Name: ___________________________________ Period: ____________ Date: ______________

2.6 Practice with Punnett Squares 

Activity #1: Do NOW K-L Chart
K= Know​: L= Learned:
2 things I learned from the ​Sun Sneeze Video​ are...

1.What is the ​genotype​ of a male who is 1.___________________________________________

homozygous recessive for blonde hair color?
____________________________________________
______________________________
2.___________________________________________
2. What is the ​genotype​ of a male who is
heterozygous for the widow’s peak​?
____________________________________________

_____________________________

 
Activity #2: Punnett Square Guided Practice 
Given that:
Body Color Y= yellow y= blue

Body Shape S= square s= round

1. SpongeBob SquarePants recently met SpongeSusie Roundpants at a dance. ​SpongeBob is

heterozygous for his square shape​, but ​SpongeSusie is round​.What are the offspring
possibilities?
​SpongeBob Genotype​: _________ SpongeSusie Genotype:​ _________

Punnett Square List the possible ​genotypes and phenotypes for their children​.

a. What are the chances of a ​child with a square

shape?​ ____ out of ____ or ____%

b. What are the chances of a ​child with a round

shape?​ ____ out of ____ or ____%

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 Name: ___________________________________ Period: ____________ Date: ______________

Given that:
Head height T= tall t = short

Body Color P = pink p = red

2. Patrick met Patti at the dance. Both of them are ​heterozygous for their pink body
color,​ which is dominant over a red body color.
a. Create a Punnett square to show the possibilities that would result if Patrick and
Patti had children.

Patrick Genotype​: _________ Patti Genotype:​ _________

Punnett Square List the possible ​genotypes and phenotypes for their
children​.

a. What are the chances of a ​child with a

pink body?​ ____ out of ____ or ____%

b. What are the chances of a ​child with a

red body?​ ____ out of ____ or ____%

 
 
 
 
 
 
 
 
 
 
 

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 Name: ___________________________________ Period: ____________ Date: ______________

Activity #3: Partner Practice!

3. Everyone in Squidward’s family has ​light blue skin,​ which is the​ dominant trait for
body color​ in his hometown of Squid Valley. His family brags that they are a “purebred” line
(​homozygous dominant​). He recently married a nice ​girl who has light green skin,
which is a recessive trait.

a. Create a Punnett square to show the possibilities that would result if

Squidward and his new bride had children. Use B to represent the dominant
gene and b to represent the recessive gene.

Squidward Genotype​: _________ Squidward’s Bride Genotype:​ _________

Punnett Square List the possible ​genotypes and phenotypes for their
children​.

a. What are the chances of a child with ​light

blue skin​? ____ out of ____ or ____%

b. What are the chances of a child with ​light

green skin?​ ____ out of ____ or ____%

c. Would Squidward’s children still be

considered ​purebreds (homozygous
dominant or homozygous recessive)​?
Explain!
____________________________________
____________________________________
____________________________________
____________________________________
____________________________________
____________________________________
___________________________________

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 Name: ___________________________________ Period: ____________ Date: ______________

4. ​Assume that one of Squidward’s sons, who is​ heterozygous for the light blue body color​, married a ​girl
that was also heterozygous​. Create a Punnett square to show the possibilities that would result if they had
children.
​Boy Genotype​: _________ Girl Genotype:​ _________

Punnett Square List the possible ​genotypes and phenotypes for their children​.

a. What are the chances of a child with ​light

blue skin​? ____ out of ____ or ____%

b. What are the chances of a child with ​light

green skin?​ ____ out of ____ or ____%

 
5. Mr. Krabbs and his wife recently had a Lil’ Krabby, but it has not been a happy occasion for them. Mrs.
Krabbs has been upset since she first saw her ​new baby who had small eyes​. She claims that the hospital
goofed and mixed up her baby with someone else’s baby. ​Mr. Krabbs is homozygous for his big eyes,
while ​his wife is heterozygous for her big eyes.​ Some members of her family have​ small eyes, which is
the recessive trait​.
a. Create a Punnett square using B for the dominant gene and b for the recessive one.

Mr. Krabbs Genotype:​ _________​Mrs. Krabbs Genotype:​ _________

Punnett Square

a. What are the chances of a child with ​big eyes​? ____ out of ____ or ____%

b. What are the chances of a child with ​small eyes?​ ____ out of ____ or ____%

c. They took home a baby with small eyes. Did the hospital make a mistake? Explain.
____________________________________________________________________
____________________________________________________________________

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 Name: ___________________________________ Period: ____________ Date: ______________

Activity #4: Practice makes perfect! 

Directions: U​ se the information given to you to
answer the problems that follow:

Genotype Circle one: Phenotype

LL Homozygous dominant Homozygous recessive Heterozygote

yy Homozygous dominant Homozygous recessive Heterozygote

Ss Homozygous dominant Homozygous recessive Heterozygote

RR Homozygous dominant Homozygous recessive Heterozygote

Rr Homozygous dominant Homozygous recessive Heterozygote

ll Homozygous dominant Homozygous recessive Heterozygote

ss Homozygous dominant Homozygous recessive Heterozygote

Yy Homozygous dominant Homozygous recessive Heterozygote

Genotype Phenotype

yellow body

roundpants

oval eyes

long nose

stubby nose

round eyes

squarepants

blue body

Genotype Phenotype

heterozygous round eyes

purebred squarepants

homozygous long nose

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 Name: ___________________________________ Period: ____________ Date: ______________

1. One of SpongeBob’s cousins,

SpongeBillyBob, recently met a cute
squarepants gal, SpongeGerdy​, at a
local dance and fell in love. Use your
knowledge of genetics to answer the
questions below.

a. If SpongeGerdy’s​ father is a
heterozygous squarepants ​and her ​mother is a roundpants​, what is ​Gerdy’s genotype​?
Complete the Punnett square to show the possible genotypes that would result to help you determine
Gerdy’s genotype.
​Dad Genotype​: _________ Mom Genotype:​ _________

Punnett Square

a. What is Gerdy’s genotype? ____________

b. How do you know?
___________________________________________
___________________________________________

2. Nowyou know Gerdy’s genotype.

SpongeBillyBob is heterozygous for his
squarepants shape​. What is his genotype?
Complete the Punnett square below to show the
possibilities that would result if ​SpongeBillyBob
& Gerdy​ had children.

​SpongeBillyBob Genotype​: _________ Gerdy Genotype:​ _________

Punnett Square

a. What is SpongeBillyBob’s genotype? _______________________

b. What are the chances of a child with ​squarepants​? ____ out of ____ or ____%
c. What are the chances of a child with ​roundpants?​ ____ out of ____ or ____%

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 Name: ___________________________________ Period: ____________ Date: ______________

 
3. SpongeBob’s aunt and uncle, SpongeWilma and SpongeWilbur, have the biggest round eyes
in the family. ​Wilma is believed to be heterozygous for her round eye shape,​ while
Wilbur’s family brags that they are a purebred (homozygous dominant).​ Complete the
Punnett square to show the possibilities that would result if Wilma and Wilbur had children.

​Wilma Genotype:​: _________ Wilbur Genotype:​ _________

Punnett Square

a. What are the chances of a child with ​round eyes​? ____ out of ___ or ___ %

b. What are the chances of a child with ​oval eyes?​ ____ out of ____ or ____%

4. SpongeBob’s mother is so proud of her

son and his new wife, SpongeSusie, as they
are expecting a little sponge. She ​is
hoping the new arrival will be blue (a
recessive trait​) like SpongeSusie and
many members of her family. If
SpongeBob is heterozygous for his
yellow body color​ and ​SpongeSusie is
blue​, what are the ​chances that the baby sponge will be blue?

SpongeBob Genotype​: _________ SpongeSusie Genotype:​ _________

Punnett Square

a. What are the chances baby will be ​blue sponge​? ____ out of ___ or ___ %
b. What are the chances baby will be ​yellow sponge?​ ____ out of ____ or ___%

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 Name: ___________________________________ Period: ____________ Date: ______________

5. SpongeBob’s aunt is famous around town

for her tiny itty, bitty ​stubby nose​! She
recently met a cute squarepants fellow who
also has a ​stubby nose, which is a
recessive trait.​ ​What genotype would
the husband need to have in order for
the children to have a regular long
nose?
Create a Punnett square to help you answer this question.

Aunt Genotype​: _________ Boyfriend Genotype:​ _________

Punnett Square

a. What are the chances baby will be ​long nose​? ____ out of ___ or __ %

b. What are the chances baby will be ​stubby nose?​ ____ out of ____ or ___%

c. What genotype would the husband need to have in order for the children to
have a long nose? ____________________________________________

 
 
 
 

 
 
 

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 Name: ___________________________________ Period: ____________ Date: ______________

Activity #5: Read It​! “​All About Punnett Squares”

What do you get when you cross an apple and an orange?  CATCH Annotate CFS
Though the above fruit may not result, it would be nice to scientifically  ❏ Highlight one keypoint from
predict what would result. Predicting the possible genotypes and  each paragraph.
phenotypes from a genetic cross is often aided by a ​Punnett square​.  ❏ Circle 1-2 unknown/vocab
  words from each paragraph
Punnett Squares   ❏ Ask 1 question OR make 1
A ​Punnett square​ is a chart that allows you to easily determine the expected  connection
percentage of different genotypes in the offspring of two parents. An example of a  ❏ Answer ​Thinking Questions
Punnett square for ​pea plants​ is shown above. In this example, both parents are 
heterozygous​ for flower ​color​(​Bb​). The ​gametes​ produced by the male parent are at  1. ​ What is a ​punnett square? 
the top of the chart, and the gametes produced by the female parent are along the side.  _______________________________
The different possible combinations of ​alleles ​in their 
offspring are determined by filling in the squares of the  _______________________________
Punnett square with the correct letters (​alleles​).   ______________________________
  What does ​heterozygou​s 
This Punnett square shows a cross between two  2. ​
heterozygotes, Bb. ​Heterozygous ​means that there is one  mean​?
dominant and one recessive allele of the gene. Two pea 
plants, both heterozygous for flower color, are crossed. In  _______________________________
this ​heterozygous cross​, the offspring will show the  _______________________________
dominant purple color in a 3:1 ratio, meaning about 75% of 
the offspring will be purple.  _______________________________
  _______________________________
Predicting Offspring Genotypes    n a ​heterozygous cross​, what 
3​
In the cross shown in the picture, you can see that one out of four offspring (25 percent)  percentage of the offspring would 
has the ​genotype​ ​BB,​ one out of four (25 percent) has the genotype ​bb​, and two out of 
four (50 percent) have the genotype ​Bb​. These percentages of genotypes are what you  be purple in color?
would expect in any cross between two heterozygous parents. Of course, when just 
four offspring are produced, the actual percentages of genotypes may vary by chance  _______________________________
from the expected percentages. However, if you considered hundreds of such crosses  _______________________________
and thousands of offspring, you would get very close to the expected results, just like 
tossing a coin.  _______________________________
  What ​genotype gives a 
4.​ ​
Predicting Offspring Phenotypes   white-flower phenotype​ ? 
You can predict the percentages of ​phenotypes​ in the offspring of this cross from their 
genotypes. ​B​ is dominant to ​b​, so offspring with either the ​BB​ or ​Bb​ genotype will have  _______________________________
the purple-flower ​phenotype​. Only offspring with the ​bb​ ​genotype ​will have the  _______________________________
white-flower phenotype. Therefore, in this cross, you would expect three out of four (75 
percent) of the offspring to have purple flowers and one out of four (25 percent) to have  ______________________________
white flowers.   What else can a ​Punnett 
5. ​
  Square​ be used for? 
Determining Missing Genotypes 
A Punnett square can also be used to determine a missing genotype based on the other  _______________________________
genotypes involved in a cross. Suppose you have a parent plant with purple flowers 
and a parent plant with white flowers. Because the ​b​ allele is recessive, you know that  _______________________________
the white-flowered parent must have the genotype ​bb​. The purple-flowered parent, on  _______________________________
the other hand, could have either the ​BB​ or the ​Bb​ genotype. The Punnett square in 
Figure​ ​below​ shows this cross. The question marks (?) in the chart could be either ​B​ or 
b​ ​alleles​.
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Name: ___________________________________ Period: ____________ Date: ______________

Activity #6: Extra Practice!

Complete the Punnett Squares for each question below:
1. A tall (TT) plant is crossed with a short (tt) plant.
What percentage of the offspring will be tall? ________ Show all of your work
using a punnett square.

2. A Tt plant is crossed with a Tt plant.

What percentage of the offspring will be short? ________Show all of your work using a punnett square.

3. A heterozygous round-seed plant (Rr) is crossed with a homozygous round-seed plant (RR).
What percentage of the offspring will be homozygous (RR)? ___________ Show all of your work using
a punnett square.

4. ​In pea plants, purple flowers (F) are dominant over white flowers (f).
If two white flowers are crossed, what percentage of the offspring will be white flowers? __________
Show all of your work using a punnett square.

5. A white flower is crossed with a plants that is heterozygous for the trait.
What percentage of the offspring will have purple flowers? ___________ Show all of your work using a
punnett square.

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