Name: sinni

Exercise 4: Endocrine System Physiology: Activity 3: Hormone Replacement Therapy Lab Report

Pre-lab Quiz Results

You scored 50% by answering 2 out of 4 questions correctly.

1. Follicle-stimulating hormone (FSH)

You correctly answered: d. stimulates ovarian follicle development.

2. Estrogen
You correctly answered: d. is produced by developing ovarian follicles.

3. Calcitonin
Your answer : c. stimulates osteoclast activity and inhibits calcium uptake into long bones.
Correct answer: b. works against the development of osteoporosis.

4. Which of the following statements is true?

Your answer : b. An untreated female's T score is anticipated to become more positive after menopause.
Correct answer: c. The ovaries stop secreting estrogen after menopause.

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Experiment Results
Predict Question:
Predict Question 1: What effect will the saline injections have on the control rat's vertebral bone density?
Your answer : c. The saline injections will not change the rat's vertebral bone density (indicated by an unchanging T score).

Predict Question 2: What effect will the estrogen injections have on the estrogen-treated rat's vertebral bone density?
Your answer : a. The estrogen injections will increase the rat's vertebral bone density (indicated by a less-negative T score).

Predict Question 3: What effect will the calcitonin injections have on the calcitonin-treated rat's vertebral bone density?
Your answer : c. The calcitonin injections will not change the rat's vertebral bone density (indicated by an unchanging T
score).

Experiment Data:

Rat Elapsed Days Saline injections Estrogen injections Calcitonin T score

injections
Control 7 7 0 0 -2.84
Estrogen 7 0 7 0 -1.67
Calcitonin 7 0 0 7 -2.35

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Post-lab Quiz Results
You scored 0% by answering 0 out of 4 questions correctly.

1. Saline injections were used in this experiment to measure the effect of

Your answer: a. sodium chloride on bone density.
Correct answer: c. a placebo on bone density.

2. In the ovariectomized rats used in this experiment

Your answer: a. estrogen levels were elevated because of the loss of negative feedback control.
Correct answer: d. osteoporosis was evident prior to the injections of estrogen.

3. Injection of calcitonin into an ovariectomized rat will

Your answer: a. have no effect on bone density and, therefore, should be excluded from rat hormone-replacement
therapies.
Correct answer: b. inhibit osteoclast activity and stimulate calcium uptake and deposition in long bones.

4. As the rat's bone density increases

Your answer: b. the rat requires more gaseous anesthetic to remain immobilized.
Correct answer: a. the X-ray scanning assay reports a less-negative T-score.

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Review Sheet Results
You have not completed the Review Sheet.

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