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ALPHORES e TECHNO A/C COLLEGE

VAVILALAPALLY, KARIMNAGAR.

NEET / JEE / EAMCET


Date :25-09-2019 TEST ID: 397
Time : 00:17:00Mins BIOLOGY
Marks : 68
8.HUMAN HEALTH AND DISEASE

Single Correct Answer Type

46. Which one of the following is not the property of cancerous cells?
1) They do not require extracellular growth factors 2) They do not remain confined in the area of
formation
3) They show contact inhibition 4) They divide in an uncontrolled manner
47. Which of the following property is possessed by cancerous cell?
1) A new blood vessels 2) Uncontrolled cell 3) Both (a) and (b) 4) Controlled cell division
formation division
48. Physical carcinogen, 𝑒. 𝑔., UV-ray, X-ray and γ-rays causes
1) DNA damage 2) RNA damage
3) Both (a) and (b) 4) Protein damage
49. Which one of the following techniques is used for the detection of cancers?
1) Magnetic Resonance 2) Radiography (X-ray) 3) Computed Tomography 4) All of the above
Imaging (MRI) (CT)
50. Tumour viruses or cancer causing viruses called …A… have …B… . Here A and B refers to
1) A-oncogenic bacteria; B-bacterial oncogenes
2) A-oncogenic viruses, B-viral oncogenes
3) A-oncogenic protozoan; B-protozoan oncogenes
4) None of the above
51. Alpha-interferons
1) Activate the immune system
2) Help in destroying the tumour
3) Both (a) and (b)
4) None of the above
52. Malignant tumours are
I. mass of neoplastic cells
II. cells that grow very rapidly and damaging the surrounding normal tissue
III. cells that show the property of metastisis
Which of the statements given above are correct?
1) I and II 2) I and III 3) II and III 4) All of these
53. Normal cell have genes called …A… which are present in inactiveated state but under certain conditions
like …B… they get transformed to …C… Here A, B and C refers to
1) A-cellular oncogenes, B-mutation, C-cancer causing oncogenes
2) A-proto-oncogenes, B-mutation, C-disease causing genes
3) A-viral oncogenes, B-mutation, C-tomour causing genes
4) None of the above
54. Consider the following statements
I. The property of metastasis is shown by malignant tumours
II. Carcinogens are the agents that causes cancer
III. Benign tumour causes little damage to body cells
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Which of the statements given above are correct?
1) I and II 2) I and III 3) II and III 4) I, II and III
55. Electrocardiograph was developed by
1) Hans Berger 2) Willem Kolff 3) Willen Einthoven 4) Wilhelm Roentgen
56. To confirm ELISA for AIDS, we used
1) Western blotting 2) Northern blotting 3) Southern blotting 4) Eastern blotting
57. MRI is not allowed in the following conditions except one. Identify the exception
1) Presence of pace-maker in the body
2) Pregnant women
3) Person suffering from stroke
4) Presence of metallic plate in the body from treatment of broken bones
58. Tiny lesions of multiple sclerosis on brain and spinal tissue can be observed by
1) Magnetic resonance imaging 2) Position emission tomography
3) X-rays radiography 4) Digital subtraction angiography
59. In a standard ECG, which one of the following alphabets is the correct representation of the respective
activity of human heart?
1) R-repolarization of ventricles 2) S-start of systole
3) T-end of diastole 4) P-depolarization of the artia
60. Consider the following statements about biomedical technologies.
I. During open heart surgery, blood is circulated in the heart-lung machine.
II. Blockage in coronary arteries is removed by angiography.
III. Computerised Axial Tomography (CAT) shows detailed internal structure as seen in a section of body.
IV. X-ray provides clear and detailed images of organs like prostate glands and lungs.
Which two of the above statements are correct?
1) II and IV 2) III and IV 3) I and III 4) I and II
61. An example of gene therapy is
1) Production of injectable hepatitis-B vaccine
2) Production of vaccines in food crops like potatoes which can be eaten
3) Introduction of gene for adenosine deaminase in persons suffering from Severe Combined Immuno
Deficiency(SCID)
4) Production of test tube babies by artificial insemination and implantation of fertilized eggs

Matrix-Match Type

This section contain(s) 1 question(s). Each question contains Statements given in 2 columns which have to be
matched. Statements (A, B, C, D) in columns I have to be matched with Statements (p, q, r, s) in columns II.

62. Match the following columns

Column-I Column- II

(A) Chemical cancer causing agent (1) Carcinogens

(B) Physical cancer causing agent (2) Cigarette smoke

(C) Biological cancer causing agent (3) X-rays

(D) Cancer causing agent (4) Oncogenic viruses

CODES :

A B C D

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1) 2 3 4 1

2) 3 1 4 2

3) 1 4 2 3

4) 4 2 3 1

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ALPHORES e TECHNO A/C COLLEGE
VAVILALAPALLY, KARIMNAGAR.

NEET / JEE / EAMCET


Date :25-09-2019 TEST ID: 397
Time : 00:17:00Mins BIOLOGY
Marks : 68
8.HUMAN HEALTH AND DISEASE

: ANSWER KEY :
46) 3 47) 2 48) 1 57) 1 58) 1 59) 4 60) 3
49) 4 50) 2 51) 3 52) 4 61) 3 46) 1
53) 1 54) 4 55) 3 56) 1

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ALPHORES e TECHNO A/C COLLEGE
VAVILALAPALLY, KARIMNAGAR.

NEET / JEE / EAMCET


Date :25-09-2019 TEST ID: 397
Time : 00:17:00Mins BIOLOGY
Marks : 68
8.HUMAN HEALTH AND DISEASE

: HINTS AND SOLUTIONS :


46 (3) sloughed from such tumours reach distant sites
Normal cells shows the property of contact through blood, and wherever they get lodged in
inhibition. Normal somatic cells when grown in the body, they start a new tumour there. This
culture becomes growth inhibited when they property called metastasis is the most feared
encounter another cell. Cancerous cells lost the property of malignant tumours
property of contact inhibition 53 (1)
47 (2) Normal cell have genes called cellular oncogenes,
The uncontrolled division or proliferation of cells which are present in inactivated state but under
without any differentiation is called cancer certain conditions like mutation they get
48 (1) transformed to cancer causing oncogenes
Transformation of normal cells into cancerous 54 (4)
neoplastic cells may be induced by physical, Malignant Tumour is a cancerous Tumour. It
chemical or biological agents. These agents are shows metastasis and thus invades other body
called carcinogens. Ionizing radiations like X-rays parts
and gamma rays and non-ionizing radiations like The cancer causing agents are called carcinogens,
UV rays causes DNA damage leading to neoplastic 𝑒. 𝑔., Chemical agents – Aniline dyes
transformation Physical agents – X-rays, Y-rays, UV-rays
49 (4) Biological agents – Oncogenic viruses
Techniques like radiography (Use of X-rays). Benign tumour is non-cancerous tumour. It is less
CT (Computed Tomography) and MRI (Magnetic fatal to the body
Resonance Imaging) are very useful to detect 55 (3)
cancers of the internal organs Magnetic Resonance Imaging (MRI) technique
50 (2) was developed by Felix Block and Edward M
Tumour viruses or cancer causing viruses called Purcell. This technique relies on the Nuclear
oncogenic viruses, have viral oncogenes Magnetic Resonance (NMR). MRI detects water
51 (3) because it focuses on the behaviour of hydrogen
Tumour cells have been shown to avoid detection atoms in water molecule. It is especially useful in
and destruction by immune system. Therefore the studying brain and spinal cord. Scapula and
patients are given substances called biological canine are osteocytic structures with negligible
response modifiers such as α-interferon, which water content so, they do not appear in MRI
activates their immune system and helps in 56 (1)
destroying the tumours HIV is a causative agent of disease AIDS. ELISA
52 (4) (Enzyme Linked Immune Sorbent Assay) is used
The malignant tumours, is a mass of proliferating to test HIV infections. Western blottest is widely
cells called neoplastic or tumour cells. These cells used confirmatory test for HIV infection.
grow very rapidly, invading and damaging the 58 (1)
surrounding normal tissues. As these cells Magnetic Resonance Imaging (MRI) is a non-
actively divide and grow, they also starve the invasive technique, capable to map internal
normal cells by competing for vital nutrients. Cells tissues, highlight pathological changes and study

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tissue metabolism with the help of spectroscopy. is called gene therapy, for example, introduction
This technique is largely used to observe the tiny of gene for adenosine deaminase in person
lesions of multiple sclerosis on brain and spinal suffering from Severe Combined Immuno-
tissue. deficiency (SCID).
59 (4) 62 (1)
In ECG, P-wave indicates impulse of contraction Chemical cancer causing agent – Cigarette smoke
generated by SA-node and it spreads in atria Physical cancer causing agent – X-rays, gamma
causing atrialdepolarisation. T-wave is the most rays
constant and conspicuous wave having the tallest Biological cancer causing agent – Oncogenic virus
amplitude. It is the first positive deflection during Cancer causing agent – Carcinogens
ventricular depolarization.
S-wave is the next downward deflection constant
but often inconspicuous.
T-wave is repolarization wave of ventricular
relaxtion.
60 (3)
Concern to biomedical technologies, the given
statements I and III are correct.
61 (3)
The treatment of inherited diseases by
introducing wild type copies of the defective gene

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