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ORIGINAL CONTRIBUTIONS

Baking soda as an abrasive in


toothpastes
Mechanism of action and safety and effectiveness
considerations

Anderson T. Hara, DDS, MSD, PhD; Cecilia P. Turssi, DDS, ABSTRACT


MSD, PhD
Background. Toothpastes can be formulated with
different abrasive systems, depending on their intended

T
he success of an oral hygiene regimen depends clinical application. This formulation potentially affects
primarily on its ability to properly remove food their effectiveness and safety and, therefore, requires
debris and biofilm formed on dental surfaces proper understanding. In this article, the authors focused
without disrupting the physical and chemical on abrasive aspects of toothpastes containing sodium bi-
integrity of these surfaces. Many factors contribute to carbonate (baking soda), which have gained considerable
achieving this goal, including brushing technique and attention because of their low abrasivity and good
behavior, as well as specific toothpaste-related aspects. compatibility, while providing clinical effectiveness
Toothpastes function as vehicles for active ingredients (further detailed in the other articles of this special issue).
with therapeutic and cosmetic functions and inactive The authors first appraised the role of toothpaste abrasivity
ones such as detergents, humectants, and flavors.1,2 on tooth wear, exploring some underlying processes and
Among therapeutic agents, fluoride is probably the most the existing methods to determine toothpaste abrasivity.
important, with strong evidence on dental caries and Types of Studies Reviewed. The authors reviewed
dental erosion prevention; fluoride not only shifts the the available data on the abrasivity of toothpastes con-
mineral equilibrium between the tooth and the sur- taining baking soda and reported a summary of findings
rounding environment toward the remineralization highlighting the clinical implications.
phase but also makes the tooth more resistant to Conclusions. On the basis of the collected evidence,
demineralization. Other relevant constituents include baking soda has an intrinsic low-abrasive nature because of
antimicrobials to inhibit biofilm growth, tartar control its comparatively lower hardness in relation to enamel and
compounds to inhibit calculus formation, and antisen- dentin. Baking soda toothpastes also may contain other
sitivity agents. Abrasive components are fundamental to ingredients, which can increase their stain removal effec-
removing dental surface stains, but they also improve tiveness and, consequently, abrasivity.
toothbrushing efficiency. Historically, abrasives in the Practical Implications. Even those formulations have
form of tooth powders or toothpastes have been used for abrasivity well within the safety limit regulatory agencies
dental cleaning purposes since ancient times. As previ- have established and, therefore, can be considered safe.
ously reported,1,3 ancient Egyptians scrubbed their teeth Key Words. Baking soda; toothpaste; enamel; dentin.
with a mixture of ox hoof ashes, burned eggshells, and JADA 2017:148(11 suppl):27S-33S
pumice; later, their medical Ebers Papyrus reported a http://dx.doi.org/10.1016/j.adaj.2017.09.007
toothpaste made of ground pebbles, honey, verdigris,
incense, and pulverized fruits. Ancient Greeks used a
mixture of burned shells, coral, talc, salt, and honey, and
ancient Romans used a blend of crushed bones and
Publication of this article was sponsored by Church & Dwight Co., Inc. oyster shells plus powdered charcoal and bark. More
The articles in this issue have an accompanying online continuing recently, in the 18th century, reports indicated that the
education activity available at http://www.ADA.org/bakingsoda. British included brick dust and crushed china in their
Copyright ª 2017 American Dental Association. All rights reserved. tooth powder.

JADA 148(11 suppl) http://jada.ada.org November 2017 27S


ORIGINAL CONTRIBUTIONS

Over time, the selection and incorporation of abra- however, are added in lower concentrations of 1% to 2%
sives in toothpastes have been optimized, and attention weight per weight, given their higher abrasivity in rela-
has been given to some specific abrasive systems. tion to enamel. In ideal circumstances, the toothpaste
However, despite the considerable historical back- formulation should be abrasive enough only to aid
ground, the large variety of toothpastes available with properly in the removal of dental plaque and stains from
different abrasive properties requires a proper under- dental surfaces.7 This makes baking soda a particularly
standing of their clinical applications, as well as of interesting option because it long has been regarded as 1
potential effectiveness and safety concerns. In particular, of the least, if not the least, abrasive material, allowing it
the use of sodium bicarbonate (baking soda) has to be added in much higher concentrations, often
attracted attention because it has relatively low abra- exceeding 50% weight per weight.
sivity. In this article, we review the effect of toothpaste
abrasivity on tooth wear, evidencing some mechanisms TOOTH WEAR AND TOOTHPASTE ABRASIVITY
of abrasive action; the existing evaluation methods used Wear can be defined as the progressive loss of material
to determine toothpaste abrasivity; and the literature on because of relative motion between surfaces and con-
the abrasive level of toothpastes containing baking soda, tacting substances. Four main types of wear are relevant
highlighting some of the clinical implications. to dental surfaces; namely, abrasive, corrosive (caused by
chemical agents), fatigue, and adhesive wear.8
DENTAL ABRASIVES AND TOOTHPASTE
FORMULATION
In abrasive wear, material is removed or displaced
from a surface by the action of hard particles either
From a safety standpoint, toothpaste abrasives often are moving between surfaces in relative movement or
investigated for the potential deleterious effects they embedded in 1 of the surfaces in relative movement.8-10
cause during toothbrushing. The ideal toothpaste should The latter arrangement describes 2-body abrasion,
have enough abrasiveness to remove surface stains exemplified by bruxism, also called dental attrition. The
properly without damaging the tooth. Therefore, exces- former mechanism describes 3-body wear, when particles
sively abrasive materials can abrade the tooth surface are interposed between the surfaces. Examples are wear
away, resulting in undesirable tooth wear. Many factors resulting from toothbrushing and mastication. Corrosive
define the degree of abrasivity of a given compound, wear occurs in situations in which the environment
including its hydration level; the size, hardness, shape, surrounding a sliding surface interacts chemically with it
and concentration of its particles; source; purity; and and reaction products are worn off from the surface.8-10
how it has been treated physically and chemically.1 In the oral cavity, corrosion best describes dental erosion
Some clinical factors modulate the effect of these abra- or erosive tooth wear, which results from the tooth’s
sives on the tooth surface, such as toothbrush stiffness, exposure to nonbacterial acids of intrinsic or extrinsic
toothbrushing pressure and frequency,4 and enamel origin. Fatigue wear occurs by means of intermittent
and dentin mineralization level. Some of the dental loading, resulting in repeated stressing and unstressing,
abrasives currently used include hydrated silica, hydrated which in time may lead to the formation and eventual
alumina, calcium carbonate, dicalcium phosphate dihy- break off of microcracks at or below the surface.8-10 Fa-
drate, calcium pyrophosphate, sodium metaphosphate, tigue has been the primary mechanism behind dental
perlite, nanohydroxyapatite, diamond powder, and abfraction lesions. Adhesive wear refers to the process in
baking soda.2 which 2 surfaces contact each other under load, leading
Ideally, abrasives should not interact chemically with to the local welding at the tips of the major asperities of
the active ingredients in the toothpaste. For instance, the surfaces.8,9 This type of wear has been related to
a calcium carbonate–based toothpaste should not be thread disengagement, screw loosening, and preload
formulated in conjunction with sodium fluoride because reduction in dental implant systems.11
chemical binding may occur between the 2 components Dental abrasive wear is of particular importance
reducing the amount of available fluoride.2 In that case, a because it may result from toothbrushing, the main
more chemically stable fluoride compound such as so- intervention universally performed to remove dental
dium monofluorophosphate is preferable. From this plaque and control caries and periodontal disease.4
perspective, hydrated silica abrasive and baking soda Toothbrushing abrasion may be an issue for dentin
systems are advantageous because they are compatible surfaces,12 more than for sound enamel,12-14 because the
with most active ingredients.2,5,6 latter is harder than almost all abrasives in toothpastes
Because of the different properties of each of these
abrasives and the intended clinical application of the
toothpaste, the amount added in each formulation var- ABBREVIATION KEY. ISO: International Organization for
ies.2 For instance, the most common abrasives, hydrated Standardization. NA: Not available. RDA: Radioactive (or
silica and calcium carbonate, may be used in the range relative) dentin abrasivity. REA: Radioactive (or relative)
of 8% to 20% weight per weight; alumina and perlite, enamel abrasivity.

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ORIGINAL CONTRIBUTIONS

(except the rarely used hydrated alumina, perlite, and wear also depends on the type of abrasive used in the
diamond powder).15 Simulation studies on lifetime toothpaste formulation.
enamel toothbrushing wear showed it to be minimal or At least when hydrated silica is used, the content of
clinically irrelevant, even if one considers enamel at its the abrasives plays a role in the tissue loss of softened
thinnest anatomic area (near the cervical area).16,17 enamel.18 However, contrary to expectations, the amount
Conversely, dentin can wear approximately 10 times of hydrated silica added to a toothpaste has a nonlinear
more than enamel over a 10-year period.4 However, one association with abrasiveness.18 Absence or high con-
should bear in mind that toothbrushing wear on acid- centrations of hydrated silica particles produced less
softened enamel can be 4-fold higher compared with that tissue loss than did formulations containing approxi-
on the sound surface.14 This holds true for eroded dentin mately 15% of such abrasives. These results may be
as well,18,19 which may show abrasion to be 4 to 5 times because in high concentration, abrasive particles tend to
higher than that observed in sound dentin, depending on agglomerate, preventing their rolling and therefore
the toothbrush stiffness.19 causing less abrasion. Investigators have found such
Toothbrushing is considered a major contributor to nonproportional association between particle content
dental abrasion and involves both 2-body and 3-body and abrasivity in a study with results showing that
abrasive wear processes20 because of the frictional forces increasing the level of particle concentration had only a
caused by abrasive particles. In 2-body abrasion, abrasive minor effect on the friction coefficient when brushing
particles constitute an integral part of 1 surface that slides was performed in the presence of diamond particles.20
against the other. This sliding takes place during tooth- Besides the abrasivity of a toothpaste, wear of dental
brushing because part of the abrasive particles of the hard tissues may be influenced by the pressure,14 dura-
toothpaste are trapped under the toothbrush filament tion, and frequency of brushing,15 as well as toothbrush
tips and scratch the surface.20 In 3-body abrasion wear, characteristics.4 Laboratory simulations showed a trend
abrasive particles are interposed between 2 surfaces in toward increasing dental wear with increased brushing
contact but are free to roll as well as to slide. Conse- pressure.28 Increasing of filament loading likely increases
quently, abrasive particles in the toothpaste constitute the load transmitted to the particles trapped between the
the third party interposed between the toothbrush and filament tips and dental surfaces.20 However, although
the tooth surface.8 Three-body abrasion accounts for the there is evidence that brushing load influences abrasion
main abrasion process during toothbrushing.21 of acid-softened enamel, investigators have speculated
Evidence indicates that toothbrushing abrasion is that it might be of minor importance for sound enamel.14
primarily a function of the abrasive level of the tooth- Results of simulations in our laboratory (Sabrah and
paste.4 Essentially, the degree of abrasiveness of a given colleagues, unpublished data, September 2013) have
compound depends on its hardness, shape, size, and shown that, depending on the toothpaste abrasivity,
concentration.2 However, the dental wear magnitude tooth wear may be maintained or increased because of
may vary according to the pressure, duration, and fre- brushing duration. When a low-abrasive toothpaste is
quency of brushing, as well as to the toothbrush bristle used, increasing brushing duration does not play a role in
stiffness and tip geometry of the filaments. the volume loss of teeth. In contrast, for high-abrasive
Despite the functional importance of abrasives, there toothpaste, tooth wear increases exponentially with the
are few reports in which the investigators have compared duration of brushing.
the various abrasives that may be contained in tooth- Although there are equivocal findings on how
pastes. In such studies, calcium carbonate has shown toothbrush stiffness affects abrasion,27,29-32 its combina-
lower abrasivity than has hydrated silica,22,23 whereas tion with toothpaste abrasivity seems to be important.12
baking soda has been classified as an agent of low In another laboratory simulation (Binsaleh and col-
abrasivity.3,7 Because dentin is softer than enamel and leagues, unpublished data, November 2015), we observed
most toothpaste abrasives have hardness similar to or that toothbrush bristle stiffness seems irrelevant when
greater than that of dentin,3,7,24 the dentin usually wears brushing with low-abrasive toothpaste. In addition, the
in a higher proportion. choice of a soft, medium, or hard toothbrush is of lesser
Limited knowledge exists with regard to the influence relevance to enamel than to dentin abrasion.12 However,
of the abrasive particle size on tooth wear. Toothpastes one should bear in mind that filament stiffness is likely to
with larger particles cause higher abrasion rates than follow toothpaste abrasivity in terms of relevance in the
those with small ones, on both sound25 and eroded abrasion process, even for dentin substrates.12 In-
dentin26,27 although results from a 2016 article showed no vestigators have speculated that abrasion of dental hard
effect of the particle size on softened (demineralized) tissues may be minimized if filaments are round ended
enamel abrasive wear.18 Investigators have hypothesized and smooth.33,34 In a laboratory simulation, however,
that there exists a threshold above which the wear rate flat-ended filaments entrain and trap fewer particles at
changes in different ways (that is, increases at lower the filament tip region than do filaments with rounded
rates, becomes constant, or decreases), but it is likely that tips,35 which might imply increased wear with the latter.

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ORIGINAL CONTRIBUTIONS

TABLE underestimated. Highly abrasive toothpastes can accel-


RDA* of different commercial erate the progression rate of dental abrasion,36 especially
in the cervical area, where dentin root surfaces may be
toothpastes, baking soda exposed owing to trauma or periodontal disease.
concentration, and stain removal. Therefore, there is great interest from clinicians and
TOOTHPASTE BAKING RDA IN VITRO especially oral care product manufacturers in testing the
SODA STAIN abrasive levels of toothpastes. Although clinical evalua-
(%) REMOVAL† tion of all the commercially available toothpastes is not
Pure Baking Soda (Arm & Hammer) 100 7‡ NA§ feasible, laboratory tests may provide a good indication

PeroxiCare (Arm & Hammer) 50-65 35 NA of their abrasive potential in relation to enamel and
Optic White (Colgate) 0 46¶ NA dentin. A radiation-based method developed more than
Fresh Mint (Sensodyne) 0 52# NA 50 years ago37,38 and known as radioactive (or relative)
Advance White Extreme Whitening 50-65 53# 64 dentin abrasivity (RDA) and radioactive (or relative)
Stain Defense (Arm & Hammer)
enamel abrasivity (REA) remains the standard test
Paradontax (GlaxoSmithKline; 67 56# NA adopted by the International Organization for Stan-
sold in Europe)
Sensitive Whitening With Tartar 35-45 57# 38
dardization ([ISO] standard 11609).39
Control (Arm & Hammer) Briefly, this test measures the abrasivity level of
Dental Care Advance Cleaning 50-65 60# NA dentifrices (RDA-REA value) in relation to a standard
(Arm & Hammer) abrasive material, which is given an arbitrary value of 100
Advance White Brilliant Sparkle 15-20 84¶ NA for RDA or 10 for REA. To obtain comparable RDA-REA
(Arm & Hammer)
data from different dentifrices, this test relies on the use
Regular (Colgate) 0 98# NA of a specific reference material (a specially manufactured
Baking Soda & Peroxide (Crest) NA 101# NA lot of either calcium pyrophosphate or hydrated silica
Truly Radiant Rejuvenating NA 118¶ 116 materials) described in ISO 11609. The test simulates
(Arm & Hammer)
toothbrushing conditions by brushing dental specimens
Extra Whitening (Sensodyne) 0 120# NA
created from extracted human teeth (root dentin for
Truly Radiant Clean & Fresh 10-20 132# 140
(Arm & Hammer) RDA and enamel for REA), previously irradiated with a
Truly Radiant Bright & Strong 35-45 134# 100 neutron flux sufficient to produce approximately 1
(Arm & Hammer) millicurie of phosphorus 32 beta radiation, in an auto-
Baking Soda & Peroxide (Colgate) NA 161# NA mated toothbrushing machine. Slurries of test tooth-
Antiplaque & Whitening NA 164# NA pastes or dental abrasives are prepared to mimic their
(Tom’s of Maine) mixture ratio with saliva in the mouth and are used for
Total Advanced Whitening (Colgate) 0 181# NA the brushing procedure. Depending on the abrasivity
3D White Luxe Diamond Strong 0 205# NA of the test toothpaste, more or less irradiated dental
(Crest)
substrate is abraded away from the tooth and released
Max Fresh With Whitening (Colgate) 0 205# NA
into the test slurry. The radiation level of the slurry is
3D White (Crest) 0 233¶ NA
measured with a standard method such as a scintillation
Pro Health Advanced Whitening 0 245# NA
Power (Crest)
counter and is used to calculate the abrasivity of the
* RDA: Radioactive (or relative) dentin abrasivity.
toothpaste, in relation to the standard abrasive material,
† Ratio of enamel stain removal of the toothpaste in relation to calcium tested in the exact same conditions.
pyrophosphate standard material.48 Data provided by Church & The RDA-REA tests were developed with the aim of
Dwight Co., Inc.
‡ Source: Barnes.24 reducing and controlling for the variables and relevant
§ NA: Not available. behavioral, chemical, mechanical, and biological aspects,
¶ RDA test performed in an independent laboratory (study 14-267,
August 2014).
which invariably limits its clinical application.37 As an
# RDA test performed in an independent laboratory (study 17-205, example, brushing dental surfaces for 1,500 to 2,000
June 2017). strokes continuously, as recommended by the ISO
standard guideline to allow for proper sensitivity of the
test, has limited clinical application. Similarly, the lack of
TOOTHPASTE ABRASIVITY EVALUATION METHODS saliva in the testing system affects the characteristics of
From the clinical perspective, the importance of dental the slurry, most importantly its acidity and viscosity
wear diseases has increased considerably, especially with control40; in addition, the absence of acquired pellicle on
the increase in lifespan and tooth retention rates. Because dental surfaces may play an important role.41 However,
teeth are kept for longer in the mouth, they become more the use of pooled fresh human saliva in this type of
susceptible to the development of dental wear. The laboratory study is not practical, and the use of artificial
abrasive level of toothpastes can affect this process and, saliva without all the components of natural saliva would
despite the lack of clinical data in this area, should not be have a substantially reduced effect. To address these and

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ORIGINAL CONTRIBUTIONS

other clinical aspects,


we recommend more
elaborate in vitro
and in situ models.
Although there are
several limitations that
might affect clinical
abrasive wear, RDA
can be considered a
useful tool for deter-
mining the relative
abrasive level of denti-
frices and abrasive
powders.42
The ISO 11609 also
describes an alternative
Figure. Photos of toothbrushing wear on cervical area with toothpastes of different abrasivity levels. Lower
method for assessing abrasivity: PeroxiCare (Arm & Hammer; radioactive [or relative] dentin abrasivity [RDA]: 35; 50%-65% baking soda).
abrasivity, which mea- Medium abrasivity: Truly Radiant Clean & Fresh (Arm & Hammer; RDA: 132; 10%-20% baking soda). Higher abra-
sures toothbrushing and sivity: Pro Health Advanced Whitening Power (Crest; RDA: 245; no baking soda). *After horizontal toothbrushing
laboratory simulation of 35,000 double brushing strokes at 200-gram loading.
toothpaste abrasive ef-
fects directly on the
dental substrate by means of profilometry. It has the and 40 (4  the reference material) for the RDA and
advantage of not using irradiated specimens, therefore REA values, respectively. Therefore, for safety reasons,
not requiring access to a research reactor and regulatory investigators must consider these limits.39
clearance for isotope use. Results of studies in which the
investigators compared the profilometry- and radiation- CLINICAL IMPLICATIONS
based methods43,44 have shown that these methods have The data provided in the table24 show that toothpastes
potential as alternatives, although further verification seems containing baking soda, even when associated with
to be needed. Because of its historical seniority and the cleaning and whitening claims, showed RDA ranging
large body of research data, the RDA radiotracer method between 35 and 134 (for those for which data were avail-
should take precedence over the profilometry-based able), which is well within the safety limit of 250 proposed
method when a discrepancy between them arises.36,45-47 by the ISO. Such RDA values may be ascribed to the fact
Given the limitations imposed by the laboratory that baking soda is 1 of the softest abrasives present in the
nature of the RDA-REA tests, one should use caution most toothpastes.3 The intrinsic hardness of baking soda
when extrapolating these results to the clinical situation. is of the same magnitude as that of dentin and is less than
The oral care industry and some researchers arbitrarily that of enamel or of other commonly used dentifrice
have proposed a rank based on the toothpaste RDA abrasives, such as calcium carbonate, anhydrous dical-
values, suggesting that a high-abrasive toothpaste would cium phosphate, and calcium pyrophosphate.24 Although
be in the range of approximately 151 to 250, a moderate- studies still are needed, baking soda toothpastes may be
abrasive toothpaste would be in the range of 70 to 150, appropriate for patients at high risk of developing dental
and a low-abrasive toothpaste would be below 70.36 erosion because these toothpastes have lower abrasive
Although this classification seems reasonable from a levels and can minimize abrasive wear on softened or
purely abrasive property perspective, there are myriad eroded dental surfaces. The same applies for exposed root
clinical factors that directly or indirectly can affect the surfaces with dentin hypersensitivity symptoms. Baking
clinical dental abrasive wear caused by the toothpaste. soda is a low-abrasive substance and appropriate for
Additional modulating factors should be considered, dental resin composites and acrylic resin denture teeth
such as the behavioral (frequency, pressure, length, and because their hardness values are equivalent to or higher
so on), chemical and physical (fluoride, detergents, pH, than that of dentin.
temperature, and so on), mechanical (abrasive, tooth- Another beneficial characteristic of baking soda is
brush), and biological (type and condition of the sub- its high solubility, which also accounts for its low abra-
strate, saliva, and dental pellicle), as well as any particular sivity.3 Such a low-abrasive nature coupled with the high
interaction among them.46 Therefore, clinical validation solubility explain the low RDA values for the pure baking
still is needed. Nonetheless, it is important to pay soda (Table),24 which one mistakenly could assume to be
attention to the fact that the ISO guideline previously more abrasive than toothpastes containing this ingre-
mentioned sets the upper acceptable abrasivity limit of dient at lower concentrations (10%-20%, 35%-45%, or
the toothpaste to be 250 (2.5  the reference material) 50%-65%), despite an inverse relationship that seems to

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ORIGINAL CONTRIBUTIONS

exist between baking soda content and toothpaste 1. Stookey GK. Toothpaste: what’s in it? Available at: http://www.
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brushed cervical area, similar to findings in the teeth Mechanical behavior and failure analysis of prosthetic retaining screws
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baking soda, flavorings, and sweeteners.24 Baking soda 16. Gaspersic D. Some principles in the dental crown construction in
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tration. The amounts of baking soda in toothpastes bear Investigation of erosion and abrasion on enamel and dentine: a model in
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no clinical concern related to toxicity.49 802-808.
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J Dent. 2016;54:62-67.
Baking soda is a safe toothpaste ingredient and has a low 19. Bizhang M, Riemer K, Arnold WH, Domin J, Zimmer S. Influence of
abrasive potential in relation to dental surfaces. The bristle stiffness of manual toothbrushes on eroded and sound human
addition of other abrasives to toothpastes containing dentin: an in vitro study. PLoS One. 2016;11(4):e0153250.
baking soda, mostly hydrated silica, seems to improve 20. Lewis R, Dwyer-Joyce RS. Interactions between toothbrush and
toothpaste particles during simulated abrasive cleaning. Proc Inst Mech Eng
the toothpastes’ cleaning effectiveness and abrasive Part J J Eng Tribol. 2006;220(8):755-765.
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tions are well within the safety limit defined by regula- treatment of dentine hypersensitivity. Monogr Oral Sci. 2013;23:75-87.
22. Camargo IM, Saiki M, Vasconcellos MB, Avila DM. Abrasiveness
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Dr. Hara is an associate professor, Department of Cariology, Operative 23. Moore C, Addy M. Wear of dentine in vitro by toothpaste abrasives and
Dentistry and Dental Public Health, Indiana University School of Dentistry, detergents alone and combined. J Clin Periodontol. 2005;32(12):1242-1246.
415 Lansing St., Indianapolis, IN, e-mail ahara@iu.edu. Address corre- 24. Barnes CM. An evidence-based review of sodium bicarbonate as a
spondence to Dr. Hara. dentifrice agent. Compend Contin Educ Oral Hyg. 1999;6(3):3-9.
Dr. Turssi is an assistant professor, Division of Cariology and Restorative 25. De Boer P, Duinkerke AS, Arends J. Influence of tooth paste particle
Dentistry, São Leopoldo Mandic Institute and Dental Research Center, size and tooth brush stiffness on dentine abrasion in vitro. Caries Res. 1985;
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American Dental Association. enamel: an in vitro study. Acta Odontol Scand. 2008;66(4):231-235.

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