How Machine Learning is used to

find the COVID-19 Vaccine

Coronavirus is a newly declared virus that has caused the outbreak of

respiratory illness that is given the name of COVID-19 which was first
initiated and diagnosed in China. As per the statistics given
by worldmeters, there are 145,384+ infected cases around the
world with 5,416 deaths and 70,936 recovered cases of COVID-19.
More than 35 countries over the globe have been affected by
evacuations taking place to protect foreign nationals from the virus.
Major countries like China, Japan, HongKong, Philippines, USA, etc.
have been reported deaths each respectively. Stats are still fluctuating!
As per the information provided by various resources COVID-19 may be
passed from person to person. Community spread has been seen which
means people have been infected with the virus in a particular area
including people who are unsure how and where they have been
affected. People throughout China have been affected including over
100 countries. On January 30, 2020, the WHO declared the COVID-19
outbreak a public health emergency. The primary symptoms include-
cough, fever, and shortness of breath.

How does Machine Learning use to find any virus

vaccine?
Those who are taking remedial measures in order to stay away from
the COVID-19 are required to need a CT scan and AI is helping to speed
up the diagnosis reducing the time from 5-minutes to 20 seconds.
Machine Learning can be valued in the healthcare industry with the
ability to process huge datasets above the scope of the capability of
humans and the algorithms are converted into insights that aid
physicians in planning and providing care to get satisfactory treatment.
Computer-Aided Drug Design (CADD) has been come out as a method
for developing candidate drugs for the treatment of many types of
diseases. The discovery of drugs and developing a new drug is a very
long-term process and very costly, that is why the CADD approach is
used in pharmaceutical companies to resolve this issue to some extent.
It is a computational approach to discover developed, enhances and
analyzes drug and biologically related active compounds. This approach
is used for virtual screening, virtual library design, lead optimization and
used for quick evaluation of large compounds to guide and speed up
the development of the new active biological compound.
As the virus has raced around the world, more than 350 genome
sequences have been detected, as shared by GISAID, an online
platform. The 3D design of Genome protein has been released. Various
Biotech companies of China have been gearing up to repurpose existing
drugs as treatment for the coronavirus outbreak in Wuhan.
The Ethics of using Machine Learning in Healthcare

Let us understand the concept by taking an example of the deadliest

pandemic of coronavirus. Machine Learning algorithms may help in
detecting the severity of coronavirus in patients having the doubt of
this deadly disease.
Google's DeepMind division utilized its most recent AI calculations and
its registering capacity to comprehend the proteins that may make up
the infection, and distributed the discoveries to help other people
create medications. BenevolentAI utilizes AI frameworks to assemble
drugs that can battle the world's hardest maladies and is currently
helping help the endeavors to treat coronavirus, the first run through
the organization concentrated its item on irresistible sicknesses. Inside
long stretches of the flare-up, it utilized its prescient abilities to propose
existing medications that may be helpful.

How Machine Learning is used to find the COVID-

19 vaccine?

All Community is trying to find the solution, one of them is Matt

O'Connor, he is data science and strategy coach also founder of
Reboot.ai.
His approach was train the model from scratch so he can get robust and
realistic molecules, He combined data sets from two sources: i) Moses
data set and ii) ChEMBL data set. Together these two data sets
represented about 4 million smiles and it took 4 days just to train the
initial network.

After traning the model result score was <-16.075 and weight <900
daltons, he found one of the existing inhibitors Remdesivir (it was
designed for Ebola virus) has good score, he also found other novel
inhibitors.

Chinese researchers have screened 30 different compounds (a mix of

anti-HIV drugs, an immunosuppressant, an anti-schizophrenia drug, and
also natural products and Chinese traditional medicines), for their
efficacity on 2019-nCoV. According to the Chinese Academy of Sciences
(CAS), three of these molecules have fairly good inhibitory effects:
Remdesivir - initially designed to combat the Ebola virus, developed by
Gilead Sciences. Works as an RNA polymerase inhibitor.
Chloroquine - an antimalaria drug initially discovered by Bayer, later
repurposed as an anti-HIV in clinical trials. The anti-viral mechanism of
action is still unclear to me.
Ritonavir - an anti-HIV drug developed by Abbott (now Abbvie). Works
as a protease inhibitor.
The Chinese researchers are now trying to get approval for a clinical
trial to validate their efficacy on 2019-nCoV in patients.

Computer-based intelligence or simply Artificial Intelligence can spot

designs in information and make expectations, and the expectation is
these instruments could recognize sedate possibilities to test on people
inside months. WHO and governments across the globe are working
round the clock by using technology to fight the outbreak. Though the
virus is spreading but taking precautions will help you stay safe from
the pandemic of Coronavirus.
If you are planing to create something new with ML and need help
contact us, At Valiant Technosoft we have a team of developers which
is an expert in Machine Leaning and AI.
Stay healthy, Stay Safe

Address: A-801 Binori Solitaire, South Bopal, 380058

Ahmadabad, Gujarat, India

Phone No: 9998 989971

Email Id: hello@valianttechnosoft.com
URL: https://valianttechnosoft.com