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Abstract
Acetylsalicylic acidC9H9O4, known as Aspirin, is one of the popular and
versatile medicines that cure diseases. It is considered a powerful drug for
relieving pain (analgesic), reducing fever (antipyretic), and reducing swelling
(anti-inflammatory). The synthesis of acetylsalicylic acid is derived from
salicylic acid which can be extracted in willow trees and allowing it to react
with acetic anhydride and a catalyst through the principle of crystallization.
I. Introduction
Limiting reagent:
Acetic anhydride:
2.0081 g C7H6O3×1 mol138.12 g C7H6O3×102.09 g C4H6O31 mol×1 ml 1.082
g=1.37 ml C4H6O3
Salicylic acid:
5.00 ml C4H6O3×1.082 g1 ml×1 mol102.09 g C4H6O3×138.12 g C7H6O31
mol=7.3193 g C7H6O3
Theoretical yield:
Percentage yield:
2.6310 g synthesized aspirin2.6193 g C9H9O4×100=100.45%