Human Physiology Questions and Answers – Blood Clotting & Coagulation

This set of Human Physiology Multiple Choice Questions & Answers (MCQs)
focuses on “Blood Clotting & Coagulation”.

1. Tissue plasmin activator _______________

a) helps in wound healing

b) allergy response

c) immunity

d) dissolves clot in blood vessels

View Answer

Answer: d

Explanation: Plasmin is an important enzyme present in blood that degrades fibrin

clot. Plasmin protein is encoded by the PLG gene.

2. Which of the following will not coagulate when placed separately on four
slides?

a) Blood serum

b) Blood plasma

c) Blood from pulmonary vein

d) Blood from lymphatic tissue

View Answer

Answer: a
Explanation: Blood serum is a component that is neither a blood cell nor a clotting
factor. It is the blood plasma not including the fibrinogens.

3. The vitamin essential for blood clotting is _______

a) vitamin A

b) vitamin B

c) vitamin C

d) vitamin K

View Answer

Answer: d

Explanation: Vitamin K is an essential nutrient necessary for responding to

injuries. It regulates normal blood clotting. It also helps for bone health.

4. What prevents clotting of blood in blood vessels?

a) Serotonin

b) Fibrinogen

c) Heparin

d) Fibrin

View Answer

Answer: c

Explanation: Heparin is used as an anticoagulant. It inhibits reactions that lead to

the clotting of blood and the formation of fibrin clots both in vitro and in vivo.

5. Clumping of cells in known as _______

a) clotting

b) mutation

c) agglutination

d) glutathione

View Answer

Answer: c

Explanation: Agglutination is a process that occurs if an antigen is mixed with its

corresponding antibody called isoagglutinin. This is used during blood grouping.

6. Which of the following is correct?

a) Lymph= Plasma + WBC’s +RBC’s

b) Plasma= Blood – Lymphocytes

c) Neuron= Cyton+ Dendron+ Axon+ Synapse

d) Blood= Plasma+ RBC’s + WBC’s + Platelets

View Answer

Answer: d

Explanation: Blood is essential for life. Blood consists of plasma, rbcs, wbcs, and
platelets.

7. Antibiotics are useful against __________

a) virus

b) bacteria
c) autoimmune disease

d) fungi

View Answer

Answer: b

Explanation: Antibiotics are strong medicines that treat bacterial infections.

Antibiotics won’t treat viral infections because they can’t kill viruses.

8. Antigen presenting cells are _______

a) T cells

b) B cells

c) Macrophages

d) Mast cells

View Answer

Answer: a

Explanation: T cells are a type of lymphocyte that lays central role in cell mediated
immunity. It has presence of receptor on the cell surface.

9. Which of the following plasma protein is involved in coagulation of blood?

a) Albumin

b) Globulin

c) Fibrinogen

d) Amylase
View Answer

Answer: c

Explanation: Fibrinogen is a glycoprotein, during tissue injury it is converted by

thrombin to fibrin and subsequently to a fibrin based blood clot.

10. In the clotting mechanism pathway, thrombin activates factors ___________

a) XI VIII V

b) XI IX X

c) VIII X V

d) IX VIII X

View Answer

Answer: a

Explanation: Thrombin is encoded by F2 gene. There are 12 clotting factors.

Thrombin activates XI, VIII and V factors.