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PHYSICAL
AND
CHEMICAL INCOMPATIBILITY
BY
A) Physical incompatibility
B) Chemical incompatibility
C) Therapeutic incompatibility
K.SAMINATHAN. M.pharm, M.B.A,( P
A) PHYSICAL INCOMPATIBILITY:
Example:
INTENTIONAL:
When the prescriber knowingly prescribes the
incompatibility drugs.
UNINTENTIONAL:
When the prescriber prescribes the drugs
without knowing that there is incompatibility
between the prescribed drugs.
METHOD (A):
The method is followed when diffusible precipitates are
formed in very small quantity. Divide the vehicle into two equal
portions. Dissolve one of the reacting substances in one of the
portion and the other in the other portion. Mix the two portions by
slowly adding one portion to the other by rapid stirring.
K.SAMINATHAN. M.pharm, M.B.A,( P
METHOD (B)