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Service Manual

Cat. 04005374
©2002 Bayer Corporation
All rights reserved
Flow Chart
CALIBRATE?

yes

ANALYZE SAMPLE?

yes no
LIFT SAMPLER TO
ANALYZE
Whole Blood, Serum, or Plasma Analysis no

DAILY CLEANER?

End of Day Cleaning yes no

ANALYZE QC?

Analyze Level 1, Level 2, Level 3 Controls yes no

CALIBRATE?

Calibration yes no

SECOND MENU?

yes no

ANALYZE URINE?

Urine Analysis yes no

STANDBY?

Fluid Conservation, Maintenance yes no

REPLACE
COMPONENTS?
Replace: Valve Module, Replace Others yes no

DIAGNOSTICS?

Test Fluidics, Test Components, Sensor Status, Prime Fluids yes no

STORED
INFORMATION?
View: Patient Results, QC Results, Calibration Data,
Reagent Module Status; yes no
Print: Setup
SETUP MENU?
Set: User Options, Configuration,
Calibration Options, Reference Limits; yes no
Delete: Patient/QC Data;
Adjust Display
Table of Symbols

▲ Important information

★ Conditions which may cause data loss or analyzer malfunction

Biohazard warning

Electrical hazard

i
Service Manual Contents

Software Flow Chart . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .inside front cover


Table of Symbols . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .i

Product Description

System Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .1
Sensor Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Sampler . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Valve Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .2
Printer Assembly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3
CPU Assembly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3
Pre-Amp PC Board . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3
Pump Assembly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .3
Contact Housing . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4
Display Assemblies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .4
Valve Module Cable . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
Rear Housing Assembly . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .5
Replacement List . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .6

Troubleshooting

Troubleshooting Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7
Troubleshooting Guide . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .7
AC Power Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .8
DC Power Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .9
Display Assembly Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .10
Flash Device Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .11
Printer Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .12
Pump Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13
Valve Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .13
Sensor Signal Input Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .14
Serial Communication Verification . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .15
Repair

Repair Overview . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16


Required Tools . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .16
Rear Housing Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
Rear Housing Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .17
Printer Assembly Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18
Printer Assembly Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .18
Display Assembly Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19
Display Assembly Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .19
CPU Assembly Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
CPU Assembly Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .20
Flash Device Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
Flash Device Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .21
Printer EPROM Removal and Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .22
Access Door Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23
Access Door Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .23
Pre-Amp PC Board/Contact Housing Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .24
Pre-Amp PC Board/Contact Housing Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .25
Valve Cable Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26
Valve Cable Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .26
Pump Assembly Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
Pump Assembly Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .27
Sampler Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28
Sampler Installation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .28
Software Upgrade Kit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .29
Appendixes: CPU Board Schematics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .A-J
Contacting Bayer Diagnostics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .K-N
P R O D U C T D E S C R I P T I O N N

System Overview

T he repairs and procedures in this manual are intended for authorized field service
engineers. Instructions describe the repair or replacement of all modular internal
components. It is recommended that the field service engineer also refer to the Operator’s
Manual for detailed instructions on operating and troubleshooting the analyzer to determine
if repair or replacement is necessary for an internal component. The Replacement List
indicates assemblies and components available to the field service engineer. Refer to the
Repair section of this manual for the CPU schematics.

All components should be considered biohazardous (contaminated with HIV or


other pathogens).
Any replaceable component which comes in contact with biological samples,
including the sampler, sensors, sensor module, pump tubing, valve module and
reagent module may contain contaminated material. Treat all components, during
use and disposal, as you would any biohazardous material.

1
P R O D U C T D E S C R I P T I O N N

Sensor Module
Contains sampler position sensors, bubble detector,
door sensor, sampler, and compression plate. The
Sensors Na+, K+, Cl-, spacer, and reference sensors
are housed in the sensor module.

Sampler
Attached to sensor module. Contains sample probe
with probe wiper. The sampler is removable from the
sensor module as a replacement part.

Valve Module
Controls reagent (from reagent module) or air
selection. The valve module contains a ceramic valve,
motor, position detector. There are no serviceable
parts inside the valve module.

2
P R O D U C T D E S C R I P T I O N

Printer Assembly
Contains the printer mechanism, printer software, and
printer electronics. Prints analysis, calibration and
diagnostic data.

CPU Assembly
Contains transformer, software, inputs (sensors),
motor control circuitry, and 2 serial ports.

Pre-amp PC Board
Connects contact housing to the CPU assembly and
amplifies sensor signals.

Pump Assembly
Contains peristaltic pump with wire connector.

3
P R O D U C T D E S C R I P T I O N N

Contact Housing
Contains all contacts from the sensors, as well as the
contact housing cable for connection to the CPU
assembly.

Display Assemblies
(Analyzer operator interface.) Contains operator
keypad and LCD display.

Graphic display
(required for certain languages)

Numeric display

4
P R O D U C T D E S C R I P T I O N

Valve Module Cable


Connects valve module to the CPU board.

Rear Housing Assembly


Rear housing contains the printer paper bay and
cover, serial number label, and the openings for the
fuse holder, AC power cord socket, battery connec-
tion, RS-232 serial interface connection, barcode
reader connection, and power voltage setting.

5
P R O D U C T D E S C R I P T I O N N

Replacement List
The items on this list are available for purchase from
Bayer Corporation.

Description Catalog Number


Access Door 05575077
Barcode Reader 07000853
Cable, Valve Module 04526455
Cl- Sensor 00661439
Compression Plate Assembly 00362008
Contact Housing 06813338
CPU Assembly 00667836
Display Assembly, Graphic 08818280
Display Assembly, Numeric 02034598
Downloadable Software Update 08041545
Downloadable Software Update,Japanese 01731201

Flash Prom Replacement Kit 04129944


Flash Prom Replacement Kit, Japanese 09642364
K+ Sensor 04955798
Na+ Sensor 04473866
Operator’s Manual 06921467
Pre-Amp PC Board 07876805
Printer Assembly 01739466
Probe Wiper Replacement Kit 05905239
Pump Assembly 02063997
Pump Tubing 07372033
Reagent Module Na+/K+/Cl- 02970609
Reference Sensor 02283180
Sampler 02377673
Sensor Module 05453710
Serial Cable, 25 pin 09371905
Serial Cable, 9 pin 02348746
Service Manual 04005374
Spacer Sensor 02451792
Valve Module 03372381

6
T R O U B L E S H O O T I N G

Troubleshooting Overview

This section describes troubleshooting the


mechanical and electrical functions of the
Rapidchem analyzer. Bayer recommends that
dealers maintain an inventory of operational test
assemblies for troubleshooting purposes. These test
assemblies can substitute the questionable
assemblies to confirm failures. Only those items
listed on the Replacement List are available for
purchase. For information on troubleshooting the
fluidic system and sensors, refer to the Rapidchem
Operator’s manual.

▲ Run quality control material after any


troubleshooting procedure.

▲ When removing or handling PC boards, it is


necessary to be properly grounded to prevent
static damage.

Troubleshooting Guide
Determine the problem and corrective action
needed.

Action Steps
Problem/Description Problem Source Corrective Action Steps

Blank display/No response Power malfunction AC power verification


Defective display DC power verification
Display assembly verification
Flash Device verification
Printer does not print Printer malfunction Printer verification
No pump movement Pump motor malfunction Pump verification
No valve movement Valve motor malfunction Valve verification
Sensor voltages out of Sensors or signal input Check sensor module installation
specification malfunction and performance
Sensor signal input verification
Serial transmission failure Serial cable Serial communication verification
Transmission Protocol

7
T R O U B L E S H O O T I N G G

AC Power Verification
When the power is first turned on, the Rapidchem
analyzer will “beep,” and the display will light up. If
this fails to happen, follow the verification procedure
in this section. Review this entire section before
replacing any components. First confirm that the
power cord is inserted securely inside the AC power
cord socket.

Warning: Careless handling of AC


power can be hazardous or fatal.
Only qualified personnel should
work with AC power.

Fuse Holder AC Power Cord Socket

220
220
110

11

or

Factory-set Power Voltage Setting

1 Remove the power cord from the AC power cord


socket.

2 Verify that the voltage selector switch voltage


setting (110V or 220V) matches the power outlet
voltage. If it does not, correct the setting.

★3 Verify that the fuses have the correct rating. Push


down on the fuse holder release tab and pull the F0.8 or F0.4
fuse holder straight out. Inspect both fuses.
• For 110V analyzers, the fuses must be rated
0.8A, 250 volts
• For 220V analyzers, the fuses must be rated
0.4A, 250 volts
8
T R O U B L E S H O O T I N G

Remove the fuses from the fuse holder. Using a


standard ohmmeter, measure continuity between the
ends of each fuse. Replace defective fuses.

If the voltage setting and the fuses are correct, but


“no power” or “blank display” continues, proceed as
follows:

4 Remove the rear housing. See Rear Housing


Removal in the Repair section for instructions.

5 Reinstall the power cord (cord not shown).

6 Measure the voltage between the bottom sides of


components L7 and L8 on the CPU assembly
using a standard voltmeter. Refer to picture.
• For 110V analyzers, the measured voltage
must be 100/120V +- 10%
• For 220V analyzers, the measured voltage
must be 230V +- 10%

If no voltage, check the power cord and outlet. If the


Test Point Voltage measured voltage is incorrect, replace the CPU
assembly. See CPU Assembly Removal / Installation
Table 1 in the Repair section for instructions.
X1 + 5.00V +– 0.15V
X4 + 28.00V +– 3.00V
X5 + 21.00V +– 2.5V DC Power Verification
X6 - 21.00V +– 2.5V 1 Remove the rear housing. See Rear Housing
Removal in the Repair section for instructions.
X7 + 5.00V +– 0.25V
X8 GND Reference 2 Connect the power cord to an electrical outlet,
then to the AC power cord socket.
X9 - 12.00V +– 0.25V
X10 + 12.00V +– 0.25V 3 Connect the reference side of the voltmeter to X8
on the CPU board.
Table 2

X2 GND Reference 4 Verify the voltage at each test point listed in Table 1.
X3 + 8.5V +– 1.00V 5 Connect the reference side of the voltmeter to X2
Table 3 on the CPU board.
TP9 GND Reference 6 Verify the voltage at each test point listed in Table 2.
TP10 + 2.000V +– .003V
7 Connect the reference side of the voltmeter to TP9
TP12 - 15.00V +– 0.25V on the pre-amp PC board.
TP13 - 5.00V +– 0.25V
8 Verify the voltage at each test point listed in Table 3.
TP14 + 5.00 +– 0.25V
TP15 + 15.00V +– 0.25V
★ No adjustments are permitted. Failed boards
should be replaced. See CPU Assembly
Removal / Installation in the Repair section for
instructions.
9
T R O U B L E S H O O T I N G G

Display Assembly Verification

For blank display, or faulty keypad operation,


proceed as follows:

1 Remove the power cord from the AC power cord


socket.

2 Remove the rear housing. See Rear Housing


Removal in the Repair section for instructions.

3 Disconnect and reinstall the display cable to the


CPU P4 connector. See Display Assembly
Removal / Installation in the Repair section for
instructions.

4 Reinstall the power cord. If the display now


functions, install the rear housing and resume
normal operation. See Rear Housing Installation in
the Repair section for instructions. If the display or
keypad remain faulty, proceed with step 5.

5 Remove the power cord from the AC power cord


socket. Connect a good “test” display assembly
to the CPU assembly. Reinstall the power cord.

If the “test” display functions properly, the original


display is defective. Replace with a new display
assembly.

If the “test” display does not function, the CPU is


defective. Install a new CPU assembly.

See CPU Assembly Removal / Installation in the


Repair section for instructions.

10
T R O U B L E S H O O T I N G

Flash Device Verification


If the Flash Device is not completely inserted into
position U3 on the CPU, the Rapidchem display
assembly will remain blank on power up, and the
analyzer will appear “off”. Inspect the insertion.
Verify that it is properly installed by pressing on the
device with your thumb.

If it is necessary to inspect the Flash Device itself,


remove the Flash Device with the removal tool by
prying each corner of the Flash Device until it can be
removed by hand. Inspect the Flash Device’s metal
connectors. They should appear curled and separated
from each other. If any of the connectors appear bent,
gently straighten them. If the Flash Device is
permanently damaged, contact your Rapidchem
dealer.

Reinstall the Flash Device into the U3 position with the


chamfered edge in the lower right corner. Incorrect
Flash Device orientation may damage the Flash
Device and/or socket.

11
T R O U B L E S H O O T I N G G

Printer Verification
If the printer is not actively printing:

▲ Verify that the printer paper is correctly installed.

1 Proceed to the SETUP MENU?. USER SETUP MENU?


OPTIONS? is displayed. Press NO. Press YES
to CONFIGURATION?and PRINTER yes
STATUS?.Confirm that the printer is ON by
pressing YES or NO to the displayed message. USER OPTIONS?
Confirm that the paper is threaded properly.
2 Press 9 on the keypad. The printer head should no
move across the paper. If the printer head moves,
CONFIGURATION?
resume normal operation. If the printer head does
not move, proceed to Step 3.
yes
3 Remove the power cord from the AC power cord
socket, wait 10 seconds, then reinstall the power PRINTER STATUS?
cord. If the printer is still not functioning, remove
the power cord and the rear housing, then yes
remove the printer assembly. Inspect for paper
jams or obstructions in the printer head area. See
Rear Housing Removal and Printer Assembly
Removal in the Repair section for instructions.

4 Reinstall the printer assembly. See Printer


Assembly Installation in the Repair section for
instructions. Confirm that the printer cable is
completely inserted into the P3 connector on the
CPU. Reinstall the power cord. If the printer fails
to print, install a known working “test” printer
assembly in the analyzer.

If the test printer assembly works, install a new printer


assembly in the analyzer.

If the test printer assembly fails, the CPU is defective.


Install a new CPU assembly. See CPU Assembly
Removal / Installation in the Repair section for
instructions.

12
T R O U B L E S H O O T I N G

Pump Verification

DIAGNOSTICS?
For suspected pump problems, proceed to PUMP
TEST?. under TEST COMPONENTS? in the
DIAGNOSTICS? section of the SECOND
yes MENU. Press YES. The screen displays
ROTATING.... Look for pump rotation. When
TEST COMPONENTS?
full pump rotation occurs, FULL ROTATION? is
displayed. Press YES and PASS is displayed.
yes
When there is no pump movement or partial pump
PUMP TEST?
movement, press NO and FAIL is displayed.
Remove the pump tubing and repeat the PUMP
yes TEST?. If the test passes, install a new pump
tubing and resume operation. If the test fails, install a
new pump assembly. See Pump Assembly Removal /
Installation in the Repair section for instructions.

Valve Verification

For suspected valve problems, proceed to the


DIAGNOSTICS? VALVE TEST? under TEST
COMPONENTS? in the DIAGNOSTICS?
yes section of the SECOND MENU? Press YES. The
screen displays ROTATING..., then FULL
TEST COMPONENTS? ROTATION?. Look for rotation of the valve knob
and press YES or NO. When full valve knob rotation
yes occurs, press YES and TESTING... is displayed.
Internal testing verifies correct valve positioning for the
PUMP TEST? Cal A, Cal B, Rinse, Air and Home positions. PASS
or FAIL is displayed.
no
When there is no valve knob movement or partial
VALVE TEST?
valve knob movement, press NO and FAIL is
displayed. Repeat the VALVE TEST? If the test
yes fails again, install a new valve module. See
Rapidchem Operator’s Manual for valve module
replacement instructions.

13
T R O U B L E S H O O T I N G G

Sensor Signal Input Verification


Rapidchem sensors that report out of range voltages
may be defective and require replacement. Sensor
troubleshooting is discussed in the Rapidchem Oper-
ator’s Manual. If the Rapidchem analyzer reports
repeated sensor voltage errors, follow this
procedure.

1 Remove the Rapidchem sensors from the sensor


module and check for any fluid leakage around
the sensors and their pins. Examine the contact
housing connectors for any corrosion. All of
these surfaces must be completely dry and salt
free. Reinstall the sensors and attempt
recalibration. If the voltage problems continue,
it is likely that a defect exists in the amplifier
section of the CPU assembly, or the contact
housing is defective.

2 Remove the rear housing. See Rear Housing


Removal in the Repair section for instructions.

3 Install a new pre-amp PC board. See Pre-amp PC


Board/Contact Housing Removal / Installation in
the Repair section for instructions.

14
T R O U B L E S H O O T I N G

Serial Communication Verification


1 Using a Rapidchem serial cable, connect the
analyzer to a device with a known working serial
port.

2 Refer to the serial interface specifications on this


page.

3 When correctly linked, the data that is on the


external device should match the data on the
printout.

▲ See Rapidchem Operator's Manual for Computer


Connection setup.

▲ The data is always sent to the port on the rear of the


analyzer at a baud rate of 2400 bps. The bit
configuration is 8 data bits, 1 stop bit, no parity. If
the data is not being transmitted, the CPU board will
need to be replaced.

Serial Interface Specifications

Connector 25 or 9 pin or a D-sub male or both


Pin Type RS-232
Pin Assignments:
Pin 1 Chassis, Not connected
Pin 2 TxD
Pin 3 RxD
Pin 4 RTS
Pin 5 CTS
Pin 7 Signal Ground
Transmission Rate 2400 bits per second
Bit Configuration 8 data bits, 1 stop
Bit Parity None
Control Codes None
All lines end with carriage return line feed (CRLF)
All transmission is ASCII string

15
RR EE PP A
A II RR RR

Repair Overview
To replace Rapidchem assemblies, disassemble the STORED
INFORMATION?
analyzer in the order described in this section, PATIENT yes
referring to the photographs for assistance. After RESULTS?

rear housing removal, the printer assembly and no QC RESULTS?

display assembly can be removed without removing no


CALIBRATION
DATA?
the CPU. Access to all other assemblies requires no
removing the CPU board. REAGENT MODULE
STATUS?
no
Before performing major repairs, proceed to PRINT SETUP?
PRINT SETUP? under STORED
INFORMATION? in the SECOND yes

MENU?and print the following settings:

USER OPTIONS?,
CONFIGURATION?,
PATIENT LIMITS?,
PATIENT INFORMATION?

▲ Quality control data will be lost if the CPU


board is changed.

Required Tools
Only 4 tools are required to remove or install the
Rapidchem electronic and mechanical assemblies:

• Phillips screwdriver, #2 magnetic


• Phillips screwdriver, #1
• Needle nose pliers
• Flash Device Removal Tool (provided with EPROM
updates)

16
R E P A I R

Rear Housing Removal


Cut the printer paper to separate it from the analyzer
and remove paper. Remove the 5 screws from the rear
housing.
Pull back the rear housing.

Rear Housing Installation


Align the rear housing with the front housing. Verify
that all cables are enclosed inside the housings. Insert
and tighten the 5 screws into the rear housing. Do not
over tighten.

Reinstall the printer paper.

17
R E P A I R R

Printer Assembly Removal


Disconnect the P1 connector from the CPU assembly.

Slide the printer assembly out of the housing tracks.


Avoid pinching the flex cable under the housing.

Printer Assembly Installation


Slide the printer assembly into the front housing cavity,
using a thin, flat object (e.g., business card) to guide
the printer flex cable under the housing. Avoid
pinching the cable.

Insert the printer cable into the P1 connector on the


CPU as shown above.

18
R E P A I R

Display Assembly Removal


The reagent module, sensor module, valve module,
and printer assembly must be removed before
removing the display assembly.

Disconnect the P2 connector from the CPU assembly.

Remove the 4 screws that run along


the top of the rear surface of the front housing.

After screw removal, grasp the display assembly as


shown and gently lift up and away from the front
housing, guiding the ribbon cable through the open-
ing in the front housing.

Display Assembly Installation


Insert the display cable through the rectangular
window in the front housing.

Align the display assembly insertion hooks with the


openings in the front housing. Push the assembly
against the front housing until it locks. Enclose the top
access door post under the upper right corner of the
display housing.

Reinstall 4 screws along the top surface of the front


housing. Insert the display cable through the opening
and attach the display cable to the P2 connector on
the CPU assembly.

19
R E P A I R R

CPU Assembly Removal Printer


Assembly

★ Before replacing the CPU assembly, you must


obtain a replacement that has been factory
programmed specifically for that analyzer. Each
CPU assembly has to be a special order, custom P5 P1 P2
programmed with the analyzer serial number.
Contact your service representative and provide
them with the analyzer serial number. P13

Remove the printer assembly before removing CPU


assembly. Disconnect cables at CPU positions P1, P2,
P5, P7, P6 and P13. P7 P6

Remove the screw in the center of the CPU (P15),


while supporting the transformer. Carefully slide the
CPU assembly off the 4 corner mounting posts and the
pre-amp PC board.

CPU Assembly Installation


Carefully line up the four corner mounting holes on
the CPU assembly with the mounting posts on the front
housing. Gently push in the CPU assembly, making the
connection between the pre-amp PC board and CPU
assembly.

Secure CPU assembly to front housing with mounting


screw at P15.

20
R E P A I R

Flash Device Removal

★ Before changing the flash device on the Rapidchem, follow these steps:

(Faliure to follow these steps will result in analyzer malfunction.)

STANDBY? Press yes

STANDBY IN 1 MIN. Press yes, yes, yes, 9, yes, yes

SERVICE MENU? Press yes

PROG. DOWNLOAD? Press no

LOADER DOWNLOAD? Press no

REPLACE PRE-AMP? Press no

REPLACE FLASH? Press yes

PLEASE CONFIRM! Press yes

POWER DOWN NOW Disconnect power

Remove the flash device with the removal tool by


prying each corner of the flash device until it can be
removed by hand.

Flash Device Installation


Install the flash device into the U3 position with the
chamfered edge in the lower right corner. Incorrect
flash device orientation may damage the flash device
and/or socket.

21
R E P A I R R

★ After changing the flash device on the Rapidchem, power up and follow
these steps:

STANDBY? Press yes

STANDBY IN 1 MIN. Press yes, yes, yes, yes, yes

QC MENU? Press yes

UNIT SETTINGS? Press no

CLEAR MEMORY? Press yes

PLEASE CONFIRM! Press yes

22
R E P A I R

Access Door Removal


Remove the CPU assembly and loosen the top left
screw on the rear of the analyzer.

Lift the right corner of the display assembly to


disengage the access door post. Lift the door to
remove the bottom post.

Access Door Installation


Insert the bottom door post into the front housing
base. Lift the right corner of the display assembly and
insert the access door post. Tighten the screw on the
rear of the front housing.

23
R E P A I R R

▲ In order to properly transfer data stored from the


existing pre-amp PCB to a new pre-amp PCB, it is
necessary to follow the steps listed in the chart
below. (Failure to follow these steps will result in a
“MISMATCH ERROR” on the printout.)

★ Before changing the Pre-amp PC board on the Rapidchem, follow these steps:

STANDBY? Press yes

STANDBY IN 1 MIN. Press yes, yes, yes, 9, yes, yes

SERVICE MENU? Press yes

PROG. DOWNLOAD? Press no

LOADER DOWNLOAD? Press no

REPLACE PRE-AMP? Press yes

PLEASE CONFIRM! Press yes

POWER DOWN NOW Disconnect power

Pre-amp PC Board/Contact
Housing Removal
Remove the screw which connects the grounding strap
to the pre-amp PC board.

Remove the 6 screws from the pre-amp PC board.

Remove the pre-amp PC board with the contact hous-


ing attached from the front housing. The contact
housing can be removed from the pre-amp PC board
by gripping both sides and pulling apart.

24
R E P A I R

★ After changing the Pre-amp PC board on the Rapidchem power up and follow
these steps:

STANDBY? Press yes

STANDBY IN 1 MIN. Press yes, yes, yes, yes, yes

QC MENU? Press yes

UNIT SETTINGS? Press no

CLEAR MEMORY? Press yes

PLEASE CONFIRM! Press yes

Pre-amp PC Board/Contact
Housing Installation
Align the opening on the pre-amp PC board with the
CPU board mounting post. This will align the screw
holes. Insert the 6 screws to secure. Do not
overtighten. Connect the grounding strap to the pre-
amp PC board.

25
R E P A I R R

Valve Cable Removal


Remove the retaining clips securing the valve cable
with needle nose pliers.

Caution: DO NOT damage the posts.

By squeezing the retaining clips with the pliers, the


clips should lift off the posts.

Remove the valve cable from the front housing.

Valve Cable Installation


Insert the valve cable into the back side of the front
housing so that the ribbon cable is positioned on the
left side of the connector.

Install 2 new retaining clips (top and bottom) on the


cable posts to secure the connector. Push clips on
using needle nose pliers.

26
R E P A I R

Pump Assembly Removal


Remove the CPU assembly before removing the pump
assembly. Using a #1 Phillips, remove the 2 screws
and washers from the front side of the front housing.

Remove the screws which connect the grounding strap


to the pre-amp PC board and the pump assembly.
Place the grounding strap aside. Slide the pump as-
sembly through the back side of the front housing.

Pump Assembly Installation


Insert the pump through the backside of the front
housing. Align the pump bracket holes with the 2
mounting posts on the front housing so that the pump
motor cable is positioned below the pump assembly.

While holding the pump assembly in position, insert


the 2 screws with washers through the front side of the
front housing to secure the pump in position.

Attach the grounding strap to the pump assembly and


the pre-amp PC board.

27
R E P A I R R

Sampler Removal
If the sampler requires replacement, it can be
removed from the sensor module. Using a coin or
fingers, remove the retaining screw from the sensor
module.

▲ Also refer to package insert for sampler removal


and installation updates.

Remove the screw mount (includes spring).

Rotate the sampler into the capillary position, then pull


it out of the sensor module.

Sampler Installation
Install the new sampler (includes sample probe and
wiper) in the sensor module. Insert the sampler
alignment pin into the sensor module. Rotate the
sampler into the closed position.

Install the screw mount (includes spring) into the


sampler. Replace the retaining screw and tighten.

▲ Do not overtighten the retaining screw.

28
R E P A I R

Software Upgrade Kit


This kit includes a 3.5” Floppy Disk and a serial
cable.
Analyzer Setup
Using the serial cable, connect to the PC serial port.
Connect the telephone jack side of the cable to the
barcode port on the rear panel of the Rapidchem.

Store files provided by Bayer (*.hex and *.key) in a


convenient directory. The name of the hex file is the
CRC number used to validate the successful update of
the program.

PC Setup
Open Hyper Terminal under Programs > Accessories
> Communications.

Enter a new connection name and click OK. Select


Direct to Com 1 at Connect Using and click OK.

Change to 4800 bits per second, 8 Data Bits, Parity


NONE, Stop Bit 1, and Flow Control Xon/Xoff.

Click at Advanced, uncheck Use FIFO Buffer, and


press OK twice.

Click at File, then select Properties to confirm all


settings that selections above are correct.

Select File, then Save As, and enter a new file name.

Load New User Program

Open Hyper Terminal with your new hyper terminal


file.

Turn analyzer on. Select STANDBY? under


SECOND MENU?

When the STANDBY IN 1 MIN. message is


blinking, press yes three times, press 9 once, then
press yes twice.
SERVICE MENU? is displayed. Press yes.

Press yes to PROG. DOWNLOAD? and yes to


CONFIRM!

When the message POWER DOWN/UP


appears, turn the analyzer off, then turn back on
after 3 seconds.

The analyzer will display LOAD NEW


PROGRAM - CONFIRM? Press yes. SEND
<X.KEY> NOW is displayed. The analyzer is
ready to receive data.

29
R E P A I R R

▲ At this time, you have approximately one minute to


begin the download. If a timeout occurs, the analyzer
returns to the LOAD NEW PROGRAM message.
By answering no to this and yes to GO BACK TO
OLD PROGRAM, the user can discontinue the
download process.

Select Send Text file under transfer menu from the tool
bar in Hyper Terminal windows.

Browse to the director which stores *.key and .hex


files. Select the .key file, then click at OPEN. The
analyzer displays Erasing Flash... and then displays
SEND <.HEX> FILE. Go to Send Text file
again. Select Total.hex file, then click at OPEN. The
analyzer should display a RECEIVING
FILE... message. This process will take
approximately 7-12 minutes.

▲ Responses are required during file transfers.

When DOWNLOAD FINISH is displayed, press


yes. The display should show CRC CORRECT?
Confirm the number printed is the same as the name
of the hex file and answer yes. If the numbers do not
agree, answer no. Restart program and repeat the
download steps. If numbers still do not match, contact
your Bayer representative.

When all steps are complete, the analyzer will reset


itself. Upon restarting, the analyzer is running with
new revision software.

30
R EO P T AE I S R
N
+12V
X1
L1
1 2
U1 VCC
BEAD C4
3 1
IN OUT
Y1

C1
C2

22pF
.1uF

GND
C5

2
MIC2950
12MHz
1

2.2uF-16V
35
VCC
VCC
AGND
VCC
GND

XTAL1
38

AVREF-
VBATT EA
RESET 46 A15 46 29 D0
RESET P27-A15 PA0
45 A14 45 28 D1
EW P26-A14 PA1
A13

2
P25-A13 PA2
BUB_TOP 1 A12 D3
P50-ADC0 P24-A12 PA3

C6
U4 BUB_BOT 68 A11 D4

2
P23-A11

U6A
TEMP1 P52-ADC2 P22-A10 A10 A10 PA5 D5
TEMP2 P53-ADC3 A9 A9 PA6 D6
1 TEMP3 A8 D7
P20-A8

VCC
BAT/AC 64 PSD834F
P55-ADC5
4 7 PROB_OUT 63 AD7 37 7 SERIAL_E
PFI /RST P56-ADC6 AD7-A7 PB0
PROB_HM 62 50 AD6 36 6
P07-AD7
8 6 AD5 RTS
VBAT WDI P06-AD6 AD5-A5 PB2
P05-AD5 AD4 AD4-A4 PB3 HEATER2
5 RAM_ENA

GND
PACK_RD

1
PFO P04-AD4 AD3-A3 PB4
3VBAT AD_CLK P11-CT1I P03-AD3 AD2 AD2-A2 PB5 LATCH
AD_WR AD1

3
P12-CT2I P02-AD2 AD1-A1 PB6

+
P13-CT3I P01-AD1 AD0 AD0-A0 PB7
AD_RD 57
P14-T2 P00-AD0
PACK_PRG U3 20 JTAG_T
P15-RT2 PC0

B1
3V LITH

-
EE_DATA P16-SCL CPU-ALE ALE-PD0 PC1
PUMP_STP 23 48 CPU-PSEN PC_2
P17-SDA ALE PSEN PC2
CPU-RD JTAG_T
CPU-PSEN 47
PSEN CPU-WR WR PC4
PHASE1 7 48
P40-CSR0 /RST RESET PC5
PHASE2 8
VALVE_EN 9 RTC_SEL 11 JTAG_JEN
P42-CSR2 PC7 P8:1
PUMP_EN 10 30
P43-CSR3 P36-WR RAM_SEL
11
PC_2 29
GND
GND

DISP_REG P45-CSR5 P35-T1 CAPI_MOD /RST P8:8


3VBAT DISP_R/W 28 VALVE_HM
P46-CMT0 P34-T0
DISP_EN
1

P47-CMT1 P33-INT1
26

P32-INT0 PRNT
T
P30-RXD R
VCC C64 VCC
C8

JTAG_JEN
.1uF

GND
.1uF JTAG_TST
74HC14 80C552AZ VCC
JTAG_TDI
HEAT_PWM
U6P DGND JTAG_TCK
14 7 JTAG_TDO
VCC GND
JTAG_TER

NAME
DGND

2 PRINTER, DISPLAY, RTC


3 SERIAL DATA #1 U6B
4 SERIAL DATA #2 Z1
3 4 1
S
2
S C H E MR A

5 STEPPER DRIVERS BUZZER G PKM22EP


6 BUB DET. & HEATER 1 74HC14
7 HEATER 2 & TEMP SENSORS JTAG PORT & CPU
E PT A

8 BUTTON RD & PREAMP CONN DGND

9 POWER SUPPLY
I CI R
S

PWM HEAT & EXT. RAM


R

A
VCC

/RST P1::19
PRNT_RDY P1::6
VBATT
PRNT_STB

P1::10
.1uF P1::12

D7
C11 D6
D5
D4 P1::7

D2
D1
D0
U7

18
AD3 11 /RST
D3
AD2 12 15
D2 CS1

VCC
AD1 13
AD0 14
D0
1
A3 NC P2::11
6
5
A1
4
A0
9
GND

RTC-62421
CPU-ALE ALE P2::1
8 VCC
/RD P2::2

CS0
/WR

2
P2::18
DISP_EN P2::17
DISP_REG
RTC_SEL DISP_R/W
DIS_ADJ
DISP_SL1
/RST P2::24

CPU-RD

CPU-WR
GND
P2::12
P2::14

DGND

DGND

PRINTER, DISPLAY PORT & RTC

B
T1
3 4

2 5

1 6

ISOXFMR

VCC
U12
4
1

6
1uF

2
5
4N26N
DGND U10

14
U11 1 NC P3:1
U13
TXD 4 4
TXD

VCC
2 1 3
AC

D1 T1DIN P3:4
/RTS 5 12
RTS TXD
D2 T2DIN
RXD1 9 6 11
RXD RTS P3:5
5
CTS 12 10
CTS RXD
3 2 6
T1LDR R2LDR P3:2
5
6 4N26N 9
SERIAL_E T2LDR CTS
8 7
EN BYP P3:3
10 13
R1DIN V-
1 8
11 5 4N26N 2 ISO_V+
R2DIN V+ P3:6
7 2 14
GND RGND

MAX250 MAX251
6
C13

DGND
1uF
C14

4.7uF

1
4

U14

5 4N26N
2

1
4
DGND
U15
REMOTE-GND

R3 SERIAL DATA PORT #1


1M

C9

.1uf

C
X3

ISO_V+

C16
X2

10uF-16V
/RTS
U6D

RTS 9 8 1
REMOTE-GND
NC P4:1 VCC
74HC14 2

PS2505
P4:5
C17

R5

R4
P4:2
VCC
DGND

NC P4:4 RXD1 2 4 RXD


RXD2 1B
REMOTE-GND 5 7
74HC14 2Y
6
RXD2 11 9
10 11 3 2 3A 3Y
NC P4:3 10
3B
12
4A 4Y
13
U6E 4 4B

2.21K P4:6 LATCH 1


A\/B
15
GND

G
8

D2
74HC157

DGND

REMOTE-GND

SERIAL DATA PORT #2

D
+24V-FUS
VCC

22uF-50V

.001uF
C19 U8
DGND
9
I12
DGND
I02
17
I11
VALVE_EN 20 3
I01
23
PHASE2 P2
PHASE1 16
P1 SEN1
VREF2
RC2 VREF1
14
RC1
5
13
LS 2A
1B
24

C24
S 1A

.001uF
R15
UDN2916B

C20
.001uF
DGND
DGND

VALVE

P6:4
P6:5
P6:8
P6:7
+24V-FUS

U20
2
VSUP1
16
VCC
VCC

7
VSUP2
15 PUMP_EN
PSA EN
OUT-A PUMP_STP
11
PSB STEPS
3
C25

OUT-B
14
PSC DIR
6
OUT-C
PSD HALF
8
OUT-D
9
PHASE
.1uF

DGND

STEPPER MOTOR DRIVERS

UCN5804B

DGND DGND

PUMP
P7:1

P7:6
P7:5
P7:4
P7:3
P7:2

E
P5:13 CAPI_MOD

P5:10 PROB_HM

P5:12 PROB_OUT
VCC
P5:11 MOD_DOOR

5.6v znr
5.6v znr
5.6v znr
5.6v znr
R16
U19A
1M 2
+5V
1 BUB_BOT
P5:6

R17
1M
3

.01uf
DGND
P5:7 TLC2272A

P5:9
AGND

8
R18

VANA+
1M U19B BUB_TOP
6

.1uF

U19PB
TLC2272A
7
1M

GND
.01uf

4
HEATPWM +5V
TLC2272A
DGND

AGND AGND
HEAT_PWM
R21 HEATCON

W1
C30

P5:2
.1uF

U9C
P5:4
.1uF 9
P5:1
8
P5:14
P5:5 C31
R27 10
AGND
HEAT_DAC TLC2274A

U9B
AGND 6

C32
.1uF
7 TEMP1
5

TLC2274A
BUBBLE DETECTOR & HEATER #1
R25 R26
+5V

AGND

F
VALVE_HM

12
VCC

U6F
74HC14
VCC

13
P6:11

VALVE P6:13

R34
U27

5.6V znr
U9A
1 2 2
IN OUT
1

GND
TEMP3
3

C34
LM35 +5V
TLC2274A
L3
1 2
BEAD
+24V .1uF
DGND
R37
4

9.09K
VANA+

Q2
.1uF

W2
RXE075
U9PB
TLC2274A

HEATER2
GND

F15N05L

R29
11

P6:14
P6:12
DGND
R33

AGND

U9D
DGND

R30
13

14 TEMP2
12

TLC2274A
HEATER 2 & TEMP SENSORS

R31 R32
+5V

AGND

G
VCC
+12V

-18V
P9:9
+18V D14
P9:7
AD_WR
P9:3
AD_RD
P9:2
AD_CLK
P9:1
ADC_ENA

Q6
P9:5
VP0300L
EE_DATA

2N7000
P9:6
PACK_RD P13:1
GND
P9:4
AGND Q5 Q4
P9:8 P13:2

PACK_PRG
C71
D13

2N7000
DGND AGND

DGND

BUTTON READER & PREAMP CONNECTOR

H
-12V +12V

X9 X10
C53
U24 U23

2 3 1
IN OUT IN OUT

GND
GND
C40

.1uf
X5 ENTRY MO

1
2
79L12 78L12
7 GND-EARTH

5
6

A1
+18V
DGND 1 2

L8
AC-CHOKE
L7

X6
C60

L9

C54
3
4

+24V
+24V-FUS
X4
-18V P15
JUMPER

1000uF 35V
1
2

MNT-HOLE
AC MAINS
W8
GND-EARTH GND-EARTH
THROUGH HOLE PAD

C55
RXE075 TO SHIELD OF CHASSIS
S1

ON \ OFF
VCC 12 6
X7
11
3
4

4 S2

9 3
3 4
110/220
N1 8
U30 2 1

4
L5
7 1
2 1
VOUT VIN 63SPS

FB
100uh XFMR56VA

1N5819

GND
ON

C59
.1uF

D17
3
5
L4

4700uF 10V
3300uF 35V
1 2
BEAD
X8
BAT/AC
AGND
DGND DGND

+18V

P14:6 NC POWER SUPPLY

BATTERY

GND-EARTH

I
U22A
2

1 VCC
3
C46
OPA2131P VBATT
+24V
.1uf

C47
28

U21

4
L6 .1uf A14
2 1 A13 DGND
VCC

HEATPWM VOUT VIN A12

FB
100uh

A10

GND
ON
A9

20
U28
LM2575ADJ

3
5

1N5820
AD7 19 A7 3 HM62256B
VCC

C37
AD5 A5
AD4 A4

AD2 A2

330uf 35v
AD1 A1
8D 8Q A0 A0
+12V U26 19
I/O8
CPU-ALE
C
DGND 1
GND

DGND
10
GND

I/O1
14

DGND
8 4
VANA+ VANA-
HEATCON R41 R40
U22PA CPU-WR

DGND
6

7
-12V
RAM_ENA

-1.25V
Q1 5

OPA2131P

CPU-RD
DGND

-12V PWM HEATING & EXT. RAM

J
Contacting Bayer Diagnostics
For technical assistance, contact your local authorized representative. For customer service or
additional information, contact your local authorized distributor.

Addresses and Communication Numbers

Manufactured for: Bayer Inc.


Bayer Corporation Bayer Diagnostics
333 Coney Street Healthcare Division
East Walpole, MA 02032-1597 77 Belfield Road
USA Toronto, Ontario
508 668-5000 Canada M9W 1G6
416 248-0771
Bayer Argentina S.A.
División Diagnósticos Bayer S.A.
Ricardo Gutiérrez 3652 División Diagnóstica
B1605EHD Munro - Buenos Aires A.A. 80387
Argentina Av. de las Américas No 57-52
54 11 4 762 7000 Santafé de Bogotá, D.C. – Colombia
(571) 4234199-4234352
Bayer Australia Limited
Diagnostics Business Group Bayer A/S
2 Keith Campbell Court Nørgaardsvej 32
Scoresby Victoria 3179 Australia DK-2800 Lyngby, Denmark
1 800 034 477 + 45 45 23 50 00

Bayer Austria GesmbH Bayer OY


Geschäftsbereich Diagnostika Suomalaistentie 7
Lerchenfelder Gürtel 9-11 FIN 02270 Espoo, Finland
A-1164 Wien, Austria + 35 89 88 78 87
43 - 1- 71146 - 2411
Bayer Diagnostics
Bayer s.a.-n.v. Tour Horizon
Division Diagnostics 52, quai de Dion Bouton
Avenue Louise 143 Louizalaan 92807 Puteaux Cedex, France
1050 Bruxelles-Brussel, 01 49 06 56 00
Belgium
32 2 535 66 81 Bayer Vital GmbH & Co. KG
Geschäftsbereich Diagnostics
Bayer S.A. Siemensstraße 3
Produtos Diagnósticos D-35463 Fernwald, Germany
Rua Domingos Jorge 1100 0049-(0)641-4003-0
04779-900 - São Paulo - SP
Brazil Bayer Hellas S.A.
55 11 5694 5574 Akakion 54A
Marousi
Athens 151 25, Greece
01 -68 83 648

K
Bayer Diagnostics Limited Bayer As
20/F Gee Chang Hong Centre Brennaveien 18
65 Wong Chuk Hang Road N-1483 Skytta, Norway
Hong Kong + 47 67 06 86 00
852-28147337
Bayer Sp. z o.o.
Bayer Diagnostics India Limited Al. Jerozolimskie 158
589, Sayajipura 02-326 Warszawa, Polska
Ajwa Road +48(0)225723500
Baroda – 390019
Gujarat, India Bayer Portugal S.A.
91 265 46 2720 Divisao PH / DS
Rua da Quinta do Pinheiro, 5
Bayer S.p.A. 2795-653 Carnaxide, Portugal
Divisione Diagnostici 351.21.416.50.22
Via Grosio 10/4
20151 Milano, Italia Bayer Puerto Rico Inc.
+39/023978.1 Diagnostics Division
Victoria Industrial Park
Bayer Medical Ltd. Building #1
Unosawa Tokyu Building 3F Carolina, Puerto Rico
1-19-15, Ebisu 787 752-8989
Shibuya-Ku
Tokyo 150-0013, Japan Bayer (Pty) Ltd.
81.3.3440.4881 Healthcare Division
27 Wrench Road
Bayer Diagnostics Korea Limited Isando 1600, South Africa
4/F Kyemyung Building 27 11 921-5048
48-7 Myungil-Dong
Kangdong-Ku Química Farmacéutica Bayer, S.A.
Seoul, Korea 134-070 División Diagnósticos
82-2-428-5980 Calabria, 268
08029 Barcelona, España
Bayer de México, S.A. de C.V. + 34 93 495.65.00
Division Diagnósticos
Ave. Colonia del Valle No. 615 Bayer AB
Col. del Valle Drakegatan 1
Delegación Benito Juárez S-402 24 Göteborg, Sweden
México, D.F. C.P. 03100 + 46 31 83 98 00
525 7283301
Bayer (Schweiz) AG
Bayer B.V. Geschäftsbereich Diagnostika
Division Diagnostics Grubenstrasse 6
Energieweg 1 8045 Zuerich, Switzerland
3641 RT Mijdrecht, The Netherlands 0041/1/465 81 11
+31 (0)297 280 666

M
Bayer Taiwan Company Limited
Diagnostics Division
8/F No. 109 Sec. 2
Keelung Road
Taipei, Taiwan R.O.C.
886-2-23777520

Bayer plc
Diagnostics Division
Bayer House
Strawberry Hill
Newbury, RG14 1JA
United Kingdom
+44 (0)1635 563000

Bayer Corporation
Diagnostics Division
511 Benedict Avenue
Tarrytown, NY 10591-5097 USA
914 631-8000

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005521-001 R0

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