.ebi.ac.uk/chebi/userManualForward.do#ChEBI%20Ontology
9. ChemIDplus
Argon, Elemental
https://chem.nlm.nih.gov/chemidplus/sid/0007440371
ChemIDplus Chemical Information Classification
https://chem.sis.nlm.nih.gov/chemidplus/
10. EPA DSSTox

Argon
https://comptox.epa.gov/dashboard/DTXSID3052482
Argon-40Ar
https://comptox.epa.gov/dashboard/DTXSID30435907 Cite Download
(~36~Ar)Argon
https://comptox.epa.gov/dashboard/DTXSID90745913 CONTENTS
11. European Chemicals Agency (ECHA) Title and Summary
LICENSE 1 Structures
Use of the information, documents and data from the ECHA website is subject to the terms and conditions of this Legal Notice, and subject to
other binding limitations provided for under applicable law, the information, documents and data made available on the ECHA website may be 2 Names and Identifiers
reproduced, distributed and/or used, totally or in part, for non-commercial purposes provided that ECHA is acknowledged as the source: "Source:
European Chemicals Agency, http://echa.europa.eu/". Such acknowledgement must be included in each copy of the material. ECHA permits and 3 Chemical and Physical Properties
encourages organisations and individuals to create links to the ECHA website under the following cumulative conditions: Links can only be made
to webpages that provide a link to the Legal Notice page. 4 Spectral Information
https://echa.europa.eu/web/guest/legal-notice
5 Related Records
argon
https://echa.europa.eu/substance-information/-/substanceinfo/100.028.315
6 Chemical Vendors
Argon 7 Drug and Medication Information

https://echa.europa.eu/information-on-chemicals/cl-inventory-database/-/discli/details/85110
12. HSDB 9 Pharmacology and Biochemistry
Argon, Elemental
https://toxnet.nlm.nih.gov/cgi-bin/sis/search/r?dbs+hsdb:@term+@rn+@rel+7440-37-1 10 Use and Manufacturing

13. EPA Chemical and Products Database (CPDat)
12 Toxicity
LICENSE
https://www.epa.gov/privacy/privacy-act-laws-policies-and-resources 13 Literature
argon 14 Patents
https://comptox.epa.gov/dashboard/DTXSID3052482#exposure
EPA CPDat Classification
https://www.epa.gov/chemical-research/chemical-and-products-database-cpdat
14. EU Community Register of Medicinal Products

Argon
https://ec.europa.eu/health/documents/community-register/html/o2031.htm
15. FAO/WHO Food Additive Evaluations (JECFA)

ARGON
http://apps.who.int/food-additives-contaminants-jecfa-database/chemical.aspx?chemID=1861
16. NITE-CMC
Argon
http://www.safe.nite.go.jp/english/ghs/09-mhlw-0120e.html
17. FDA/SPL Indexing Data

67XQY1V3KH
https://www.fda.gov/ForIndustry/DataStandards/SubstanceRegistrationSystem-UniqueIngredientIdentifierUNII/
18. NIPH Clinical Trials Search of Japan

https://rctportal.niph.go.jp/en/
19. PDB
http://www.rcsb.org/ligand/AR
20. Protein Data Bank in Europe (PDBe)

http://www.ebi.ac.uk/pdbe-srv/pdbechem/chemicalCompound/show/AR
21. PubChem Elements

Argon
https://pubchem.ncbi.nlm.nih.gov/element/Argon
22. Wikipedia
Argon
https://en.wikipedia.org/wiki/Argon
23. MeSH
Argon
https://www.ncbi.nlm.nih.gov/mesh/68001128
MeSH Tree
http://www.nlm.nih.gov/mesh/meshhome.html
24. PubChem
https://pubchem.ncbi.nlm.nih.gov
25. WIPO
International Patent Classification
http://www.wipo.int/classifications/ipc/
26. UN Globally Harmonized System of Classification and Labelling of Chemicals (GHS)

GHS Classification Tree
http://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html

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COMPOUND SUMMARY

PubChem CID: 23968 2 Names and Identifiers

3 Chemical and Physical Properties

Structure: 6 Chemical Vendors

7 Drug and Medication Information

10 Use and Manufacturing

11 Safety and Hazards

Molecular Weight: 39.9 g/mol

Title and Summary

2 Names and Identifiers

3 Chemical and Physical Properties

8 Food Additives and Ingredients

10 Use and Manufacturing

from Protein Data Bank in Europe (PDBe)

2 Names and Identifiers

2.1 Computed Descriptors

2.1.1 IUPAC Name

2.1.3 InChI Key

2.1.4 Canonical SMILES

2.2 Molecular Formula

2.3 Other Identifiers

2.3.1 CAS Cite Download

7 Drug and Medication Information

8 Food Additives and Ingredients

from EU Food Improvement Agents; European Chemicals Agency (ECHA)

2.3.3 ICSC Number

from ILO International Chemical Safety Cards (ICSC)

from CAMEO Chemicals; ILO International Chemical Safety Cards (ICSC)

from FDA/SPL Indexing Data

2.4.1 MeSH Entry Terms

2.4.2 Depositor-Supplied Synonyms

Argon E938 18Ar LS-21630

3 Chemical and Physical Properties

3 Chemical and Physical Properties 4 Spectral Information

3.1 Computed Properties 6 Chemical Vendors

7 Drug and Medication Information

Property Name Property Value 8 Food Additives and Ingredients

Molecular Weight 39.9 g/mol 9 Pharmacology and Biochemistry

Hydrogen Bond Donor Count 0 10 Use and Manufacturing

Hydrogen Bond Acceptor Count 0 11 Safety and Hazards

Rotatable Bond Count 0 12 Toxicity

Exact Mass 39.962383 g/mol 13 Literature

Monoisotopic Mass 39.962383 g/mol 14 Patents

Topological Polar Surface Area 0 A^2

Heavy Atom Count 1

Isotope Atom Count 0

Defined Atom Stereocenter Count 0

Undefined Atom Stereocenter Count 0

Defined Bond Stereocenter Count 0

Undefined Bond Stereocenter Count 0

Covalently-Bonded Unit Count 1

Compound Is Canonicalized Yes

3.2 Experimental Properties

3.2.1 Physical Description

from CAMEO Chemicals

from CAMEO Chemicals

Colourless, odourless, non-flammable gas

from EU Food Improvement Agents

ODOURLESS COLOURLESS LIQUEFIED GAS.

from ILO International Chemical Safety Cards (ICSC)

Colorless monatomic gas

from HSDB Title and Summary

2 Names and Identifiers

Argon-49 => 170 nano-seconds

Argon-50 => 170 nano-seconds

Argon-51 >200 nano-seconds