DCP Complete List

Operational Support & Logistics
Ebola Virus Disease Disease Commodity Packages
Agent's Biosafety Level: BSL4 Ebola Virus Disease [LINK]

Epidemic Potential: Urban - high, Rural -medium Last Update: 21 September 2018 Managing Epidemics Handbook [LINK]
SURVEILLANCE Sample Collection Diagnosis
Polymerase Chain Reaction
Samples collected from patients are an extreme biohazard risk; Rapid Diagnostic Test (RDT) Immunoassay
(PCR)
laboratory testing on non-inactivated samples should be conducted
under maximum biological containment conditions. All biological Blood & Nasopharyngeal samples Several RDTs under WHO 1 test under EUAL
specimens should be packaged using the triple packaging system Several tests under WHO
Emergency Use Assessment & several in-house
when transported nationally and internationally. EUAL
Listing (EUAL) ELISA/IF tests
Note: Many diagnostics supplies are also used for Case Management purposes, but have been included only in Surveillance.
Emergency Use Assessment & Listing [LINK]
Medical Device List. [LINK]
Infection Protection & Control
PREVENTION & CONTROL Travel & Trade Vaccine Post-Exposure
(IPC)
Personal Protective Equipment
On outbreak-specific basis, (PPE) for screening (standard),
Temperature screening at consider: rVSV-EBOV under in health care facilities & safe On outbreak-specific basis, and as
Ebola transmits from person to person through close contact. Strict Expanded access use. Please
airports/entry points of affected and dignified burials per most recent guidance in the R&D
IPC measures with appropriate PPE are key to control outbreaks. refer to SAGE Recommendations
countries Blueprint.
PPE Guidelines
SAGE - EBOLA [LINK] [LINK]
R&D Blueprint [LINK]
CASE MANAGEMENT Treatment Personal Protective Equipment (PPE)

Aetiological Supportive
On outbreak-specific basis, consider:
investigational therapeutics for consideration
Isolated patients must be placed in intensive care and receive PPE for Treatment in Healthcare Facilities for blood-
under Monitored Emergency Use of IV Fluids critical
supportive treatment. Aetiological treatment available only under borne pathogens.
Unregistered and Investigational Interventions Intensive care for isolated patient
compassionate use or research protocol (See PPE Guidelines link)
(MEURI) Pain & Fever
MEURI - EBOLA
[LINK]
Paper
Key outbreak control activities considered for material supply
• Rapid diagnostics tests to improve disease identification

• Investigational antiviral and/or monoclonal antibody under MEURI to reduce mortality
• Supportive treatment (hydration & fever/pain relief) to reduce mortality
• Personal Protective Equipment and material for the establishment of IPC measures in health facilities to reduce transmission
• Personal Protective Equipment and material for the conduct of safe and dignified burials to reduce transmission
Note: Products for Surveillance, Prevention & Control, and Case Management are undergoing rapid and continous development and refinement. For greater clarity, please refer to most recent applicable WHO technical guidance.
INTERVENTION COMMODITY TECHNICAL DESCRIPTION

Guidance on regulations for Transport of Infectious
Triple packaging boxes Triple packaging boxes for transport [LINK]
Substances 2017 - 2018
Viral Transport Medium Medium for specimen to transport to laboratory Interim Guideline [LINK]
Sample Collection
Tubes, blood collection, Vacuum tube used for blood collection with EDTA, sterile, capped with vacuum
EDTA seal. Material: plastic. 4 ml and 6 ml
SURVEILLANCE
Tubes, blood collection, Vacuum tube used for plain/dry blood collection without anticoagulant, sterile,
plain/dry capped with vacuum seal. Material: plastic. 4 ml and 6 ml
Puncture resistant container for collection and disposing of used, disposable and
• WHO performance specification E10/IC.1
Sharps container boxes auto-disable syringes, needles. 5 L capacity accommodating approximately 100
• WHO/UNICEF standard E10/IC.2 or equivalent
syringes. Boxes prominently marked.
Temperature Screening Diagnostics
Criteria for selection of specific diagnostic tests may include historical efficacy, adherence to any existing Target Product Profiles, ease of use, necessary throughput, distribution and
logistics requirements, and manufacturer production capacity. For some pathogens, consideration may need to be given to the presence of mutations in targeted gene sequences or
proteins. WHO can advise on the selection of tests on a case by case basis as determined by a specific event.
• ISO 80601-2-56:2009
• ISO 80601-2-59 Ed. 1.0:2008
• ASTM E1104-98(2003)
Handheld battery-powered electronic instrument designed to estimate body
• ASTM E1965-98(2009)
temperature of a site on skin (e.g. forehead) non-invasively, quickly without
Thermometer, Infrared • ASTM E1112-00(2011)
touching. A sensor can be cleaned easily by each use with wiping by disinfectant
• JIS T 4207:2005
or sterilisable cover.
• or equivalent
WHO Core - Thermometers, electronic, infrared [LINK]
Vaccine rVSV-EBOV. Under Expanded Access use. None approved to date. (Please see SAGE link above)
Vaccine
Temperature required: -80 degrees C. Long term storage. Device is intended to be used as a stationary passive container to store vaccines for a period
Cold Storage Boxes
of minimum 35 days before recharge with icepacks.
OSL | Disease Commodity Packages 1 EBOLA VIRUS DISEASE

Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably

reach mid-forearm (eg. minimum 280mm total length. Sizes, S, M, L • EU standard directive 93/42/EEC Class I, EN 455,
• EU standard directive 89/686/EEC Category III, EN 374,
Gloves,
Outer glove should have long cuffs, reaching well above the wrist, ideally to mid- • ANSI/ISEA 105-2011,
examination
forearm. Inner glove should be worn under the cuff of the gown/coveralls (and • ASTM D6319-10
under any thumb/finger loop) whereas the outer glove should be worn over the • or equivalent
cuff of the gown/coveralls.
Gloves, surgical, nitrile, powder-free, single use.

• EU standard directive 93/42/EEC Class I, EN 455,
Gloves, surgical, length to
PPE - Standard
forearm large (longer than

forearm. Inner glove should be worn under the cuff of the gown/coveralls (and • ASTM 6319-10
examination gloves)
cuff of the gown/coveralls. Sizes 5 to 8.5
Fluid resistant particulate respirator. Surgical N95 respirator or higher "Surgical N95 respirator" cleared by the US FDA and NIOSH, or
Face mask,
High fluid resistance, Good breathability, Internal and external faces should be equivalent
particulate respirator, grade
clearly identified, Structured design that does not collapse against the mouth • Fluid resistant surgical N95 respirator with minimum 80 mm Hg
N95 or higher
(e.g. duckbill, cup-shaped) pressure based on ASTM F1862, ISO 22609 , or equivalent
• Option 1: fluid penetration resistant: EN 13795 high performance, or

Single use, fluid resistant, disposable, length mid-calf to cover the top of the AAMI PB70 level 3 performance or above, or equivalent
Gown boots, light colours preferable to better detect possible contamination, • Option 2: blood borne pathogens penetration resistant: AAMI PB70
thumb/finger loops or elastic cuff to anchor sleeves in place. level 4 performance, or (EN 14126-B) and partial body protection ( EN
13034 or EN 14605), or equivalent
• EU standard directive 89/686/EEC Category III,

• EN 374 (AS/NZS 2161.10.1.2005) chemical resistance for AKL
• EN 374 (AS/NZS 2161.10.1.2005) for biohazards Level 3
Gloves, Covering forearm. Fabric: cotton or polyester, rubber coating, waterproof, and performance, or above
heavy duty acid resistant, minimum cuff length 150mm • EN 388 (AS/NZS 2161.10.3.2005) 3111 for abrasion, blade cut, tear
PREVENTION & CONTROL
and puncture, or above

• EN 420:2004+A1:2009
or equivalent, or above
Face mask,
N95 or higher
Good seal with the skin of the face, Flexible PVC frame to easily fit with all face
contours with even pressure, Enclose eyes and the surrounding areas,
• EU standard directive 86/686/EEC, EN 166/2002,
Accomodate wearers with prescription glasses, Clear plastic lens with fog and
Goggles, • ANSI/ISEA Z87.1-2010,
scratch resistant treatments, Adjustable band to secure firmly so as not to
protective or equivalent
become loose during clinical activity, Indirect venting to avoid fogging, May be re-
usable (provided appropriate arrangements for decontamination are in place) or
disposable.
• Option 1: blood and body fluid penetration resistant: meets or

Single use, light colours preferable to better detect possible contamination,
exceeds ISO 16603 class 3 or above exposure pressure, or equivalent
Coverall thumb/finger loops to anchor sleeves in place, good freedom of movement.
• Option 2: blood-borne pathogens penetration resistant:meets or
Sizes: M, L, XL
Burial Teams
Scrubs, tops Tunic/tops, woven, scrubs, reusable or single use, short sleeved (tunic/tops), worn underneath the coveralls or gown.
Scrubs, pants Trouser/pants, woven, scrubs, reusable or single use, short sleeved (tunic/tops), worn underneath the coveralls or gown
Straight apron with bib,

Fabric: 100% polyester with PVC coating, or 100% PVC, or 100% rubber, or May comply with
Apron, other fluid resistant material, Waterproof, Sewn strap for neck and back fastening • EN ISO 13688:2013
heavy duty, non-woven Minimum basis weight: 300g/m2 • EN 14126-B and partial body protection (EN 13034 or EN 14605)
covering size: 70-90 cm (width) X 120-150cm (height) or equivalent
Reusable (provided appropriate arrangements for decontamination are in place)
Non-slip sole pattern, PVC or polyurethane sole which is completely sealed and waterproof, Knee-high in order be higher than the bottom edge of the
Boot, rubber gown, Range of sizes available to improve comfort and avoid trauma to the feet, Materials of construction include rubber, PVC, neoprene, nitrile,
polyurethane, Favor light colours to better identify possible contaminations.
Disposal bag for bio-hazardous waste, 30x50cm, with "Bio Hazard" print, autoclavable polypropylene.
Bio-hazardous bag
50 or 70 micron thickness

Made of linear enforced, U-shape zipper and 2 zipper pulls with tie ribs.
adult size 250x120cm
Protector Body Bag specifications:
• 300 microns
• 6 handles
• Impermeable, linear reinforced LLDPE, LDPE, EVA, PEVA, (avoid PVC), minimum thickness 400 microns;
• Should be able to hold 100-125 kilos (200-250 lbs),
Body bag • Should contain no chlorides: burning of chlorides pollute the environment and can cause damage to retort chambers. Body bags should be non
carcinogenic to health of funeral workers when used for cremations.
• At least 6 handles included in the body bag to allow burial team to hand carry it safely
• Heat-sealed: insure superior strength and safety,
• Provide full containment of blood borne pathogens
• Cracking point of 25 - 32 degrees below zero
• Shelf life: minimum 10 years
• Bag and hands should be white color
Aetiological
Treatment
Treatments (eg. Antivirals On outbreak-specific basis, consider: investigational therapeutics for consideration under Monitored Emergency Use of Unregistered and Investigational
and monoclonal antibodies) Interventions (MEURI)
Compound Sodium Lactate

Compound solution of sodium lactate (Ringer's lactate), injection solution, w/o IV set and needle, 1000ml
Supportive
Treatment
Solution
Infusion giving set Infusion giving set, with airinlet and needle, sterile, single-use
Paracetamol Paracetamol, 500mg, tablets

Gloves,
examination

examination gloves)
Made of clear plastic and provides good visibility to both the wearer and the
patient, Adjustable band to attach firmly around the head and fit snuggly against • EU standard directive 86/686/EEC, EN 166/2002,
Face shield the forehead, Fog resistant (preferable), Completely cover the sides and length • ANSI/ISEA Z87.1-2010,
of the face, May be re-usable (made of robust material which can be cleaned and or equivalent
disinfected) or disposable.

Sizes: M, L, XL
Face mask,
N95 or higher
EN 14683 Type IIR performance

ASTM F2100 level 2 or level 3
Medical/surgical mask, high fluid resistance, good breathability, internal and or equivalent;
Mask,
external faces should be clearly identified, structured design that does not • Fluid resistance at minimum 120 mmHg pressure based on ASTM
surgical
CASE MANAGEMENT
collapse against the mouth (e.g. duckbill, cup-shaped) F1862-07, ISO 22609, or equivalent
• Breathability: MIL–M-36945C, EN 14683 annex C, or equivalent
• Filtration efficiency: ASTM F2101, EN14683 annex B, or equivalent
PPE Health Care Facilities

• Option 1: fluid penetration resistant: EN 13795 high performance, or

Single use, fluid resistant, disposable, length mid-calf to cover the top of the AAMI PB70 level 3 performance or above, or equivalent
thumb/finger loops or elastic cuff to anchor sleeves in place. level 4 performance, or (EN 14126-B) and partial body protection ( EN
13034 or EN 14605), or equivalent
single use, fluid resistant, adjustable and should stay securely in place once adjusted, facial opening constructed without elastic, cover reaches upper
Head cover
part of the gown
disposable.
Apron, disposable or single use, made of polyester with PVC-coated, or other waterproof material, Straight apron with bib, minimum basis weight:
Apron 250g/m2, waterproof,
Covering size: 70-90 cm (width) X 120-150cm (height), or standard adult size
Alcohol-based hand rub bottle of 100ml
Bio-hazardous bag
• 6 handles
• Should contain no chlorides: burning of chlorides pollute the environment and can cause damage to retort chambers. Body bags should be non
Body bag
Sprayer, hand-held 1,5 liters, acid resistant

Logistics
Health
Sprayer, backpack 12 liters, acid resistant
Chlorine NaDCC, granules, 1kg, 65 to 70% + dossage spon

Marburg Virus Disease Disease Commodity Packages
Agent's Biosafety Level: BSL4 Marburg Virus Disease [LINK]

Epidemic Potential: Urban - high, Rural -medium Last Update: 21 September 2018 Managing Epidemics Handbook [LINK]
Samples collected from patients are an extreme biohazard risk; Polymerase Chain Reaction (PCR) Immunoassay
laboratory testing on non-inactivated samples should be
conducted under maximum biological containment conditions. All Blood & Nasopharyngeal samples One RT-PCR under WHO Emergency
biological specimens should be packaged using the triple 1 test under EUAL
Use Assessment and Listing (EUAL) & in-
packaging system when transported nationally and internationally. several in-house ELISA tests
house RT-PCR tests
Infection Protection & Control
PREVENTION & CONTROL Travel & Trade Vaccine Post-Exposure
(IPC)
Personal Protective Equipment (PPE)
On outbreak-specific basis, for screening (standard), in health On outbreak-specific basis, and as
Marburg transmits from person to person through close contact. Temperature screening at
consider: rVSV-MBGV / Ad26- care facilities & safe and dignified
Strict IPC measures with appropriate PPE are key to control airports/entry points of affected per most recent guidance in the
ZEBOV/MVA-BN®-Filo under burials
outbreaks. countries R&D Blueprint.
expanded access use.
PPE Guidelines [LINK]

Isolated patients must be placed in intensive care and receive Several candidates under consideration. On
IV Fluids critical PPE for Treatment in Healthcare Facilities (See
supportive treatment. Aetiological treatment available only under outbreak-specific basis, the Monitored Emergency
Intensive care for isolated patient PPE Guidelines Link)
EUAL. Use of Unregistered Interventions (MEURI) may be
Pain & Fever
considered

• Treatments (eg. Antiviral and monoclonal) under MEURI to reduce mortality
• Personal Protective Equipment and material for the establishment of IPC measures at health care level to reduce transmission
• Personal Protective Equipment and material for the execution of safe and dignified burials to reduce transmission

Guidance on regulations for Transport of
Infectious Substances 2017 - 2018
Sample Collection
Tubes, blood collection, Vacuum tube used for blood collection with EDTA, sterile, capped with vacuum seal. Material:
EDTA plastic. 4 ml and 6 ml
SURVEILLANCE
Tubes, blood collection, Vacuum tube used for plain/dry blood collection without anticoagulant, sterile, capped with
plain/dry vacuum seal. Material: plastic. 4 ml and 6 ml
Puncture resistant container for collection and disposing of used, disposable and auto-disable
Sharps container boxes syringes, needles. 5 L capacity accommodating approximately 100 syringes. Boxes
prominently marked.
Vaccine Temperature Screening Diagnostics
Criteria for selection of specific diagnostic tests may include historical efficacy, adherence to any existing Target Product Profiles, ease of use, necessary throughput, distribution and
logistics requirements, and manufacturer production capacity. For some pathogens, consideration may need to be given to the presence of mutations in targeted gene sequences or
proteins. WHO can advise on the selection of tests on a case by case basis as determined by a specific event.
• ISO 80601-2-56:2009
• ISO 80601-2-59 Ed. 1.0:2008
• ASTM E1104-98(2003)
Handheld battery-powered electronic instrument designed to estimate body temperature od a • ASTM E1965-98(2009)
Thermometer, Infrared site on skin (e.g. forehead) non-invasively, quickly without touching. A sensor can be cleaned • ASTM E1112-00(2011)
easily by each use with wiping by disinfectant or sterilisable cover. • JIS T 4207:2005
• or equivalent
WHO Core - Thermometers, electronic,
[LINK]
infrared
Under Expanded Access use. None approved to date. (Please see R&D Blueprint link above.)
OSL | Disease Commodity Packages 5 MARBURG VIRUS DISEASE

Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach mid-forearm
(eg. minimum 280mm total length. Sizes, S, M, L
Gloves,
• ANSI/ISEA 105-2011,
examination Outer glove should have long cuffs, reaching well above the wrist, ideally to mid-forearm.
• ASTM D6319-10
Inner glove should be worn under the cuff of the gown/coveralls (and under any thumb/finger
• or equivalent
loop) whereas the outer glove should be worn over the cuff of the gown/coveralls.

Outer glove should have long cuffs, reaching well above the wrist, ideally to mid-forearm. • ANSI/ISEA 105-2011,
Inner glove should be worn under the cuff of the gown/coveralls (and under any thumb/finger • ASTM 6319-10
examination gloves)
PPE - Standard
loop) whereas the outer glove should be worn over the cuff of the gown/coveralls. Sizes 5 to • or equivalent
8.5
"Surgical N95 respirator" cleared by the US FDA and

Fluid resistant particulate respirator. Surgical N95 respirator or higher
Face mask, NIOSH, or equivalent
High fluid resistance, Good breathability, Internal and external faces should be clearly
particulate respirator, grade • Fluid resistant surgical N95 respirator with minimum 80
identified, Structured design that does not collapse against the mouth (e.g. duckbill, cup-
N95 or higher mm Hg pressure based on ASTM F1862, ISO 22609 , or
shaped)
equivalent
• Option 1: fluid penetration resistant: EN 13795 high

performance, or AAMI PB70 level 3 performance or above,
Single use, fluid resistant, disposable, length mid-calf to cover the top of the boots, light or equivalent
Gown colours preferable to better detect possible contamination, thumb/finger loops or elastic cuff to • Option 2: blood borne pathogens penetration resistant:
anchor sleeves in place. AAMI PB70 level 4 performance, or (EN 14126-B) and
partial body protection ( EN 13034 or EN 14605), or
equivalent

• EN 374 (AS/NZS 2161.10.1.2005) chemical resistance
for AKL
Gloves, Covering forearm. Fabric: cotton or polyester, rubber coating, waterproof, and acid resistant,
performance, or above
heavy duty minimum cuff length 150mm
• EN 388 (AS/NZS 2161.10.3.2005) 3111 for abrasion,
blade cut, tear and puncture, or above
• EN 420:2004+A1:2009

shaped)
equivalent
Good seal with the skin of the face, Flexible PVC frame to easily fit with all face contours with
even pressure, Enclose eyes and the surrounding areas, Accomodate wearers with • EU standard directive 86/686/EEC, EN 166/2002,
Goggles, prescription glasses, Clear plastic lens with fog and scratch resistant treatments, Adjustable • ANSI/ISEA Z87.1-2010,
protective band to secure firmly so as not to become loose during clinical activity, Indirect venting to or equivalent
avoid fogging, May be re-usable (provided appropriate arrangements for decontamination are
in place) or disposable.
• Option 1: blood and body fluid penetration resistant:

meets or exceeds ISO 16603 class 3 or above exposure
Single use, light colours preferable to better detect possible contamination, thumb/finger loops pressure, or equivalent
Coverall
to anchor sleeves in place, good freedom of movement. Sizes: M, L, XL • Option 2: blood-borne pathogens penetration
resistant:meets or exceeds ISO 16604 class 2 or above
exposure pressure, or equivalent
Burial Teams
Scrubs,
Tunic/tops, woven, scrubs, reusable or single use, short sleeved (tunic/tops), worn underneath the coveralls or gown.
tops
Scrubs,
Trouser/pants, woven, scrubs, reusable or single use, short sleeved (tunic/tops), worn underneath the coveralls or gown
pants

May comply with
Fabric: 100% polyester with PVC coating, or 100% PVC, or 100% rubber, or other fluid
• EN ISO 13688:2013
Apron, resistant material, Waterproof, Sewn strap for neck and back fastening
• EN 14126-B and partial body protection (EN 13034 or EN
heavy duty, reusable Minimum basis weight: 300g/m2
14605)
covering size: 70-90 cm (width) X 120-150cm (height)
or equivalent
Bio-hazardous bag

• 6 handles
Body bag
Aetiological
Treatment
Treatments (eg. Antivirals Several candidates under consideration. On outbreak-specific basis, the Monitored Emergency Use of Unregistered Interventions (MEURI) may be
and monoclonal antibodies) considered

Supportive
Treatment
Solution
Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach mid-forearm
(eg. minimum 280mm total length. Sizes, S, M, L
Gloves,
• ANSI/ISEA 105-2011,
examination Outer glove should have long cuffs, reaching well above the wrist, ideally to mid-forearm.
• ASTM D6319-10
Inner glove should be worn under the cuff of the gown/coveralls (and under any thumb/finger
• or equivalent
loop) whereas the outer glove should be worn over the cuff of the gown/coveralls.

examination gloves)
8.5
Made of clear plastic and provides good visibility to both the wearer and the patient,
Adjustable band to attach firmly around the head and fit snuggly against the forehead, Fog
Face shield • ANSI/ISEA Z87.1-2010,
resistant (preferable), Completely cover the sides and length of the face, May be re-usable
or equivalent
(made of robust material which can be cleaned and disinfected) or disposable.

Single use, light colours preferable to better detect possible contamination, thumb/finger loops pressure, or equivalent
Coverall
to anchor sleeves in place, good freedom of movement. Sizes: M, L, XL • Option 2: blood-borne pathogens penetration

shaped)
equivalent

or equivalent;
Medical/surgical mask, high fluid resistance, good breathability, internal and external faces • Fluid resistance at minimum 120 mmHg pressure based
Mask,
should be clearly identified, structured design that does not collapse against the mouth (e.g. on ASTM F1862-07, ISO 22609, or equivalent
CASE MANAGEMENT
surgical
duckbill, cup-shaped) • Breathability: MIL–M-36945C, EN 14683 annex C, or
equivalent
• Filtration efficiency: ASTM F2101, EN14683 annex B, or

equivalent


Single use, fluid resistant, disposable, length mid-calf to cover the top of the boots, light or equivalent
Gown colours preferable to better detect possible contamination, thumb/finger loops or elastic cuff to • Option 2: blood borne pathogens penetration resistant:
anchor sleeves in place. AAMI PB70 level 4 performance, or (EN 14126-B) and
equivalent
single use, fluid resistant, adjustable and should stay securely in place once adjusted, facial opening constructed without elastic, cover reaches upper part
Head cover of the gown
Good seal with the skin of the face, Flexible PVC frame to easily fit with all face contours with
even pressure, Enclose eyes and the surrounding areas, Accomodate wearers with • EU standard directive 86/686/EEC, EN 166/2002,
avoid fogging, May be re-usable (provided appropriate arrangements for decontamination are
in place) or disposable.
Alcohol-based hand rub Bottle of 100ml
Bio-hazardous bag
• 6 handles
Body bag

Logistics
Health

Lassa Fever Disease Commodity Packages
Agent's Biosafety Level: BSL4 Lassa Fever [LINK]

Epidemic Potential: Medium Last Update: 21 September 2018 Managing Epidemics Handbook [LINK]
Polymerase Chain Reaction (PCR) Immunoassay

Definitive diagnosis requires testing that is available only in
reference laboratories. Laboratory specimens may be Blood & Nasopharyngeal samples 1 RT-PCR Non-prequalified (NPQ)
hazardous and must be handled with extreme care. with 2 targets (GPC gene and L Several in-house IgM/IgG ELISAs
gene)
PREVENTION & CONTROL Vector Control Infection Protection & Control (IPC) Post Exposure Propyylaxsis
Oral Ribavirin.
Humans get primarily infected through exposure to rats' urine Personal Protective Equipment (PPE) for screening
On outbreak-specific basis, and as per
or faeces. Human to human transmssion occurs through direct (standard) in health facilities & for teams conducting safe and
most recent guidance in the R&D
contact with bodily fluids of infected persons, therefore strict Rodents dignified burials
Blueprint.
IPC measures with appropriate PPE are key to control
outbreaks.
Therapeutic Workshop
PPE Guidelines [LINK] [LINK]
Document

Ribavirin IV, Lassa Treatment in pipeline
Isolated patients must be placed in intensive care and receive (Oral presentation, IV presentation in IV Fluids critical
PPE for Treatment in Healthcare Facilities
aetiological & supportive treatment. production), Intensive care for isolated patient
Pain & Fever
Therapeutic Workshop
[LINK]
Document

• Antiviral treatment to reduce mortality
• Personal Protective Equipment and material for the execution of safe and dignified burials to reduce transmission

Sample Collection
Tubes, blood collection, Vacuum tube used for blood collection with EDTA, sterile, capped with vacuum
EDTA seal. Material: plastic. 4 ml and 6 ml
SURVEILLANCE
Tubes, blood collection, Vacuum tube used for plain/dry blood collection without anticoagulant, sterile,
plain/dry capped with vacuum seal. Material: plastic. 4 ml and 6 ml
Puncture resistant container for collection and disposing of used, disposable

Sharps container boxes and auto-disable syringes, needles. 5 L capacity accommodating
approximately 100 syringes. Boxes prominently marked.
Temperature Screening Diagnostics
Criteria for selection of specific diagnostic tests may include historical efficacy, adherence to any existing Target Product Profiles, ease of use, necessary throughput, distribution
and logistics requirements, and manufacturer production capacity. For some pathogens, consideration may need to be given to the presence of mutations in targeted gene
sequences or proteins. WHO can advise on the selection of tests on a case by case basis as determined by a specific event.
• ISO 80601-2-56:2009
• ISO 80601-2-59 Ed. 1.0:2008
• ASTM E1104-98(2003)
Handheld battery-powered electronic instrument designed to estimate body • ASTM E1965-98(2009)
temperature od a site on skin (e.g. forehead) non-invasively, quickly without • ASTM E1112-00(2011)
Thermometer, Infrared
touching. A sensor can be cleaned easily by each use with wiping by • JIS T 4207:2005
disinfectant or sterilisable cover. • or equivalent
OSL | Disease Commodity Packages 9 LASSA FEVER


Gloves,
Outer glove should have long cuffs, reaching well above the wrist, ideally to • ANSI/ISEA 105-2011,
examination
mid-forearm. Inner glove should be worn under the cuff of the gown/coveralls • ASTM D6319-10
(and under any thumb/finger loop) whereas the outer glove should be worn • or equivalent
over the cuff of the gown/coveralls.

PPE - Standard
mid-forearm. Inner glove should be worn under the cuff of the gown/coveralls • ASTM 6319-10
examination gloves)
over the cuff of the gown/coveralls. Sizes 5 to 8.5
Face mask,
particulate respirator,
grade N95 or higher
• Option 1: fluid penetration resistant: EN 13795 high performance,

Single use, fluid resistant, disposable, length mid-calf to cover the top of the or AAMI PB70 level 3 performance or above, or equivalent
thumb/finger loops or elastic cuff to anchor sleeves in place. level 4 performance, or (EN 14126-B) and partial body protection (
EN 13034 or EN 14605), or equivalent

• EN 374 (AS/NZS 2161.10.1.2005) chemical resistance for AKL
Gloves, Covering forearm. Fabric: cotton or polyester, rubber coating, waterproof, and performance, or above
heavy duty acid resistant, minimum cuff length 150mm • EN 388 (AS/NZS 2161.10.3.2005) 3111 for abrasion, blade cut,
tear and puncture, or above
• EN 420:2004+A1:2009
Face mask,
grade N95 or higher
become loose during clinical activity, Indirect venting to avoid fogging, May be
re-usable (provided appropriate arrangements for decontamination are in
place) or disposable.

exceeds ISO 16603 class 3 or above exposure pressure, or
equivalent
Sizes: M, L, XL
equivalent
Burial Teams

Fabric: 100% polyester with PVC coating, or 100% PVC, or 100% rubber, or
other fluid resistant material, Waterproof, Sewn strap for neck and back May comply with
Apron, fastening • EN ISO 13688:2013
heavy duty, non-woven Minimum basis weight: 300g/m2 • EN 14126-B and partial body protection (EN 13034 or EN 14605)
covering size: 70-90 cm (width) X 120-150cm (height) or equivalent
Reusable (provided appropriate arrangements for decontamination are in
place)
Bio-hazardous bag

• 6 handles
Body bag
Aetiological
Treatment
Ribavirin Ribavirin IV, 1000mg dissolved in 10ml phosphate buffer solution, vial.
Compound Sodium
Lactate Solution
Supportive
Treatment

Gloves,
examination
mid-forearm. Inner glove should be worn under the cuff of the gown/coveralls • ASTM D6319-10
over the cuff of the gown/coveralls.

mid-forearm. Inner glove should be worn under the cuff of the gown/coveralls • ASTM 6319-10
examination gloves)
over the cuff of the gown/coveralls. Sizes 5 to 8.5
patient, Adjustable band to attach firmly around the head and fit snuggly • EU standard directive 86/686/EEC, EN 166/2002,
Face shield against the forehead, Fog resistant (preferable), Completely cover the sides • ANSI/ISEA Z87.1-2010,
and length of the face, May be re-usable (made of robust material which can be or equivalent
cleaned and disinfected) or disposable.

equivalent
Sizes: M, L, XL
equivalent
Face mask,
grade N95 or higher

CASE MANAGEMENT
Medical/surgical mask, high fluid resistance, good breathability, internal and or equivalent;
Mask,
external faces should be clearly identified, structured design that does not • Fluid resistance at minimum 120 mmHg pressure based on ASTM
surgical
collapse against the mouth (e.g. duckbill, cup-shaped) F1862-07, ISO 22609, or equivalent
• Breathability: MIL–M-36945C, EN 14683 annex C, or equivalent

• Filtration efficiency: ASTM F2101, EN14683 annex B, or equivalent

• Option 1: fluid penetration resistant: EN 13795 high performance,

Single use, fluid resistant, disposable, length mid-calf to cover the top of the or AAMI PB70 level 3 performance or above, or equivalent
thumb/finger loops or elastic cuff to anchor sleeves in place. level 4 performance, or (EN 14126-B) and partial body protection (
EN 13034 or EN 14605), or equivalent
single use, fluid resistant, adjustable and should stay securely in place once adjusted, facial opening constructed without elastic, cover reaches upper
Head cover
part of the gown
become loose during clinical activity, Indirect venting to avoid fogging, May be
re-usable (provided appropriate arrangements for decontamination are in
place) or disposable.
Bio-hazardous bag
• 6 handles
Body bag
Logistics
Health

Cholera Disease Commodity Packages
Agent's Biosafety Level: BSL2 Cholera [LINK]

Epidemic Potential: High Last Update: 21 September 2018 Managing Epidemics Handbook [LINK]
Polymerase Chain
Rapid Diagnostic Test (RDT) Culture
The usual approach for patient diagnosis and surveillance of Reaction (PCR)
cholera is based on clinical examination of suspected cholera
cases, with confirmation by positive culture of stool specimens in Stool or rectal swab
Several tests Several RT-PCR Antiserum and
reference laboratories. Culture is very specific and is considered the
Non-prequalified (NPQ) Non-prequalified (NPQ) AMS required
reference-standard method in most countries.
PREVENTION & CONTROL Vaccine WASH Safe and dignified burial
Provision of safe water, proper sanitation, and food safety are

critical for preventing the occurrence and spread of cholera. Mass Oral Cholera Vaccines (OCV)
Personal Protective Equipment (PPE) +
chemoprophylaxis is not recommended because it has no available through the ICG Safety of water sources (chlorination, flitration,
Disinfection supplies (for Infection Protection
demonstrated effect on the spread of cholera, can have adverse mechanism or direct procurement etc.); household water treatment
& Control)
effects by increasing antimicrobial resistance and provides a false to manufacturers
sense of security.
CASE MANAGEMENT Treatment Isolation of patients

Aetiological Supportive Treatment Units & Centres
Proper case management calls for prompt rehydration via oral
rehydration salts (ORS) or IV fluids , depending on the severity of Oral Rehydration Salts (ORS), IV
cases. Up to 80% of patients can be treated effectively with ORS. Doxycycline + Zinc for pediatrics Fluids critical, Pain & Fever, cholera See Revised Cholera Kit [LINK]
Severe cases need to receive antibiotic treatment. beds
• Aetiological treatment to reduce mortality

• Supportive treatment (hydration) to reduce mortality
• Provision of safe water to reduce transmission

Collection
Swabs CultureSwab, Cary-Blair Agar, single swab

Sample
Faeces collection container 125ml with screw cup

SURVEILLANCE
Diagnostics
Culture
Please see "Manual for the laboratory identification and antimicrobial susceptibility testing of bacterial pathogens of public health importance in
[LINK]
the developing world"
Euvichol Inactivated oral cholera vaccine, 1 dose vial

Vaccine
Dukoral Inactivated oral cholera vaccine, cholera toxin B subunit (recombinat), 1 dose vial + buffer sachet
Shanchol/mORCVAX Inactivated oral cholera vaccine, 1 dose vial
• Kit water tank, 5 m3, flexible 1 acc.2" DIN50

• Water distribution module, 2 ramps x 6 taps
• Hoses module, 2'' DIN 50 + coupling
WASH
• Tester, pool tester

Safe Water Module
• Chlorine test tablets DPD1
• Phenol red tablets for cholrine testing
• NaDCC, granules, 1kg, 65 to 70% + dossage spoon (contingent upon necessary concentration levels)
Chlorine NaDCC, granules, 1kg, 65 to 70% + dossage spoon

IPC
Bar soap
OSL | Disease Commodity Packages 13 CHOLERA

Cholera Disease Commodity Packages

• EN 374 (AS/NZS 2161.10.1.2005) chemical resistance
for AKL
• EN 374 (AS/NZS 2161.10.1.2005) for biohazards Level
Gloves, Covering forearm. Fabric: cotton or polyester, rubber coating, waterproof, and acid
3 performance, or above
heavy duty resistant, minimum cuff length 150mm
• EN 388 (AS/NZS 2161.10.3.2005) 3111 for abrasion,
blade cut, tear and puncture, or above
• EN 420:2004+A1:2009

shaped)
equivalent
contours with even pressure, Enclose eyes and the surrounding areas, Accomodate • EU standard directive 86/686/EEC, EN 166/2002,
Goggles, wearers with prescription glasses, Clear plastic lens with fog and scratch resistant • ANSI/ISEA Z87.1-2010,
protective treatments, Adjustable band to secure firmly so as not to become loose during clinical or equivalent
activity, Indirect venting to avoid fogging, May be re-usable (provided appropriate
arrangements for decontamination are in place) or disposable.

Single use, light colours preferable to better detect possible contamination, thumb/finger pressure, or equivalent
Coverall
loops to anchor sleeves in place, good freedom of movement. Sizes: M, L, XL • Option 2: blood-borne pathogens penetration
Burial Teams

May comply with
Fabric: 100% polyester with PVC coating, or 100% PVC, or 100% rubber, or other fluid
• EN ISO 13688:2013
Apron, resistant material, Waterproof, Sewn strap for neck and back fastening
• EN 14126-B and partial body protection (EN 13034 or
heavy duty, non-woven Minimum basis weight: 300g/m2
EN 14605)
covering size: 70-90 cm (width) X 120-150cm (height)
or equivalent
Non-slip sole pattern, PVC or polyurethane sole which is completely sealed and waterproof, Knee-high in order be higher than the bottom edge of
Boot, rubber the gown, Range of sizes available to improve comfort and avoid trauma to the feet, Materials of construction include rubber, PVC, neoprene,
nitrile, polyurethane, Favor light colours to better identify possible contaminations.
Bio-hazardous bag
• 6 handles
Body bag
Aetiological
Treatment
Doxycycline Doxycycline, single dose, 100mg tablets
Zinc sulfate Zinc sulfate, 20mg, dispersible tablets

Solution
CASE MANAGEMENT
ORS ORS (oral rehydration salts), low osmolarity 20.5g, sachet for 1 litre
reatment

CASE MANAGEMENT

Cholera
Supportive Treatment
Disease Commodity Packages
• Cot weight: 31 lbs (14 kgs)

• Weight tolerance: 350 lbs (159 kgs)
• Outer dimensions: 82" (208 cm) L x 43.5" (82.5 cm) W x 20.5" (52 cm) H
• Sleep area: 79" (201 cm) L x 28 " (70 cm) W
• Height of cot: 16" (41 cm)
Cholera beds • Bag dimensions: 32" (81.5 cm) L x 20" (42 cm) W x 4" (11 cm) H
• Silver, powder coated, anti-rust steel frame
• White, double-sided 18oz vinyl coated polyester, with wielded hole
• CPSIA compliant
• Mat features 8" (20cm) diameter cut out hole with impermeable welded seam
• Mat is impermeable with ultrasonically welded construction, no threads or sew lines

Influenza (Pandemic) Disease Commodity Packages
Agent's Biosafety Level: BSL2 Influenza (Pandemic) [LINK]

Epidemic Potential: High Last Updated: 21 September 2018 Managing Epidemics Handbook [LINK]
Rapid Diagnostic
Blood & nasophyrangeal samples Polymerase Chain Reaction (PCR) Culture
Test (RDT)
The primary aims of surveillance are threefold: to monitor Test for influenza
changes in antigenicity of influenza viruses; to guide the A&B and H1&H3,
selection of strains for the annual influenza vaccine; and to RT-PCR Diagnostic panels, A/B
A/H7N9 Viral transport
provide virus samples for use in vaccine production. typing kits
Collecting, Preserving and Shipping for Diagnosis of Avian Emergency Use medium
40+ Nucleic Acid Based Test
Influenza Assessment and
[LINK] Listing (EUAL)
PREVENTION & CONTROL Chemoprophylaxsis Vaccine Infection Protection & Control (IPC)
Switch to pandemic vaccine
Vaccination is the primary intervention to prevent infection
production will be decided by Personal Protective Equipment (PPE) in health care
and severe outcomes caused by influenza virus. However,
technical advisory group. facilities in outbreak affected areas
at the beginning of a pandemic, Pandemic influenza
Vaccine supply will be made
vaccines, matching the new virus, will most likely not be
available under the PIP
available. PPE Guidelines [LINK]
framework.
PIP Framework [LINK]
Pulse oximeter to assess patients at all health care levels
PPE for health care facilities.
essential. Oxygen Therapy for patients with complicated According to sensitivity
Respiratory (standard, droplet IPC); airborne
influenza disease and mechanical ventilation for patients (Oseltamivir,
Oxygen Therapy for severe case (~10%), use of precautions for aerosolyzed generating
with most severe disease. Ventilation to be provided in Zanamivir). Included on WHO EML
Oximeter highly recommended. Intensive care critical procedures.
intensive care units with trained staff and protocols, when for severe illness due to confirmed or
for severe cases, hydration, fever/pain (Please see PPE Guidelines)
available. suspected influenza virus infection in
critically ill hospitalized patients.
• RDT to improve disease indentification

• Aetiological Treatment to reduce severity and mortality
• Supportive treatment (oxygen, hydration & fever/pain relief) to reduce mortality

Viral Transport Medium Medium for specimen to transport to laboratory

Sample Collection
Tubes, blood collection, Vacuum tube used for blood collection with EDTA, sterile, capped with vacuum seal.
EDTA Material: plastic. 4 ml and 6 ml
SURVEILLANCE
Tubes, blood collection, Vacuum tube used for serum collection, sterile, capped with vacuum seal. Material: plastic.
serum 4 ml and 6 ml
Tubes, blood collection, Vacuum tube used for plain/dry blood collection without anticoagulant, sterile, capped with
plain/dry vacuum seal. Material: plastic. 4 ml and 6 ml
Puncture resistant container for collection and disposing of used, disposable and auto-
Sharps container boxes disable syringes, needles. 5 L capacity accommodating approximately 100 syringes. Boxes
prominently marked.
Diagnostics
Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach mid- • EU standard directive 93/42/EEC Class I, EN 455,
forearm (eg. minimum 280mm total length. Sizes, S, M, L • EU standard directive 89/686/EEC Category III, EN
Gloves, 374,
examination Outer glove should have long cuffs, reaching well above the wrist, ideally to mid-forearm. • ANSI/ISEA 105-2011,
Inner glove should be worn under the cuff of the gown/coveralls (and under any thumb/finger • ASTM D6319-10
loop) whereas the outer glove should be worn over the cuff of the gown/coveralls. • or equivalent
OSL | Disease Commodity Packages 16 INFLUENZA


Gloves, surgical, length
to forearm large (longer
than examination gloves)
8.5
resistant (preferable), Completely cover the sides and length of the face, May be re-usable
or equivalent
(made of robust material which can be cleaned and disinfected) or disposable.
Fit Test Kit To evaluate effectiveness of seal for tight fitting respiratory protection devices OSHA 29 CFR 1910.134 Appendix A

Single use, light colours preferable to better detect possible contamination, thumb/finger pressure, or equivalent
Coverall
loops to anchor sleeves in place, good freedom of movement. Sizes: M, L, XL • Option 2: blood-borne pathogens penetration

particulate respirator, • Fluid resistant surgical N95 respirator with minimum 80
grade N95 or higher mm Hg pressure based on ASTM F1862, ISO 22609 , or
shaped)
equivalent

or equivalent;
Mask,
should be clearly identified, structured design that does not collapse against the mouth (e.g. on ASTM F1862-07, ISO 22609, or equivalent
surgical
duckbill, cup-shaped) • Breathability: MIL–M-36945C, EN 14683 annex C, or
equivalent
IPC - PPE Health Care Facilities
• Filtration efficiency: ASTM F2101, EN14683 annex B,

or equivalent
Prevention & Control

performance, or AAMI PB70 level 3 performance or
Single use, fluid resistant, disposable, length mid-calf to cover the top of the boots, light above, or equivalent
Gown colours preferable to better detect possible contamination, thumb/finger loops or elastic cuff • Option 2: blood borne pathogens penetration resistant:
to anchor sleeves in place. AAMI PB70 level 4 performance, or (EN 14126-B) and
equivalent
Single use, fluid resistant, adjustable and should stay securely in place once adjusted, facial opening constructed without elastic, cover reaches upper
Head cover
part of the gown
Good seal with the skin of the face, Flexible PVC frame to easily fit with all face contours
with even pressure, Enclose eyes and the surrounding areas, Accomodate wearers with • EU standard directive 86/686/EEC, EN 166/2002,
avoid fogging, May be re-usable (provided appropriate arrangements for decontamination
are in place) or disposable.
Bio-hazardous bag

• 6 handles
Body bag

Aetiological
Treatment
Oseltamivir Oseltamivir, capsule, 75mg in pack of 10
Zanamivir
Compound Sodium
Lactate Solution
WHO Core:
Device concentrates oxygen from ambient air. On 4 antistatic swivel castors, 2 with brakes. Integrated handle allows Concentrator, [LINK]
for easy moving and positioning. Oxygen sensing device is integrated and measures concentration at flow meter Oxygen
entrance. Four-step filtering of air-intake, including bacterial filter. All filters replaceable, coarse filter
Oxygen concentrators
washable/reusable. Continuous monitoring with visual and audible alerts, on low 'high output pressure, low oxygen Oxygen
concentration, power failure and battery test. Operating conditions: Temperature between 5 to 45 degrees Celsius, Concentrator [LINK]
Relative humidity max. 90% without condensation. Spare parts should be required for operating at least one year. Technical Guidelines
(Oxygen concentrator) Splitter of oxygen flow provided by an oxygen concentrator. Each flow can be adjusted individually via its flow meter, range: 0.125 to 2LPM (Liter Per
Flow splitter Minute). The output nozzle can either be fit with tubing or left blank. Input pressure: 50 to 350kPa.
Nasal prongs (nasal cannula) is a device designed for easy administration of oxygen and comfort of patient. The device consists of a plastic tube which
Oxygen prongs, nasal, fits behind the ears, and a set of two prongs which are placed in the nostrils. Soft twin prongs nasal tips to ensure equal oxygen flow to both.Star lumen
non-sterile, single use main tube to avoid accidental blockage. Adjustable, smoothly finished, nasal tips for maximum patient comfort. Soft funnel shaped connector to
facilitate easy connection to oxygen source. Oxygen tube length: approximately 2m.
Tube used to deliver oxygen through the nose. Material: PVC. Automatic, open distal (patient) end, with 6 to 12 lateral eyes. Proximal end with
Oxygen tube, extension connector enabling the tube to be connected to an oxygen supply tube of any diameter (e.g. serrated male conical tip). Sterile, for single patient use.
Diameter: CH 10. Length: 40cm
a) Tidal volume up to 1,000 mL.

b) Pressure (inspiratory) up to 80 cm H20
c) Volume (inspiratory) up to 120 L/min
d) Respiratory rate: up to 60 breaths per minute.
e) SIMV Respiratory Rate: up to 40 breaths per minute. • ISO 13485:2003 Medical devices -- Quality
f) CPAP/PEEP up to 20 cm H2O. management systems -- Requirements for regulatory
g) Pressure support up to 45 cm H2O. purposes (Australia, Canada and EU)
h) FiO2 between 21 to 100 % • ISO 14971:2007 Medical devices -- Application of risk
i) Inspiratory and expiratory times up to at least 2 sec and 8 sec respectively management to medical devices IEC 60601-1:2012
CASE MANAGEMENT
j) I:E Ratio at least from 1:1 to 1:3. Medical electrical equipment - Part 1: General
2 Modes of ventilation: requirements for basic safety and essential performance
a) Volume controlled. • IEC 60601-1-1:2000 Medical electrical equipment - Part
b) Pressure controlled. 1-1: General requirements for safety - Collateral
Portable ventilator
c) Pressure support. standard: Safety requirements for medical electrical
d) Synchronized intermittent mandatory ventilation (SIMV) with pressure support. systems
e) Assist / control mode • IEC 60601-1-2:2007 Medical electrical equipment - Part
f) CPAP/PEEP 1-2: General requirements for basic safety and essential
Alarms required: FiO2, minute volume, pressure, PEEP, apnoea, occlusion, high respiration performance - Collateral standard: Electromagnetic
rate, disconnection compatibility - Requirements and tests
System alarms required: power failure, gas disconnection, low battery, vent inoperative, self • ISO 80601-2-12:2011 Medical electrical equipment --
diagnostics Part 2-12: Particular requirements for basic safety and
If alarm silencing feature is incorporated, it must be temporary and clearly displayed when essential performance of critical care ventilators
activated
Air and externally supplied oxygen mixture ratios fully controllable
Inlet gas supply (O2) pressure range at least 35 to 65 psi
Medical air compressor integral to unit, with inlet filter

Compact portable device measures arterial blood oxygen saturation (SpO2), heart rate and
signal strength. Measuring range: SpO2 30 to 100% (minimum graduation 1%), Heart rate
Pulse Oximeter ISO 80601-2-61:2011or equivalent
20 to 250 bpm (minimum graduation 1bpm). Line-powered, or Extra-batteries/rechargeable
batteries are required at least one year.
Water for injection Water for injection, 10ml ampule
Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach mid- • EU standard directive 93/42/EEC Class I, EN 455,
Gloves, forearm (eg. minimum 280mm total length. Sizes, S, M, L • EU standard directive 89/686/EEC Category III, EN
examination 374,

Gloves, surgical, length
to forearm large (longer
than examination gloves)
8.5
PPE - Standard

shaped)
equivalent

Gown colours preferable to better detect possible contamination, thumb/finger loops or elastic cuff • Option 2: blood borne pathogens penetration resistant:
to anchor sleeves in place. AAMI PB70 level 4 performance, or (EN 14126-B) and
equivalent

MERS-CoV Disease Commodity Packages
Agent's Biosafety Level: BSL2, Virus culture BSL3 MERS-CoV [LINK]

Epidemic Potential: High Last Update: 21 September 2018 Managing Epidemics Handbook [LINK]
Laboratory confirmation of a MERS-CoV case will trigger an Polymerase Chain Reaction (PCR) Immunoassay Culture
immediate and thorough investigation. Because shipment
and testing of specimens can take several days or longer, Upper and lower respiratory samples (nasophyrangeal several commercial rRT-PCR kits 1 IgM/IgG ELISA (NPQ)
WHO's recommended strategy is to begin an investigation and sputum samples), blood available 2IgM/IgG IFAs (NPQ) Viral transport
immediately, thus requiring immediate operational support and 2 RT-PCR Confirmation via medium
supplies. Non-prequalified (NPQ) microneutralization
Laboraroty Testing for Middle East Respiratory Syndrome Coronvavirus - Interim Guidance January 2018 [LINK]
PREVENTION & CONTROL Travel & Trade Vaccine Infection Protection & Control (IPC)
Respiratory (standard, droplet IPC); Airborne precautions
MERS-CoV causes zoonotic infections in humans by direct or for aerosolyzed generating procedures, Personal
indirect contact with infected dromedary camels or camel- Protective Equipment (PPE) for screening
related products, but such primary infections account for a Several candidates in Use of PPE for at-risk health facilities
minority of cases. Most are infected from human-to-human development. Please refer to most
Restriction/ban of movement of camels
contact due to breaches in IPC practices. Thus, the central recent guidance established in the
focus of any prevention/control strategy is protecting R&D Blueprint.
healthcare workers with appropriate IPC supplies and PPE Guidelines
ensuring basic health logistics at responding facilities. [LINK]
Please see WHO MERS guidance [LINK]


Several candidates under PPE for at-risk health facilities
There is no proven specific treatment or vaccine, however Oxygen Therapy
consideration for evaluation. Respiratory (standard, droplet IPC); Airborn
there are ongoing R&D efforts. See WHO current guidance Mechanical Ventilation of severe
On outbreak-specific basis, the precautions for aerosolyzed generating
on case management for MERS. Rapid progression of the cases (40%)
Monitored Emergency Use of Antibiotics, procedures,
disease from severe pneumonia to respiratory failure usually Use of Oximeter highly
Unregistered Interventions Pain/Fever Possibly Home Care Kits for home isolation
occurs within the first week requiring rapid deployment and recommended
(MEURI) may be considered. of asymptomatic cases or mildly
use of supplies and health logistics support. Intubation, ICU, ECMO requried for
Please refer to most recent symptomatic (in the case of a large outbreak)
severe patients
WHO guidance.
• Supportive treatment (oxygen, antibiotics, hydration & fever/pain relief) to reduce mortality

Sample Collection

SURVEILLANCE
Puncture resistant container for collection and disposing of used, disposable and auto-
Sharps container boxes disable syringes, needles. 5 L capacity accommodating approximately 100 syringes.
Boxes prominently marked.
Sputum Collection Sputum collection container, 30ml, 5.7x3.5cm, with screw cap, autoclavable, polypropylene.
Diagnostics

Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach mid-
Gloves, forearm (eg. minimum 280mm total length. Sizes, S, M, L
• ANSI/ISEA 105-2011,
examination
• ASTM D6319-10
Gloves should have long cuffs, reaching well above the wrist, ideally to mid-forearm.
• or equivalent
OSL | Disease Commodity Packages 20 MERS-CoV


or equivalent;
Prevention & Control
PPE - Standard
Mask,
should be clearly identified, structured design that does not collapse against the mouth on ASTM F1862-07, ISO 22609, or equivalent
surgical
(e.g. duckbill, cup-shaped) • Breathability: MIL–M-36945C, EN 14683 annex C, or
equivalent
equivalent

Gown colours preferable to better detect possible contamination, thumb/finger loops or elastic • Option 2: blood borne pathogens penetration resistant:
cuff to anchor sleeves in place. AAMI PB70 level 4 performance, or (EN 14126-B) and
equivalent
WHO Core:
Device concentrates oxygen from ambient air. On 4 antistatic swivel castors, 2 with brakes. Integrated handle allows
Concentrator, [LINK]
for easy moving and positioning. Oxygen sensing device is integrated and measures concentration at flow meter
Oxygen
entrance. Four-step filtering of air-intake, including bacterial filter. All filters replaceable, coarse filter
Oxygen concentrators
washable/reusable. Continuous monitoring with visual and audible alerts, on low 'high output pressure, low oxygen
concentration, power failure and battery test. Operating conditions: Temperature between 5 to 45 degrees Celsius,
Relative humidity max. 90% without condensation. Spare parts should be required for operating at least one year. Oxygen Concentrator
[LINK]
Technical Guidelines
(Oxygen concentrator) Splitter of oxygen flow provided by an oxygen concentrator. Each flow can be adjusted individually via its flow meter, range: 0.125 to 2LPM (Liter Per
Flow splitter Minute). The output nozzle can either be fit with tubing or left blank. Input pressure: 50 to 350kPa.
Nasal prongs (nasal cannula) is a device designed for easy administration of oxygen and comfort of patient. The device consists of a plastic tube
Oxygen prongs, nasal, which fits behind the ears, and a set of two prongs which are placed in the nostrils. Soft twin prongs nasal tips to ensure equal oxygen flow to
non-sterile, single use both.Star lumen main tube to avoid accidental blockage. Adjustable, smoothly finished, nasal tips for maximum patient comfort. Soft funnel shaped
connector to facilitate easy connection to oxygen source. Oxygen tube length: approximately 2m.
Tube used to deliver oxygen through the nose. Material: PVC. Automatic, open distal (patient) end, with 6 to 12 lateral eyes. Proximal end with
Oxygen tube, extension connector enabling the tube to be connected to an oxygen supply tube of any diameter (e.g. serrated male conical tip). Sterile, for single patient use.
Diameter: CH 10. Length: 40cm

e) SIMV Respiratory Rate: up to 40 breaths per minute.
• ISO 13485:2003 Medical devices -- Quality

f) CPAP/PEEP up to 20 cm H2O.
management systems -- Requirements for regulatory
g) Pressure support up to 45 cm H2O.
purposes (Australia, Canada and EU)
h) FiO2 between 21 to 100 %
• ISO 14971:2007 Medical devices -- Application of risk
i) Inspiratory and expiratory times up to at least 2 sec and 8 sec respectively
management to medical devices IEC 60601-1:2012
j) I:E Ratio at least from 1:1 to 1:3.
Medical electrical equipment - Part 1: General
2 Modes of ventilation:
requirements for basic safety and essential performance
a) Volume controlled.
• IEC 60601-1-1:2000 Medical electrical equipment - Part
b) Pressure controlled.
Portable ventilator 1-1: General requirements for safety - Collateral standard:
c) Pressure support.
Safety requirements for medical electrical systems
d) Synchronized intermittent mandatory ventilation (SIMV) with pressure support.
• IEC 60601-1-2:2007 Medical electrical equipment - Part
e) Assist / control mode
1-2: General requirements for basic safety and essential
f) CPAP/PEEP
performance - Collateral standard: Electromagnetic
Alarms required: FiO2, minute volume, pressure, PEEP, apnoea, occlusion, high
compatibility - Requirements and tests
respiration rate, disconnection
• ISO 80601-2-12:2011 Medical electrical equipment --
System alarms required: power failure, gas disconnection, low battery, vent inoperative,
Part 2-12: Particular requirements for basic safety and
self diagnostics
essential performance of critical care ventilators
If alarm silencing feature is incorporated, it must be temporary and clearly displayed when
activated
Compact portable device measures arterial blood oxygen saturation (SpO2), heart rate
and signal strength. Measuring range: SpO2 30 to 100% (minimum graduation 1%), Heart
rate 20 to 250 bpm (minimum graduation 1bpm). Line-powered, or Extra-
batteries/rechargeable batteries are required at least one year.
Antibiotics According to national guidelines and clinical presentation
Compound Sodium
Lactate Solution


Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach mid-
Gloves, forearm (eg. minimum 280mm total length. Sizes, S, M, L
• ANSI/ISEA 105-2011,
examination
• ASTM D6319-10
Gloves should have long cuffs, reaching well above the wrist, ideally to mid-forearm.
CASE MANAGEMENT
• or equivalent

Gloves, surgical, length to Gloves, surgical, nitrile, powder-free, single use.
• ANSI/ISEA 105-2011,
• ASTM 6319-10
examination gloves) Gloves should have long cuffs, reaching well above the wrist, ideally to mid-forearm.
• or equivalent
resistant (preferable), Completely cover the sides and length of the face, May be re-
or equivalent
usable (made of robust material which can be cleaned and disinfected) or disposable.

shaped)
equivalent

or equivalent;
Mask,
should be clearly identified, structured design that does not collapse against the mouth on ASTM F1862-07, ISO 22609, or equivalent
surgical
(e.g. duckbill, cup-shaped) • Breathability: MIL–M-36945C, EN 14683 annex C, or
equivalent
equivalent

Gown colours preferable to better detect possible contamination, thumb/finger loops or elastic • Option 2: blood borne pathogens penetration resistant:
cuff to anchor sleeves in place. AAMI PB70 level 4 performance, or (EN 14126-B) and
equivalent
Good seal with the skin of the face, Flexible PVC frame to easily fit with all face contours
with even pressure, Enclose eyes and the surrounding areas, Accomodate wearers with • EU standard directive 86/686/EEC, EN 166/2002,
Goggles, prescription glasses, Clear plastic lens with fog and scratch resistant treatments, • ANSI/ISEA Z87.1-2010,
protective Adjustable band to secure firmly so as not to become loose during clinical activity, Indirect or equivalent
venting to avoid fogging, May be re-usable (provided appropriate arrangements for
decontamination are in place) or disposable.
Bio-hazardous bag

• 6 handles
Body bag

SARS Disease Commodity Packages
Agent's Biosafety Level: BSL2, virus culture BSL3 Severe Acute Respiratory Syndrome (SARS) [LINK]
Epidemic Potential: High Last Update: 21 September 2018
Immunoassay Culture
Even in inter-epidemic periods, SARS outbreak remains a distinct (PCR)
possibility. Whether transmission is through animal-to-human Upper and lower respiratory samples Several ELISA Non- viral transport medium
contact or human-to-human contact, immediate sample collection (nasophyrangeal and sputum samples), blood 1 RT-PCR prequalified (NPQ) required
and diagnosis is critical to responding to any SARS outbreak. Non-prequalified (NPQ) Confirmation via several in-house
microneutralization ELISA/IF tests
PREVENTION & CONTROL Travel & Trade Vaccine Infection Protection & Control (IPC)
Personal Protective Equipment (PPE) for screening

Use of PPE at at-risk health facilities
There are numerous potential hosts of SARS. Due to the
Temperature screening at Several candidates in development.
uncertainty and difficulty in diagnosing SARS accurately and timely,
airports/entry points of affected Please refer to the most recent
it is recommended that proper IPC precautions, similar to Influenza
countries guidance in the R&D Blueprint
and MERS-CoV, be undertaken. PPE Guidelines
[LINK]
Please see WHO guidance on SARS [LINK]

CASE MANAGEMENT Treatment Personal Protection Equipment (PPE)

Oxygen Therapy
Respiratory (standard, droplet IPC); Airborne
Mechanical Ventilation of severe
There is no proven specific treatment or vaccine, however there are precautions for aerosol generating procedures,
cases (40%)
ongoing R&D efforts. PPE is required to protect those in contact Several candidates Antibiotics, Home Care Kits for home isolation of
Use of Oximeter highly
with infected and potentially infected patients. in development. Pain/Fever asymptomatic cases or mildly symptomatic (in the
recommended
case of a large outbreak)
Intubation, ICU, ECMO required for
severe patients
• Supportive treatment (oxygen, antibiotics, hydration & fever/pain relief) to reduce mortality

Sample Collection

SURVEILLANCE
Puncture resistant container for collection and disposing of used, disposable and
Sharps container boxes auto-disable syringes, needles. 5 L capacity accommodating approximately 100
syringes. Boxes prominently marked.
Sputum Collection Sputum collection container, 30ml, 5.7x3.5cm, with screw cap, autoclavable, polypropylene.
Diagnostics
Criteria for selection of specific diagnostic tests may include historical efficacy, adherence to any existing Target Product Profiles, ease of use, necessary throughput,
distribution and logistics requirements, and manufacturer production capacity. For some pathogens, consideration may need to be given to the presence of mutations in
targeted gene sequences or proteins. WHO can advise on the selection of tests on a case by case basis as determined by a specific event.
• ISO 80601-2-56:2009
• ISO 80601-2-59 Ed. 1.0:2008
Travel & Trade
• ASTM E1104-98(2003)
Handheld battery-powered electronic instrument designed to estimate body • ASTM E1965-98(2009)
temperature od a site on skin (e.g. forehead) non-invasively, quickly without • ASTM E1112-00(2011)
Thermometer, Infrared
touching. A sensor can be cleaned easily by each use with wiping by disinfectant • JIS T 4207:2005
or sterilisable cover. • or equivalent
Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach

mid-forearm (eg. minimum 280mm total length. Sizes, S, M, L • EU standard directive 93/42/EEC Class I, EN 455,
Gloves,
examination
TROL
OSL | Disease Commodity Packages 24 SARS

SARS
Disease Commodity Packages

IPC PPE - Screening
examination gloves)

High fluid resistance, Good breathability, Internal and external faces should be
particulate respirator, grade • Fluid resistant surgical N95 respirator with minimum 80 mm
clearly identified, Structured design that does not collapse against the mouth (e.g.
N95 or higher Hg pressure based on ASTM F1862, ISO 22609 , or
duckbill, cup-shaped)
equivalent

Single use, fluid resistant, disposable, length mid-calf to cover the top of the or equivalent
Gown boots, light colours preferable to better detect possible contamination, • Option 2: blood borne pathogens penetration resistant:
thumb/finger loops or elastic cuff to anchor sleeves in place. AAMI PB70 level 4 performance, or (EN 14126-B) and
equivalent
Device concentrates oxygen from ambient air. On 4 antistatic swivel castors, 2 with brakes. Integrated WHO Core:
handle allows for easy moving and positioning. Oxygen sensing device is integrated and measures [LINK]
Concentrator, Oxygen
concentration at flow meter entrance. Four-step filtering of air-intake, including bacterial filter. All filters
Oxygen concentrators replaceable, coarse filter washable/reusable. Continuous monitoring with visual and audible alerts, on low
'high output pressure, low oxygen concentration, power failure and battery test. Operating conditions:
Temperature between 5 to 45 degrees Celsius, Relative humidity max. 90% without condensation. Spare Oxygen Concentrator
[LINK]
parts should be required for operating at least one year. Technical Guidelines
(Oxygen concentrator) Flow Splitter of oxygen flow provided by an oxygen concentrator. Each flow can be adjusted individually via its flow meter, range: 0.125 to 2LPM
splitter (Liter Per Minute). The output nozzle can either be fit with tubing or left blank. Input pressure: 50 to 350kPa.
Nasal prongs (nasal cannula) is a device designed for easy administration of oxygen and comfort of patient. The device consists of a plastic
Oxygen prongs, nasal, non- tube which fits behind the ears, and a set of two prongs which are placed in the nostrils. Soft twin prongs nasal tips to ensure equal oxygen flow
sterile, single use to both.Star lumen main tube to avoid accidental blockage. Adjustable, smoothly finished, nasal tips for maximum patient comfort. Soft funnel
shaped connector to facilitate easy connection to oxygen source. Oxygen tube length: approximately 2m.

e) SIMV Respiratory Rate: up to 40 breaths per minute.
• ISO 13485:2003 Medical devices -- Quality management
f) CPAP/PEEP up to 20 cm H2O.
systems -- Requirements for regulatory purposes (Australia,
g) Pressure support up to 45 cm H2O.
Canada and EU)
h) FiO2 between 21 to 100 %
• ISO 14971:2007 Medical devices -- Application of risk
i) Inspiratory and expiratory times up to at least 2 sec and 8 sec respectively

management to medical devices IEC 60601-1:2012
j) I:E Ratio at least from 1:1 to 1:3.
Medical electrical equipment - Part 1: General requirements
2 Modes of ventilation:
for basic safety and essential performance
a) Volume controlled.
• IEC 60601-1-1:2000 Medical electrical equipment - Part 1-
b) Pressure controlled.
Portable ventilator 1: General requirements for safety - Collateral standard:
c) Pressure support.
Safety requirements for medical electrical systems
d) Synchronized intermittent mandatory ventilation (SIMV) with pressure support.
• IEC 60601-1-2:2007 Medical electrical equipment - Part 1-
e) Assist / control mode
2: General requirements for basic safety and essential
f) CPAP/PEEP
performance - Collateral standard: Electromagnetic
Alarms required: FiO2, minute volume, pressure, PEEP, apnoea, occlusion, high
compatibility - Requirements and tests
respiration rate, disconnection
• ISO 80601-2-12:2011 Medical electrical equipment -- Part
System alarms required: power failure, gas disconnection, low battery, vent
2-12: Particular requirements for basic safety and essential
inoperative, self diagnostics
performance of critical care ventilators
If alarm silencing feature is incorporated, it must be temporary and clearly
displayed when activated
Compact portable device measures arterial blood oxygen saturation (SpO2), heart
rate and signal strength. Measuring range: SpO2 30 to 100% (minimum
graduation 1%), Heart rate 20 to 250 bpm (minimum graduation 1bpm). Line-
powered, or Extra-batteries/rechargeable batteries are required at least one year.
Antibiotics According to national guidelines and clinical presentation

Solution

Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably reach

mid-forearm (eg. minimum 280mm total length. Sizes, S, M, L • EU standard directive 93/42/EEC Class I, EN 455,
Gloves,
examination

examination gloves)
patient, Adjustable band to attach firmly around the head and fit snuggly against • EU standard directive 86/686/EEC, EN 166/2002,
CASE MANAGEMENT
Face shield the forehead, Fog resistant (preferable), Completely cover the sides and length of • ANSI/ISEA Z87.1-2010,
the face, May be re-usable (made of robust material which can be cleaned and or equivalent
disinfected) or disposable.
• Option 1: blood and body fluid penetration resistant: meets

or exceeds ISO 16603 class 3 or above exposure pressure,
or equivalent
Coverall thumb/finger loops to anchor sleeves in place, good freedom of movement. Sizes:
• Option 2: blood-borne pathogens penetration
M, L, XL

particulate respirator, grade • Fluid resistant surgical N95 respirator with minimum 80 mm
clearly identified, Structured design that does not collapse against the mouth (e.g.
N95 or higher Hg pressure based on ASTM F1862, ISO 22609 , or
duckbill, cup-shaped)
equivalent

or equivalent;
Medical/surgical mask, high fluid resistance, good breathability, internal and • Fluid resistance at minimum 120 mmHg pressure based on
Mask,
external faces should be clearly identified, structured design that does not ASTM F1862-07, ISO 22609, or equivalent
surgical
collapse against the mouth (e.g. duckbill, cup-shaped) • Breathability: MIL–M-36945C, EN 14683 annex C, or
equivalent
equivalent

equivalent
Single use, fluid resistant, adjustable and should stay securely in place once adjusted, facial opening constructed without elastic, cover reaches
Head cover
upper part of the gown
Non-slip sole pattern, PVC or polyurethane sole which is completely sealed and waterproof, Knee-high in order be higher than the bottom edge
Boot, rubber of the gown, Range of sizes available to improve comfort and avoid trauma to the feet, Materials of construction include rubber, PVC, neoprene,
nitrile, polyurethane, Favor light colours to better identify possible contaminations.

disposable.
Apron, disposable or single use, made of polyester with PVC-coated, or other waterproof material, Straight apron with bib, minimum basis
Apron weight: 250g/m2, waterproof,
Bio-hazardous bag
• 6 handles
Body bag

Meningococcal Meningitis Disease Commodity Packages
Agent's Biosafety Level: BSL2 Meningococcal Meningitis [LINK]

Epidemic Potential: High in Meningitis belt Last Update: 21 September 2018 Managing Epidemics Handbook [LINK]
Polymerase Chain
CSF Sample Rapid Diagnostic Test (RDT) Culture
Reaction (PCR)
If RDTs are positive for a vaccine preventable serogroup, verification

of serogroup by PCR or culture is recommended before a decision is If PCR is locally available
Lumbar puncture kit; transport media (trans- 1 RDT available Reagents for
taken to initiate a vaccine response. specfic consumables
isolate) available via WHO Ouagadougou 1 RDT in field trial serogrouping required
might be required
PREVENTION & CONTROL Chemoprophylaxis Vaccine
Outside Meningitis belt: Single dose of Ciprofloxacin (500mg) for close

Polysaccharide: ACWY, ACW
contacts recommended.
Transmission occurs through direct contact by spreading respiratory Conjugate: A, C
and throat secretions. Generaly it takes close or lengthy contact to ACWY
Inside Meningitis belt: In addition single dose of Ciprofloxacin (500mg)
transmit meningococcal menigitis from person to person. available through the ICG mechanism or direct procurement
to village/neighborhood under evaluation.
to manufactors

Meningococcal disease is potentially fatal and should be viewed as a
medical emergency. Admission is necessary for diagnosis and
treatment. Antimicrobial therapy is essential and should be combined Standard Precaution
IV Fluids
with supportive treatment. Contagiousness of patients is moderate Ceftriaxone IV / IM
Pain & Fever
and disappears quickly following antimicrobial treatment, hence
isolation is not necessary.
[LINK]

• Chemoprophylaxsis to reduce transmission
• Adhesive wound plaster with antiseptic pad, skin coloured, hypoallergenic, packed individually, pack with 2 sizes - 2x7cm and 2.5x7cm
• Gauze swab 10x10cm, 100% cotton, 12-ply, 17 threads, sterile, per 2 pieces in a wrapper x 4
• Disinfecting swab, impregnated with 70% isopropyl- alcohol x 1
• Spinal needle 18G x 3.5", sterile, disposable. Fine Quincke bevel, colour code pink x 2
• Spinal needle 22G x 1.5", sterile, disposable. Fine Quincke bevel, colour code black x 2
Lumbar Puncture Kit
• Operation gloves size 7.5, anatomically shaped, sterile, disposable, latex x 2
• Povidone iodine 10%, 10ml x 2
• Vacutainer vacuum tube 75x13mm, 4.0ml, without additive, for serum determination x 2
• Zip-lock bag 20x20cm x 1
Sample Collection
• Self-adhesive labels, 21.2x19mm white, per series of 10 printed N8K01VZO to N8K01VZX and numbered from 20030001 to 200301050 x 1
SURVEILLANCE
• Spinal needle 22Gx1.5" (0,7x38mm), fine Quincke bevel, colour code black, sterile, disposable
• Spinal needle 18Gx3.5" (1.25x90mm), fine Quincke bevel, colour code pink, sterile, disposable
• Vacutainer blood collection tube, 75x13mm, 4ml, siliconized plastic tube, without further additives, for serum determination. With red
Hemogard closure, vacuum, sterile
• Gauze swab, 10x10cm, 12-ply, 17 threads, sterile, packed individually
Field Sample Kit - Module,
• Surgical gloves, size 7.5, anatomically shaped, latex, sterile, disposable. As per ASTM 3577 FDA 510(K)
Collection of Cerebro Spinal
• Adhesive wound plaster with antiseptic pad, 2 sizes (2x7cm and 2.5x7cm) skin-coloured, hypoallergenic, individually packed
Fluids (CSF) Samples
• Povidone iodine 10%,10ml.
• Disinfecting swab, impregnated with 70% isopropyl alcohol
• Drug bag, 20x20cm, plastic, re-closable
• Self-adhesive labels 22X18mm SHEET/20 1
• Air bubble envelopes abt 17.5x20cm EACH 20
Diagnostics
OSL | Disease Commodity Packages 28 MENINGITIS

Meningococcal Meningitis Disease Commodity Packages
Chemoprohylaxsis
Ciprofloxacine Ciprofloxacine, 500mg, tablet
• 10 µg of purified Men A polysaccharide antigen conjugated with tetanus toxoid (PsA-TT) per dose
MenAfriVac
• Ages 1 - 29 years old
Vaccine
• 5 µg of PsA-TT per dose

MenAfriVac 5 µg • Ages 3 months to 24 months
• Conjugate vaccine is immunogenic in a 1-dose schedule for those aged 9 - 24 months or 2 dose schedule for those aged 3 - 9 months
Aetiological
Treatment
Ceftriaxone Ceftriaxone, powder for injection, 1g, vial
Water for injection Water for injection, 10ml ampule

Solution
Supportive
Treatment

Gloves,
examination
CASE MANAGEMENT

PPE Standard Precaution

examination gloves)

clearly identified, Structured design that does not collapse against the mouth
(e.g. duckbill, cup-shaped)
equivalent

equivalent
OSL | Disease Commodity Packages 29 MENINGITIS

Yellow Fever Disease Commodity Packages
Agent's Biosafety Level: BSL3 Yellow Fever [LINK]

Epidemic Potential: Medium Last Update: 21 September 2018 Managing Epidemics Handbook [LINK]
Immunoassay
Difficult to diagnose, especially in its early stages, yellow fever can be (PCR)
confused with severe malaria, dengue hemorrhagic fever,
leptospirosis, viral hepatitis and other hemorrhagic fevers. Blood tests
can detect yellow fever antibodies while several other techniques can Blood sample, Liver biopsy
be used to identify the virus in blood specimens or liver tissue Several ELISA IgM/IgG (NPQ)
1 RT-PCR (NPQ)
collected after death. However, these tests require trained staff and In-house ELISA IgM/IgG by CDC
specialized equipment and materials.
PREVENTION & CONTROL Vector Control Vaccine Infection Protection & Control (IPC)
Vaccination is the most important means of preventing yellow fever. In

high-risk areas where vaccination coverage is low, prompt recognition
and control of outbreaks using mass immunization is critical for
YF17D
preventing epidemics. The main contribution of vector control in the Vector control of larvae and adult in urban
available through the ICG mechanism or direct
arsenal of public health measures is to control YF epidemics in urban settings Vaccination cards
procurement to manufactors
centres where transmission is occurring readily between mosquitoes, Measures of personal protection against Mosquito nets
(See Yellow Fever link above for more
namely Aedes aegypti, and humans. Control efforts need to target mosquito bites are recommended
information)
both mosquito larvae and adults. Epidemic vector control should be
implemented as quickly as possible in neighbourhoods and districts
where YF cases live.

Supportive
Good and early supportive treatment in hospitals improves survival
rates. There is currently no specific anti-viral drug for yellow fever but
Standard Precaution,
specific care to treat dehydration, liver and kidney failure, and fever
IV Fluids, Pain & Fever, severe cases (15-20%) mosquito net for patients
improves outcomes. Associated bacterial infections can be treated
with antibiotics.

• Vector Control
• Personal Protection against mosquito bites to reduce morbidity

Tubes, blood collection, Vacuum tube used for blood collection with EDTA, sterile, capped with
Sample Collection
EDTA vacuum seal. Material: plastic. 4 ml and 6 ml

SURVEILLANCE
Tubes, blood collection, Vacuum tube used for serum collection, sterile, capped with vacuum seal.
serum Material: plastic. 4 ml and 6 ml
Tubes, blood collection, Vacuum tube used for plain/dry blood collection without anticoagulant,
plain/dry sterile, capped with vacuum seal. Material: plastic. 4 ml and 6 ml
Puncture resistant container for collection and disposing of used, disposable

Sharps container boxes and auto-disable syringes, needles. 5 L capacity accommodating
approximately 100 syringes. Boxes prominently marked.
Diagnostics
OSL | Disease Commodity Packages 30 YELLOW FEVER

WHOPES recommended insecticides:

• Deltamethrin UL, or
WHOPES recommended • Deltamethrin EW, or
insecticides for space • Lambda-cyhalothrin EC, or
spraying (in- & out-door) • Malathion EW and UL, or
• Permethrin (25 cis:75 trans; 10.35% w/w) + s-bioallethrin (0.14 w/w)+ piperonyl butoxide (9.85% w/w)EW, or
• d-d, trans-cyphenothrin EC
WHOPES recommended compunds for control of mosquito larvae:

• Bacillus thuringiensis israelensis, strain AM65-52 (3000 ITU/mg), WG, or
• Bacillus thuringiensis israelensis, strain AM65-52 (3000 ITU/mg), GR, or
• Bacillus thuringiensis israelensis (strain AM65-52 + B. sphaericus strain ABTS-1743; 50 Bsph ITU/mg), GR, or
• Chlorpyrifos EC, or
• Diflubenzuron DT, GR, WP, or
WHOPES recommended • Novaluron EC, or
Vector Control
compunds for control of • Pyriproxyfen GR, or

mosquito larvae • Pyriproxyfen 2 MR, or

• Fenthion EC, or
• Pirimiphos-methyl EC, or
• Temephos EC, GR, or
• Spinosad DT, EC, GR, SC, or
• Spinosad 83.3 monolayer DT, or
• Spinosad 25 extended relaease GR
Hudson X-Pert, 3 gallon or

11.4 ltr tank
Micron, 11.4 ltr tank,

http://www.microngroup.com/
WHOPES recommended Sprayer Equipment
files/cs10__cs14_v2.pdf
Control flow valves, 1.5 bar,

red color
Ceramic nozzle (8002E)

Vaccine
YF 17D Live, attenuated viral vaccines, Single dose, 0.5ml
Vaccination cards Yellow Fever Vaccination Card

IPC
Mosquito net LLIN, 110-150d, mosquito net, polyethylene 110-150 DENIER, treated with WHOPES recommended insecticide

Solution
Paracetamol Paracetamol, 500mg, tabs
Paracetamol IV Paracetamol 10mg/ml solution, 100ml vial

Gloves,
examination
mid-forearm. Inner glove should be worn under the cuff of the • ASTM D6319-10
CASE MANAGEMENT
gown/coveralls (and under any thumb/finger loop) whereas the outer glove • or equivalent
should be worn over the cuff of the gown/coveralls.
PPE - Standard Precaution

mid-forearm. Inner glove should be worn under the cuff of the • ASTM 6319-10
examination gloves)
gown/coveralls (and under any thumb/finger loop) whereas the outer glove • or equivalent
should be worn over the cuff of the gown/coveralls. Sizes 5 to 8.5
Face mask,
High fluid resistance, Good breathability, Internal and external faces should equivalent
be clearly identified, Structured design that does not collapse against the • Fluid resistant surgical N95 respirator with minimum 80 mm Hg
N95 or higher
mouth (e.g. duckbill, cup-shaped) pressure based on ASTM F1862, ISO 22609 , or equivalent


performance, or AAMI PB70 level 3 performance or above, or
Single use, fluid resistant, disposable, length mid-calf to cover the top of the
equivalent
Gown boots, light colours preferable to better detect possible contamination,
• Option 2: blood borne pathogens penetration resistant: AAMI
thumb/finger loops or elastic cuff to anchor sleeves in place.
PB70 level 4 performance, or (EN 14126-B) and partial body
protection ( EN 13034 or EN 14605), or equivalent

Shigellosis Disease Commodity Packages
Agent's Biosafety Level: BSL2

Epidemic Potential: High Last Update: 21 September 2018
A definitive diagnosis of Shigella infection can only be made by Polymerase Chain Reaction
Culture
isolating the organism from stool and serotyping the isolate. Culture (PCR)
is also required to determine antimicrobial sensitivity. Although
sensitive molecular techniques to detect Shigella, such as PCR, Stool or rectal swab, transport media (Cary-
have been developed, they are not yet practical for routine use and Blair) Several PCRs
they do not permit determination of antimicrobial sensitivity. Methods Antiserum and AMS required
Non-prequalfied (NPQ)
to detect Shigella in food and in the environment are not yet
standardized.
PREVENTION & CONTROL Vaccine WASH Safe and dignified burial
Shigella are spread by direct contact with an infected person, or by

eating contaminated food or drinking contaminated water. Flies may Personal Protective Equipment (PPE) +
Safety of water sources (chlorination, flitration, Disinfection supplies (IPC)
also transmit the organism. The low infective dose, as few as 200 R&D
etc.); household water treatment
viable organisms, facilitates person-to-person spread. Humans and a
few primates are the only reservoir of Shigella. PPE Guidelines [LINK]
CASE MANAGEMENT Treatment

All cases of bloody diarrhoea should be treated promptly with an
antimicrobial that is known to be effective against Shigella. This
lessens the risk of complications and death, shortens the duration of
symptoms, and hastens the elimination of Shigella from the stool. Ciprofloxacine + Zinc for pediatrics
Fluids
Other supportive measures used to treat acute diarrhoea, such as [take local antimicrobial sensitivities into account]
rehydration and zinc supplementation should also be provided.

• Supportive treatment (hydration) to reduce mortality

Sample Collection
Swabs CultureSwab, Cary-Blair Agar, single swab

SURVEILLANCE
Faeces collection container 125ml with screw cup

Diagnostics
• Kit water tank, 5 m3, flexible 1 acc.2" DIN50

• Water distribution module, 2 ramps x 6 taps
• Hoses module, 2'' DIN 50 + coupling
WASH
• Tester, pool tester

Safe Water Module
• Phenol red tablets for cholrine testing
• NaDCC, granules, 1kg, 65 to 70% + dossage spoon (contingent upon necessary concentration levels)
Chlorine NaDCC, granules, 1kg, 65 to 70% + dossage spoon

IPC
Bar soap
OSL | Disease Commodity Packages 32 SHIGELLOSIS

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Operational Support & Logistics

Ebola Virus Disease Disease Commodity Packages

Agent's Biosafety Level: BSL4 Ebola Virus Disease [LINK]

CASE MANAGEMENT Treatment Personal Protective Equipment (PPE)

Key outbreak control activities considered for material supply

• Rapid diagnostics tests to improve disease identification

INTERVENTION COMMODITY TECHNICAL DESCRIPTION

WHO Core - Thermometers, electronic, infrared [LINK]

OSL | Disease Commodity Packages 1 EBOLA VIRUS DISEASE

Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably

Gloves, surgical, nitrile, powder-free, single use.

forearm large (longer than

• Option 1: fluid penetration resistant: EN 13795 high performance, or

• EU standard directive 89/686/EEC Category III,

and puncture, or above

• Option 1: blood and body fluid penetration resistant: meets or

Straight apron with bib,

OSL | Disease Commodity Packages 2 EBOLA VIRUS DISEASE

Compound Sodium Lactate

Paracetamol Paracetamol, 500mg, tablets

Gloves, examination, nitrile, powder-free, non-sterile. Cuff length preferably

Gloves, surgical, nitrile, powder-free, single use.

• Option 1: blood and body fluid penetration resistant: meets or

EN 14683 Type IIR performance

OSL | Disease Commodity Packages 3 EBOLA VIRUS DISEASE

• Option 1: fluid penetration resistant: EN 13795 high performance, or

Alcohol-based hand rub bottle of 100ml

Sprayer, hand-held 1,5 liters, acid resistant

Sprayer, backpack 12 liters, acid resistant

Chlorine NaDCC, granules, 1kg, 65 to 70% + dossage spon

OSL | Disease Commodity Packages 4 EBOLA VIRUS DISEASE

Agent's Biosafety Level: BSL4 Marburg Virus Disease [LINK]

CASE MANAGEMENT Treatment Personal Protective Equipment (PPE)

Key outbreak control activities considered for material supply

INTERVENTION COMMODITY TECHNICAL DESCRIPTION

OSL | Disease Commodity Packages 5 MARBURG VIRUS DISEASE

Gloves, surgical, nitrile, powder-free, single use.

"Surgical N95 respirator" cleared by the US FDA and

• Option 1: fluid penetration resistant: EN 13795 high

• EU standard directive 89/686/EEC Category III,

"Surgical N95 respirator" cleared by the US FDA and

• Option 1: blood and body fluid penetration resistant:

Straight apron with bib,

OSL | Disease Commodity Packages 6 MARBURG VIRUS DISEASE

Compound Sodium Lactate

Paracetamol Paracetamol, 500mg, tablets

Gloves, surgical, nitrile, powder-free, single use.

• Option 1: blood and body fluid penetration resistant:

"Surgical N95 respirator" cleared by the US FDA and

EN 14683 Type IIR performance

• Filtration efficiency: ASTM F2101, EN14683 annex B, or

OSL | Disease Commodity Packages 7 MARBURG VIRUS DISEASE

• Option 1: fluid penetration resistant: EN 13795 high

Alcohol-based hand rub Bottle of 100ml

Sprayer, hand-held 1,5 liters, acid resistant

Sprayer, backpack 12 liters, acid resistant

Chlorine NaDCC, granules, 1kg, 65 to 70% + dossage spon

OSL | Disease Commodity Packages 8 MARBURG VIRUS DISEASE

Agent's Biosafety Level: BSL4 Lassa Fever [LINK]

Polymerase Chain Reaction (PCR) Immunoassay

CASE MANAGEMENT Treatment Personal Protective Equipment (PPE)

Key outbreak control activities considered for material supply

• Rapid diagnostics tests to improve disease identification