Immunology and Serology Course Outline

Department of Medical Technology

Far Eastern University –Manila

COURSE DESCRIPTION: This course deals with the basic concepts of immunology and principles of serological
procedures, reading, interpretation of results and their clinical significance.

CREDITS: 4 units (3 units lecture and 1 unit laboratory)

CONTACT HOURS: 3 hours lecture; 3 hours lecture

Total of 54 lecture hours and 54 laboratory hours per semester

PLACEMENT: 3rd Year, 2nd Semester

PREREQUISITES: Biochemistry and Bacteriology

COURSE OUTCOMES:
At the end of this course, the learner will be able to:
1. explain the immune system of the body
2. apply the principles of immunology in serology and laboratory diagnosis of specific disease through the use of serological reactions
3. appreciate the importance of the course in the diagnosis and treatment of diseases
4. manifest the following values: Integrity. honesty, critical thinking, empathy and value for life

Week Topic Activity / Reference

1 Orientation Course Outline Discussion
Grading , Activities
2 LECTURE: Reference chapters:
Topic 1: Overview of Immunology Chapter 1, 3 & 4 Turgeon 5th Edition
Topic 2: Cells and Cellular Activities of the Immune and
System Supplementary chapters:
Chapter 1 & 2, Stevens 3rd Edition
LABORATORY: Reference chapters:
Topic 1 -Safety and Specimen Preparation Chapter 2 , Stevens 3rd Edition
Topic 2 – Quality Assurance and Quality Control Chapter 6 & 7 , Turgeon 3rdEdition
Lab Experiment: Glove Donning and Removal
3 LECTURE: Reference chapters:
Topic 3: Antigens and Antibodies Chapter: 2, Turgeon 5th Edition

Supplementary chapters:
Chapter 3 & 4, Stevens 3rd edition
LABORATORY:
Lab Experiment: In-Vitro Phagocytosis
SHIFTING EXAMINATION 1 (Topic 1 &2)
5 LECTURE: Reference chapters:
Topic 4: Soluble Mediators of the Immune System Chapter 5, Turgeon 5th Edition

Supplementary:
Chapter 5 , Stevens 3rd Edition
Chapter 6 , Stevens 3rd Edition
LABORATORY: Reference chapters:
Topic 4: Major Histocompatibility complex Chapter: 2, Turgeon 5th Edition

Supplementary chapters:
Chapter 3 & 4, Stevens 3rd edition
5 LECTURE: Reference chapters:
Topic 5 : Hypersensitivity Chapter 26, Turgeon 5th Edition

Supplementary chapters:
Chapter 13, Stevens 3rd Edition
LABORATORY:
Lab - Ethical Handling of Animals in
 Research
SHIFTING EXAMINATION 2 (Topic 3, 4 & 5)
6 PRELIMINARY EXAMINATION
7 LECTURE: Reference:
Topic 6: Precipitation Methods Chapter 8, Stevens 3rd Edition
Topic 7: Agglutination Methods Chapter 10, Turgeon 5th Edition

Supplementary:
Chapter 9, Stevens 3rd Edition
LABORATORY: Reference:
Basic Serologic Techniques Chapter 8, Turgeon 5th Edition
Lab - Point of Care Testing Chapter 9, Turgeon 5th Edition
Lab Experiment: Pregnancy Test (HCG

8 LECTURE: Reference:
Topic 8: Labeling Techniques in Immunoassay Chapter 12, Turgeon 5th Edition
Topic 9: HIV
Supplementary:
Chapter 10, Stevens 3rd Edition
LABORATORY: Chapter 25, Turgeon 5th Edition
Lab Experiment: HIV Test Kit Chapter 23, Stevens 3rd Edition

SHIFTING 1 (Topic 7 & 8)

9 LECTURE: Reference:
Topic 10.1: Toxoplasmosis Chapter 20 , 21, 22, 23, 24 , Turgeon 5 th Edition
Topic 10.2: Cytomegalovirus
Topic 10.3: Infectious Mononucleosis Supplementary:
Topic 10.4: Viral Hepatitis Chapter 22, Stevens 3rd edition
Topic 10.5: Rubella Infection

LABORATORY:
Lab Experiment: Slide Agglutination
(ABO Typing Direct and Reverse)
Lab Experiment: Hepatitis B Test Kits
SHIFTING 2 (Topic 9 ,10 & 11.1 to 11.5)
10 LECTURE:
Reinforcement of previous topics
LABORATORY: Chapter 16, Turgeon 5th Edition
Lab – Introduction to Vaccination

11 MIDTERM EXAMINATION

12 LECTURE: References:
Topic 11.1: Streptococcal Infections Chapter 17, Turgeon 5th Edition
Topic 11.2: Syphilis Chapter 18, Turgeon 5th Edition
Topic 11.3: Vector Borne Diseases Chapter 19, Turgeon 5th Edition

Supplementary:
Chapter 19 & 21 , Stevens 3rd Edition
LABORATORY:
Lab Output: RPR
13 LECTURE: References:
Topic 12: Immunoproliferative Disorders Chapter 27 , 28, 29 & 30, Turgeon 5 th Edition
Topic 13.1: Autoimmune Disorders
Topic 13.2: SLE Supplementary:
Topic 13.3: Rheumatoid Arthritis Chapter 14 & 15 , Stevens 3rd Edition

LABORATORY
Lab Output: CRP
Shifting Examination1 (Topic 12.1 to 12.3)
14 LECTURE: References:
Topic 14: Solid Organ Transplantation Chapter 31 , Turgeon 5th Edition

Supplementary:
Chapter 17, Stevens 3rd Edition
LABORATORY: RF
15 LECTURE: References:
Topic 15: Bone Marrow Transplantation Chapter 32, Turgeon 5th Edition

Shifting Examination1 (Topic 15 & 16)

16 LECTURE: References:
Topic: Tumor Immunology Chapter 22, Turgeon 5th Edition

Supplementary:
Chapter 18, Stevens 3rd Edition
LABORATORY: ANA Test Kits
17 REINFORCEMENT of previous topics / Case Presentation /
Journal Critique
18 FINAL EXAMINATION
DEPARTMENTAL EXAMINATION

D. Required Reading (Textbook)

2014 Turgeon, Mary Louise, Immunology and Serology in Laboratory Medicine, 5th Edition, Mosby-Year Book,

Suggested Readings:
Stevens, Christine Dorresteyn. Clinical immunology & serology : a laboratory perspective. Philadelphia : F.A. Davis, c2010.
NS 52428 Cir RB 46.5 S74 2010
Roitt, Ivan., Essential Immunology, 11th Edition, F.A. Davis
Bryant, Neville J., Laboratory Immunology and Serology, 3rd Edition, W.B. Saunders Company
Laboratory Manual In Immunology and Serology
Abbas, Abul K. Cellular and molecular immunology. Philadelphia, PA : Elsevier/Saunders, 2015.
IAS 0927 Cir QR 185.5 A2 2015
Abbas, Abul K., Basic immunology : functions and disorders of the immune system. Philadelphia, PA : Elsevier/Saunders, 2014.
IAS 0924 Cir QP 181 A2 2014
Delves, Peter J. Roitt's essential immunology. Chichester, West Sussex : Wiley-Blackwell, c2011.
IN 0061 Cir QR 181 R6 2011

E. Course Requirements
Attendance in Class
- - The students are allowed but only 20% of the total number of hours in a semester for absences.
Major Examinations, Quizzes, recitations, assignments and reaction papers
Assignments: Concept Maps, Diagrams, Differential Diagnosis Diagrams and Concept Maps, Written Summary.

F. Grading System
Prelim, Midterm and Finals Requirements:
Lecture (60%)
Recitation 5% (At least 2 per term)
Assignment 5% (At least 2 per term)
Shifting Exam 20% (60 items per term)
Quizzes 30% (15 items, no bonus, minimum of 5 quizzes per term)
Lecture Exam 40% (Standardized departmental exam)
100%

Laboratory (40%)

Quizzes 35% (15 items, no bonus, minimum of 5 quizzes per term)

Practical Exam 30%
Written Exam 30%
Worksheet 5%
100%

FINAL RATING: Average of 3 concepts grades x 80% + Departmental Exam 20%= 100% (Course Grade)

G. Classroom Policies
FEU Academic Integrity Policy

Prepared by:

Mary Rose F. Lirio, RMT, MSMT

Subject Adviser, 1st semester S.Y. 2019-2020

Approved by:

Mr. Franscisco Gellecanao, RMT, MPH

Program Head
Department of Medical Technology