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TCM Treatment of Influenza and Viral

Infections
By

John Chen
Pharm.D., Ph.D., O.M.D., L.Ac.

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Chinese Herbology and
Pharmacology 张仲景 Zhāng Zhòng-Jĭng, 150-219 CE

John K. Chen, Ph.D., Pharm.D., O.M.D., L.Ac. • 伤寒杂病论 Shang


Han Za Bing Lun
Evergreen Herbs (Discussion of Cold-
Tel: (626) 810-5530 Fax (626) 810-5534 Induced Disorders and
W b it www.evherbs.com
Website: h b
Email: john.chen@evherbs.com Miscellaneous
Diseases)
Lotus Institute Of Integrative Medicine
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Email: info@eLotus.org

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张仲景 Zhāng Zhòng-Jĭng, 150-219 CE 张仲景 Zhāng Zhòng-Jĭng, 150-219 CE

• 伤寒论 • 金匮要略 • 伤寒论 Shang Han Lun (Discussion of


Shang Han Lun Jin Gui Yao Lue Cold-Induced Disorders)
(Discussion of (Essentials from the – Taiyang
Cold-Induced
Cold Induced Golden Cabinet) – Yangming
Disorders) – Shaoyang
– Taiyin
– Shaoyin
– Jueyin
• •

吴有性 Wū Yŏu-Xìng, 1580’s-1660’s

• 温疫论 Wen Yi Lun


(Discussion of
Epidemic Warm
Disease), 1642

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温热论 Wen Re Lun
(Discussion of Warm and Hot Disorders)
叶桂 Yè Guì, 1666-1745

• wen yi (warm epidemic) are “not caused by wind, • 温热论 Wen Re Lun
cold, summer-heat, nor dampness, but rather by (Discussion of Warm
戾气 li qi (perverse qi).” and Hot Disorders)
• He further elaborated that li qi (perverse qi)
existed
i t d iin th
the universe,
i b
butt h
have ““no sound
d nor
smell, and no shape nor shadow.”
• Lastly, he observed that li qi (perverse qi) may be
transmitted from one person to another via
“heaven [air borne]” or “earth [direct contact],”
and affect weak, deficient individuals (i.e., those
with low immunity).

叶桂 Yè Guì, 1666-1745 吴塘 Wú Táng, 1758-1836

• Wei Qi Ying Xue Bian Zheng • 温病条辨 Wen Bing


Tiao Bian (Systematic
(Defensive, Qi, Nutritive, Blood
Differentiation of
Differentiation) Warm Disease), 1798
– wei (defensive) level
– qi (energy) level
– ying (nutritive) level
– xue (blood) level

吴塘 Wú Táng, 1758-1836 Shang Han (Cold Damage)

• San Jiao Bian Zheng (Triple Burner • Taiyang


Differentiation) – Ma Huang Tang (Ephedra Decoction)
– Gui Zhi Tang (Cinnamon Twig Decoction)
– Upper jiao
– Ge Gen Tang (Kudzu Decoction)
– Middle
Middl jiao
ji
– Lower jiao

• •

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Ma Huang Tang (Ephedra Decoction) Ma Huang Tang (Ephedra Decoction)

• Ma Huang (Herba Ephedrae) • Exterior-excess, wind-cold syndrome: aversion to


• Gui Zhi (Ramulus Cinnamomi) cold, fever, headache, neck stiffness, body aches
and pains, absence of perspiration, dyspnea, a thin,
• Ku Xing Ren (Semen Armeniacae Amarum) white tongue coating, and a superficial, tight pulse.
• Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae • Fever, upper respiratory tract infection, common cold,
Praeparata cum Melle) influenza, bronchitis, pneumonia, asthma, wheezing
and dyspnea, cough, peripheral neuropathy,
enuresis, mastitis, anhidrosis, allergic rhinitis, and
acute nephritis.

Gui Zhi Tang (Cinnamon Twig Decoction) Gui Zhi Tang (Cinnamon Twig Decoction)

• Gui Zhi (Ramulus Cinnamomi) • Exterior-deficient, wind-cold syndrome: headache,


• Bai Shao (Radix Paeoniae Alba) fever, perspiration, aversion to wind, nasal
congestion, dry heaves, absence of thirst, a thin,
• Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae white tongue coating, and a superficial and moderate,
Praeparata cum Melle) or superficial
fi i l and
d weak k pulse.
l
• Sheng Jiang (Rhizoma Zingiberis Recens) • Fever, common cold, influenza, respiratory tract
• Da Zao (Fructus Jujubae) infections, allergic rhinitis, bronchial asthma,
atrioventricular block, testicular pain, hernia,
appendicitis, sciatica, allergic purpura, itching,
frostbite, eczema, urticaria, enuresis, and
hyperactivity disorder.

Ge Gen Tang (Kudzu Decoction) Ge Gen Tang (Kudzu Decoction)

• Ge Gen (Radix Puerariae Lobatae) • Taiyang syndrome with wind-cold invasion: severe
• Ma Huang (Herba Ephedrae) muscle stiffness of the neck and back, aversion to
cold, with or without fever, aversion to wind, absence
• Gui Zhi (Ramulus Cinnamomi) of perspiration, and diarrhea.
• Bai Shao (Radix Paeoniae Alba) • Fever, common cold, influenza, infectious parotitis,
• Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae upper respiratory tract infection, allergic rhinitis,
Praeparata cum Melle) chronic rhinitis, neck and shoulder stiffness and pain,
• Sheng Jiang (Rhizoma Zingiberis Recens) periarthritis of shoulder, tendonitis or bursitis of the
shoulders, soft tissues injuries, facial paralysis, Bell’s
• Da Zao (Fructus Jujubae) palsy, meningitis, encephalitis, tension headache,
scleroderma, urticaria, and diarrhea.

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Shang Han (Cold Damage) Bai Hu Tang (White Tiger Decoction)

• Yangming • Shi Gao (Gypsum Fibrosum)


– Bai Hu Tang (White Tiger Decoction) • Zhi Mu (Rhizoma Anemarrhenae)
– Bai Hu Jia Ren Shen Tang (White Tiger plus • Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae
Ginseng Decoction) Praeparata cum Melle)
• Geng Mi (Semen Oryzae)

Bai Hu Jia Ren Shen Tang


Bai Hu Tang (White Tiger Decoction)
(White Tiger plus Ginseng Decoction)
• Yangming jing (channel) syndrome; excess heat in • Shi Gao (Gypsum Fibrosum)
the yangming qi (energy) level: high fever, flushed • Zhi Mu (Rhizoma Anemarrhenae)
face, irritability, thirst with a strong desire to drink,
profuse sweating, and aversion to heat. The pulse is • Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae
either
ith surging,
i big
bi and d forceful;
f f l or the
th pulse
l isi Praeparata cum Melle)
slippery and rapid. • Geng Mi (Semen Oryzae)
• High fever, bacterial or viral infections, common cold, • Ren Shen (Radix et Rhizoma Ginseng)
influenza, encephalitis, meningitis, pneumonia, lobar
pneumonia, epidemic hemorrhagic fever, heat stroke,
periodontitis, gingivitis, rheumatism, and diabetes
mellitus.

Bai Hu Jia Ren Shen Tang Xiao Xian Xiong Tang


(White Tiger plus Ginseng Decoction) (Minor Sinking into the Chest Decoction)
• Yangming jing (channel) syndrome or excess heat in • Gua Lou (Fructus Trichosanthis)
the yangming qi (energy) level with qi and body fluid • Huang Lian (Rhizoma Coptidis)
deficiencies: high fever, flushed face, irritability, a dry
mouth, thirst with a strong desire to drink, profuse • Ban Xia (Rhizoma Pinelliae)
sweating,
ti aversion
i tto coldld iin th
the upper b
back,
k and da
big, forceless pulse.
• Bacterial or viral infections, influenza, encephalitis,
meningitis, lobar pneumonia, febrile disorders, heat
stroke, periodontitis, gingivitis, diabetes mellitus, and
dry mouth and throat.

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Xiao Xian Xiong Tang
温病 Wen Bing (Warm Disease)
(Minor Sinking into the Chest Decoction)
• Phlegm-heat stagnation in the chest: distention and • Yin Qiao San (Honeysuckle and Forsythia
fullness in the chest and epigastric regions with pain Powder)
upon palpation; cough with yellow, sticky sputum; a • Sang Ju Yin (Mulberry Leaf and
yellow, greasy tongue coating; and a slippery, rapid Chrysanthemum Decoction)
pulse.
l • Sha Shen Mai Dong Tang (Glehnia and
• Gastritis, erosive gastritis, acid reflux, epigastric pain, Ophiopogonis Decoction)
reflux esophagitis, acute bronchitis, bronchitis,
pneumonia, silicosis, pulmonary heart disease,
tuberculous pleurisy, pleurisy with effusion, exudative
pleurisy, chronic hepatitis, and cholelithiasis.

Yin Qiao San Yin Qiao San


(Honeysuckle and Forsythia Powder) (Honeysuckle and Forsythia Powder)
• Jin Yin Hua (Flos Lonicerae Japonicae) • Onset of wen bing (warm disease): fever, aversion to
• Lian Qiao (Fructus Forsythiae) cold, slight aversion to wind, slight or absence of
• Jing Jie Sui (Spica Schizonepetae) perspiration, headache, thirst, a sore throat, cough, a
red tongue tip with a thin, white or thin, yellow tongue
• Dan Dou Chi (Semen Sojae Praeparatum) coating,
ti andd a superficial,
fi i l rapidid pulse.
l
• Jie Geng (Radix Platycodonis) • Common cold, influenza, high fever, pneumonia,
• Niu Bang Zi (Fructus Arctii) acute upper respiratory infection, pharyngo-
• Bo He (Herba Menthae) conjunctival fever, tonsillitis, parotitis, canker sores,
• Zhu Ye (Herba Phyllostachys) viral myocarditis, epidemic encephalitis B, and drug-
• Gan Cao (Radix et Rhizoma Glycyrrhizae) induced dermatitis.

Sang Ju Yin (Mulberry Leaf and Sang Ju Yin (Mulberry Leaf and
Chrysanthemum Decoction) Chrysanthemum Decoction)
• Sang Ye (Folium Mori) • Early stage of wind-warmth syndrome: cough,
• Ju Hua (Flos Chrysanthemi) mild fever, and slight thirst.
• Bo He (Herba Menthae) • Common cold, influenza, acute bronchitis, acute
• Lian Qiao (Fructus Forsythiae) tonsillitis, coughing, and other upper respiratory
infections.
• Jie Geng (Radix Platycodonis)
• Ku Xing Ren (Semen Armeniacae Amarum)
• Lu Gen (Rhizoma Phragmitis)
• Gan Cao (Radix et Rhizoma Glycyrrhizae)

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Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine. 5
Sha Shen Mai Dong Tang (Glehnia and Sha Shen Mai Dong Tang (Glehnia and
Ophiopogonis Decoction) Ophiopogonis Decoction)
• Sha Shen (Radix Glehniae seu Adenophorae) • Dryness damaging Lung and Stomach yin: dry
• Mai Dong (Radix Ophiopogonis) throat, thirst, fever, dry coughing, and dry, sticky
• Yu Zhu (Rhizoma Polygonati Odorati) sputum.
• Tian Hua Fen (Radix Trichosanthis) • Atrophic gastritis, epigastric pain, lung cancer,
pneumonia, bronchitis, dry cough, cough and
• Sang Ye (Folium Mori) wheezing in children, and diabetes mellitus.
• Bai Bian Dou (Semen Lablab Album)
• Gan Cao (Radix et Rhizoma Glycyrrhizae)

Pu Ji Xiao Du Yin (Universal Benefit


温病 Wen Bing (Warm Disease)
Decoction to Eliminate Toxin)
• Huang Qin (Radix Scutellariae) • Ban Lan Gen (Radix Isatidis)
• Pu Ji Xiao Du Yin (Universal Benefit
• Huang Lian (Rhizoma Coptidis) • Jie Geng (Radix Platycodonis)
Decoction to Eliminate Toxin) • Niu Bang Zi (Fructus Arctii) • Gan Cao (Radix et Rhizoma
• Lian Qiao (Fructus Forsythiae) Glycyrrhizae)
• Bo He (Herba Menthae) • Chen Pi (Pericarpium Citri
• Jiang Can (Bombyx Reticulatae)
Batryticatus) • Sheng Ma (Rhizoma
• Xuan Shen (Radix Cimicifugae)
Scrophulariae) • Chai Hu (Radix Bupleuri)
• Ma Bo (Lasiosphaera seu • Ren Shen (Radix et Rhizoma
Calvatia) Ginseng)

• •

Pu Ji Xiao Du Yin (Universal Benefit Pu Ji Xiao Du Yin (Universal Benefit


Decoction to Eliminate Toxin) Decoction to Eliminate Toxin)
• Presence of wind, heat, and toxin in the • Epidemic hemorrhagic fever, respiratory
upper jiao and head: redness, swelling and tract infection, common cold, influenza,
pain of the face and head; red and swollen severe sore throat, infectious parotitis,
eyes difficulty in opening the eyes; fever
eyes, fever, acute tonsillitis
tonsillitis, lymphadenitis,
lymphadenitis purulent
aversion to cold, a sore throat, thirst, a dry, inflammation and abscess of the face and
red tongue with a yellow tongue coating, head, erysipelas, herpes, carbuncles,
and a rapid, forceful pulse. boils, testitis, myocarditis, and
conjunctivitis.
• •

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Herbology vs Pharmacology Jin Yin Hua (Flos Lonicerae Japonicae)

• Clears heat • Antibiotic • Clears heat


– Exterior vs Interior – Antibacterial
• Clears heat and
– Excess vs Deficiency – Antiviral
eliminates toxins
– Zangg or Fu organs
g – Antifungal
g
• Antipyretic
• Anti-inflammatory


Chen J and Chen T. Chinese Medical Herbology and Pharmacology. Art of Medicine Press. 2004.

Jin Yin Hua (Flos Lonicerae Japonicae) Jin Yin Hua (Flos Lonicerae Japonicae)

• Antibacterial • Antibacterial: Jin Yin Hua has a broad spectrum


of inhibitory actions against Staphylococcus
• Antiviral
aureus, beta-hemolytic streptococcus, E. coli,
Bacillus dysenteriae, Vibrio cholerae, Salmonella
typhi, Diplococcus pneumoniae, Diplococcus
meningitidis, Pseudomonas aeruginosa, and
Mycobacterium tuberculosis. Chlorogenic acid
and isochlorogenic acid have the strongest
antibiotic effects.
• •• Xin Yi Xue (New Medicine), 1975; 6(3):155.
Chen J and Chen T. Chinese Medical Herbology and Pharmacology. Art of Medicine Press. 2004.
• Jiang Xi Xin Yi Yao (Jiangxi New Medicine and Herbology); 1960;(1):34.

Jin Yin Hua (Flos Lonicerae Japonicae) Lian Qiao (Fructus Forsythiae)

• Antiviral: Shuangkangsu, a cyclic peroxide from Jin Yin • Clears heat


Hua, has significant antiviral activities against influenza
virus and respiratory syncytial. The homosecoiridoid • Clears heat and
alkaloids of Jin Yin Hua have antiviral activity against the eliminates toxins
influenza virus H3N2 (A/Hanfang/359/95) and coxsackie
virus B3. The glucosylated caffeoylquinic acid isomers
from Jin Yin Hua shows inhibitory activity against
coxsackie virus B3.
• Yu DQ, et al. The structure and absolute configuration of Shuangkangsu: a novel natural cyclic peroxide from
Lonicera japonica (Thunb.). J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):851-6.
• Yu Y, et al. Homosecoiridoid alkaloids with amino acid units from the flower buds of Lonicera japonica. J Nat Prod.
2013 Dec 27;76(12):2226-33.
• Yu Y, et al. Glucosylated caffeoylquinic acid derivatives from the flower buds of Lonicera japonica. Acta Pharm Sin
B. 2015 May;5(3):210-4.


Chen J and Chen T. Chinese Medical Herbology and Pharmacology. Art of Medicine Press. 2004.

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Lian Qiao (Fructus Forsythiae) Lian Qiao (Fructus Forsythiae)

• Antibacterial • Antibacterial: The essential oil of Lian Qiao has


demonstrated a broad spectrum of inhibitory effects
against Staphylococcus aureus, Diplococcus
pneumoniae, Bacillus dysenteriae, alpha-hemolytic
streptococcus,
t t beta-hemolytic
b t h l ti streptococcus,
t t
Neisseria catarrhalis, Salmonella typhi, Escherichia
coli, Mycobacterium tuberculosis, Bacillus proteus,
Bordetella pertussis, Corynebacterium diphtheriae,
leptospira, and some dermatophytes and influenza
viruses.
• Shan Xi Xin Yi Yao (New Medicine and Herbology of Shanxi), 1980; 9(11):51.
Chen J and Chen T. Chinese Medical Herbology and Pharmacology. Art of Medicine Press. 2004.

Ban Lan Gen (Radix Isatidis) Ban Lan Gen (Radix Isatidis)

• Clears heat, • Antibacterial


eliminates toxins, • Antitoxin
cools blood and • Antiviral
benefits the throat
• Anti inflammatory
Anti-inflammatory

• •

Ban Lan Gen (Radix Isatidis) Da Qing Ye (Folium Isatidis)

• Antiviral: Ban Lan Gen exerts antiviral effect • Clears heat and
against influenza A virus, seasonal influenza eliminates toxins
virus, human or avian influenza virus, novel • Cools blood and
swine-originating influenza virus, Japanese eliminates maculae
encephalitis virus, adenovirus, herpes simplex
virus, hepatitis B virus, human cytomegalovirus,
swine pseudorabies virus, coxsackie virus B3.
• Hsuan SL, et al. The cytotoxicity to leukemia cells and antiviral effects of Isatis indigotica extracts on pseudorabies
virus. J Ethnopharmacol. 2009 May 4;123(1):61-7. Epub 2009 Mar 4.
• Chen C, et al. Zhongyao Yaolixue, 2nd Edition. Shanghai Science and Technology Publishing, 2015; 88-90.
• Yang Z, et al. Antiviral activity of Isatis indigotica root-derived clemastanin B against human and avian influenza A
and B viruses in vitro. Int J Mol Med. 2013 Apr;31(4):867-73.
• Wang XL, et al. Chemical consitituents from root of Isatis indigotica. Zhongguo Zhong Yao Za Zhi. 2013
• Apr;38(8):1172-82. •

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715


Tel: 626-780-7182 • Fax: 626-363-9751 • Website: www.eLotus.org • Email: info@eLotus.org
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine. 8
Da Qing Ye (Folium Isatidis) Da Qing Ye (Folium Isatidis)

• Antibacterial • Antiviral: Da Qing Ye has antiviral effect


• Antiviral against influenza A virus, Japanese
• Antitoxin encephalitis virus, adenovirus, herpes
• Anti inflammatory
Anti-inflammatory simplex virus 1 and 2,
2 hepatitis B virus and
coxsackie virus.
• Chen C, et al. Zhongyao Yaolixue, 2nd Edition. Shanghai Science and Technology Publishing, 2015; 88-90.

• •

Yu Xing Cao (Herba Houttuyniae) Yu Xing Cao (Herba Houttuyniae)

• Clears heat, • Antibacterial


eliminates toxins and • Antiviral
drains pus • Anti-inflammatory
• Promotes normal
urination

• •

香椿葉 Xiang Chun Ye


Yu Xing Cao (Herba Houttuyniae) (Folium Toonae Sinensis)
• Antiviral and virucidal: Yu Xing Cao has • Xiang Chun Ye clears
antiviral effect against numerous types of heat and eliminates
viruses: herpes simplex virus (HSV), acyclovir- toxins to treat Lung
resistant HSV, coronavirus in severe acute heat with cough.
respiratory syndrome (SARS), H1N1 influenza • It also clears heat and
virus, pseudorabies herpes, influenza virus, and eliminates toxins from
human immunodeficiency virus. the skin to treat sores
• Chiang LC, et al. Anti-Herpes simplex virus activity of Bidens pilosa and Houttuynia cordata. Am J Chin Med.


2003;31(3):355-62.
Lau KM, et al. Immunomodulatory and anti-SARS activities of Houttuynia cordata.J Ethnopharmacol. 2008 Jun
and abscesses.
19;118(1):79-85. doi: 10.1016/j.jep.2008.03.018. Epub 2008 Mar 30.
• Chou SC, et al. The constituents and their bioactivities of Houttuynia cordata. Chem Pharm Bull (Tokyo). 2009
Nov;57(11):1227-30.
•• Ren X, et al. The effect of Houttuynia cordata injection on pseudorabies herpesvirus (PrV) infection in vitro. Pharm •
Biol. 2011 Feb;49(2):161-6.
• Hayashi K, et al. Virucidal effects of the steam distillate from Houttuynia cordata and its components on HSV-1,
influenza virus, and HIV. Planta Med. 1995 Jun;61(3):237-41.

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715


Tel: 626-780-7182 • Fax: 626-363-9751 • Website: www.eLotus.org • Email: info@eLotus.org
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine. 9
Xiang Chun Ye (Folium Toonae Sinensis) Shi Gao (Gypsum Fibrosum)

• Antiviral: Xiang Chun Ye exerts antiviral effect • Clears heat, sedates


by inhibiting the replication of coronavirus to treat fire, relieves irritability
severe acute respiratory syndrome (SARS), a and quenches thirst
life-threatening disease. • Clears Lung heat
• Xiang Chun Ye is the most effective herb of all • Clears heat in the
tested from Shang Han Lun (Discussion of Cold- Stomach and
Induced Disorders) and Wen Bing Tiao Bian Stomach channel
(Systematic Differentiation of Warm Disease).
• Chen CJ, et al. Toona sinensis Roem tender leaf extract inhibits SARS coronavirus replication. J Ethnopharmacol.
2008 Oct 30;120(1):108-11.

• •

Shi Gao (Gypsum Fibrosum)


Zhi Mu (Rhizoma Anemarrhenae)
Shi Gao (Gypsum Fibrosum) Max Effect

• Antipyretic: Shi Gao has an antipyretic action to


lower body temperature. The antipyretic function
of Shi Gao has a rapid onset, but only short
duration of action.
• Zhi Mu (Rhizoma Anemarrhenae), in
Min Effect

comparison, has slower onset of action but much


longer duration. Therefore, these two herbs are
synergistic in action and are commonly
combined.

Time 4 hrs 8 hrs

Zhi Zi (Fructus Gardeniae) Zhi Zi (Fructus Gardeniae)

• Sedates fire and • Antibacterial • Antihypertensive


relieves irritability • Antiviral • Hepatoprotective
• Clears heat and drains • Antifungal • Antifibrotic
dampness downwards • Anti inflammatory
Anti-inflammatory • Cholagogic
• Clears heat, cools • Pancreas protective
blood and stops
bleeding • Gastroprotective
• Reduces swelling and • Neuroprotective
relieves pain • Radioprotective
• •

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715


Tel: 626-780-7182 • Fax: 626-363-9751 • Website: www.eLotus.org • Email: info@eLotus.org
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine. 10
Zhi Zi (Fructus Gardeniae)

• Anti-inflammatory: Zhi Zi (Fructus • 2019 Novel Coronavirus -


Gardeniae) contains geniposide, which has Important Information for Clinicians
marked effect to reduce inflammation and – Carlos del Rio, MD; Preeti N. Malani, MD. JAMA. Published online
February 5, 2020. doi:10.1001/jama.2020.1490
protect against acute lung injury induced
by lipopolysaccharide.

• Xiaofeng Y, et al. Geniposide, an iridoid glucoside derived from Gardenia jasminoides, protects
Carlos del Rio, MD; Preeti N. Malani, MD. JAMA. Published online February 5, 2020. doi:10.1001/jama.2020.1490
against lipopolysaccharide-induced acute lung injury in mice. Planta Med. 2012 Apr;78(6):557-64.

• As of February 4, 2020: • The innate immune system is the first line of defense
– more than 20 000 cases of 2019-nCoV reported against pathogens. Cells in that system respond
– more than 400 deaths immediately to foreign invaders. (The adaptive
– 98.9% of them in China
immune system, by contrast, learns to recognize
specific
ifi pathogens,
th b
butt ttakes
k llonger tto join
j i th
the
– median age of patients is between 49 and 56 years
battle.)
– very rare in children (2 cases only)
• The innate immune response is stronger in children
exposed to 2019 nCoV, as they fight off infection
more readily than adults, suffering only mild
symptoms.
Carlos del Rio, MD; Preeti N. Malani, MD. JAMA. Published online February 5, 2020. doi:10.1001/jama.2020.1490 Carlos del Rio, MD; Preeti N. Malani, MD. JAMA. Published online February 5, 2020. doi:10.1001/jama.2020.1490

Herbs with Immunostimulant Effect Yu Ping Feng San (Jade Windscreen Powder)

• Ba Ji Tian (Radix Morindae Officinalis), Bai Bian Dou (Semen Lablab Album), Bai Shao (Radix
Paeoniae Alba), Ban Lan Gen (Radix Isatidis), Bie Jia (Carapax Trionycis), Chan Su (Venenum • Huang Qi (Radix Astragali)
Bufonis), Ci Wu Jia (Radix et Rhizoma seu Caulis Acanthopanacis Senticosi) , Da Suan (Bulbus Allii
Sativi), Dang Gui (Radix Angelicae Sinensis), Dang Shen (Radix Codonopsis), Dong Chong Xia Cao
(Cordyceps), Du Zhong (Cortex Eucommiae), E Jiao (Colla Corii Asini), Fang Feng (Radix
• Bai Zhu (Rhizoma Atractylodis Macrocephalae)
Saposhnikoviae), Fu Ling (Poria), Fu Zi (Radix Aconiti Lateralis Praeparata), Gan Cao (Radix et
Rhizoma Glycyrrhizae), Ge Jie (Gecko), Ge Qiao (Concha Meretricis seu Cyclinae), Gou Qi Zi (Fructus • Fang Feng (Radix Saposhnikoviae)
Lycii), Gui Ban (Plastrum Testudinis), Hai Shen (Strichopus Japonicus), He Shou Wu (Radix Polygoni
Multiflori), Huang Jing (Rhizoma Polygonati), Huang Lian (Rhizoma Coptidis), Huang Qi (Radix
Astragali), Jiao Gu Lan (Rhizoma seu Herba Gynostemmatis), Jin Yin Hua (Flos Lonicerae Japonicae),
Ling Zhi (Ganoderma), Long Dan (Radix et Rhizoma Gentianae), Long Yan Rou (Arillus Longan), Lu
Xian Cao (Herba Pyrolae), Mai Dong (Radix Ophiopogonis), Nu Zhen Zi (Fructus Ligustri Lucidi), Pu
Gong Ying (Herba Taraxaci), Qing Mu Xiang (Radix Aristolochiae), Ren Shen (Radix et Rhizoma
Ginseng), San Qi (Radix et Rhizoma Notoginseng), Sang Shen (Fructus Mori), Sha Yuan Zi (Semen
Astragali Complanati), Shan Yao (Rhizoma Dioscoreae), Shan Zha (Fructus Crataegi), She Xiang
(Moschus), Shi Gao (Gypsum Fibrosum), Suan Zao Ren (Semen Ziziphi Spinosae), Suo Yang (Herba
Cynomorii), Tian Ma (Rhizoma Gastrodiae), Tu Si Zi (Semen Cuscutae), Wu Mei (Fructus Mume), Xian
Mao (Rhizoma Curculiginis), Xiang Ru (Herba Moslae), Yin Yang Huo (Folium Epimedii), Yu Xing Cao
(Herba Houttuyniae), Zhu Ling (Polyporus) and Zi He Che (Placenta Hominis).

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715


Tel: 626-780-7182 • Fax: 626-363-9751 • Website: www.eLotus.org • Email: info@eLotus.org
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine. 11
Yu Ping Feng San (Jade Windscreen Powder)

• Wei (defensive) qi deficiency: spontaneous


sweating, aversion to wind and cold, increased
susceptibility to invasion of exterior pathogens,
pale face, pale tongue, white tongue coating, and
a floating, deficient pulse.
• Prevention of respiratory tract infection, allergic
rhinitis, abnormal perspiration, nephritis, and
facial paralysis.

清肺排毒汤 Qing Fei Pai Du Tang 清肺排毒汤 Qing Fei Pai Du Tang
(Clear the Lung and Eliminate Toxins Decoction) (Clear the Lung and Eliminate Toxins Decoction)
• Ma Huang (Herba Ephedrae), 9g • Jiang Ban Xia (Rhizoma Pinelliae Praeparatum
• Zhi Gan Cao (Radix et Rhizoma Glycyrrhizae cum Zingibere et Alumine), 9g • Drink the warm decoction twice daily 40
Praeparata cum Melle), 6g • Sheng Jiang (Rhizoma Zingiberis Recens), 9g minutes after meals. Folllow with half to
• Ku Xing Ren (Semen Armeniacae Amarum), 9g • Zi Wan (Radix et Rhizoma Asteris), 9g
• Shi Gao (Gypsum Fibrosum), 15-30g (pre-decoct) • Kuan Dong Hua (Flos Farfarae), 9g one bowl of rice porridage.
• Gui Zhi (Ramulus Cinnamomi), 9g • She Gan (Rhizoma Belamcandae), 9g
• Ze Xie (Rhizoma Alismatis), 9g • Xi Xin (Radix et Rhizoma Asari), 6g • Dosage
D off Shi Gao
G (Gypsum
(G Fibrosum)
Fib )


Zhu Ling (Polyporus), 9g
Bai Zhu (Rhizoma Atractylodis Macrocephalae), 9g


Shan Yao (Rhizoma Dioscoreae), 12g
Zhi Shi (Fructus Aurantii Immaturus), 6g
should be adjusted based on severity of
• Fu Ling (Poria), 15g • Chen Pi (Pericarpium Citri Reticulatae), 6g fever.
• Chai Hu (Radix Bupleuri), 16g • Guang Huo Xiang (Herba Pogostemonis), 9g
• Huang Qin (Radix Scutellariae), 6g


国家中医药管理局; https://mp.weixin.qq.com/s/0U9tAMdfQfrWZz_43Bc0bg 国家中医药管理局; https://mp.weixin.qq.com/s/0U9tAMdfQfrWZz_43Bc0bg

吴有性 Wū Yŏu-Xìng, 1580’s-1660’s

• With Wuhan on Lockdown for More


Than 10 days, the Chinese Government
Announces a Major Change in Strategy:
All Patients with Confirmed Infections
to take Chinese medicine.


心德园 https://mp.weixin.qq.com/s/hY--Q0-lotoWM44Not5DvA

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715


Tel: 626-780-7182 • Fax: 626-363-9751 • Website: www.eLotus.org • Email: info@eLotus.org
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine. 12
References References

• https://www.who.int/emergencies/diseases/novel- • https://www.nejm.org/doi/full/10.1056/NEJMoa20
coronavirus-2019 01017
• https://www.cdc.gov/coronavirus/2019- • https://jamanetwork.com/journals/jama/pages/cor
ncov/about/index.html onavirus alert
onavirus-alert
• https://www.fda.gov/emergency-preparedness- • https://www.thelancet.com/journals/lancet/article/
and-response/mcm-issues/novel-coronavirus- PIIS0140-6736(20)30305-6/fulltext
2019-ncov
• https://www.nih.gov/health-
information/coronavirus

Single/Individual Herbs Herbal Formulas

Clinical Manual of Oriental Medicine

Lotus Institute of Integrative Medicine, PO Box 92493, City of Industry, CA 91715


Tel: 626-780-7182 • Fax: 626-363-9751 • Website: www.eLotus.org • Email: info@eLotus.org
Shall not be copied, duplicated, or distributed in any format or be used for teaching without prior written consent from Lotus Institute of Integrative Medicine. 13
Evergreen Herbs is not just an Herbal company, we are an
environmentally friendly, health conscious contributor to the health-
care community at large. Evergreen was founded by Dr. John Chen
and Tina Chen, siblings and coauthors of the Chinese Medical
Herbology and Pharmacology, and the Chinese Herbal Formulas
and Applications books.
Evergreen is a family business that is run by professionals like you
who care about Chinese medicine. And as a family business, we
have the well-being and satisfaction of our customers at the top
of our list. We care about the quality of our herbs, because we
care about our consumers, and have your best interest at heart.
Our goal is to support you in improving your clinical skills, and
enhancing the well-being of your patients.
To learn more about Evergreen Herbs and our products, please

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