Revised National TB Control Programme (RNTCP)Common

Question
Doses in RNTCP Daily Regimen (Starting Dt.02-10-2017)
Type of TB Case Doses in IP Doses in CP#
New 56 doses (8 weeks x 7 112 doses(16 weeks x 7
days/week) or 28*2 days/week) or 28*4
Previously treated 84 doses (12 weeks x 7 140 doses(20 weeks x 7
days/week) or 28*3 days/week) or 28*5

Inj. Streptomycin
• 15 mg/kg (12–18 mg/kg) daily
• Maximum daily dose 1000 mg
• Patients aged over 50 years may not be able to tolerate more than 750
mg daily
• Similarly, patients weighing less than 50 kg may not tolerate doses above
500-750 mg daily
Daily Dose Schedule for Adults
(as per weight bands)
Weight band Number of tablets Inj.
Streptomycin

Intensive phase Continuation phase

HRZE HRE

75/150/400/275 mg 75/150/275 mg gm

25-39 kg 2 2 0.5 gm

40-54 kg 3 3 0.75 gm

55-69 kg 4 4 1 gm

≥70 5 5 1 gm

Drug Dosage for Paediatric TB

Weight Number of tablets Inj.
category Streptomycin
(dispersible FDCs)

Intensive phase Continuation phase

HRZ E HR E

50/75/150 100 50/75 100 mg

4-7 kg 1 1 1 1 100

8-11 kg 2 2 2 2 150

12-15 kg 3 3 3 3 200

16-24 kg 4 4 4 4 300

25-29 kg 3 + 1A* 3 3+1A* 3 400

30-39 kg 2 + 2A* 2 2+2A* 2 500

 Shorter Regimen (9 to 11 Months) R--R, H—S (Starting 07-04-2018)

I.P.= 4 to 6 Months C.P. = 5 Months

Mfx High Dose Mfx High Dose
Kenamicine Ethionamide
Ethionamide Clofazimine
Clofazimine INH High Dose
INH High Dose Pyrazinamide
Pyrazinamide Ethambutol
Ethambutol Pyridoxine
Pyridoxine
KEM CHE PANKAJ
Kenamicine=K , Ethambutol=E, Moxifloxacin=M, Clofazimine=C, Isoniazid=H
Ethionamide=E, Pyrazinamide=P
Conventional MDR TB Regimen (24 to 27 Months)R—R/MDR TB

I.P.= 6 to 9 Months C.P.= 18 Months

LFX (Levofloxacine) LFX (Levofloxacine)
Km (Kenamicine) Eto (Ethionamide)
Cs (Cycloserene) Cs (Cycloserene)
Eto (Ethionamide) E (Ethambutol)
E (Ethambutol) Pyridoxine
Pyridoxine
Pyrazinamide
Regimen for XDR – TB without New DrugXDR
(Resistance to both FQ & SLI Class)
I.P.= 6 to 12 Months C.P.= 18 Months
Mfx (Moxifloxacine) Mfx (Moxifloxacine)
Lzd (Linezolid) Eto (Ethionamide)
Cm Inj. (Capromicine) Cs (Cycloserene)
Eto (Ethionamide) Lzd (Linezolid)
Cs (Cycloserene) Cfz (Clofazimine)
Z (Pyrazinamide) E (Ethambutol)
Cfz (Clofazimine)
E (Ethambutol)
BDQ
0-2 Week 4 Tab/Day
3-24 Week 2 Tab Thrice a week
Total Tab: 188
Total Duration of BDQ: 6 Months
 NAME DESCRIPTION
ARTI ANNUAL RISK OF TUBERCULOSIS INFECTION
ARTI OF GUJARAT -1.5
216 CASES /LAC POUPULATION/YEAR
FOR 90% DETECTION
194CASES /LAC /YEAR
SUSPECT EXAMINATION RATE TB SUSPECTS EXAMINED IN DMC IN QUARTER X 100000
TOTAL POPULATION
DISTRICT TARGET IS 260/QUARTER /LAC
MC MICROBIOLOGICALY CONFIRMED- ANY PATIENT WHO IS SMEAR
POSITIVE FOR TB OR MTB DETECTED OR CULTURE POSITIVE IS
CALLED NMC
CD CLINICALLY DIAGNOSED – ANY PATIENT WHO IS NOT MC AND
WHOSE BASIS OF DIAGNOSIS OF TB ON X RAY, BIPOSY, MRI , CT
SCAN OR CLINICALL JUDGMENT IS CD
ACSM ADVOCASSY ,COMMUNICATION AND SOCIAL MOBILISATION FOR
IEC
RETREATMENT ANY PATIENT WHO IS PREVIOUSLY COMPLETED ANTI TB
TREATMENT AND AGAIN MICROBIOLOGICALLY CONFIRMED IS
CALL RETREATMENT
TALTFU TREATMENT AFTER LOST TO FOLLOW UP- ANY PATIENT WHO HAD
TAKEN AKT FOR 1 MONTH OR MORE AND INTEURRUPTED
TREATMENT FOR 2 COSECUTIVE MNTH AND AGAIN
MICROBIOLOGICALLY CONFIRMED IS CALLED –TALTFU
OTHER ANY PATIENT WHO HAS PREVIOUSLLY TAKEN AKT BUT NOT
MICROBIOLOGICALLY CONFIRMED AND HAS TO START AGAIN AKT
CALL ED OTHER
OUTCOME CURE ANY PT WHO WAS INITIALLY
MICROBIOLOGICALLY CONFIRMED AND
COMPLETED FULL CORSE OF AKT AND HIS LAST
FOLLOW UP COMES NEGATIVE IS CALLED
CURED
T.C. ANY PT WHO IS INITIALLY NOT MC OR
CLINICALL DIAGNOSED AND HAS COMPLETED
FULL COARSE AND LAST FOLOW UP NEGATIVE
OR NOT APPLICABLE IS CALLED T.C.

FAILURE ANY PATIENT WHO IS ON AKT AND HIS LAST

FOLLOW UP IS POSITIVE IS CALLED FAILURE

SWITHCED ANY PT WHO IS DURING COARSE OF

TO SECOND TREATMENT COMES WITH REPORT OF
LINE RESISTANT TO FIRST LINE DRUGS AND HAVE
TO START SECOND LINE RGIMEN
DEFAULT- ANY PATIENT WHO IS INTURRPED TREATMENT
FOR CONSECUTIVE ONE MONTH OR MORE
 DIED ANY PT DIED DURING COARSE OF TREATMENT
IREGARDLESS OF CAUSE
TB NOTIFICATION FROM 07-05-2012 GOVT OF INDIA HAD DECLARED TB IS
NOTIFABLE DISEASE UNDER WHICH EVERY PT HAS TO BE
NOTIFIED BY PRIVATE SECTOR WHO IS ON AKT
NIKSHAY ITS WEB BASED PORTAL OF ENTRY OF TB PATIENT DETAIL AND
REST OF INDICATORS . FROM 1 ST JANUARY EVERY PATIENT IN
PUBLIC SECOTR IS NOTIFIED IN NOTIFICATION REGISTER AS WELL
AS IN NIKSHAY IN NEW LAB MODULE
99 DOTS FROM 1 ST JAN 2017 EVERY TB HIV PT IS PUT ON DAILY REGIMEN
ACCORDING TO HIS CATEGORY I/II , TREATMENT IS ENROLLED
FROM ART CENTRE WITH ART AND REGISTRED IN 99 DOTS WEB
SITE IN WHICH PT HAS TO TAKE DAILY TREATMENT AND CALL ON
TALL FREE NUMBER AFTER CONSUMING EACH DOSE AND WHICH
WILL REFLECT ON WEB SITE WITH GREEN OR RED COLOUR . AND
DAILY SMS SENT TO HIS CONCERN DOT PROVIDER
PMDT PROGRAMATIC MANAGEMENT OF DRUG RESISTANT TB
INCLUDES MONO H
CAT IV
CAT V
DST GUIDED
BDQ REGIMEN
MDR SUSPECT CRITERIA 1) CATI/II FAILURE
2) MDR CONTACT WHO IS DIAGNOSED PULMONARY TB
3) CAT DIAGNOSIS POSITIVE
4) ANY FOLLOW UP POSITIVE
THESE SAMPLES SENT TO IRL FOR LPA
CAT II OTHER PULMONARY
PLHIV
PEADIATRIC KEY POPULATION
EP CLEAR FLUID
SAMPLES SENT TO NADIAD FOR CBNAAT
MDR ANY MDR SUSPECT WHOSE SAMPLE SNT TO ACCRICATED LAB AND
HIS CULTUE IS POSITVE AND IN DST RESULT SHOWS RESITANT TO
H AND R BOTH WITH OR WITHOUT RESISTANT TO OTHER ANTITB
DRUG
XDR MDR CONFIRMED PT WHOSE SECOND LINE DST AT ACCRICATED
LAB SHOWS RESISTANT TO ONE OF FLOROQUINOLONE AND
SECOND INJECTABLE AMINOGLYCOSIDE

CAT I NEW MICRO CONFIRMED

NEW CLD
NEW EP
6 MNTH TREATMENT RED BOX , 2 MNTH IP AND 4 MNTH CP
CAT II RETREATMENT
TALTFU
FAILURE
OTHER
8 MNTH TREATMENT ,BLUE BOX ,3 MNTH IP AND 5 MNTH CP

ASHA HONORIUM CAT –I -RS. 1000/-

 CAT- II RS. 1500/-
CAT- IV , RS. 2000 –IP, CP – 3000
CBNAAT CARTRIGE BASED NUCLIC ACID AMPLIFICATION TEST
2 HRS RESULT
MTB DETECTED/NOT DETECTED
RIF DETECTED/NOT DETECTED/INDETRMINANT
LPA LINE PROBE ASSAY
DNA BASED TEST
RESULT IN 3-4 DAYS
DONE AT IRL AHMEDABAD AND JAMNAGAR COLLAGE
RESULTS – H AND R SENSITIVE OR RESISTANT
LIQUID CULTURE FOR FOLLOW UP OF MDR/XDR PATIENTS
RESULTS POSITIVE/NEGATIVE
COMES WITHIN ONE AND HALF MONTH
LJ MEDIA LOWENSTEIN JENSON MEDIA
2 MNTHS FOR CULTURE REPORT
AND AN OTHER 2 MONTHS FOR DST RESULT AFTER CULTURE
POSITIVE