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DRUGS
Table of Contents
Amlodipine Diazepam
Aspirin Digoxin Lidocaine HCl
Atropine Sulfate Diphenhydramine
Dobutamine Mannitol
Bricanyl Dopamine Methergine
Bupivacaine Dynastat Methylergonovine Maleate
Buscopan Metronidazole
Butorphanol Tartrate Epinephrine Midazolam
Ephedrine Morphine Sulfate
Calcium Gluconate
Capoten Famotidine Nalbuphine HCl
Catapres Felodipine Nifedipine
Cefurosime Nitroglycerine
Celecoxib Gentamycin Norvasc
Clindamycin Nubaine
Clopidogrel Heparin
Co- amoxiclav Hydroxyzine Omeprazole
Hyperstat Osmofundin
Demerol Oxytocin
Diamicron Ketorolac
Sodium Bicarbonate
Phenergan Solu- Cortef Valium
Pilocarpine HCl Somazine Ventolin
Plasil Spiriva
Potassium Chloride Zantac
Toradol
Salbutamol Tramadol HCl
Simvastatin Tranexamic Acid
BSN IV Group 9B
Nursing
Drugs Action Indication Contraindication Adverse Reaction
Consideration
flushing
Do not
discontinue prior to
surgery; monitor
BP carefully during
surgery; have
other BP-
controlling drugs
readily available.
Reevaluate
therapy if clonidine
tolerance occurs;
giving concomitant
diuretic
increases the
antihypertensive
efficacy of
clonidine.
Monitor BP
carefully when
discontinuing
clonidine;
hypertension
usually returns
within 48 hr.
Drugs Mechanism Indication Contraindicati Adverse Nursing
of Action on Reaction Considerations
.
Cefuroxime Broad- It is effective for the Hypersensitivity GI: Determine history
spectrum treatment of to Diarrhea, of hypersensitivity
Classification: cephalosporin penicillinase- cephalosporins nausea, reactions to
Anti-infective; antibiotic producing Neisseria and related antibiotic- cephalosporins,
antibiotic resistant to gonorrhoea antibiotics; associated penicillins, and
beta- (PPNG). Effectively pregnancy colitis. history of allergies,
lactamase. It treats bone and joint (category B), Skin: particularly to
has been infections, lactation Rash, drugs, before
proposed for bronchitis, pruritus, therapy is initiated.
infections meningitis, urticaria. Inspect IM and IV
with gram- gonorrhea, otitis Urogenital injection sites
negative and media, : Increased frequently for
gram-positive pharyngitis/tonsillitis serum signs of phlebitis.
organisms, , sinusitis, lower creatinine Report onset of
gonorrhea, respiratory tract and BUN, loose stools or
and infections, skin and decreased diarrhea. Although
haemophilus. soft tissue creatinine pseudomembrano
infections, urinary clearance. us colitis.
tract infections, and Monitor I&O rates
is used for surgical and pattern:
prophylaxis, Especially
reducing or important in
eliminating infection. severely ill patients
receiving high
doses. Report any
significant
changes.
Drugs Action Indication Contraindication Adverse Reaction Nursing
Consideration
Celecoxib Inhibits Relief of signs Use in severe GI: Dyspepsia, Assess for
(Celebrex) prostaglandin and symptoms of hepatic diarrhea, renal and liver
synthesis, rheumatoid impairement, in abdominal pain. dysfunction.
Classification: primarily by arthritis and those who have
Nonsteroidal anti- inhibiting cyclo- osteoarthritis in shown an allergic Respiratory: Do not
inflammatory oxygenase-2; it adults. reaction to URI, sinusitis, consume
drug, COX-2 does not inhibit sulfonamides, or pharyngitis, rhinitis, alcoholic
inhibitor the Acute pain those who have bronchitis beverages while
cyclooxygenase- and primary experienced on this drug.
1 isoenzyme. dysmenorrhea in asthma, urticaria, Infections:
Does not affect adults. or allergic type Bacterial, fungal, or May take with
platelet reactions after viral infection. food to decrease
aggregation; Reduce the taking aspirin or GI upset.
renal effects number of other NSAIDS. Dermatologic:
similar to other adenomatous Rash, ecchymosis, Report weight
NSAIDS. colorectal polyps alopecia, dermatitis, gain, swelling of
in familial nail disorder. ankles, chest pain
adenolatous or SOB.
polyposis.
Nursing
Drugs Action Indication Contraindication Adverse Reaction
Consideration
Gliclazide Anti Diabetic Drug Stimulates Non- Type I diabetes; Hypoglycemia, Asses for
(Diamicron) insulin insulin diabetes GI hypoglycemic/hyperglycemic
Pharmacokinetics release from dependent complicated with disturbances, reactions.
Dosage: Absorption: pancreatic diabetes ketosis and dermatological
80 mg 1 tab Effectively absorbed beta cells. mellitus acidosis; reactions, Monitor CBC, glycosylated
OD in the GIT (NIDDM). pregnancy, biochemical hemoglobin during
Distribution: highly diabetics under- abnormalities, treatment.
bound to plasma going surgery, headache.
proteins (94%) hypersensitivity to Monitor liver and renal
Metabolism: liver sulfonylureas. function test periodically.
Excretion: Urine,
feces (10-20%) Assess for hypersensitivity of
Half life: 10.4 hrs the patient to medications.
Pharmacodynamics
Onset: unknown
Peak: 4-6 hrs
Duration: unknown
Felodipine Antihypertensive - Inhibit calcium Treatment of Hypotension Peripheral Assess fluid volume
Calcium Channel ion influx hypertension. with systolic BP Edema, status: input output ratio
Dosage: Blocker across cell <90mmHg Hypotension and record weight, skin
50 mg 1 tab membrane, Used to treat or Precautions: syncope turgor, adequacy of
OD Pharmacokinetics resulting in prevent Lactation, CHF, atrioventricul pulses, moist mucous
Absorption: well inhibition of cerebral hepatic ar block membranes, bilateral lung
absorbed excitation/ vasospasm impairment MI sound, peripheral pitting
Distribution: contraction. following a SA Arrhythmias edema, dehydrations
unknown hemorrhage, Angina symptoms of decreasing
Metabolism: liver Relaxes the which usually Tachycardia output thirst, hypotension,
Excretion: kidneys smooth occurs 4-14 Headache dry mouth.
Half life: 11-16 hrs. muscles of the days after a Dizziness.
vessel wall stroke, inhibits Monitor cardiac status:
Pharmacodynami and reducing blood flow to the BP, pulse, respiration,
cs incidence and area, and ECG periodically.
Onset: 2-3 hrs. severity of the worsens
Peak: 2 ½ -5 hrs. spasm. ischemia. Assess for anginal pain
Duration: less than duration, intensity,
24 hrs. Neurologic ameliorating, aggravating
function is factors.
improved and
further
deterioration
from ischemia
is prevented.
4.monitor vital
signs closely.
Report
significant
changes in BP
and signs of
CHF
o jaundice
(yellowing of
your skin or
eyes); or
o seizure
(convulsions)
Simvastatin Lipid-Regulating Inhibits HMG- To reduced LDL Hypersensitivity Abdominal Assess nutrition: fat,
(Zocor) Drugs – HMG-CoA COA (3- cholesterol, to any pain protein, carbohydrates,
Reductase hyroxy-3- apolipoprotein components of Constipation nutritional analysis should
Inhibitors -Statins methyglutaryl beta this preparation. Flatulence be completed by dietitian
Dosage: coenzyme) tryglycerides. To Acute Liver Nausea before treatment is
40mg 1 tab Pharmacokinetics reductase increase HDL Disease or Acid initiated.
OD hs Absorption: 85% enzyme, cholesterol in unexplained Vomiting
Distribution:Unkno which reduces the treatment of persistent Diarrhea Instruct the patient to take
wn cholesterol hyperlipidemias, elevations of Dyspepsia drug with the evening
Metabolism:Liver synthesis, this including serum Insomnia meal because taking this
extensively enzyme is hypercholesterol transaminases Anemia enhances absorption and
Excretion: 70% needed for aemias and Rashes increases cholesterol
feces, 20% kidney cholesterol combined Headache biosynthesis.
Half-life: 3 hrs production. hyperlipidaemia.
Teach patient about
Pharmacodynami proper dietary
cs management of
Onset: unknown cholesterol and
Peak: 1-hrs triglycerides.When
Duration: unknown appropriate; recommend
weight control, exercise
and smoking.
Citicoline CNS Stimulants/ Citicoline is a CVA in acute Hypertonia of Shock, Evaluate patient medical
(Somazine) Neurotonics derivative of and recovery the hypersensitivit history.
choline and phase. parasympathetic y,
Dosage: Pharmacokinetics cytidine involve Symptoms nervous system. hypotension, Assess patient’s
1 gm IV q 12 Absorption: almost in the and signs of insomnia, condition.
completely biosynthesis of cerebral excitement.
absorbed lecithin. It is insufficiency Monitor BP, pulse and
Distribution: claimed to (i.e., heart rate.
disperse widely increase dizziness,
throughout the blood flow headache, Assess allergic reaction
body: cross blood and oxygen poor like gastro intestinal
brain barrier consumption concentration, disturbances.
Metabolism: in the brain. memory loss,
unknown disorientation). Must not be administered
Excretion: unknown to patient with hypertonia
Half life: unknown of the parasympathetic
nervous system.
Pharmacodynami
cs
Onset: unknown
Peak: Unknown
Duration: unknown
DRUG NAME
MECHANISM INDICATION CONTRAINDICATI ADVERSE EFFECTS NURSING
OF ACTION ON CONSIDERATION
BRAND NAME: Long-acting Long-term, History of GI: Dry mouth, dyspepsia, · Docume
Spiriva antimuscarinic once daily, hypersensitivity to abdominal pain, constipation,
nt indications
GENERIC (anticholinergic maintenance atropine or its vomiting, gastroesophageal
NAME:Tiotropiu ). In the treatment of derivatives, including reflux, GI disorder, stomatitis for therapy,
m bromide airways it bronchospas ipratropium. Use for (including characteristic
CLASSIFICATI inhibits m associated initial treatment of ulcerative).CNS:Depression, of S&S, other
ON: muscarinic M3 with COPD, acute episodes of dysphonia,
receptors at the including bronchospasm paresthesia.Respiratory:URTI, agents trialed,
Anticholinergic
smooth muscle,chronic (rescue therapy). sinusitis, pharyngitis, rhinitis, and outcome.
leading to bronchitis and Use with other epistaxis, coughing, · Note
Dosage: bronchodilation emphysema. anticholinergics laryngitis. CV:Angina pectoris CXR, PFTs,
18mcg/cap OD . Since the drug (e.g., ipratropium). (including aggravated angina
is inhaled, the pectoris), atrial fibrillation, other drugs
majority is supraventricular tachycardia, prescribed
deposited in palpitation.Musculoskeletal:Art and overall
the GI tract hritis, skeletal pain, myalgia.
and, to a lesser GU: UTI, urinary physical
extent, the retention.Dermatologic:Rash
condition/
lungs (site of pruritus, urticaria. Body as a
action). The whole:Accident edema, clinical
portion infection, moniliasis, flulike presentation
metabolized is symptoms, allergic reaction, of client.
through the angioedema.Miscellaneous:her
CYP2D6 and pes zoster, leg pain, cataract, · Asses
CYP3A4 epistaxis. for any
enzyme evidence of
systems. QT
However, most
is excreted prolongation
unchanged on EKG, renal
through the dysfunction,
urine. ,
or inability to
terminal: 5-6
days. Plasma self
protein administer
binding: 72%. drug. Note
BPH, narrow
angle
glaucoma, or
bladder neck
obstraction,
as drug use
may
aggravate
these
conditions
3. Caution patient to
avoid concurrent
use of alcohol,
aspirin, NSAIDs,
acetaminophen, or
other OTC
medications without
consulting health
care professional.
4.Advise patient to
consult if rash,
itching, visual
disturbances,
tinnitus, weight
gain, edema, black
stools, persistent
headche, or
influenza-like
syndromes
(chills,fever,muscles
aches, pain) occur.
Drugs Action Indication Contraindication Adverse Reaction Nursing
Consideration