CALAS RLAT Study Guide

Diseases of Laboratory Animals

Study Links:

1. AAALAC guidelines for use of live amphibians and reptiles in field and Laboratory
Research: https://www.aaalac.org/pub/?id=E90180D2-EE29-8F8B-A493-AC0C8F911AAC
2. Canadian Council on Animal Care Training Modules: https://www.ccac.ca/en/training/modules/animals-housed-in-vivaria-
stream/ https://www.ccac.ca/en/training/modules/fish-stream.html https://www.ccac.ca/en/training/modules/animals-
3. CCAC Guide to the Care and Use of Experimental Animals, Vol 1,2nd Edition:
https://www.ccac.ca/Documents/Standards/Guidelines/Experimental_Animals_Vol1.pdf
4. CCAC Guidelines: Mice: https://www.ccac.ca/Documents/Standards/Guidelines/CCAC_Guidelines_Mice.pdf
5. CCAC Guidelines: Rats: PDF
6. CCAC Guidelines: Zebrafish: Draft PDF CCAC Guidelines: Rodents, Dogs, Cats, Gerbils, Guinea Pig, Hamster, NHP’s, Rabbit,
Ferret, Reptiles, Amphibians, Avian (pigeons, doves, waterfowl, other avian species)
https://www.ccac.ca/en/standards/guidelines/types-of-animals.html
7. CCAC Guidelines (Zebra Fish, Salmonids) : https://www.ccac.ca/en/training/modules/fish-stream.html ( Salmonids)
https://zfin.org/zf_info/zfbook/zfbk.html (Zebra Fish)
8. CCAC Guidelines :General (Farm Animals) AND Species Specific (Farm Animals – Dairy and Beef cattle, Sheep and Goats, Pigs,
Poultry) : https://www.ccac.ca/Documents/Standards/Guidelines/Farm_Animals.pdf
9. CCAC Guidelines on: Antibody Production https://www.ccac.ca/Documents/Standards/Guidelines/Antibody_production.pdf
*new link
10. CCAC: housed-in-vivaria-stream/infectious-diseases.html
11. CALAS Manual: Module 4, Chapter 8; Diseases of Laboratory Animals; pg 235 to 256 only
12. CALAS Manual: Module 4, Chapter 4; Bioexclusion and Barriers; pg 113 and 114 ( to the end of Risk assessment)
13. Merck Veterinary Manual: Zoonotic Diseases; https://www.merckvetmanual.com/public-health/zoonoses
14. Diseases of Research Animals - DORA. University of Missouri - Comparative Medicine Program and IDEXX-BioResearch.
http://dora.missouri.edu/
15. Charles River Infectious Agent Information: https://www.criver.com/products-services/research-models-services/animal-
health-surveillance/infectious-agent-information?region=3601 *new link
16. NC3Rs https://nc3rs.org.uk/

Study Outline:

Primary Species (Mice, Rats and Zebrafish) are weighted at 80% of exam questions for species specific information requirements.
Secondary Species (Salmonids, Cats, Dogs, Gerbils, Guinea pigs, Hamsters, NHPs, Rabbits, Ferrets, Reptiles, Amphibians, Farm
Animals (cattle, sheep, goats, pigs, poultry), Avian (pigeons and doves, waterfowl, other avian species) are weighted at 20% of exam
questions for species specific information requirements.

1 to 8: These are species specific documents that all have relevant information on multiple subtopics in this core competency.
9: Antibody production
10: Infectious disease overview
11: and 12: Several core competency sub topics covered in this material
13: Overview of Zoonoses; Pathogens and Host species in Zoonoses; Transmission of Zoonoses
14: Disease information on primary and some secondary species
15: Disease information on primary and some secondary species
16: Source of information on Health Status monitoring and Quarantine

February 16th,2020