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Cefuroxime axetil (ceftin) and cefuroxime sodium (zinacef) are antibiotics used to Treat bacterial infections. Antibiotics are a class of antibiotics called cephalosporins (second generation)
Cefuroxime axetil (ceftin) and cefuroxime sodium (zinacef) are antibiotics used to Treat bacterial infections. Antibiotics are a class of antibiotics called cephalosporins (second generation)
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Cefuroxime axetil (ceftin) and cefuroxime sodium (zinacef) are antibiotics used to Treat bacterial infections. Antibiotics are a class of antibiotics called cephalosporins (second generation)
Drepturi de autor:
Attribution Non-Commercial (BY-NC)
Formate disponibile
Descărcați ca DOC, PDF, TXT sau citiți online pe Scribd
DRUG CLASSIFI- MECHANISM IMPLICATION CONTRAINDI - ADVERSE INTER- NURSING
CATION OF ACTION CATION EFFECTS ACTION CONSIDERATION
ORAL (cefuroxime GENERIC Antibiotic Bactericidal: axetil) • Contraindicated • CNS: DRUG-DRUG ASSESSMENT NAME: Cephalosporin Inhibits with allergy to Headache, • Increased History: Hepatic and Cefuroxime (second synthesis of • Pharyngitis, tonsillitis cephalosporins or dizziness, nephrotoxicity renal impairment, generation) bacterial cell caused by penicillins lethargy, with lactation, pregnancy BRAND NAME: wall, causing Streptococcus paresthesias aminoglycosides Physical: Skin Cefuroxime axetil cell death pyogenes • Use cautiously • GI: nausea, • Increased status, LFT’s, renal (ceftin) • Otitis media caused with renal failure, vomiting, bleeding effects function tests, culture by Streptococcus lactation, diarrhea, with oral of affected area, Cefuroxime pneumoniae, pregnancy anorexia, anticoagulants sensitivity tests sodium (Zinacef) S.pyogenes, abdominal • Risk of Haemophilus pain, flatulence, disulfiram-like INTERVENTIONS DOSAGE: influenzae, Moraxella pseudomembra reaction with •Culture infection, Adults and nous colitis, alcohol and arrange for patients 12 yr catarrhalis and older • Acute bacterial hepatotoxicity sensitivity tests 250mg bid. For maxillary sinusitis • GU: DRUG-LAB before and during severe infections, caused by S. Nephrotoxicity TEST therapy if expected maybe increased pneumoniae, H. • Hematologic: response is not seen to 500mg bid. influenzae Bone marrow • Possibility of • Give oral drug with Treat up to 10 • Lower respiratory depression false results on food to decrease and days infections caused by S. (decreased tests of urine enhance absorption pneumoniae, WBC, glucose using • Give oral tablets to •Uncomplicated decreased Benedict’s children who can UTIs: 250mg bid. Haemophilus Treat for 7-10 parainfluenzae, platelets, solution, swallow tablets, days H.influenzae decreased Hct) Fehling’s crushing the drug • UTIs caused by •Hypersensitiv solution, Clinitest results in bitter, PARENTERAL E.coli, Klebsiella ity: Ranging tablets; urinary unpleasant taste. Use ADULTS pneumoniae from rash to 17-ketosteroids; solution to children 750mg-1.5g IM or •Uncomplicated fever to direct Coomb’s who cannot swallow IV every 8 hr, gonorrhea (urethral and anaphylaxis; test tablets depending on endocervical) serum sickness • Have vitamin K severity of abscess available in case of infection, for 5-10 • Skin and skin days structure infections, reaction hypothrombenemia including impetigo • Local: pain, occurs PEDIATRIC caused by S. aureus, abscess at • Discontinue if PATIENTS S. pyogenes injection site, hypersensitivity OLDER THAN 3 • treatment of early lime phlebitis, occurs MONTHS disease inflammation at IV site TEACHING POINTS 50-100 mg/kg/day PARENTERAL • Other: IM or IV in divided Superinfections Oral drugs doses every 6-8 hr (cefuroxime sodium) , disulfiram-like ROUTE: • Lower respiratory reaction with • Take full course of infections caused by alcohol therapy even if you IV, IM, ORAL S.pneumoniae, are feeling better S.aureus, E.coli, • This drug is specific K.pneumoniae, H. for this infection and influenzae, S. should not be used to pyogenes self-treat other problems • Dematologic • Swallow tablets infections caused by S. whole; do not crush aureus, S.pyogenes, them. Take the drug E.coli, K. pneumoniae, with food Enterobacter • Store solution in the • UTIs caused by refrigerator. Shake E.coli, K.pneumoniae well before each use • Uncomplicated and • You may experience disseminated this side-effects: gonorrhea caused N. stomach upset or gonorrheae diarrhea • Septicemia caused by • Report severe S. pneumoniae, diarrhea with S.aureaus, E.coli, blood,pus or mucus; K,pneumoniae, rash, difficulty H.influenzae breathing; unusual • Meningitis caused by tiredness, fatigue; S. pneumoniae, unusual bleeding or H.influenzae, S.aureus, bruising; unusual N. meningitis itching or irritation • Bone and joint infections due to S. PARENTERAL aureus DRUG • Perioperative • Avoid alcohol while prophylaxis taking this drug and • Treatment of Acute for 3 days after bacterial maxillary because severe sinusitis in patients reactions often occur 3mo-12yr • You may experience these side effects: Stomach upset or diarrhea • Report severe diarrhea, difficulty breathing, unusual tiredness or fatigue, pain at injection site.