MDCAT BIOLOGY MCQS BY HAMZULLAH KHAN LECTURER BIOLOGY GOVT

GEGREE COLLEGE LIAQUAT PUR

1. Which one is correct base pairing for DNA molecule?
A) Cytosine - Uracil C) Adenine – Thymine
B) Thymine - Guanine D) Thymine - Uracil
2. In one strand of DNA, the base sequence is CAT GAC TAG. What is the base
sequence on the other strand?
A) CAT TAG GAC C) TAC ACT OCT
B) GAT GTC ACT D) GTA CTG ATC
3. Sugar present in DNA is
A) Heptose C) Tetrose
B) Hexose D) Pentose
4. Which three codons are nonsense codons?
A) UAA, UAU, UUA C) UGA, UAG, UAA
B) UGG,UGA,UAU D) UGG,UAA,UAG
5. Methionine is specified by
A) Stop codon C) AUG
B) Start codon D) Both B and C
6. In mitochondria UGA specifies as:
A) Stop codon C) Tryptophan
B) Initiation codon D) Methionine
7. Three nucleotide sequence on tRNA that specifies an amino acid is
A) Codon C) Anticodon
B) Nonsense codon D) Genetic code
8. Initiation complex in translation is composed of
A) Ribosome and aminoacyl-tRNA C) Ribosome and tRNA
B) tRNA and aminoacyl-tRNA D) None of these
9. Strand of DNA which is not transcribed is called
A) Antisense C) Template
B) Coding D) None of these
10. Which of the following can kill mice if injected separately?
A) Live R type pneumococcus C) Heat killed R type pneumococcus
B) Live S type pneumococcus D) Heat killed S type pneumococcus
11. X-Ray diffraction pattern of DNA was prepared by
A) Rosalind Franklin C) Maurice Wilkins
B) Watson D) Crick
12. Which ones are pyrimidines:
A) Cytosine, thymine and Adenine C) Cytosine, Guanine and thymine
B) Adenine, Guanine and Cytosine D) Cytosine, Thymine and Uracil
13. Ribose is a
A) Hexose sugar C) Tetrose sugar
B) Pentose sugar D) Triose sugar
14. Nitrogen bases of nucleotides in RNA are attached
A) Sugar molecules C) One another
B) Phosphate radicals D) All A,B,C
15. Adenine is
A) Purine C) Nucleoside
B) Pyrimidine D) Nucleotide
16. Which one is found only in RNA?
A) Cytosine C) Uracil
B) Adenine D) Guanine
17. In a typical nucleotide, phosphoric acid is attached to pentose sugar at carbon
number:
a) 1 b) 2 c) 3 d) 5
18. Identify the structure:

a) Guanine b) Thymine c) Uracil d) Cytosine

19. Which of the following nucleotide is not found in DNA?
a) d-AMP b) d-UMP c) d-GMP d) d-CMP
20. Link formed between nitrogenous base and pentose sugar is:
a) C-C link b) C-N Link c) C-O link d) C-O-P
link
21. Which of the following dose not Erwin Chargaff rule?
a) Purines = Pyrimidine b) Adenine + Thymine = Guanine+ Cytosine
c) Adenine= Thymine d) Adenine +Guanine= Thymine+ Cytosine
22. X-Ray diffraction analysis of DNA was first carried out by:
a) Fredrick Miescher b) Maurice Wilkins c) Rosalind Franklin
d) James Watson
23. Diameter of DNA double helix is about:
a) 3.4 nm b) 34 nm c) 2.0 nm d) 34 pm
24. Which of the following correctly represent sites for synthesis and functioning of RNAs
in a eukaryotic cell?
SYNTHESIS FUNCTION
a) Nucleus Nucleus
b) Cytoplasm Cytoplasm
c) Nucleus Cytoplasm
d) Cytoplasm Nucleus

1. Mammalian Kidney can conserve water by reabsorption of glomerular filtrate by over

a. 88.5% b. 86.5% c. 99.5% d. 98.5%
2. High degree of renal failure is also called
a. Uremia b. Leukemia c. Anemia d. Lithotripsy
3. Which one is least toxic among the followings
a. Urea b. Uric acid c. Ammonia d. Both a and b
4. Antidiuretic hormone (ADH) is also called
a. Oxytocin b. ACTH c. Vasopressin d. Prolactin
5. Lack of vasopressin hormone causes
a. diabetes mellitus b. diabetes insipidus c. Parkinson’s disease d. Addison’s
disease
6. The animals that generate their own body heat through heat production as by product
during metabolism are called
a. Endotherm b. Ecototherm c. Heterotherm d. All
7. Incidence of uric acid stone is
a. 5% b. 10% c. 15% d. 70%
8. Most land mammals respond to cold by raising their
a. Tail b. Head c. Legs d. Furs
9. Aldosterone plays role in
a. Transport of water b. Uptake of sodium in loop of Henle
c. Transport of K+ ion into kidney d. Reabsorption of water
10. Non-surgical removal of kidney stone is called
a. dialysis b. kidney transplant c. uremia d. Lithotripsy
Excretion In Man
11. Water reabsorption through glomerular filtrate is regulated by
(a) calcitonin (b) adrenaline (c) aldosterone (d) ADH
12. Ureters of both the kidneys rain into:
(a) Urethra (b) urinary bladder (c) Pelvis (d) None of these
13. All the collecting tubules of human kidney finally discharged into the;
(a) Hilus (b) ureter (c) pelvis (d) urinary bladder
14. The increase water supply to the human body results in decrease secretion of the
hormone;
(a) Glucagons (b) oxytocin (c) anti diuretic (d) insulin
15. The useful substances of glomerular filtrate are reabsorbed in the:
(a) proximal tubule (b) distal tubule (c) loop of Henle (d) collecting duct
16. The central cavity of the kidney is known as the:
(a) hilus (b) pelvis (c) cortex (d) medulla
17. The arterioles that bring blood from renal artery to the Bowman's capsule are
(a) Afferent tubules (b) Efferent tubules (c) Peritrbular capillaries (d) Vasa recta
18. The glomerular filtrate contains
(a) Glucose (b) Amino acids (c) Salts (d) All of these
19. The reabsorption of water in collecting tubules is under control of
(a) Aldosterone (b) ADH (c) Tubular secretion (d) Pressure filtration
Kidney Problems
20. About 70% of all stone types formed in kidney are
(a) Calcium phosphate type (b) Calcium oxalate type
 (c) Uric acid type (d) Both A&B
21. Incidence of calcium phosphate stone is
(a) 20% (b) 10% (c) 15% (d) 25%
22. One of the followings is practices to remove nitrogenous wastes in patients suffering
from chronic renal failure
(a) Iithotripsy (b) Dialysis (c) Uremia (d) Pyrexia

Dialysis
23. The high degree of renal failure is called
(a) oedema (b) uremia (c) hyperoxaluria (d)
hypercalcemia
24. The human abdominal cavity is lined by
(a) visceral mesoderm (b) endoderm (c) peritoneum (d) epidermis
25. The permanent treatment of uremia is
(a) Endless dialysis (b) Lithotripsy (c) Kidney transplant (d)
Haemodialysis
26. The part of kidney through which renal artery, vein and ureter pass into kidney
a. renal pelvis b. Hillum c. Hillus d. Medulla
27. The space between renal pyramids is called
a. renal space b. Pyramidal interstitium c. Renal column d. Renal pelvis
28. Which has more blood supply
a. Kidneys b. Liver c. Spleen d. Heart
29. Secretion of which ion occurs in collecting duct
a. H+ b. K c. Na+ d. Cl-
30. Which process is concerned with pH maintenance of urine and blood
a. Filtration b. Reabsorption c. Secretion d. All
31. The cells which are highly modified for filtration
a. podocytes b. Amoebocytes c) phagocytes d.
thrombocytes
32. Urea requires _____ amount of H2O as compared to NH3
a. 1/5th b. 1/10th c. 1/100th d. Equal
33. Where does the aldosterone act
a. Proximal tubule b. Distal tubule c. Ascending or thick limb d. Collecting
duct
34. All of which are possibly filtered except
a. Glucose b. Ions c. Proteins d. Amino acids
35. Reabsorption of water takes place in all segments except
a. Proximal convoluted tubule b. Distal convoluted tubule
c. Thick limb of loop of Henle d. descending loop of Henle
36. Which type of kidney stones formation is 15% in occurrence
a. Ca oxalates b. Ca phosphate c. Uric acid d. Cholesterol
37. Which is not true for dialysis
a. It is for cleaning the blood b. It is used for temporary management
 c. Hypertonic fluid is used in it d. Dialysis needs to be repeated
38. Most of the homeostasis is maintained by means of
a. Positive feedback b. Negative feedback
c. Precursor activation d. None
39. The pH of human urine is
a. 4-4.1 b. 4.2-4.5 c. 6-7 d. 4.5-8.5
40. Anti-diuretic hormones act on
a. Descending loop b. distal tubule
c. Collecting tubule of vertebrate nephron d. Both b and c
41. This results in decrease in plasma level of urea
a. renal failure b. Uremia c. Dialysis d. None
42. Which dialysis needs to be repeated more frequently?
a. Hemodialysis b. peritoneal dialysis c. Both dialysis d. Artificial
dialysis
43. In glomerulus blood arrives through
a. Efferent b. afferent arteriole c. peritubular Capillaries d.
None
44. Nephrons with loop of Henle and glomeruli in outer cortex are
a. Juxtamedullary b. cortical c. Medullary d. Both a and
b
45. 7/8 of all nephrons are
a. cortical b. medullary dc. Juxtamedullary d. None
46. Which acts as semi permeable membrane during peritoneal dialysis
a. Pleura b. Wall of gut c. Both a and b d. Blood vessels
47. Erythropoietin helps in
a. Heat production b. R.B.C. Production c. Growth d. W.B.C. formation
+
48. If blood is acidic H are
a. reabsorbed b. secreted c. taken through intravenous injections d.
All
49. Which one of the following is missing in female
a. urethra and ureter b. prostate gland and inner sphincter
muscle
c. Prostate gland and spongy urethrad. spongy urethra and external sphincter muscle
50. Which one of the following is under the voluntary control
a. internal sphincter muscle b. external sphincter muscle
c. prostate gland d. Smooth muscles of urinary bladder