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COURSE PLAN (2018 July-December)
Department : Biotechnology
Course Name & code : Biology for engineers; BIO1001 (3 Credits)
Semester & branch : I and II sem
Name of the faculty :
ASSESSMENT PLAN:
1. In Semester Assessments - 50 %
CO1: The basic elements and their bonding ability, macromolecules and their structures and their role
and general law of thermodynamics in biological systems.
CO2: Mendel’s rules for inheritance, chromosomal theory of inheritance, relationship of Mendelian
inheritance to meiosis and pedigree analysis of genetic disorder diseases.
CO3: DNA as hereditary material, its replication, protein synthesis and their variation in Central Dogma
for eukaryotes, prokaryotes & Viruses
CO4: Evolution as a tool for improvising existing life forms and few examples of evolutionary
modifications.
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CO5: Few case studies which gives insight in to overall picture of life from micro-level to macro-level
and few application in Biotechnology.
Course Plan
Lecture CO
Topics
s
1 Introducing the topic
Elements of Life, Explanation about the important elements in any organism. 1
2
Electronegativity of the element, Importance of carbon.
ent types of bonds, Some examples of different types of bonding in the biological
3
systems
4 Water & phospholipid their importance in existence of life
5 Carbohydrates, ATP
6 Proteins and their structures.
7 Enzymes and how enzymes functions with one typical example, Effect of pH
8 Bioenergetics, glycolysis pathway
9 Mendelian concept of inheritance and Logic of Mendel 2
10 Monohybrid cross and segregation
Terminologies, Back cross and test cross, Dihybrid cross, Law of independent
11
assortment.
12 Chromosomes and cell division, chromosomal theory of inheritance
13 Morgan’s experiment, X-linked inheritance
14 Pedigree analysis
Discovery of DNA - Griffith transformation experiment, Hershey chase experiment, 3
15
Chargaff’s rule
16 Structure of DNA, Meselson and Stahl experiment. Kornberg experiment
17 DNA replication, Mechanism of replication -proof reading and editing.
18 RNA synthesis (Transcription), process of transcription.
19 Post transcriptional modification (RNA processing).
General characteristics of genetic code or triplet. Translation- initiation, elongation
20
and termination. problems
21 Transcription
22 Translation
23 Prokaryotic gene function: lac operon
4
24 Lamark and Darwin-Theories of evolution-I
25 Lamark and Darwin- Theories of evolution -II
26 Evidences of evolution-I
27 Evidences of evolution-II
28 Mechanism of evolution: Mutation Gene flow, genetic drift and nonrandom mating
29 Constraints on evolution and Relationships in nature
30 Vaccination 5
31 Concept of cloning
32 Ascent of sap-plant water relations
33 Lac operon
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34 Virus replication
35 Bioinspiration and Biomimetics
36 Summarizing the course
Reference Books:
Sadava D, Hillis D, Heller HC and Berenbaum MR, 2011. Life, the science of Biology, 9th edition. Sinauer
Associates, Inc USA. ISBN ISBN 978-1-4292-1962-4
Reece JB, Urry LA, Cain ML, Wasserman SA, Minorsky PV and Jackson RB, 20. Campbhell Biology, 9th
edition, Pearson Publications, USA. ISBN-13: 978-0-321-55823-7
Johnson AT, 2010. Biology for Engineers, CRC Press Inc., USA, ISBN 9781420077636
Hall, B. and Strickberger, M.W., 2008. Strickberger's evolution. Jones & Bartlett Learning.
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