What is the most prevalent manifestation of venous
October 30, 2018 thrombosis in APS? a. superficial thrombophlebitis 1. The age group with the highest burden of b. digital gangrene noncommunicable degenerative dse and related c. livedo reticularis disability belongs to the oldest old, variously defined as d. DVT a. >70-75 b. >75-80 8. In Behcet’s synd, the most dreaded complication is c. >80-85 a. pulmonary artery vasculitis d. >85-90 b. genital ulceration c. cerebral venous thrombosis 2. Who among our members of the population tend to d. bilateral panuveitis live longer? a. women 9. The most serious manifestation of SLE is b. men a. cognitive dysfunction c. both b. anemia c. pleuritis with pleural effusion 3. Behcet’s synd, a multisystem disorder primarily d. nephritis affects which of the ff areas? a. mouth 10. The basic ADLs consist of these selfcare tasks, b. genital areas except c. eyes a. dressing and undressing d. all b. eating c. managing money 4. Positive pathergy test is can be elicited in which of d. personal hygiene the ff conditions? a. SLE 11. The pneumococcal immunization is recommended b. RA to be given c. Behcet’s synd a. once at 50y d. Sjogren synd b. once at 65y c. once at 70y 5. What is the best screening test for SLE? d. annually a. ANA b. anti-Sm 12. WG is a vasculitis that mainly affects which organ c. Anti-dsDNA systems? d. antiphospholipid a. kidneys, respiratory tract, and liver b. kidneys and liver 6. Which microorganism is associated with higher c. kidneys and upper and lower respiratory relapse rates in patient with Wegener’s tract granulomatosis? d. upper respiratory tract a. S. aureus b. S. pneumoniae c. mycoplasma d. K. pneumoniae 13. A diagnosed case of SLE pt comes to your clinic for 18. Which medication for pregnant pts with lupus has follow up. Which among the ff diagnostic test will you evidence of teratogenicity in humans, but its benefits not include in the request? might outweigh risks in certain situations? a. hgb a. rituximab b. serum crea b. cyclophosphamide c. UA c. tacrolimus d. plt ct d. glucocorticoids e. ANA 19. A 16yo F came to the ER due to palpable pruritic rash 14. Which fetal manifestation is most prevalent in pts on both lower exs for 5d associated with joint pains with APS? affecting elbows, wrists, knees, and ankles; with colicky a. early fetal loss (<10w) abdominal pain. There were no melena nor b. late fetal loss (>10w) hematochezia. CBC and plt were normal. UA was c. premature birth among live births normal. How will you manage the case? a. oral prednisone at 1mkd 15. The ff statements on general principles of tx for b. start steroid pulse therapy vasculitis synd are true except c. observe and monitor disease course a. glucocorticoids should be started d. prednisone at 1mkd ff’d by immediately where irreversible organ damage cyclophosphamide is established b. aggressive therapy should be avoided for 20. The ff are true re Henoch-Schonlein purpura, vasculitic manifestations that usually do not except respond to therapy a. presents commonly with mucosal and eye c. glucocorticoids should be initiated in those lesions systemic vasculitides that for which there is no b. pts may experience recurrence of sxs established standard of therapy c. usually a self-limiting condition d. none d. steroids may be given for those with severe abdominal pain and progressive renal dse 16. Which dse condition will present with necrotizing vasculitis of the small arteries and veins with 21. Profound changes in body composition may be the granuloma formation? most evident and inescapable effect of aging. a. WG Interestingly, this is the only body component which b. IgA vasculitis continues to increase across life span c. polyarteritis nodosa a. waist circumference d. Churg-Strauss b. weight c. fat mass 17. In vasculitis synd, the prominent pathologic process d. lean body mass includes which of the ff? a. thrombosis b. damage to blood vessels and inflammation c. damage to blood vessels d. inflammation e. all 22. A 35/M had hx of prolonged fever of 3w duration, 27. An asthmatic 45/F developed joint pains, malaise, joint pains and anorexia. He suddenly erythematous painful nodules on both legs, and SOB. complains of testicular pains. CBC showed anemia and CBC showed anemia and eosinophilia. CXR showed leukocytosis. Testicular bx was done and showed pulmonary infiltrates. Which is most likely the dx? necrotizing vasculitis. Which vasculitides is closely a. microscopic polyangiitis associated to this case? b. Takayasu a. GCA c. WG b. Takayasu d. Churg-Strauss c. polyarteritis nodosa d. microscopic polyangiitis 28. Which of the ff dse condition affects small vessels and manifests with palpable purpura? 23. The most common clinical mx of SLE involves the a. polyarteritis nodosa __ system b. behcets a. renal c. churg-strauss b. neurologic d. Henoch-schonlein c. cutaneous d. hematologic 29. Which of the ff dses is GCA closely associated with? e. musculoskeletal a. polymyalgia rheumatica b. sjogrens 24. A 70/F diabetic pt presenting with R diabetic foot c. RA was started with IV antibiotics to control sepsis and d. SLE insulin to control blood sugar. However, she eventually underwent amputation. The interventions done 30. The presence of this clinical finding is necessary for decreased the period of morbidity but will not the dx of behcets synd? necessarily equate to increasing longevity. This is a a. bilateral panuveitis classic example of b. vasculitis a. longevity dividend c. recurrent aphthous ulcers b. compression of morbidity d. erythema nodosum c. both d. neither 31. The mainstay tx for any inflammatory life/organ threatening mx of SLE 25. Which of the ff clinical mx suggests dx of vasculitis? a. immunosuppression a. varicose veins b. NSAIDs b. proteinuria c. systemic glucocorticoids c. palpable purpura d. antimalarials d. prolonged fever e. all 32. A progeroid condition, which occurs as a de novo, noninherited mutation in lamin A gene with aging sxs 26. The kidneys are the most common organ affected in early childhood and death by 13y in average in which of the ff? a. laron synd a. sarcoidosis b. cockayne synd b. amyloidosis c. Hutchinson-gilford progeria synd c. sjogrens d. werner’s synd d. behcets 33. Based on the diagnostic criteria for the dx of SLE, 38. Who among these are more prone to prolonged which of the ff is correct to make the probable dx? disability? a. there should be greater than or equal to 4 of a. men these criteria b. women b. there should be greater than or equal to 2 of c. both these criteria c. there should be greater than or equal to 5 of 39. Brain atrophy occurs with aging after 60y. What these criteria present at anytime in the pt’s hx part of the brain shows the highest ave shrinkage? d. there should be greater than or equal to 3 of a. inferior temporal lobe these criteria b. orbitofrontal cortex e. none c. fusiform gyrus d. hippocampus 34. Which of the ff statements is/are true of Behcet’s synd 40. The 3 Ds of aging except a. it usually affects the young with the female a. drug reaction more affected than male b. dementia b. life expectancy is poor c. depression c. blindness is the only serious complication d. delirium d. all 41. p-ANCA vasculitis 35. The rates of cognitive impairments, such as A Polyarteritis nodosa memory problems, increasing with age b. Takayasu a. men are worse c. Churg-strauss b. men are better d. Henoch-Schonlein c. no difference between genders d. none 42. Necrotizing vasculitis affecting small arteries and veins with involvement of the lung and upper airways 36. The ff statements are true of APS, except a. WG a. there is recurrent arterial or venous b. Henoch-Schonlein thrombosis and/or pregnancy morbidity c. Takayasu b. it is an autoantibody mediated acquired d. churg-strauss thrombophilia 43. Which of the ff vasculitis synds affects large vessels c. the trigger is not known like the aorta? d. it may occur alone or in association with any a. Takayasu other autoimmune dse b. Henoch-schonlein e. none c. churg-strauss d. WG 37. Nephritis is the most serious complication of which of the ff? 44. Which is not included in the dx of behcets synd? a. Sjogren a. recurrent oral ulcers b. SLE b. recurrent genital ulcers c. scleroderma c. pathergy test d. behcets d. asthma e. RA 45. A 23/F consulted as outpt due to fever, night sweats, anorexia and wt loss of 10kgs in just 4w. she dev’d abdominal pains for 5d now and ff’d by nausea and vomiting which prompted the consult. BP on R arm was 160/100. BP on L arm is palpatory 80. Pulses on ___ are faint. What’s your dx? a. GCA b. WG c. Takayasu d. Polyarteritis nodosa
46. The most common venous thrombosis in pts with
APS? a. superficial thrombophlebitis b. PE c. livedo reticularis d. DVT
47. Which of the ff aging changes does not correctly
match to the corresponding organ system? a. endocrine-hypergonadism b. vascular-segmental or global ischemic changes in many tissues c. immune-increased infections and autoimmunity d. hepatic detoxification-increased exposure to dse-inducing endobiotics
48. What is the most common mx of diffuse CNS
lupus? a. psychosis b. cognitive dysfunction c. headache d. seizures e. mood disorder
49. An exposure to UV light causes flares of SLE in 70%
of pts a. true b. false
50. The prevalence of disability in selfcare and home
mgt increases steeply with aging a. it tends to be higher in women than in men b. it tends to be lower in women than in men c. no difference between gender d. none