The HYALUDERM range HYALUDERM

FACIAL REJUVENATION
HYALUDERM
0,5ml
HIGH PERFORMING DERMAL FILLER
HYALUDERM 2,0% - 0,5 ml
0.5 ml sterile syringe with Needle 30 G

HYALUDERM
1,0ml
NEW
HYALUDERM 2,0% and HYALUDERM 2,5% - 1,0 ml
1.0 ml sterile syringe with Needle 30 G HIGH VISCOSITY
2,5 %
HYALUDERM
2,0ml

HYALUDERM 2,0% - 2,0 ml

2.0 ml sterile syringe with Needle 30 G

BOX OF 6 SYRINGES BOX OF 1 SYRINGE

Reference HYALUDERM 2.0% RANGE Reference HYALUDERM 2.5% RANGE

VD112010 1.0 ml – box of 1 syringe VD112510 1.0 ml – box of 1 syringe

VD162010 1.0 ml – box of 6 syringes VD162510 1.0 ml – box of 6 syringes

VD112020 2.0 ml – box of 1 syringe

HYALUDERM 2.0 % NaHA
VD162020 2.0 ml – box of 6 syringes

VD112005 0.5 ml – box of 1 syringe

HYALUDERM 2.5% NaHA
VD162005 0.5 ml – box of 6 syringes
VD1 M0033 071101

M E D I C A L D E V I C E M A N U FA C T U R E R
HYALUDERM 2.0 % NaHA HYALUDERM 2.5% NaHA

L C A P H A R M A C E U T I C A L Natural Sodium hyaluronate 2% Natural Sodium hyaluronate 2.5%

HIGH QUALITY - MADE IN FRANCE

9, allée Prométhée - F - 28000 Chartres - France - Phone : (33) 02 37 33 39 30 - Fax : (33) 02 37 33 39 39

l c a @ l c a - p h a r m a . c o m L C A P H A R M A C E U T I C A L
Public limited company with capital of 185 164,57 € - R.C.S. : Chartres B 311 274 401 - N° VAT : FR 44 311 274 401
Does not contain any animal protein
GB
 PRESENTATION
HYALUDERM comes in two concentrations of
sodium hyaluronate :
- 2.0% for moderately deep wrinkles

NaHA 2,0%

NaHA 2,5%
S O D I U M H YA L U R O N AT E
- 2.5% for more severe, longer and deeper wrinkles
(below or equal to 2 mm)

MECHANISM

HYALUDERM 2.0 %

HYALUDERM 2.5%
OF ACTION
W E A P O N

HYALUDERM is used during intradermal procedures

for lip augmentation.
For the smoothing of wrinkles, HYALUDERM adds
fullness to the wrinkle without spreading into the
hypodermis. It immediately, easily and rapidly
corrects wrinkles and scars.
A N T I - A G E I N G

HYALUDERM enhances the volume and contour

of lips.

INDICATIONS
• HYALUDERM 2.0% is indicated for the treatment of
moderate wrinkles and fine lines of the face and for
the enhancement of lips.
PRODUCT ORIGIN • HYALUDERM 2.5% is indicated for the treatment of
deep wrinkles and folds of the face.
HYALUDERM
N E W

• HYALUDERM is specifically recommended for : FACIAL REJUVENATION

• HYALUDERM is an intradermal,
HIGH PERFORMING DERMAL FILLER

COMPOSITION • Smoothing wrinkles and folds

viscoelastic, sterile, apyrogenic, transparent - Infraorbital wrinkles
structuring gel composed of genetically - Perioral rhytides
Sodium engineered sodium hyaluronate with a - Upper lip rhytides
T H E

hyaluronate (FB) high molecular weight, in accordance - Lower face

with the European Pharmacopeia. No - Crow’s feet
animal protein is contained in HYALUDERM. - Marionette lines
Sodium
- Forehead lines
chloride • HYALUDERM is a natural derivative of - Glabellar lines
hyaluronic acid found in the extracellular - Nasolabial fold
matrix of various types of connective tissue Deficient skin tissue should be supple and easily
Water for in the human body, particularly the skin. stretched for the defects to be observed.
injection The hyaluronic acid polymers (polysac-
charides) are essential for the metabolism L I P A U G M E N TAT I O N
• HYALUDERM 2.0% enhances the volume and WRINKLES SMOOTHENING
of skin and vital to its hydration contour of the lips and cheeks. HYALUDERM NaHA
and elasticity.

L C A P H A R M A C E U T I C A L
• HYALUDERM is an intradermal, viscoelastic
structuring gel composed of genetically
engineered sodium hyaluronate available in
a single-use, luer lock, prefilled glass syringe :
HYALUDERM 2.0% : 0.5 ml, 1.0 ml and 2.0 ml

NaHA

GENETIC ENGINEERING
HYALUDERM 2.5% : 1.0 ml

HYALUDERM is sterilised by steam autoclave

in an individual sterility protector.

W E A P O N
A single-use, sterile 30g intradermal

HYALUDERM
injection needle is provided in an individual
sterility protector.

Skin tests

A N T I - A G E I N G
are not

necessary
ADVANTAGES due to the
Does not contain any
animal protein
bio-
RESULTS

N E W
availability • The rheological properties of
HYALUDERM HYALUDERM enable the intradermal
anatomical space to be rapidly
FACIAL REJUVENATION
HIGH PERFORMING DERMAL FILLER
of sodium

T H E
reconstituted. HYALUDERM eliminates
folds and reduces depressions in the skin
due to wrinkles.
hyaluronate
THE EPIDERMIS

THE DERMIS

A D VA N TA G E S
100% bioavailable
L I P A U G M E N TAT I O N
WRINKLES SMOOTHENING
THE Very well-tolerated
SUBCUTANEOUS
HYALUDERM NaHA
TISSUE

L C A P H A R M A C E U T I C A L
 HYALUDERM
FACIAL REJUVENATION
HIGH PERFORMING DERMAL FILLER

A D VA N TA G E S
Easy to inject due to
adaptation viscosity
(pseudoplasticity)

NON-CROSS-LINKED
W E A P O N

L I P A U G M E N TAT I O N
WRINKLES SMOOTHENING
HYALUDERM NaHA

L C A P H A R M A C E U T I C A L
A N T I - A G E I N G

RHEOLOGY AND BEAUTY

• The innovative rheological properties • It is recommended that patients with
of HYALUDERM provide excellent cosmetic very damaged skin (over exposure to
• HYALUDERM is a solution of high results and enable the intradermal sunlight, smoking, medication or dieting)
viscosity for intradermal injection : anatomical space to be rapidly use HYALUDERM 2.5% as viscosupplement
reconstituted. HYALUDERM eliminates injections to the intercellular spaces of the
Raw material : Sodium Hyaluronate. European folds and reduces depressions in the skin deficient dermis.
Pharmacopaeia Pharmaceutical Grade due to wrinkles.
To obtain an ideal degree of correction,
Origin : Genetic engineering/Non-cross-linked
one or several additional injections of
N E W

Perfectly clear and transparent HYALUDERM may be necessary.

Efficacy lasts 6 +- 2 months. The treatment
Sterile, apyrogenic and non-cytotoxic
can be repeated according to needs.
for subcutaneous tissues

Physiological pH 7.2
T H E

Wrinkle smoothing implants

Osmolarity : 360 mOs/kg
Rheological comparison
1000000
Sterile (autoclave / steam)
Restylane
NaHA

Hylaform
Dynamic viscosity at rest (25°C - 0.01 s ) -1 100000
Hyaluderm 2%
100 000 mPa.s (NaHA 2.0%) A D VA N TA G E S Hyaluderm 2.5%
Dynamic viscosity (mPa.s)

170 000 mPa.s (NaHA 2.5%) 10000

Does not contain any

High molecular weight : 2 400 000 Daltons Chemical Agent or any 1000

High concentration : 2.0% NaHA (20 mg/mL) particles in suspension 100

2.5% NaHA (25 mg/mL)
10
Volume per syringe : 0.5 mL ; 1.0 mL ; 2.0 mL 0,1 1 10 100 1000 10000
Shear rate (s-1)
Storage : room temperature