Documente Academic
Documente Profesional
Documente Cultură
WORKING EXPERIENCE
Oct 2015 – present Research Assistant Professor
Department of Surgery, The University of Hong Kong, Hong Kong
Assess genetic screening of medically actionable genetic variants using
genome sequencing
Evaluate clinical utility of expanded carrier screening and newborn
genetic testing of metabolic disorders by genome sequencing
Analyze genetic and genomic data to detect rare variants causal to or
associated with rare congenital disorders, including colonic
aganglionosis
Supervise postgraduate students on bioinformatics tools development
Oct 2012 – Oct 2015 Postdoctoral Fellow
Department of Psychiatry, The University of Hong Kong, Hong Kong
Conduct research on genetic risk prediction using polygenic risk score
Detect lipid-associated variants in relation to coronary artery disease
Sep 2010 – Sep 2012 Research Officer
Genetic Epidemiology, Queensland Institute of Medical Research, Australia
Conduct research on asthma genetics
Develop bioinformatics and genetic analysis tools
Jan – July 2010 Research Assistant
Department of Surgery, The University of Hong Kong, Hong Kong
Analyze genetic data to detect copy number variants associated with
rare congenital disorders
Sep – Dec 2006 Research Assistant
Department of Medicine, The University of Hong Kong, Hong Kong
Perform cell culture and epigenetic assays
EDUCATION
- The University of Hong Kong, Hong Kong
Apr 2010 Ph.D. Statistical genetics
Aug 2006 M.Phil. Bioinformatics
Aug 2004 B.Sc. in Bioinformatics (First Class Honors, Dean’s List)
Project Title Project Code Funding Source Amount (HK$) Funding year
PUBLICATIONS
35 conference papers (7 presented orally)
43 publications (17 as first author, 1 as corresponding author)
Google Scholar Scopus (ID: 35764635500)
H-index 20 16
Number of citations 1488 1027
No. Publication IF C
4 Lu X, Peloso GM, Liu DJ, Wu Y, Zhang H, Zhou W, Li J, Tang CS et al, (2017) 27.13 23
Exome chip meta-analysis identifies novel loci and East Asian-specific coding
variants contributing to lipid levels and coronary artery disease. Nat Genet,
49(12):1722.
5 Tang CS†, Zhang H†, Cheung CYY†, Xu M† et al. (2015) Exome-wide association 12.35 29
analysis reveals novel coding sequence variants associated with lipid traits in
Chinese. Nat Commun, 6:10206.
6 Tang CS and Ferreira MAR (2012) A gene-based test of association using canonical 5.48 55
correlation analysis. Bioinformatics, 28(6):845-50.
7 Garcia-Barceló MM†, Tang CS† et al. (2009) Genome-wide association study 9.50 145
identifies NRG1 as a susceptibility locus for Hirschsprung's disease. Proc Natl Acad
Sci U S A, 106(8): 2694-9.
PRESS CONFERENCE
Presentation on “HKU and international collaborative research teams discover novel genetic markers
for blood lipids and coronary artery disease” (Nov 2017)
Presentation on “HKU leads the first Chinese exome-wide genetic study on blood lipids and coronary
artery disease” (Dec 2015)
Presentation on “HKU scientists discover that DNA changes in the Neuregulin-1 (NRG1) gene
increase the risk of Hirschsprung Disease” (March 2009)
Online Application Number: C3254747
REFENERCE
Pak C Sham, M.D., Ph.D. Maria- Mercedes Garcia-Barceló, Ph.D.
Director Associate Professor
Centre for Genomic Sciences, Department of Surgery,
6/F HKJCBIR, 1/F HKJCBIR,
The University of Hong Kong, The University of Hong Kong,
5 Sassoon Road, Pokfulam. 5 Sassoon Road, Pokfulam,
Office: (852) 2255 4486 Office: (852) 2831 5073
Fax: (852) 2855 1345 Fax: (852) 2819 9621
Email: pcsham@hkucc.hku.hk Email: mmgarcia@hkucc.hku.hk