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D.1. Leukocytosis can be caused by

A. increased movement of immature cells out of the bone marrow’s proliferative compartment
B. increased mobilization of granulocytes from the maturation-storage compartment
C. increased movement of granulocytes from the marginating pool to the circulating pool
D. all of the above
D. 2. Neutrophilia can be related to a variety of conditions or disorders. Select the appropriate condition/s.
A. Surgery
B. Burns
C. Stress
D. All of the above
D.3. Charcot-Leyden crystals can be found in _____ of patients with active eosinophilic inflammation.
A. sputum
B. tissues
C. stool
D. all of the above
D.4. Monocytosis can be observed in
A. tuberculosis
B. fever of unknown origin
C. rheumatoid arthritis
D. all of the above
D. 5. Neutropenia can be observed in
A. bone marrow injury
B. nutritional defi ciency
C. increased destruction and utilization
D. all of the above
Questions 6 through 9: Match the following abnormalities with the appropriate characteristic.
A. Gigantic peroxidase-positive deposits.
B. Precipitated mucopolysaccharides.
C. Döhle body–like inclusions.
D. Single or multiple pale-blue staining inclusions.

B.6. Alder-Reilly inclusions

A 7. Chédiak-Higashi syndrome
D.8. Döhle body inclusions
C.9. May-Hegglin anomaly

Questions 10 through 12: Match the following abnormalities with the appropriate characteristic.
A. Dark blue-black precipitates of RNA.
B. Five or more nuclear segments.
C. Failure of the nucleus to segment.
D. Precipitated mucopolysaccharides.
C.10. Pelger-Huët anomaly
A.11. Toxic granulation
B.12. Hypersegmentation

Questions 13 through 16: Match the following abnormalities with the appropriate condition.
A. Associated with a deficiency of vitamin B12 or folic acid
B. Associated with frequent infections in children or young adults
C. May be related to a maturational arrest in some acute infections
D. Associated with viral infections and burns
B.13.Chédiak-Higashi syndrome
D.14. Döhle bodies
C.15.Pelger-Huët anomaly
A.16.Hypersegmentation

Questions 17 through 21: Select the appropriate cell type involved in the following disorders.
A. Neutrophilic series
B. Monocytic-macrophage series
B. 17. Gaucher disease
B.18. Niemann-Pick disease
A. 19. Chédiak-Higashi syndrome
A. 20. Chronic granulomatous disease
A.21. Lazy leukocyte syndrome

D.22. In the United States, human diseases caused by Ehrlichia species can be caused by
A. E. chaffeensis
B. E. ewingii
C. E. phagocytophilia (similar or identical to)
D. all of the above
B. 23. Ehrlichiosis is transmitted by _____.
A. mosquitoes
B. ticks
C. rats
D. cats
D.24. Gaucher cells have
A. wrinkled cytoplasm
B. one to three nuclei
C. a deficiency of b-glucocerebrosidase
D. all of the above
C.25. Which of the following inherited leukocyte disorders might be seen in Hurler syndrome?
A. Pelger-Huët anomaly
B. Chédiak-Higashi disease
C. Alder- Reilly anomaly
D. May-Hegglin Anomaly
C.26. Individuals with X-linked SCID have a mutation that affects their ability to synthesize:
A. Deaminase
B. Oxidase c. IL-2 receptor
C. IL-2 Receptor
D. IL-8 Receptor
D.27. The neutrophils in chronic granulomatous disease are incapable of producing:
A. Hydrogen peroxide
B. Hypochlorite
C. Superoxide
D. All of the Above
A.28. Which of the following inherited leukocyte disorders is caused by a mutation in the lamin B receptor?
A. Pelger-Huët anomaly
B. Chédiak-Higashi disease c. Alder-Reilly anomaly
C. Alder-Reilly Anomaly
D. May-Hegglin Anomaly
B.29. The expected complete blood count (CBC) results for women in active labor would include:
A High total white blood cell (WBC) count with increased lymphocytes
B. High total WBC count with a slight shift to the left in neutrophils c. Normal WBC count with
increased eosinophils
C. Normal WBC count with increased eosinophil
D. Low WBC count with increased monocytes
B.30. Which of the following lysosomal storage diseases is characterized by macrophages with striated cytoplasm
and storage of glucocerebroside?
A. Sanfilippo syndrome
B. Gaucher disease
C. Fabry disease
D. Niemann-Pick disease