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J Oral Maxillofac Surg

63:1317-1324, 2005

A Biomechanical Evaluation of
Bilateral Sagittal Ramus Osteotomy
Fixation Techniques
Gilman P. Peterson, DMD,* Richard H. Haug, DDS,† and
Joseph Van Sickels, DDS‡

Objectives: The purpose of this investigation was to evaluate and compare the biomechanical behavior
of various rigid internal fixation plates designed to aid in the condylar positioning of bilateral sagittal
ramus osteotomies, to positional screws in an inverted-L pattern, and a control.
Materials and Methods: Fifty polyurethane synthetic mandible replicas (Synbone, Laudquart, Swit-
zerland) were used in this investigation. Five controls and 5 each of 4 different fixation modalities (3
bicortical positional screws in an inverted-L pattern, monocortical 4-hole straight plates, monocortical
6-hole curved plates, and monocortical adjustable 4-hole slide plates) were subjected to vertical loading
at the incisal edge and torsional loading at the molar region by an Instron 1331 (Instron, Canton, MA)
servohydraulic mechanical testing unit. Mechanical deformation data within a 0 to 900 N range were
recorded. Yield load, yield displacement, and stiffness were determined. Means and standard deviations
were derived and compared for statistical significance using a Fisher’s Protected Least Significant
Differences Test with a confidence level of 95% (P ⬍ .05). Second-order polynomial best-fit curves were
also created for each group to further evaluate mechanical behavior.
Results: For incisal edge loading, statistically significant differences were noted between the control
group and all other groups for yield load and stiffness, and between the control group and straight,
curved, and slide plates for yield displacement. Differences were also noted between the inverted-L and
straight, strut, and slide plates for yield load; and inverted-L and straight, curved, and slide, as well as
straight and slide for yield displacement. For molar loading, statistically significant differences were noted
between the control group and all other groups for yield load and stiffness. Differences were noted
between the slide and straight, curved, and control; as well as between the inverted-L and straight and
strut plates for yield displacement. Lastly, differences were noted between the straight and curved plates,
and the slide and straight, curved, and inverted-L for stiffness.
Conclusion: In this in vitro study, differences were noted between the control and all experimental groups
in their abilities to resist loads under all of the conditions tested. Differences were also noted among specific
experimental groups. Yet when placed in the context of functional parameters, only the bicortical positional
screws in an inverted-L pattern met the requirements for both molar loading and incisal edge loading.
© 2005 American Association of Oral and Maxillofacial Surgeons
J Oral Maxillofac Surg 63:1317-1324, 2005

The bilateral sagittal ramus osteotomy (BSRO) has


been used for the correction of mandibular skeletal
Received from the University of Kentucky College of Dentistry, deformities since the late 1950s.1,2 Since that time,
Lexington, KY. numerous modifications have been promoted to
*Resident in Oral and Maxillofacial Surgery. decrease morbidity, improve surgical convenience,
†Professor of Oral and Maxillofacial Surgery, Executive Associate and provide stability.3-9 With the advent of titanium
Dean. plates and screws, rigid fixation of the BSRO has
‡Division and Program Director. become the standard because it improves stability,
Address correspondence and reprint requests to Dr Haug: Uni- affords a more rapid return to presurgical function,
versity of Kentucky College of Dentistry, 800 Rose St, Room D508, enhances nutritional support, provides for easier
Lexington, KY 40536-0297; e-mail: rhhaug2@pop.uky.edu airway maintenance, and reduces relapse. Histori-
© 2005 American Association of Oral and Maxillofacial Surgeons cally, the biomechanical research regarding BSRO
0278-2391/05/6309-0011$30.00/0 fixation that has been performed over the past few
doi:10.1016/j.joms.2005.05.301
decades has focused on the stability of osteotomy

1317
1318 EVALUATION OF BSRO FIXATION TECHNIQUES

FIGURE 1. Simulated BSRO, advanced, and fixated with 3 2.0-mm FIGURE 2. Simulated BSRO, advanced, and fixated with a 4-hole,
outer thread diameter, 16.0 mm long, self-tapping bicortical screws narrow, straight monocortical plate (Synthes Maxillofacial; 401.366),
(Synthes Maxillofacial; 401.366) in an inverted-L pattern. secured with 4 2.0-mm outer thread diameter, 6.0-mm long monocor-
tical screws (Synthes Maxillofacial; 401.356).
Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation
Techniques. . J Oral Maxillofac Surg 2005. Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation
Techniques. . J Oral Maxillofac Surg 2005.

fixation. Bilateral positional screws have been the


most critically evaluated of BSRO rigid internal fix- secured to the proximal segment, used as a handle for
ation techniques because they are relatively simple condylar positioning and then temporarily fixated
to place and are quite stable.10-22 While bilateral with a monocortical screw and washer. After release
positional screws in an inverted-L pattern (Fig 1) of maxillomandibular fixation, the occlusion can be
have become the “gold standard” by which other verified. If minor modifications are required, they can
fixation techniques have been compared, other pat- be made by adjusting the slide screw, and then finally
terns of screw placement and varying types of permanent fixation can be accomplished with mono-
plates have been the subject of recent biomechani- cortical screws in the distal segment.
cal investigations.23,24 Yet the focus of these inves- The purpose of this investigation was to evaluate
tigations was related solely to the stability of the and compare the biomechanical behavior of a sam-
fixation, without regard to other surgical consider- pling of plate fixation modalities designed to aid in
ations. One such consideration is the ease and abil- condyle positioning during BSSO, to bicortical invert-
ity to appropriately seat the condyles intraopera-
tively, and then to apply fixation accurately,
precisely, and consistently. It has been the experi-
ence of our group that on more than 1 occasion,
after fixation and subsequent release of maxillo-
mandibular fixation, occlusal discrepancies have
occurred because of inaccurate or imprecise fixa-
tion placement.
Recent developments in plate design have provided
for new techniques that have the potential to conve-
niently aid in condylar seating in a 1-step fashion. One
such technique is the use of a monocortical straight
plate. Once monocortically secured to the proximal
segment, the plate can be used as a handle to position
the condyle and then be secured monocortically to
the distal segment (Fig 2). An improvement over that
design has been a curved shape that permits more FIGURE 3. Simulated BSRO, advanced, and fixated with a 6-hole
anatomic adaptation, additional screw holes for stabil- curved, low profile sagittal split plate, with an 8.0-mm bar (Synthes
Maxillofacial; 447.034), secured with 6 2.0-mm outer thread diam-
ity, and graduated marking on the shaft in millimeter eter, 6.0-mm long monocortical screws (Synthes Maxillofacial;
increments to assist in accurate positioning (Fig 3). 401.356).
One last modification is the sagittal split plate with Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation
adjustable slider (Fig 4). This particular plate can be Techniques. . J Oral Maxillofac Surg 2005.
PETERSON, HAUG, AND VAN SICKELS 1319

FIGURE 4. Simulated BSRO, advanced, and fixated with a 33.0-mm


long sagittal split plate with adjustable slider (Synthes Maxillofacial; FIGURE 5. Second order polynomial best-fit curves of load/displace-
447.114) secured with 4 2.0-mm outer thread diameter, 6.0-mm long ment data for incisal edge loading.
monocortical screws (Synthes Maxillofacial; 401.356).
Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation
Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation Techniques. . J Oral Maxillofac Surg 2005.
Techniques. . J Oral Maxillofac Surg 2005.

ed-L positional screw fixation, and a control, using the systems tested to further evaluate and compare
polyurethane synthetic mandible replicas under the differences in mechanical behavior.
benchtop conditions that resembled clinical function.
These synthetic replicas (Synbone, Laudquart, Swit-
zerland) were chosen to eliminate many of the vari- Materials and Methods
ables associated with human cadaveric and animal A total of 50 synthetic polyurethane mandibles
mandibles and have previously been used for biome- (Synbone) were used in this study. To minimize vari-
chanical research.25-30 The polyurethane replicas ables in this investigation, all monocortical screws
have been created from exactly matched human anat- used (Synthes Maxillofacial, West Chester, PA,
omy in all dimensions and proportions.25,26 The mod- 401.356) were 2.0 mm in outer thread diameter, 6.0
els are constructed with a dense outer layer resem- mm in length, fabricated of titanium, and were self-
bling cortical bone, and a porous inner core that tapping. All bicortical screws (Synthes Maxillofacial;
mimics cancellous bone.25,26 The uniformity of these 401.366) were 2.0 mm in outer thread diameter, 16.0
synthetic replicas provides more consistent sampling mm in length, fabricated of titanium, and self-tapping.
than cadaver bone, with a similar modulus of elastic-
ity.31-34 Their use as human bone substitutes has been
evaluated for these types of biomechanical investiga-
tions and has been verified as being acceptable alter-
natives.34 While direct inference to the clinical situa-
tion cannot be made when using human bone
substitutes, experimental trends can be identified.
The parameters evaluated in this investigation were
yield load, yield displacement, and stiffness. Yield
load is that stress at which permanent deformation of
the system begins. Yield displacement is that strain at
which permanent deformation begins. Stiffness is de-
fined as the rate of change of stress as a function of
strain (slope of the load/displacement curve). Each of
these parameters was evaluated under conditions that
simulated function—incisal edge loading (vertical
loads) and molar loading (torsional loads). Data were
gathered, means and standard deviations derived and FIGURE 6. Second order polynomial best-fit curves of load/displace-
then compared for statistical significance. Finally, sec- ment data for molar loading.
ond order polynomial best-fit curves of the load/dis- Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation
placement data (Figs 5 and 6) were created for each of Techniques. . J Oral Maxillofac Surg 2005.
1320 EVALUATION OF BSRO FIXATION TECHNIQUES

Table 1. A DESCRIPTION OF FIXATION TECHNIQUES


(Synthes Maxillofacial; 447.114) (slide group) (Fig 4)
FOR CATEGORIES AND GROUPS secured with 4 2.0-mm outer thread diameter, 6.0-mm
long monocortical screws (Synthes Maxillofacial;
Group Fixation Technique 401.356). The 30 plates and 340 screws were placed
Control No osteotomy or fixation by a single investigator.
Inverted-L Three, 2.0 mm outer thread diameter, 16.0
mm long, self-tapping bicortical screws INCISAL EDGE LOADING
(Synthes Maxillofacial, West Chester, PA; The first portion of this investigation consisted of
401.366) in an inverted-L pattern
Straight Four-hole, narrow, straight monocortical anterior loading at the mandibular incisal edges.
plate (Synthes Maxillofacial; 401.366), Synthetic mandibles (N ⫽ 25) were prepared by
secured with four, 2.0 mm outer thread placing jig receiver holes into the coronoid/ramus
diameter, 6.0 mm long monocortical region in a uniform manner using a standardized jig
screws (Synthes Maxillofacial; 401.356) created from dental stone. Each mandibular replica
Curved Six-hole curved, low profile sagittal split
plate, with an 8.0 mm bar (Synthes was tested only once. Five uncut mandibles served
Maxillofacial; 447.034), secured with six, as controls to define limitations of the substrate
2.0 mm outer thread diameter, 6.0 mm (synthetic mandible replica). Five advanced and
long monocortical screws (Synthes fixated mandibles were used from each of the ex-
Maxillofacial; 401.356) perimental groups. All samples were placed in a
Slide 33.0 mm long sagittal split plate with
adjustable slider (Synthes Maxillofacial; custom-fabricated jig similar to that described by
447.114) secured with four 2.0 mm Dichard and Klotch28 permitting incisal edge load-
outer thread diameter, 6.0 mm long ing. Resistance to proximal segment rotation was
monocortical screws (Synthes provided by a stainless steel rod, 5.0 mm in diam-
Maxillofacial; 401.356) eter, placed through 3 eyelets in the jig and the
Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation coronoid/ramus regions of each mandible. Vertical
Techniques. J Oral Maxillofac Surg 2005. loads were created and measured with an Instron
1331 (Instron Corp, Canton, MA) mechanical test-
ing unit. This servohydraulic materials testing unit
SAMPLE PREPARATION developed a liner displacement at a rate of 5.0 mm
Ten uncut mandible replicas were reserved as con- per minute, and a 13.34 kN load cell measured the
trol models; 5 for incisal edge (vertical) loading and 5 resultant force. Data were acquired at a rate of 10
for molar (torsional) loading. Forty synthetic mandi- Hz and were stored through the use of Instron
bles were selected for the experimental groups. Each software. Loading was continued up to mechanical
experimental mandible had bilateral sagittal split os- failure or the displacement limits of the servohy-
teotomies created by a single investigator. Sagittal draulic testing unit (50.0 mm). The behavior of the
cuts were made using a Stryker TPS reciprocation saw constructs was evaluated within a 0 to 900 N range.
(Stryker Instruments, Kalamazoo, MI) extending from Means and standard deviations were derived and
superior to the lingual into the first molar region. All compared for statistical significance within the fix-
transverse osteotomies were made using a single right ation categories shown in Table 1 using a Fisher’s
or left stone jig. Following the osteotomies the distal Protected Least Significant Differences Test. A P ⬍
segments were advanced 7 mm. A stone jig was used .05 was considered significant. Second order poly-
to ensure consistent positioning of proximal and dis- nomial best-fit curves were then created for each
tal segments. The experimental groups were recon- group to further evaluate and compare the mechan-
structed as follows (Table 1): fixation by 3 2.0-mm ical behavior within and among fixation categories.
outer thread diameter, 16.0-mm long, self-tapping bi-
cortical screws (Synthes Maxillofacial; 401.356) in an MOLAR LOADING
inverted-L pattern (inverted-L group) (Fig 1); a 2.0- The second portion of this investigation consisted
mm, 4-hole, narrow, straight monocortical plate (Syn- of posterior loading at the left mandibular molars. All
thes Maxillofacial; 401.366), secured with 4 2.0-mm mandibles (N ⫽ 25) were prepared by creating a 1.0
outer thread diameter, 6.0-mm long monocortical cm activating arm receptacle fossa between the left
screws (Synthes Maxillofacial; 401.356) (straight first and second molars. Coronoid/ramus receiver
group) (Fig 2); a curved, low profile sagittal split holes were created as previously described. Each
plate, with an 8.0-mm bar (Synthes Maxillofacial; model was tested only once. Five uncut mandibles
447.034) (curved group) (Fig 3), secured with 6 were used as controls. The remaining 5 mandibles
2.0-mm outer thread diameter, 6.0-mm long monocor- from each of the experimental groups were then used
tical screws (Synthes Maxillofacial; 401.356); and a in this experimental section. The same testing jig
33.0-mm long sagittal split plate with adjustable slider described for incisal edge loading was used to secure
PETERSON, HAUG, AND VAN SICKELS 1321

Table 2. SUMMARY OF RESULTS (MEAN ⴞ STANDARD DEVIATION)

Incisal Edge Loading Contralateral Molar Loading


Yield Displacement Yield Displacement
Group Yield Load (N) (mm) Stiffness (N/mm) Yield Load (N) (mm) Stiffness (N/mm)

Control 517.9 ⫾ 162.19 8.2 ⫾ 2.6 65.7 ⫾ 8.3 890.8 ⫾ 310.4 6.6 ⫾ 1.7 164.4 ⫾ 9.9
Inverted-L 143.3 ⫾ 19.93 5.2 ⫾ 2.1 15.4 ⫾ 2.8 352.4 ⫾ 81.5 9.3 ⫾ 3.9 47.2 ⫾ 11.6
Straight 43.93 ⫾ 9.3 5.2 ⫾ 2.1 10.1 ⫾ 3.7 220.8 ⫾ 46.8 6.2 ⫾ 1.5 44.9 ⫾ 7.6
Curved 48.0 ⫾ 10.7 3.9 ⫾ 2.2 16.1 ⫾ 11.6 210.0 ⫾ 69.1 4.7 ⫾ 1.7 57.7 ⫾ 6.9
Slide 27.7 ⫾ 10.3 1.9 ⫾ 1.2 17.4 ⫾ 10.1 345.2 ⫾ 122.6 11.3 ⫾ 1.4 28.5 ⫾ 4.5
Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation Techniques. J Oral Maxillofac Surg 2005.

the condyle/coronoid regions of the mandible repli- observations made. For incisal edge loading, statis-
cas. A curved stainless steel rod, 10.0 mm in diameter, tically significant differences were noted between
was secured to the Instron activator, engaged in the the control group and all other groups for yield load
right molar region, and used to create loads as in the and stiffness, and between the control group and
first portion of the investigation. The Instron unit straight, curved, and slide plates for yield displace-
developed a liner displacement at a rate of 1 mm per ment (Tables 2 and 3). Differences were also noted
minute, and measured the resultant force. Data were between the inverted-L and straight, curved, and
acquired at a rate of 10 Hz and were stored through slide plates for yield load; and inverted-L and
the use of Instron software. Loading was continued straight, curved, and slide, as well as straight and
up to mechanical failure or the displacement limits of slide for yield displacement.
the servohydraulic testing unit (50.0 mm). The me- For molar loading, statistically significant differ-
chanics of the constructs for molar loading were eval- ences were noted between the control group and all
uated within a 0 to 900 N range. The same mechanical other groups for yield load and stiffness. Differences
evaluation parameters and statistical analysis were were noted between the slide and straight, curved,
performed as described in the incisal loading section. and control, as well as between the inverted-L and
Second order polynomial best fit curves were created straight and curved plates for yield displacement.
to evaluate biomechanical failure. Lastly, differences were noted between the straight
and strut plates, and the slide and straight, curved,
and inverted-L for stiffness.
Results
The second order polynomial best fit curves
From among the 50 synthetic mandibles, 30 showed remarkably similar patterns of mechanical
plates, and 340 screws used in this investigation, behavior between experimental groups for both in-
some very exciting information was obtained and cisal edge and molar loading (Figs 5 and 6). For both

Table 3. STATISTICAL ANALYSIS SUMMARY USING FISHER’S PROTECTED LEAST SIGNIFICANT DIFFERENCES

Statistical
Categories Test Significance Between Groups P Value

Incisal edge loading Yield load Yes Control and all fixation techniques P ⬍ .0001
Inverted-L and Straight, Slide P ⫽ .0219, .045
Yield displacement Yes Control and Straight, Curved, Slide P ⫽ .0359, .038, .0001
Inverted-L and Straight, Curved,
Slide P ⫽ .0032, .003, .001
Straight and Slide P ⫽ .0205
Stiffness Yes Control and all fixation techniques P ⬍ .0001
Molar loading Yield load Yes Control and all fixation techniques P ⬍ .0001
Yield displacement Yes Slide and Control, Straight, Curved P ⫽ .0036, .0018,
.0001
Inverted-L and Straight, Curved P ⫽ .0394, .0036
Stiffness Yes Control and all fixation techniques P ⬍ .0001
Slide and Inverted-L, Straight, and P ⫽ .0022, .0061,
Curved ⬍ .0001
Straight and Curved P ⫽ .0262
Peterson, Haug, and Van Sickels. Evaluation of BSRO Fixation Techniques. J Oral Maxillofac Surg 2005.
1322 EVALUATION OF BSRO FIXATION TECHNIQUES

forms of loading, the control behaved in a dissimilar while the straight and curved plate systems resisted
fashion. For each experimental group, load was re- the least. This could be explained by the 2 shafts of
sisted logarithmically along a straight slope until the the slide plate providing more resistance to torsion
yield point was reached after which data recorded on than the single shaft systems. As has been reported in
the graph were discontinued. prior investigations, the positional screws in an L-
Lastly, some interesting observations were made pattern performed the best of all of the groups
regarding the fixation systems when failure was tested.11-14,22,24,26
reached. For the inverted-L positional screws, at fail- Our investigation evaluated the biomechanical be-
ure, the fixation/substrate (polyurethane mandible) havior of several rigid internal fixation techniques
interface shattered. Screws did not bend. For each of used in reconstructing BSROs. We used both a sub-
the plate fixation systems, the plates bent and de- strate that resembled natural tissue in shape, geome-
formed at their respective shafts. The slide plate re- try, and anatomic dimension, yet was synthetic. While
sisted more torsion before failure than the straight or loading at the incisal edge mimicked vertically de-
curved plates. forming forces and molar loading mimicked torsion-
ally deforming forces that are encountered under clin-
ical circumstances, they cannot completely represent
Discussion
the complex interaction between the mandible and
From among the 50 synthetic mandibles, 30 plates, musculature in function. Thus, we can only expect to
and 340 screws used in this investigation, some very identify trends in behavior that would be helpful in
exciting information was obtained, observations making decisions clinically.
made, and conclusions drawn. First, a comparison of When considering function, a review of the bite
the second order polynomial best fit curves (Figs 5 force literature shows some very surprising informa-
and 6) showed some very similar mechanical behavior tion. While this type of information has existed since
among the experimental groups. A first order polyno- 1895,35 its communication in the scientific literature
mial would take the form: x ⫽ y ⫹ z, a second order is not uniform, and for the most part relates only
would take the form x2 ⫽ y ⫹ z, a third order would information regarding healthy patients. Occlusal
take the form x3 ⫽ y ⫹ z, and so on. Thus, for a forces have been classified as swallowing, chewing,
straight line second order polynomial best fit curve, or maximum bite forces. Maximum molar bite forces
the experimental groups resisted load logarithmically have been identified from a low of 1.6 kg to a high of
in relation to the distances displaced. It was interest- 443 kg (15.7 to 4,341.4 N).36-42 Yet, this magnitude of
ing that this trend was true for both the bicortical force would not be encouraged in the postoperative
positional screw system and all of the monocortical setting. Mean molar swallowing forces have ranged
plate and screw systems, for both vertical and tor- from 1.7 to 30.2 kg (16.7 to 296.0 N).36-38 Mean molar
sional loading. Yield points (discontinuance of the chewing forces have ranges from 1.6 to 26.7 kg (15.7
line on the graph) did differ among the groups tested. to 261.7 N)36-40and are dependent upon the food
A review of the statistical comparisons (Table 3) source being chewed. Yet each of these recorded
showed differences among the experimental groups forces involved healthy individuals who have not
in their abilities to resist loads. Yet, a review of the been subjected to any surgical intervention.
loads resisted (Table 2), coupled with the patterns of Ellis et al have indicated that bite forces in the acute
behavior showed some interesting but understand- postoperative period are much less than we have
able findings. The loads resisted by the positional previously recognized both long term postoperative
screws in an L-pattern were the greatest for both and also for the non-operated population.43-45 During
molar and incisal edge loading. They resisted both an investigation assessing estimated occlusal forces
vertical and torsional forces consistently. The plate subsequent to orthognathic surgery, their group sug-
fixation groups resisted vertical loads (incisal edge gested that the molar bite force for the non-operated
loading) in a consistently poor fashion (Table 3). The male was 52.3 kg (512.5 N) and non-operated female
straight and curved systems were virtually equal with 39.0 kg (382.2 N) and of the incisal region 10.6 kg
the slide plate performing the worst. This could be (103.9 N) and 14.2 kg (139.2 N), respectively.43 Their
explained by the similarities in the lengths of the estimate immediately postoperatively for molar bite
shafts of the straight and curved plates, and more than forces was 13.3 to 19.2 kg (130.3 to 188.2 N) for
twice the length of the shaft for the slide plate. The females and 21.5 to 48.1 (210.7 to 471.38 N) for
lever arm that was created resulted in instability. The males. Incisal forces were estimated to be about one
longer the lever arm, the less stable. Molar loading quarter of that for molar loads, being 3.1 to 5.3 kg
(torsion), however, resulted in a different trend. This (30.4 to 51.9 n) for females and 4.4 to 10.0 kg (43.1 to
time, the positional screws in an inverted-L pattern 98.0 N) for males.43 In another investigation by their
and the slide plate system resisted the most torque, group examining the postoperative bite force for
PETERSON, HAUG, AND VAN SICKELS 1323

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