Drugs that People with Long QT Syndrom e Need to Avoid

The drugs listed below should be avoided by people who either have or are suspected of having Long QT
Syndrome. These drugs are suspected inducers of Torsades de Pointes, a potentially lethal ventricular
arrhythmia often connected to Long QT Syndrome. They are also suspected in causing the acquired form of
Long QT Syndrome.

There are more drugs than those listed in the table that may cause Torsades de Pointes or other problematic
arrhythmias in individuals who have Long QT Syndrome. It is recommended that patients ask their doctor or
pharmacist to run a “QT safety check” on any drug before using it.

For more information about the Long QT Drugs to Avoid List, please visit us at:
http://www.Long-QT-Syndrom e.com

Generic Name Brand Name Class/Clinical Use

Albuterol Ventolin® Bronchodilator / Asthm a
Albuterol Proventil® Bronchodilator / Asthm a
Alfuzosin Uroxatral® Alpha1-blocker / Benign prostatic hyperplasia
Dopam inergic/Anti-viral / Anti-infective/
Am antadine Sym m etrel®
Parkinson's Disease
Am iodarone Cordarone® Anti-arrhythm ic / abnorm al heart rhythm
Am iodarone Pacerone® Anti-arrhythm ic / abnorm al heart rhythm
Am phetam ine/dextroam phetam ine Adderall® CNS stim ulant / ADHD
Arsenic trioxide Trisenox® Anti-cancer / Leukem ia
Atom oxetine Strattera® norepinephrine reuptake inhibitor / ADHD
Azithrom ycin Zithrom ax® Antibiotic / bacterial infection
Bepridil Vascor® Anti-anginal / heart pain
Chloral hydrate Noctec® Sedative / sedation/ insom nia
Chloroquine Arelan® Anti-m alarial / m alaria infection
Anti-psychotic/ Anti-em etic / schizophrenia/
Chlorprom azine Thorazine®
nausea
Cisapride Propulsid® GI stim ulant / heartburn
Clarithrom ycin Biaxin® Antibiotic / bacterial infection
Cocaine Cocaine Local anesthetic /
Disopyram ide Norpace® Anti-arrhythm ic / abnorm al heart rhythm
Dobutam ine Dobutrex® Catecholam ine / heart failure and shock
Dofetilide Tikosyn® Anti-arrhythm ic / abnorm al heart rhythm
Dolasetron Anzem et® Anti-nausea / nausea, vom iting
Dom peridone Motilium ® Anti-nausea / nausea
Dopam ine Intropine® Anti-arrhythm ic / abnorm al heart rhythm
Sedative;Anti-nausea / anesthesia adjunct,
Droperidol Inapsine®
nausea
Bronchodilator, decongestant / Allergies,
Ephedrine Broncholate®
sinusitis, asthm a
Bronchodilator, decongestant / Allergies,
Ephedrine Rynatuss®
sinusitis, asthm a
catecholam ine, vasoconstrictor / anaphylaxis,
Epinephrine Prim atene®
allergic reactions
 catecholam ine, vasoconstrictor / anaphylaxis,
Epinephrine Bronkaid®
allergic reactions
Antibiotic;GI stim ulant / bacterial infection;
Erythrom ycin Erythrocin®
increase GI m otility
Antibiotic;GI stim ulant / bacterial infection;
Erythrom ycin E.E.S.®
increase GI m otility
Felbam ate Felbatrol® Anti-convulsant / seizure
Fenfluram ine Pondim in® Appetite suppressant / dieting, weight loss
Flecainide Tam bocor® Anti-arrhythm ic / abnorm al heart rhythm
Foscarnet Foscavir® Anti-viral / HIV infection
Fosphenytoin Cerebyx® Anti-convulsant / seizure
Gatifloxacin Tequin® Antibiotic / bacterial infection
Granisetron Kytril® Anti-nausea / nausea and vom iting
Halofantrine Halfan® Anti-m alarial / m alaria infection
Haloperidol Haldol® Anti-psychotic / schizophrenia, agitation
Ibutilide Corvert® Anti-arrhythm ic / abnorm al heart rhythm
Indapam ide Lozol® Diuretic / stim ulate urine & salt loss
Isoproterenol Isupres® Catecholam ine / allergic reaction
Isoproterenol Medihaler-Iso® Catecholam ine / allergic reaction
Isradipine Dynacirc® Anti-hypertensive / high blood pressure
Levalbuterol Xopenex® Bronchodilator / asthm a
Levofloxacin Levaquin® Antibiotic / bacterial infection
Opiate agonist / pain control, narcotic
Levom ethadyl Orlaam ®
dependence
Lithium Eskalith® Anti-m ania / bipolar disorder
Lithium Lithobid® Anti-m ania / bipolar disorder
Mesoridazine Serentil® Anti-psychotic / schizophrenia
Metaproterenol Alupent® Bronchodilator / asthm a
Metaproterenol Metaprel® Bronchodilator / asthm a
Opiate agonist / pain control, narcotic
Methadone Dolophine®
dependence
Opiate agonist / pain control, narcotic
Methadone Methadose®
dependence
Methylphenidate Ritalin® CNS stim ulant / ADHD
Methylphenidate Concerta® CNS stim ulant / ADHD
Midodrine ProAm atine® Vasoconstrictor / low blood pressure, fainting
Moexipril/HCTZ Uniretic® Anti-hypertensive / high blood pressure
Moxifloxacin Avelox® Antibiotic / bacterial infection
Nicardipine Cardene® Anti-hypertensive / high blood pressure
Vasconstrictor, Inotrope / shock, low blood
Norepinephrine Levophed®
pressure
Octreotide Sandostatin® Endocrine / acrom egaly, carcinoid diarrhea
Ondansetron Zofran® Anti-em etic / nausea and vom iting
Pentam idine NebuPent® Anti-infective / pneum ocystis pneum onia
Pentam idine Pentam ® Anti-infective / pneum ocystis pneum onia
Phenterm ine Fastin® Appetite suppressant / dieting, weight loss
Phenterm ine Adipex® Appetite suppressant / dieting, weight loss
Vasoconstrictor, decongestant / low blood
Phenylephrine Neosynephrine®
pressure, allergies, sinusitis, asthm a
Phenylpropanolam ine Dexatrim ® Decongestant / allergies, sinusitis, asthm a
Phenylpropanolam ine Acutrim ® Decongestant / allergies, sinusitis, asthm a
Pim ozide Orap® Anti-psychotic / Tourette's tics
Procainam ide Pronestyl® Anti-arrhythm ic / abnorm al heart rhythm
Procainam ide Procan® Anti-arrhythm ic / abnorm al heart rhythm
Pseudoephedrine PediaCare® Decongestant / allergies, sinusitis, asthm a
Pseudoephedrine Sudafed® Decongestant / allergies, sinusitis, asthm a
Quetiapine Seroquel® Anti-psychotic / schizophrenia
Quinidine Quinaglute® Anti-arrhythm ic / abnorm al heart rhythm
Quinidine Cardioquin® Anti-arrhythm ic / abnorm al heart rhythm
Risperidone Risperdal® Anti-psychotic / schizophrenia
Ritodrine Yutopar® Uterine relaxant / prevent prem ature labor
Salm eterol Serevent® Sym pathom im etic / asthm a, COPD
Sibutram ine Meridia® Appetitie suppressant / dieting, weight loss
Sotalol Betapace® Anti-arrhythm ic / abnorm al heart rhythm
Sparfloxacin Zagam ® Antibiotic / bacterial infection
Tacrolim us Prograf® Im m unosuppressant / Im m une suppression
Tam oxifen Nolvadex® Anti-cancer / breast cancer
Telithrom ycin Ketek® Antibiotic / bacterial infection
Terbutaline Brethine® Bronchodilator / asthm a
Thioridazine Mellaril® Anti-psychotic / schizophrenia
Tizanidine Zanaflex® Muscle relaxant /
Vardenafil Levitra® phosphodiesterase inhibitor / vasodilator
Venlafaxine Effexor® Anti-depressant / depression
Voriconazole VFend® Anti-fungal / anti-fungal
Ziprasidone Geodon® Anti-psychotic / schizophrenia

Perm ission to publish this inform ation was obtained from :

The University of Arizona Health Sciences Center
http://www.torsades.org

This list was last updated April, 2004

For the m ost recent publication, please visit http://www.torsades.org

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