Documente Academic
Documente Profesional
Documente Cultură
engineering aspects
of space experiments
Alessandro Donati
Physical
Life Science
Science
ISS
Exploration
Equipment
• Flight software
• Electronic controls • Man-machine interface
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Mechanics/Structural/Thermal
• Mechanical design
• FEM
• Structural analysis
Biology
• Assembly and integration
• Fracture Control
• Thermal design and analysis
System
AIV
A twofold role:
http://www.bioreactorexpress.space/
Bioreactor Express is a commercial initiative that enables any potential user to directly fly
their experiment making access to the portfolio of standard and flight proven hardware
taking advantage of the longstanding experience of the Bioreactor Express industrial
consortium.
Kubik
Columbus
Kubik insert
7- Integration at
http://www.bioreactorexpress.space/ launch site
8- Transfer to ISS
9- On orbit
operations
11- Data and samples delivery 10- Return to Earth 9- Ground control
12- Scientific dissemination to science team
Examples :
SCORPI-T
LIFE
2) Not every reagent usually used in the lab can be brought onboard ISS
7) Plan well in advance and detail the logistic of the experiment, especially
the integration steps
Scientific idea
Experiment
Scientific Requirements
2) Hardware development
1) Scientific project 3) Experiment integration at launch site
4) Upload
7) Laboratory analysis
6) Download
5) Experiment execution onboard ISS, storage
L-29h to L-48 h
Paolo Nespoli
Proprietary and Confidential information: this document, and any part attached to it contains confidential and proprietary information of Kayser Italia S.r.l.. The addressee shall not disclose,
disseminate or distribute such to any person, and shall not use such information, other than pursuant to a specific agreement between the addressee and Kayser Italia S.r.l..
UHB/PI
California (SpaceX)
Kubik
o Temperature control between 6°C .. 38°C
o Centrifuge insert
o Standard Experiment Containers
o Interface plate
o Power supply to EC or I/F plate
o No commands and data
o Easy crew manual operations for EC and I/F
plate mounting and removal
Biolab
Microscope &
Spectrophotmeter
Handling Mechanism
Temperature
Controlled Units 1 / 2
Incubator with centrifuge
Biolab
o Microscope
Based on the Olympus ground
microscope BX40 and Sony CCD
camera (sensor size: 1/3”; Pixel
size: 7.4 x 7.4 m)
o Spectrometer
Based on two compact Zeiss
detector blocks based on a photo
diode array (256 diodes) from
Hamamatsu)
Biolab
o Incubator
Gravitational environment with two centrifuges (0,001g to 2 g)
Controlled thermal environment for the
incubation (+18°C to +40 °C)
Illumination and observation capabilities
Atmospheric environment through the Life
Support System
Biolab
o Temperature Controlled Units
Before and after use, Experiment Containers can be stored in two
large cooler/freezers, the TCU’s
Manually operated
Internal volumes around 20 liters each
Temperature control between -20°C .. +10°C
Biolab
o Glovebox
Air in the working volume can be controlled between 21 and 38°C +/-
2°C
No control of the humidity
A permanent slight under pressure is maintained in the working
volume has a second level of containment
Electrical interface available
Biobox / Simbox
o Temperature control between 4°C .. 37°C
o Centrifuge insert
o Standard Experiment Containers
o Interface plate
o Power supply to EC or I/F plate
o Commands and data
o Flown on
Russian satellites
Shuttle
Chinese capsule
o Compatible with ISS
range (deg C)
Temperature
on board ISS
on ground
Standard
Quantity
Quantity
2 .. 10
ESA Thermal Container 2 0 -20 .. -15
-80 .. -20
2 .. 10
Small ESA Thermal Container 2 2
-20 .. -15
-20 .. -15
Mini ESA Thermal Container 3 1
-80 .. -20
experiment
experiment
weight (Kg)
size (mm)
Max.
Max.
ESA Thermal Container 8 280 x 220 x 120 4 Biolab Experiment Containers
Experiment set of Kubik incubator
Small ESA Thermal Container 1,5 275 x 122 x 122
(32 KIC)
32 blood / urine vials packed in
Mini ESA Thermal Container 2,0 160 x 100 x 100
plastic bags or 9 KIC units
NASA MERLIN
o Temperature control between -20°C .. 48,5°C
o No Centrifuge
o No Standard Experiment Containers
o No Interface plate
o No Power supply to EC or I/F plate
o No Commands and data
o Three units available on ISS
o Easy operations and interfaces
NASA NANORACKS
o No temperature control
o Centrifuge insert
o Standard Experiment Containers
o Power supply to EC or I/F plate
o Easy operations and interfaces
NASA MELFI
o Main Cold storage facility on board ISS
o Temperature ranges presently working: -95°C; +2°C
o Samples in experiment trays
ASI BIOKON
o Multipurpose experiment container
o Allows incubation of small volumes up to 37°C
o Autonomous or external power supply
NASA COLDBAG
o Active ultra-cold container for transportation of experiments to / from ISS
o Temperatures range between +4°C and -160°C
+4°C
-26°C
-32*C
NASA GLACIER
o Active ultra-cold container for transportation of experiments to / from ISS
o Temperatures range between +4°C and -160°C
Sounding rockets
o Ballistic missile able to take payloads to altitudes of 250-750 km, with almost
vertical ascent and descent trajectories
o “Microgravity(1)” conditions are met during the freefall phase once the rocket
motors have exhausted their thrust and have dropped
o The duration of weightlessness, in the range from 6 to 13 minutes, is
determined by the apogee reached by the rocket
Free flyers
o Automatic (non-manned) satellites available for research in microgravity
Foton – Bion (Roskosmos)
Hazard Category:
o Release of materials can be catastrophic, critical or non-hazardous
o List of potentially hazardous materials submitted to NASA boards
o Level 1 toxic materials are “Critical”, Level 2 or greater are
“Catastrophic”
2 LoC 3 LoC
1 LoC
(Critical Hazard) (Catastrofic Hazard)
THL 0 1 2-3
THL:
RNA later THL = 1 2 LoC
Paraformaldehyde THL = 2 3 LoC
BSL:
Xenopus laevis (tadpoles) BSL = 1 1 LoC
Human T-lymphocytes cells BSL = 2 Moderate 2 LoC
Materials Compatibility
Test of LoC
What a mission is
Ground experiment
The typical schedule includes the arrival at launch site at L-5 days
(where L is the launch date)
EST aims to simulate the whole mission, from the preparation of the
experiment containers in the laboratory, including the transfer from the
science team’s lab, to the on-board workflows and finally the handover
to the science time after landing.
EST is the only occasion for testing the protocols and the hardware
under real-like conditions.
For experiments using the Kubik facility, the ground experiment can be
perfomed in a Kubik ground model, or by means of the Kubik Interface
Simulation Station (KISS)