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1. A drug which prevents uric acid synthesis 12.

Which one is the heaviest particulate


by inhibiting the enzyme xanthine
oxidase is
component of the cell?
(A) Aspirin (B) Allopurinol (A) Nucleus (B) Mitochondria
(C) Colchicine (D) Probenecid (C) Cytoplasm (D) Golgi apparatus
2. Which of the following is required for 13. Which one is the largest particulate of the
crystallization and storage of the
cytoplasm?
hormone insulin?
(A) Mn++ (B) Mg++ (A) Lysosomes
(C) Ca++ (D) Zn++ (B) Mitochondria
3. Oxidation of which substance in the body (C) Golgi apparatus
yields the most calories
(A) Glucose (B) Glycogen
(D) Entoplasmic reticulum
(C) Protein (D) Lipids 14. The degradative Processess are categorized
4. Milk is deficient in which vitamins? under the heading of
(A) Vitamin C (B) Vitamin A (A) Anabolism (B) Catabolism
(C) Vitamin B2 (D) Vitamin K
5. Milk is deficient of which mineral?
(C) Metabolism (D) None of the above
(A) Phosphorus (B) Sodium 15. The exchange of material takes place
(C) Iron (D) Potassium (A) Only by diffusion
6. Synthesis of prostaglandinsis is inhibited (B) Only by active transport
by
(A) Aspirin (B) Arsenic
(C) Only by pinocytosis
(C) Fluoride (D) Cyanide (D) All of these
7. HDL is synthesized and secreted from 16. The average pH of Urine is
(A) Pancreas (B) Liver (A) 7.0 (B) 6.0
(C) Kidney (D) Muscle
8. Which are the cholesterol esters that enter
(C) 8.0 (D) 0.0
cells through the receptor-mediated 17. The pH of blood is 7.4 when the ratio
endocytosis of lipoproteins hydrolyzed? between H2CO3 and NaHCO3 is
(A) Endoplasmin reticulum (A) 1 : 10 (B) 1 : 20
(B) Lysosomes
(C) Plasma membrane receptor
(C) 1 : 25 (C) 1 : 30
(D) Mitochondria 18. The phenomenon of osmosis is opposite
9. Which of the following phospholipids is to that of
localized to a greater extent in the outer (A) Diffusion (B) Effusion
leaflet of the membrane lipid bilayer?
(A) Choline phosphoglycerides
(C) Affusion (D) Coagulation
(B) Ethanolamine phosphoglycerides 19. The surface tension in intestinal lumen
(C) Inositol phosphoglycerides between fat droplets and aqueous
(D) Serine phosphoglycerides medium is decreased by
10. All the following processes occur rapidly
(A) Bile Salts (B) Bile acids
in the membrane lipid bilayer except
(A) Flexing of fatty acyl chains (C) Conc. H2SO4 (D) Acetic acid
(B) Lateral diffusion of phospholipids 20. Which of the following is located in the
(C) Transbilayer diffusion of phopholipids mitochondria?
(D) Rotation of phospholipids around their long
axes
(A) Cytochrome oxidase
11. Which of the following statement is (B) Succinate dehydrogenase
correct about membrane cholesterol? (C) Dihydrolipoyl dehydrogenase
(A) The hydroxyl group is located near the centre (C) All of these
of the lipid layer
21. The most active site of protein synthesis
(B) Most of the cholesterol is in the form of a
cholesterol ester is the
(C) The steroid nucleus form forms a rigid, planar (A) Nucleus (B) Ribosome
structure (C) Mitochondrion (D) Cell sap
29. Carrier protein can 22. The fatty acids can be transported into
(A) Transport only one substance and out of mitochondria through
(B) Transport more than one substance (A) Active transport
(C) Exchange one substance to another (B) Facilitated transfer
(D) Perform all of these functions (C) Non-facilitated transfer
30. A lipid bilayer is permeable to (D) None of these
(A) Urea (B) Fructose 23. Mitochondrial DNA is
(C) Glucose (D) Potassium (A) Circular double stranded
31. The Golgi complex (B) Circular single stranded
(A) Synthesizes proteins (C) Linear double helix
(B) Produces ATP (D) None of these
(C) Provides a pathway for transporting chemicals 24. The absorption of intact protein from the
(D) Forms glycoproteins gut in the foetal and newborn animals
32. The following points about microfilaments takes place by
are true except (A) Pinocytosis (B) Passive diffusion
(A) They form cytoskeleton with microtubules (C) Simple diffusion (D) Active transport
(B) They provide support and shape 25. The cellular organelles called “suicide
(C) They form intracellular conducting channels bags” are
(D) They are involved in muscle cell contraction (A) Lysosomes (B) Ribosomes
33. The following substances are cell (C) Nucleolus (D) Golgi’s bodies
inclusions except 26. From the biological viewpoint, solutions
(A) Melanin (B) Glycogen can be grouped into
(C) Lipids (D) Centrosome (A) Isotonic solution
34. Fatty acids can be transported into and (B) Hypotonic solutions
out of cell membrane by (C) Hypertonic solution
(A) Active transport (B) Facilitated transport (D) All of these
(C) Diffusion (D) Osmosis 27. Bulk transport across cell membrane is
35. Enzymes catalyzing electron transport accomplished by
are present mainly in the (A) Phagocytosis (B) Pinocytosis
(A) Ribosomes (C) Extrusion (D) All of these
(B) Endoplasmic reticulum 28. The ability of the cell membrane to act as
(C) Lysosomes a selective barrier depends upon
(D) Inner mitochondrial membrane (A) The lipid composition of the membrane
36. Mature erythrocytes do not contain (B) The pores which allows small molecules
(A) Glycolytic enzymes(B) HMP shunt enzymes (C) The special mediated transport systems
(C) Pyridine nucleotide(D) ATP (D) All of these
37. In mammalian cells rRNA is produced 1. The general formula of monosaccharides
mainly in the is
(A) Endoplasmic reticulum (A) CnH2nOn (B) C2nH2On
(B) Ribosome (C) CnH2O2n (D) CnH2nO2n
(C) Nucleolus 2. The general formula of polysaccharides
(D) Nucleus is
38. Genetic information of nuclear DNA is (A) (C6H10O5)n (B) (C6H12O5)n
transmitted to the site of protein synthesis (C) (C6H10O6)n (D) (C6H10O6)n
by 3. The aldose sugar is
(A) rRNA (B) mRNA (A) Glycerose (B) Ribulose
(C) tRNA (D) Polysomes (C) Erythrulose (D) Dihydoxyacetone
39. The power house of the cell is 4. A triose sugar is
(A) Nucleus (B) Cell membrane (A) Glycerose (B) Ribose
(C) Mitochondria (D) Lysosomes (C) Erythrose (D) Fructose
40. The digestive enzymes of cellular 5. A pentose sugar is
compounds are confined to (A) Dihydroxyacetone (B) Ribulose
(A) Lysosomes (B) Ribosomes (C) Erythrose (D) Glucose
(C) Peroxisomes (D) Polysomes 6. The pentose sugar present mainly in the
9. Two sugars which differ from one another heart muscle is
only in configuration around a single (A) Lyxose (B) Ribose
carbon atom are termed (C) Arabinose (D) Xylose
(A) Epimers (B) Anomers 7. Polysaccharides are
(C) Optical isomers (D) Stereoisomers (A) Polymers (B) Acids
10. Isomers differing as a result of variations (C) Proteins (D) Oils
in configuration of the —OH and —H on 8. The number of isomers of glucose is
carbon atoms 2, 3 and 4 of glucose are (A) 2 (B) 4
known as (C) 8 (D) 16
(A) Epimers (B) Anomers 15. In glucose the orientation of the —H and
(C) Optical isomers (D) Steroisomers —OH groups around the carbon atom 5
11. The most important epimer of glucose is adjacent to the terminal primary alcohol
(A) Galactose (B) Fructose carbon determines
(C) Arabinose (D) Xylose (A) D or L series
12. -D-glucose and -D-glucose are (B) Dextro or levorotatory
(A) Stereoisomers (B) Epimers (C) and anomers
(C) Anomers (D) Keto-aldo pairs (D) Epimers
13. -D-glucose + 1120 + 52.50 + 190 - 16. The carbohydrate of the blood group
D-glucose for glucose above represents substances is
(A) Optical isomerism (B) Mutarotation (A) Sucrose (B) Fucose
(C) Epimerisation (D) D and L isomerism (C) Arabinose (D) Maltose
14. Compounds having the same structural 17. Erythromycin contains
formula but differing in spatial (A) Dimethyl amino sugar
configuration are known as (B) Trimethyl amino sugar
(A) Stereoisomers (B) Anomers (C) Sterol and sugar
(C) Optical isomers (D) Epimers (D) Glycerol and sugar
25. The monosaccharide units are linked by 18. A sugar alcohol is
1 4 glycosidic linkage in (A) Mannitol (B) Trehalose
(A) Maltose (B) Sucrose (C) Xylulose (D) Arabinose
(C) Cellulose (D) Cellobiose 19. The major sugar of insect hemolymph is
26. Which of the following is a non-reducing (A) Glycogen (B) Pectin
sugar? (C) Trehalose (D) Sucrose
(A) Isomaltose (B) Maltose 20. The sugar found in DNA is
(C) Lactose (D) Trehalose (A) Xylose (B) Ribose
27. Which of the following is a reducing (C) Deoxyribose (D) Ribulose
sugar? 21. The sugar found in RNA is
(A) Sucrose (B) Trehalose (A) Ribose (B) Deoxyribose
(C) Isomaltose (D) Agar (C) Ribulose (D) Erythrose
28. A dissaccharide formed by 1,1-glycosidic 22. The sugar found in milk is
linkage between their monosaccharide (A) Galactose (B) Glucose
units is (C) Fructose (D) Lactose
(A) Lactose (B) Maltose 23. Invert sugar is
(C) Trehalose (D) Sucrose (A) Lactose (B) Sucrose
29. A dissaccharide formed by 1,1-glycosidic (C) Hydrolytic products of sucrose
linkage between their monosaccharide (D) Fructose
units is 24. Sucrose consists of
(A) Lactose (B) Maltose (A) Glucose + glucose
(C) Trehalose (D) Sucrose (B) Glucose + fructose
30. Mutarotation refers to change in 34. The constituent unit of inulin is
(A) pH (B) Optical rotation (A) Glucose (B) Fructose
(C) Conductance (D) Chemical properties (C) Mannose (D) Galactose
31. A polysacchharide which is often called 35. The polysaccharide found in the
animal starch is exoskeleton of invertebrates is
(A) Glycogen (B) Starch (A) Pectin (B) Chitin
(C) Inulin (D) Dextrin (C) Cellulose (D) Chondroitin sulphate
32. The homopolysaccharide used for 36. Which of the following is a heteroglycan?
intravenous infusion as plasma substitute (A) Dextrins (B) Agar
is (C) Inulin (D) Chitin
(A) Agar (B) Inulin 37. The glycosaminoglycan which does not
(C) Pectin (D) Starch contain uronic acid is
33. The polysaccharide used in assessing the (A) Dermatan sulphate
glomerular fittration rate (GFR) is (B) Chondroitin sulphate
(A) Glycogen (B) Agar (C) Keratan sulphate
(C) Inulin (D) Hyaluronic acid (D) Heparan sulphate
43. A polymer of glucose synthesized by the 38. The glycosaminoglycan which does not
action of leuconostoc mesenteroids in a contain uronic acid is
sucrose medium is (A) Hyaluronic acid
(A) Dextrans (B) Dextrin (B) Heparin
(C) Chondroitin sulphate
(C) Limit dextrin (D) Inulin (D) Dermatan sulphate
44. Glucose on reduction with sodium 39. Keratan sulphate is found in abundance
amalgam forms in
(A) Dulcitol (B) Sorbitol (A) Heart muscle (B) Liver
(C) Mannitol (D) Mannitol and sorbitol (C) Adrenal cortex (D) Cornea
45. Glucose on oxidation does not give 40. Repeating units of hyaluronic acid are
(A) Glycoside (B) Glucosaccharic acid (A) N-acetyl glucosamine and D-glucuronic acid
(C) Gluconic acid (D) Glucuronic acid (B) N-acetyl galactosamine and D-glucuronic
46. Oxidation of galactose with conc HNO3 acid
yields (C) N-acetyl glucosamine and galactose
(A) Mucic acid (B) Glucuronic acid (D) N-acetyl galactosamine and L- iduronic acid
(C) Saccharic acid (D) Gluconic acid 41. The approximate number of branches in
47. A positive Benedict’s test is not given by amylopectin is
(A) Sucrose (B) Lactose (A) 10 (B) 20
(C) Maltose (D) Glucose (C) 40 (D) 80
48. Starch is a 42. In amylopectin the intervals of glucose
(A) Polysaccharide (B) Monosaccharide units of each branch is
(C) Disaccharide (D) None of these (A) 10–20 (B) 24–30
49. A positive Seliwanoff’s test is obtained (C) 30–40 (D) 40–50
with 54. ADH test is based on the measurement of
(A) Glucose (B) Fructose (A) Specific gravity of urine
(C) Lactose (D) Maltose (B) Concentration of urea in urine
50. Osazones are not formed with the (C) Concentration of urea in blood
(A) Glucose (B) Fructose (D) Volume of urine in ml/minute
(C) Sucrose (D) Lactose 55. The specific gravity of urine normally
51. The most abundant carbohydrate found ranges from
in nature is (A) 0.900–0.999 (B) 1.003–1.030
(A) Starch (B) Glycogen (C) 1.000–1.001 (D) 1.101–1.120
(C) Cellulose (D) Chitin 56. Specific gravity of urine increases in
52. Impaired renal function is indicated when (A) Diabetes mellitus
the amount of PSP excreted in the first 15 (B) Chronic glomerulonephritis
minutes is (C) Compulsive polydypsia
(A) 20% (B) 35% (D) Hypercalcemia
(C) 40% (D) 45% 57. Fixation of specific gravity of urine to
53. An early feature of renal disease is 1.010 is found in
(A) Impairment of the capacity of the tubule to (A) Diabetes insipidus
perform osmotic work (B) Compulsive polydypsia
62. Fructose is present in hydrolysate of (C) Cystinosis
(A) Sucrose (B) Inulin (D) Chronic glomerulonephritis
(C) Both of the above (D) None of these 58. Addis test is the measure of
63. A carbohydrate found in DNA is (A) Impairment of the capacity of the tubule to
(A) Ribose (B) Deoxyribose perform osmotic work
(C) Ribulose (D) All of these (B) Secretory function of liver
64. Ribulose is a these (C) Excretory function of liver
(A) Ketotetrose (B) Aldotetrose (D) Activity of parenchymal cells of liver
(C) Ketopentose (D) Aldopentose 59. Number of stereoisomers of glucose is
65. A carbohydrate, commonly known as (A) 4 (B) 8
dextrose is (C) 16 (D) None of these
(A) Dextrin (B) D-Fructose 60. Maltose can be formed by hydrolysis of
(C) D-Glucose (D) Glycogen (A) Starch (B) Dextrin
66. A carbohydrate found only in milk is (C) Glycogen (D) All of these
(A) Glucose (B) Galactose 61. α –D–Glucuronic acid is present in
(C) Lactose (D) Maltose (A) Hyaluronic acid (B) Chondroitin sulphate
67. A carbohydrate, known commonly as (C) Heparin (D) All of these
invert sugar, is 72. The carbon atom which becomes
(A) Fructose (B) Sucrose asymmetric when the straight chain form
(C) Glucose (D) Lactose of monosaccharide changes into ring
68. A heteropolysacchraide among the form is known as
following is (A) Anomeric carbon atom
(A) Inulin (B) Cellulose (B) Epimeric carbon atom
(C) Heparin (D) Dextrin (C) Isomeric carbon atom
69. The predominant form of glucose in (D) None of these
solution is 73. The smallest monosaccharide having
(A) Acyclic form furanose ring structure is
(B) Hydrated acyclic form (A) Erythrose (B) Ribose
(C) Glucofuranose (C) Glucose (D) Fructose
(D) Glucopyranose 74. Which of the following is an epimeric pair?
70. An L-isomer of monosaccharide formed in (A) Glucose and fructose
human body is (B) Glucose and galactose
(A) L-fructose (B) L-Erythrose (C) Galactose and mannose
(C) L-Xylose (D) L-Xylulose (D) Lactose and maltose
71. Hyaluronic acid is found in 75. -Glycosidic bond is present in
(A) Joints (B) Brain (A) Lactose (B) Maltose
(C) Abdomen (D) Mouth (C) Sucrose (D) All of these
82. Lactate formed in muscles can be utilised 76. Branching occurs in glycogen
through approximately
(A) Rapoport-Luebeling cycle after every
(B) Glucose-alanine cycle (A) Five glucose units
(C) Cori’s cycle (B) Ten glucose units
(D) Citric acid cycle (C) Fifteen glucose units
83. Glucose-6-phosphatase is not present in (D) Twenty glucose units
(A) Liver and kidneys 77. N–Acetylglucosamnine is present in
(B) Kidneys and muscles (A) Hyaluronic acid (B) Chondroitin sulphate
(C) Kidneys and adipose tissue (C) Heparin (D) All of these
(D) Muscles and adipose tissue 78. Iodine gives a red colour with
84. Pyruvate carboxylase is regulated by (A) Starch (B) Dextrin
(A) Induction (B) Repression (C) Glycogen (D) Inulin
(C) Allosteric regulation(D) All of these 79. Amylose is a constituent of
85. Fructose-2, 6-biphosphate is formed by (A) Starch (B) Cellulose
the action of (C) Glycogen (D) None of these
(A) Phosphofructokinase-1 80. Synovial fluid contains
(B) Phosphofructokinase-2 (A) Heparin
(C) Fructose biphosphate isomerase (B) Hyaluronic acid
(D) Fructose-1, 6-biphosphatase (C) Chondroitin sulphate
86. The highest concentrations of fructose are (D) Keratin sulphate
found in 81. Gluconeogenesis is decreased by
(A) Aqueous humor (B) Vitreous humor (A) Glucagon (B) Epinephrine
(C) Synovial fluid (D) Seminal fluid (C) Glucocorticoids (D) Insulin
87. Glucose uptake by liver cells is 91. Debranching enzyme is absent in
(A) Energy-consuming (B) A saturable process (A) Cori’s disease
(C) Insulin-dependent (D) Insulin-independent (B) Andersen’s disease
88. Renal threshold for glucose is decreased (C) Von Gierke’s disease
in (D) Her’s disease
(A) Diabetes mellitus (B) Insulinoma 92. McArdle’s disease is due to the deficiency
(C) Renal glycosuria (D) Alimentary glycosuria of
89. Active uptake of glucose is inhibited by (A) Glucose-6-phosphatase
(A) Ouabain (B) Phlorrizin (B) Phosphofructokinase
(C) Digoxin (D) Alloxan (C) Liver phosphorylase
90. Glucose-6-phosphatase is absent or (D) muscle phosphorylase
deficient in 93. Tautomerisation is
(A) Von Gierke’s disease (A) Shift of hydrogen (B) Shift of carbon
(B) Pompe’s disease (C) Shift of both (D) None of these
(C) Cori’s disease 94. In essential pentosuria, urine contains
(D) McArdle’s disease (A) D-Ribose (B) D-Xylulose
100. An amphibolic pathway among the (C) L-Xylulose (D) D-Xylose
following is 95. Action of salivary amylase on starch leads
(A) HMP shunt (B) Glycolysis to the formation of
(C) Citirc acid cycle (D) Gluconeogenesis (A) Maltose (B) Maltotriose
101. Cori’s cycle transfers (C) Both of the above (D) Neither of these
(A) Glucose from muscles to liver 96. Congenital galactosaemia can lead to
(B) Lactate from muscles to liver (A) Mental retardation
(C) Lactate from liver to muscles (B) Premature cataract
(D) Pyruvate from liver to muscles (C) Death
102. Excessive intake of ethanol increases the (D) All of the above
ratio: 97. Uridine diphosphate glucose (UDPG) is
(A) NADH : NAD+ (B) NAD+ : NADH (A) Required for metabolism of galactose
(C) FADH2 : FAD (D) FAD : FADH2 (B) Required for synthesis of glucuronic acid
103. Ethanol decreases gluconeogenesis by (C) A substrate for glycogen synthetase
(A) Inhibiting glucose-6-phosphatase (D) All of the above
(B) Inhibiting PEP carboxykinase 98. Catalytic activity of salivary amylase
(C) Converting NAD+ into NADH and decreasing requires the presence of
the availability of pyruvate (A) Chloride ions (B) Bromide ions
(D) Converting NAD+ into NADH and decreasing (C) Iodide ions (D) All of these
the availability of lactate 99. The following is actively absorbed in the
104. Glycogenin is intestine:
(A) Uncoupler of oxidative phosphorylation (A) Fructose (B) Mannose
(B) Polymer of glycogen molecules (C) Galactose (D) None of these
(C) Protein primer for glycogen synthesis
(D) Intermediate in glycogen breakdown
105. During starvation, ketone bodies are used
as a fuel by
(A) Erythrocytes (B) Brain
(C) Liver (D) All of these
106. Animal fat is in general
(A) Poor in saturated and rich in polyunsaturated
fatty acids
(B) Rich in saturated and poor in
polyunsaturated
fatty acids
(C) Rich in saturated and polyunsaturated fatty
acids
(D) Poor in