DISTRICT RESOURCE CENTRE

MAHBUBNAGAR
B.Sc., PRE-FINAL EXAMINATIONS - JAN / FEB -2011
Time :3 Hours CHEMISTRY Paper – IV Max Marks : 100

SECTION – A 4x15= 60

Answer any two bits from each question.

1. (a) Write the Principle involved in Solvent extraction and explain following.
(i) Batch extraction (ii) Continuous extraction.
(b) Determine the term Absorbence and explain how manganses in KMnO4 is
determined by Application of Beer Lamberts law.
(c) Define chemical Shift Value. And wirte NMR Spectra for 1, 1, 2 - tribromo
ethane.
(d) Explain Modes of vibration by using IR spectro scopy.
2. (a) Give the synthesis and there peutic activity of the following drugs
(i) L - Dopa (ii) Omeprazole
(b) Explain terms
(i) Pharmaco Kinetics (ii) Pharmaco Dynamics (iii) Metabolities
(c) Write synthesis and therapentic activity of the following.
(i) Ciprofloxacin (ii) Chloroquin
(d) What is need for the conversion of drug into medicine? Explain the
formulaiton of Albuterol.
3. (a) What is Zeiglar Natta catalyst? Explain the process of polymerisation of
Ethylene in presence of Zeiglar Natta catalyst.
(b) Explain the terms number average weight & average molecular weight what
is ment by degree of polymerisation.
(c) What are nano-materials explain their importance in technological Application.
(d) Explain hydrolysis of ester by using Acid base catalysed reaction.
SECTION – B 4x5= 20
4. (a) Write different types of paper chromatography.
(OR)
(b) Write principle and application of HPLC.
5. (a) Write the spectral data of Para nitro aniline by NMR, IR and UV-visible data.
(OR)
(b) Rf value define preparation of Plates in T.L.C
6. (a) Explain electronic transittion in electronic spectroscopy.
(OR)
(b) What is polarizability write selection rules for Raman spectrosocopy.
7. (a) Write the different stages of replication of HIV virus in human bady.
(OR)
(b) What is a generic name and a trade name give three examples.
8. (a) Write the structures of Ampicillin and Amoxycillin.
(OR)
(b) What are solid dosage forms? Write a note on tablets with example.
9. (a) Define the following with a suitable example.
(i) Insceticide (ii) fungicide (iii) Herbicide
(OR)
(b) Write microwave and ultrasound assisted green synthesis of following.
(i) Aldol condensation (ii) Diels-Alder reaction (iii) Willaimson synthesis
10. (a) Equal molecular of M.Wt. 50,000 and 10,000 are mixed, calculate the number
average and weight average molecular weight.
(OR)
(b) Explain following terms (a) Tacticity (b) Atacticity
11. (a) What are fullarenes? What are their use.
(OR)
(b) Preparation of Teflon and PVC
12. (a) What are enzymes? Write the characteristics of enzyme catalysis.
(OR)
(b) Discuss the osmatic pressure method to determine the molecular weight of
polymer.
 DISTRICT RESOURCE CENTRE
MAHBUBNAGAR
B.Sc., PRE-FINAL EXAMINATIONS - JAN / FEB -2011
Time :3 Hours CHEMISTRY Paper – IV Max Marks : 100

SECTION – A 52 Marks
@y˚ì s¬ +&ÉT _{Ÿ\qT Áyêj·T+&ç .
1. (a) Á<ëeDÏ ìwüÿs¡¸D˝À Ç$T&ç ñqï dü÷Á‘·eTT Áyêj·TTeTT. ÁøÏ+~ |ü<ë\qT $e]+|ü⁄eTT.
(i) u≤#Y ìwüÿs¡¸D (ii) ìs¡+‘·s¡ ìwüÿs¡¸D
(b) XÀwüø+£ |ü<+ä qT ìs¡«∫+∫, es¡í |ü≥ e÷|üq |ü<‹›ä <ë«sê bı{≤wæjT· + |üsêà+>∑H{˚ Ÿ Á<ëeD+˝À
>∑\ e÷+>∑˙dt jÓTTø£ÿ uÛ≤sêìï ìsê∆]+#·TeTT. (Beer-Lamberls)
(c) s¡kÕj·Tq kÕúq ÁuÛ+Ñ X¯+qT ìs¡«∫+|ü⁄eTT. 1, 1, 2 ` tribromoethan jÓTTø£ÿ NMR es¡|í ≥ü +qT
Áyêj·T+&ç.
2. (a) á ÁøÏ+~ Wwü<ëÛ \ jÓTTø£ÿ dü+X‚w¢ Dü eT]j·TT Wwü<äÛ >∑TDeTTqT ‘Ó\T|ü⁄eTT.
(i) L - Dopa (ii) zyéT Á|üCÀ˝Ÿ
(b) á ÁøÏ+~ |ü<ë\qT $e]+|ü⁄eTT.
(i) bòÕs¡àø√¬øq ’ {Ïø‡˘ (ii) bòÕs¡àø√&Óq’ $Tø˘‡ (iii) yÓT≥uÀ˝…{’ Ÿ‡
(c) á Wwü<ëÛ \ jÓTTø£ÿ dü+X‚w¢ Dü eT]j·TT Wwü<äÛ >∑TDeTT\qT Áyêj·T+&ç.
(i) dæÁbıbòÕø¢ ‡Ï Hé (ii) ø=¢s=øÏ«Hé
(d) @<˚ì ˇø£ Á&É>q¥ T Wwü<ëÛ +>± s¡÷bı+~+#ê*‡q ÄeX¯´ø£‘· @$T{Ï? Ä˝ŸãT´{Ïsê˝Ÿ (Albuterol)
jÓTTø£ÿ s¡÷bı+~+#˚ $<ÛëHêìï Áyêj·T+&ç.
3. (a) J>∑s¢ `Y Hê{≤ ñÅ‘Œ˚ s¡ø+£ n+fÒ @$T{Ï? á ñÅ‘Œ˚ s¡ø+£ düeTø£+å ˝À Ç~∏©Hé jÓTTø£ÿ bı*eTØø£sD¡ +
$<ÛëHêìï $e]+|ü⁄eTT.
(b) dü+U≤´ düsêdü] nDTuÛ≤s¡eTT, uÛ≤s¡ düsêdü] nDTuÛ≤sê\qT $e]+|ü⁄eTT. nDT|üP+Jø£sD¡
rÁe‘· nq>± H˚$T?
(c) HêH√ |ü<ës¡\ú T nq>± H˚$T? kÕ+πø‹ø£ XÊg nqTes¡HÔ ê\˝À M{Ï ÁbÕeTTK´‘·qT $e]+|ü⁄eTT.
(d) mdüsº Y jÓTTø£ÿ »\ $X‚w¢ Dü qT ÄeT¢ø±å s¡ ñÅ‘Œ˚ s¡D\ <ë«sê $e]+#˚ #·s´¡ \T Áyêj·T+&ç.
SECTION – B 8x6=48

4. (a) $$<Ûä s¡ø±\ ù||üsY Áø√eT{À Á>∑|ìæò $e]+|ü⁄eTT.

(OR)
(b) H.P.L.C jÓTTø£ÿ dü÷Á‘·eTT eT]j·TT nqTes¡HÔ ê\qT Áyêj·T+&ç.
5. (a) bÕsêHÓÁ’ {À mì*Hé jÓTTø£ÿ es¡í |ü≥ yê´U≤´qeTTqT UV, NMR, IR es¡í |ü≥ Ä<Ûë]‘·
$\Te\qT Áyêj·T+&ç.
 (OR)
(b) Rf $\TeqT ìs¡«∫+|ü⁄eTT eT]j·TT T.L.C ˝À ù|{¢ Ÿ\ ‘·j÷· ]ì Áyêj·T+&ç.
6. (a) m˝Åø±ºìø˘ es¡í |ü≥ $C≤„q+˝À >∑\ m\Åø±ºHé |ü]es¡qÔ s¡ø±\qT Áyêj·T+&ç.
(OR)
(b) Á<ÛTä eDo\‘· uÛ≤eqqT ìs¡«∫+∫ sêeTHé es¡í |ü≥ $C≤„q+˝À >∑\ es¡D ìj·Te÷\qT Áyêj·T+&ç.
7. (a) e÷qe X¯Øs¡+˝À >∑\ HIV - yÓs’ d¡ t jÓTTø£ÿ Á|ü‹ s¡÷|ü dü+X‚w¢ Dü jÓTTø£ÿ $$<Ûä <äX\¯ qT
Áyêj·T+&ç.
(OR)
(b) C…q]ø˘ eT]j·TT yê´bÕs¡ Hêe÷\qT $e]+∫, eT÷&ÉT ñ<ëVü≤s¡D\‘√ $e]+#·+&ç.
8. (a) Ä+|æd*æ Hé eT]j·TT ÄyÓ÷C…d’ *æ Hé (Amoxycillin) ìsêàD≤\qT Áyêj·T+&ç.
(OR)
(b) |òTü q Wwü<äÛ s¡÷bÕ\T @$? >√∞\ (Tablets) qT >∑÷]Ã ñ<ëVü≤s¡D\‘√ $e]+|ü⁄eTT.
9. (a) ÁøÏ+~ yê{Ïì ìs¡«∫+∫ dü]jÓTÆ q ñ<ëVü≤s¡D Áyêj·T+&ç.
(i) ÁøÏ$T dü+Vü≤]DÏ (ii) •©+Á<Ûøä ±]DÏ
(iii) ‘·T+>∑ HêX¯ø±\T (ôV≤]“ôd&
’ )é Herbicides
(OR)
(b) yÓTÁÆ ø√ ‘·s+¡ >±\T eT]j·TT ÄÅ˝≤º <Û«ä ì ‘·s+¡ >±\qT ñ|üj÷Ó –+∫ ÁøÏ+~ düyT˚ àfi¯Hê\ Vü≤]‘·
s¡kÕj·TqXÊg+qT $e]+|ü⁄eTT.
(i) Ä˝≤º˝Ÿ dü+|òTü qq+ (ii) &û˝Ÿ‡` Ä\¶sY #·s´¡ (iii) $*j·T+düHé dü+X‚w ¢ Dü
10. (a) ˇπø $<Ûyä TÓ qÆ nDTe⁄\T es¡Tdü>± 50,000 eT]j·TT 10,000 nDTuÛ≤s¡+ ø£*– $TÁX¯eT+
s¡÷|ü+˝À e⁄HêïsTT. nsTT‘˚ yê{Ï jÓTTø£ÿ dü+U≤´ düsêdü] nDTuÛ≤s¡+ eT]j·TT uÛ≤s¡ düsêdü]
nDTuÛ≤s¡+\qT ˝…øÿÏ +#·+&ç.
(OR)
(b) ÁøÏ+~ |ü<ë\qT ìs¡«∫+|ü⁄eTT.
(i) {≤øχdæ{Ï (ii) n{≤øÏd º {æ Ï
11. (a) |ò⁄ü \¢]Hé‡ nq>± H˚$T? yê{Ï ñ|üj÷Ó >∑eTT Áyêj·T+&ç.
(OR)
(b) f…bÕò H¢ é ( Teflon) eT]j·TT P.V.C ‘·j÷· ] Áyêj·T+&ç.
12. (a) m+C…y’ Té \T nq>± H˚$T? m+C…y’ Té ñÅ‘Œ˚ s¡DeTT ( emzyme catalysis) jÓTTø£ÿ \ø£Då ≤\qT
Áyêj·TTeTT.
(OR)
(b) Á<äyê_Ûdsü D¡ |”&qÉ |ü<‹›ä <ë«sê bÕ*eTsY nDT uÛ≤sê\qT ìs¡sí TT+#˚ $<ÛëHêìï $e]+|ü⁄eTT.