PHARMACEUTICAL AND ORGANIC

MEDICINAL CHEMISTRY

POSTLAB DISCUSSION
 EXPERIMENT #1

DETECTION OF COMMON ELEMENTS

DETECTION OF COMMON ELEMENTS

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR ACIDITY AND BASICITY

DETECTION OF COMMON ELEMENTS

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR HYDROGEN AND OXYGEN

DETECTION OF COMMON ELEMENTS

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR CARBON

DETECTION OF COMMON ELEMENTS

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR NITROGEN

DETECTION OF COMMON ELEMENTS
Solution with
chlorine

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR HALOGEN

DETECTION OF COMMON ELEMENTS

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR SULFUR

DETECTION OF COMMON ELEMENTS

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR PHOSPHORUS

DETECTION OF COMMON ELEMENTS
MILLON’S TEST

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR PHENYL OR BENZENE RING

DETECTION OF COMMON ELEMENTS
FERRIC CHLORIDE
TEST

SULFAMERAZINE

Chlorobutanol Barbital Sodium

TEST FOR PHENYL OR BENZENE RING

DETECTION OF COMMON ELEMENTS

SULFUR CONTAINING
DETECTION OF COMMON ELEMENTS

DEXAMETHASONE SODIUM
PHOSPHATE

DISOPYRAMIDE PHOSPAHTE

CLINDAMYCIN PHOSPHATE

PHOSPORUS CONTAINING
DETECTION OF COMMON ELEMENTS

HALOGEN CONTAINING
DETECTION OF COMMON ELEMENTS

Assignment:
Research on the complete chemical name of the following drugs
1. Aspirin
2. Paracetamol
3. Caffeine
4. Sulfamerazine
5. Chlorobutanol
6. Barbital sodium
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS

 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS -

ALKENES
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS -

ALKENES
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS -

ALKYNES
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS -

ALCOHOL
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

KETONE & ALDEHYDE
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

ETHER
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

AROMATIC HYDROCARBONS
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

CARBOXYLIC ACIDS
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

ESTERS
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

AMINE
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

AMIDE
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOL
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 3

Sulfamerazine

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 3

ORGANIC FUNCTIONAL GROUPS –

THIOETHER
 EXPERIMENT # 4

Hydrophilic Hydrophilic

Gentamicin

FUNCTIONAL GROUPS FOR DUG PHYSICOCHEMICAL

PROPERTY - SOLUBILITY
 EXPERIMENT # 4

lipophilic
Hydrophilic

FUNCTIONAL GROUPS FOR DUG PHYSICOCHEMICAL

PROPERTY - SOLUBILITY
 EXPERIMENT # 4

lipophilic lipophilic

Chlorazepate

Ciprofloxacin

FUNCTIONAL GROUPS FOR DUG PHYSICOCHEMICAL

PROPERTY - SOLUBILITY
 EXPERIMENT # 4
Acidic Basic

Aspirin
Sulfamethoxazole

FUNCTIONAL GROUPS FOR DUG PHYSICOCHEMICAL

PROPERTY – ACIDITY/BASICITY
 EXPERIMENT # 4

LESS SOLUBLE MORE SOLUBLE

1 polar functional 3 polar functional

groups groups

FUNCTIONAL GROUPS FOR DUG PHYSICOCHEMICAL

PROPERTY – QFR
 EXPERIMENT # 4

FUNCTIONAL GROUPS FOR DUG PHYSICOCHEMICAL

PROPERTY – Lipophilic and Hydrophilic drugs
 EXPERIMENT # 4

FUNCTIONAL GROUPS FOR DUG PHYSICOCHEMICAL

PROPERTY – Acidic and Basic Drugs