Drug Dose Rate Indications Cautions

Dogs Cats
Ceftriaxone 15 to 50 mg/kg 25 to 50 mg/kg RTI, UTI, Loop diuretics
Dermatological (nephrotoxicity),
infections, Bacterial Bacteriostatic antibiotics
septicemia, Bone and
joint infections, Intra-
abdominal infections,
Meningitis
Cephalexin 22 to 30 mg/kg 22 to 30 mg/kg Skin infections, wound, Bacteriostatic antibiotics
bone infections,
pneumonia, UTI
Cefpodoxime 10 mg/kg 10 mg/kg Skin infections, wound, Bacteriostatic antibiotics
bone infections,
pneumonia, UTI
Enrofloxacin 5 to 20 mg/kg 5 mg/kg Skin infections, wound, Young animals, Cats
pneumonia, UTI (sometimes blindness),
Bacteriostatic antibiotics
Clindamycin 22 mg/kg 22 mg/kg Skin infection, Wound Liver disease, Renal
infection, dental diseases, Atopic Dermatitis
infection,
Doxycycline 5 to 10 mg/kg 5 to 10 mg/kg RTI, Tick-borne Animals younger than
infection, leptospirosis, seven months of age, not
with calcium or calcium-
containing medications
Ampicillin 11 to 22 mg/kg 11 to 22 mg/kg Wounds, skin  Beta-lactams (anaphylactic
infections, tooth reaction), renal impairment
abscesses and bladder
infections.
Amoxicillin 10 to 25 mg/kg 10 to 25 mg/kg Wounds, skin Beta-lactams (anaphylactic
infections, tooth reaction)
abscesses and bladder
infections.
Metronidazole 10 to 60 mg/kg 10 to 60 mg/kg Giardia, Trichomonas Liver disease, Other drugs
and Balantidium coli. (phenobarbital and
cimetidine)
Ketoconazole 10 to 15 mg/kg 5 to 10 mg/kg Blastomycosis, Liver disease, pregnant
histoplasmosis, yeast animal, may interact with
infections (Malassezia) antacids,
and dermatophyte methylprednisolone,
infections anticonvulsants, heart
medications, cyclosporine
and theophylline.
Fluconazole 5 to 10 mg/kg 10 mg/kg Dermatophytes, May interact with
blastomycosis and cimetidine, amphotericin
cryptococcosis. B, corticosteroids, certain
diuretics, fentanyl,
theophylline, warfarin,
cyclosporine
Carprofen 4.4 mg/kg 4 mg/kg Pain, inflammation, Cats (sensitive), may
chronic arthritis, interact with
postoperative pain corticosteroids, Vomiting
Meloxicam 0.2 mg/kg 0.2 mg/kg Pain, inflammation, Vomiting, dehydration,
chronic arthritis, low blood pressure, pups
postoperative pain (< 6 weeks), heart failure,
liver disease, kidney
 disease, ACE-inhibitors
Prochlorperazine 0.1 to 0.5 mg/kg 0.1 to 0.5 mg/kg Nausea and vomiting Avoided in glaucoma, low
blood pressure or shock
Ondansetron 0.1 to 1.0 mg/kg 0.22 mg/kg Nausea and vomiting Rifampin (decreases
(cancer therapy), sleep- plasma level)
apnea in bulldogs
Ranitidine 0.5 to 2 mg/kg 3.5 mg//kg Stomach and intestinal Avoided in liver or kidney
ulcers disease.
Pantoprazole 0.7 to 1 mg/kg 0.7 to 1 mg/kg Stomach ulcers May interact with
ketoconazole, iron,
thyroid supplement
Metoclopramide 0.2 to 0.5 mg/kg 0.2 to 0.5 mg/kg Vomiting, acid reflux, May interact with insulin,
increase motility of diazepam, atropine and
stomach and intestine digoxin.
Mannitol 0.5-3 g/kg 0.5-3 g/kg Osmotic diuretic for the Anuric renal failure or
treatment of head urinary tract obstruction,
trauma, glaucoma, intracranial hemorrhage,
oliguric renal failure pulmonary edema, CHF
Bromfenac (eye 0.09% 0.09% Anterior uveitis and Eye hemorrhage, corneal
drop) iritis ulceration, glaucoma
Latanoprost (eye 0.005 % 0.005 % Primary glaucoma Excessive use causes
drop) miosis
Ketorolac 0.5 % 0.5 % Inflammation Eye hemorrhage, corneal
tromethamine (eye ulceration, glaucoma
drop)
Dorzolamide 2% 2% Glaucoma Excessive use causes local
eye discomfort
Timolol 0.5 % 0.5 % Glaucoma Avoided in animals with
CHF and asthma and
obstructive pulmonary
diseases.
Cyclosporine 3 to 7 mg/kg 4 to 6 mg/kg Suppress the immune Avoided in animals with
system in diseases such kidney impairment, ulcers
as immune mediated
hemolytic anemia,
atopic dermatitis, and
KCS,prevent rejection
after kidney or bone-
marrow transplants,
allergic skin diseases
(atopic dermatitis)
Theophylline 6 to 10 mg/kg 4 mg/kg Dilation of the airways, Caution in animals with
adjunct treatment in severe heart disease,
heart failure, asthma, abnormal heart rhythms,
bronchitis and chronic kidney or liver
lung diseases impairment, high blood
pressure
Budesonide 0.5 mg 0.5 mg control and prevent Should not be used to
(Nebuliser symptoms caused by relieve sudden asthma
Suspension) asthma, reduced the attacks as it does not work
irritation and swelling of immediately
the airways.
Dexamethasone 0.2 to 6 mg/kg 0.2 to 6 mg/kg Part of a treatment plan Fungal infections,
for various conditions, pregnancy
shock, suppress the
immune system in
 autoimmune diseases
Prednisolone 0.2 to 6 mg/kg 0.2 to 6 mg/kg Allergies, Fungal infections,
inflammations, pregnancy
autoimmune diseases,
endotoxic shock.
Epinephrine 0.01 to 0.02 0.01 to 0.02 Severe asthmatic Pregnancy, ventricular
mg/kg- allergic mg/kg- allergic attacks, stimulate the premature beats
reactions; variety reactions; variety heart in CPR, increase
of epinephrine of epinephrine blood pressure during
doses have been doses have been anesthesia,
used in CPR used in CPR anaphylactic reactions
Phenobarbital 2 to 4 mg/kg 7.5 to 15 mg per Seizure, sedation Caution in animals with
cat anemia, heart, liver or lung
disease
Propofol 3 to 8 mg/kg - Anesthesia, seizures If given rapidly cause
apnea, slow the heart rate
and lower blood pressure,
Cats
Xylazine 1-2 mg/kg 0.44 to 1 mg/kg Sedation, analgesia, Heart disease, low blood
induce vomiting (cats) pressure, shock, breathing
problems, severe liver or
kidney disease, debilitated
patient, last trimester of
pregnancy
Ketamine 5 to 10 mg/kg 2-4 mg/kg (I/V); Anesthesia, restrain cats Eye injuries, head injuries
22 to 33 mg/kg
(I/M)
Thiopental 10 to 25 mg/kg 9 to 11 mg/kg Anesthesia Shock, head trauma, liver
disease, sight hounds dogs