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Dennis McKenna is one of the leading figures in the global psychedelic and
scientific communities investigating plant entheogens and indigenous plant
medicines. He was involved with the “Hoasca Project” studying ayahuasca usage by
members of the Church de Vegetal and recently issued the manifesto “Ayahuasca
and Human Destiny”. Along with his late brother Terence, Dennis co-wrote the
book “The Invisible Landscape” which revealed their psychedelically influenced
insights into the nature of reality and spacetime they received during ‘The
experiment at La Cholerra’ in South America in 1971 (later recounted in
Terence’s book “True Hallucinations”). Here, he talks at length about what
happened at La Cholerra and how that influenced his later work with Ayahuasca.
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RAK: Dennis you received your doctorate in 1984, so you've been studying
plant entheogens for over twenty years now professionally. I'd like to
backtrack just a bit to talk about how you got into the psychedelic and plant
sacrament culture. In your brother Terence's book “True Hallucinations” he
details your adventures into Amazonian shamanism, could you tell us a bit
about those times and how you and Terence began?
DENNIS: Right. “True Hallucinations” was Terence's book but I was one of
the main subjects in it. We wrote together a book in 1975 called “The
Invisible Landscape” which we were co-authors on. That was an attempt to kind
of lay out in scientific terms and make sense of our experiences at La
Cholerra. But True Hallucinations was more like a novel version of that. The
Invisible Landscape was like a pseudo-scientific screed in a way, and True
Hallucinations was more like a travel novel of our adventures in the Amazon
kind of thing.
RAK: I guess what interested me about all this is that you've become a
leading scientist in this field but before that as the books reveal there was
this thirst for adventure, this calling to know more about indigenous people
and the plant medicines. Both The Invisible Landscape and True Hallucinations
reveal some intense encounters with plant medicines, could you explain what
happened there at La Cholerra?
And yes, we had a thirst for adventure but our adventure at La Cholerra really
grew out of our preoccupation with DMT. We were both hippies in the 60s, in
Berkeley and the Haight-Ashbury and all that. Like everybody at that time in
that sort of countercultural movement we were interested in psychedelics. We
took LSD and thought that was interesting and so on. But unlike a lot of
people, for various reasons that I now view as fated, in a way, DMT came down
the pike.
DENNIS: They weren't big and they were unheard of in the States at the time.
RAK: They didn't exist in the States or they just weren't being used widely?
DENNIS: No. Not really. Psilocybin was a legendary substance that never
really showed up on the streets. Things showed up on the streets that
purported to be psilocybin, but they were LSD basically. Nobody knew how to
grow mushrooms at that time. It wasn't happening. What you got was frozen
store bought mushrooms that had been sprayed with LSD. It was totally fake,
nobody knew about it.
So we started taking these mushrooms and having lively conversations all the
time fuelled by mushrooms and fuelled by liberal ingestion of cannabis at all
times of the day and night. Cannabis was virtually legal in Colombia at that
time. We brought in a pound and a half of the best native bud we could lay out
hands on.
... And one of the aspects of taking the mushrooms was this sound that we
could hear at high doses. You could hear a sound at the edge of detection that
seemed to be a kind of high-pitched, electronic buzzing and popping sound.
It's the sound you can hear very strongly when you smoke DMT. The sound of
ripping cellophane, people describe it that way, or crumpling cellophane or
things like that.
We developed this idea that if you could listen to this sound, and not only
listen but imitate the sound, you could sing it, it was something that you
could imitate and if you tried to imitate it you reached a point where it sort
of locked on to this internal resonance. Initially it sounds stupid, y'know,
you're trying to follow a tune along and you're not getting it very well, but
at some point you would lock on to this, and then it would just pour out of
you. You couldn't even stop it.
What we were doing was not science - it was magic. We thought we were doing
science but we didn't know anything about science at the time. We set up what
we called an experiment, but what we should have really called a ritual.
Honestly it was a ritual but we had the idea that if we took a large dose of
mushrooms, along with ayahuasca and heard this sound, that we could generate
this standing wave form and that we could actually transfer that into the body
of a mushroom in a stable way so that it would be outside the body and it
would be sustained by it's own superconducting circuitry, and you would be
able to see it and be it at the same time. It would be, in a sense, an
artifact from beyond that you generate out of your own head. It would be a
super, transbiological artifact, translinguistic matter that would be meaning
itself fixed into a biological matrix.
DENNIS: (hesitates)... No... (laughs) No, not exactly! What we were trying to
do, essentially, if I can harken back to the basis of this in myth and
history, I mean the closest analogy to it is the Philosopher's Stone. We were
trying to recreate the Philosopher's Stone, which in some ways is the ultimate
artifact. That thing that exists and is both mind and matter and responds to
thought and is you and can do anything you can imagine, literally, anything
you can imagine.
And so we performed the experiment and what we postulated was going to happen
didn't happen, obviously. How could it happen? It didn't happen that the
mushroom would explode on a cloud of super-condensed glowing crystals and
leave a glowing violet disk in front of us, no. That's not what happened, you
know. That was the whole for result. That we'd just be able to get in the
saucer and fly away, and end History in the process.
RAK: It's a very grand ideal there, and I guess the immediate result was that
your MAO inhibitors were mixed up for a while there?
DENNIS: Totally fucked up for a while, that's one theory. I was completely
out of it for two weeks.
RAK: But were you in that zone, that completely hallucinogenic DMT zone
inside your head for two weeks?
DENNIS: No, no, what happened was... Well one theory is the MAO permanent
disruption of MAO brain chemistry for weeks, and that's one possibility. I'm
now not so sure that that's true. Because other people take mushrooms and
ayahuasca or they synergize mushrooms with beta-carbolines and things like
that any they don't go crazy. Invariably they don't go crazy.
I had this feeling that I had been literally smeared over creation by this
experiment that we'd done. I was literally a space cadet. What was happening
to me was I was experiencing this slow collapse over each 24 hour period from
the edges of the universe to a concentration. So that over each period, like
the first time, the first 24 period I was in the whole cosmos. And then the
second one it was like the galactic cluster...
And I've thought about it, of course. I've thought about it a lot since then,
and really the only model that really fits is not a biochemical model or a
pharmacological model. The only model that fits is a shamanistic initiation.
That's what happened to me.
I didn't ask for it. I wasn't prepared for it. But that's what happened.
Because in shamanic traditions in all cultures all over the world, there is
this notion of being literally torn apart and put back together - in a better
way than you were before. And I feel -- and I'm not a shaman, I'm not claiming
to be a shaman, I didn't ask to be a shaman -- but I got the initiation and I
do feel that ultimately it was a very integrative thing. It was a healing
thing that happened to me.
RAK: Do you think that then has influenced your future career as a scientist,
which is the Western shaman, in a way.
RAK: Could you then tell us a bit about the ‘Hoasca Project’ and some of
the other scientific explorations you've done with ayahuasca? What were the
results, that the receptors of the brain were improved? The serotonin
receptors?
DENNIS: In 1991 I was invited to a conference that the UDV had organized. And
the UDV had a medical studies section at the time. Although they're quick to
deny that ayahuasca is a drug but they still had a medical health section.
They were under scrutiny from the Brazilian government who was looking at
their practice and wondering should they allow this? Or should we prohibit it?
And what's going on, is this harmful or not? So they wanted to do an actual
biomedical study, and they wanted foreign researchers to do it.
I came away from that field trip with that idea, that we could develop a bio-
medical study [that eventually showed that] the receptors of the brain were
improved. Maybe we thought they would have an improved immune function, we
didn't really have any idea what it might be .
DENNIS: Uh, yeah, yeah. There has always been some degree of interest from
Big Pharma to look into Amazonian plants for potential sources of new
medicines. At one time I wanted to develop a standardized preparation of
ayahuasca and file an IND in the United States and do a clinical study to look
at it's potential for the treatment of alcoholism... But then I had an
epiphany a while back. The FDA is never going to approve and IND, that is, an
Investigational New Drug application for a plant that, for a medicine that not
only is a plant, but a plant that contains a controlled substance.
I'm still curious about ayahuasca and I still think science can tell us a lot
about ayahuasca. But I have given up my pharmaceutical ambitions to turn it
into a drug, or a drug that can be used clinically. I've gotten a strong
message that ayahuasca is a sacred thing and I don't want the pharmaceutical
industry to corrupt it. I think that those who need to find ayahuasca will
find it. I think ayahuasca will find those it needs to find.
RAK: How much of you as a scientist believes that the chemical structure [of
ayahuasca] can be replicated versus how much of it is the spirit of the plant,
the shaman or the practioner administering the plant that is involved in the
outcome?
RAK: Apart from the science, how do you feel about the countercultural
interest in ayahuasca and indigenous medicines that's really booming at the
moment globally?
DENNIS: I'm not sure how I feel about it. I think that it's sort of
inevitable. I think that in the global culture, in the world culture a great
many people are spiritually bereft. I think that the conventional religious
institutions and other type of institutions that have normally sustained
society are now seen to be simply empty, and without meaning, or actually
inimical to the survival of our species.
And I think there's a great deal of anxiety, whether it's expressed or not,
about the global crisis that we're in. And I think the people are turning to
indigenous traditions in search of something, something more meaningful.
RAK: You wrote the recent document from 2005, “Ayahuasca and Human
Destiny”, and I guess for me reading that it seemed a bit of a positive
manifesto of the potentials of ayahuasca for Westerners.
RAK: Do you think that the West is perhaps getting what it needs? In the last
50 years or so of Western history there's been the beatniks and marijuana,
acid and the hippies in the 60s, rave culture and ecstasy in the 80s and 90s,
and now in the 00's ayahuasca is coming in? It seems that every successive
generation needs to reconnect via some drug, and now it's going back to an
indigenous way?
RAK: Your late brother Terence was quite a prominent figure in the 90s
representing psychedelics in the rave scene, and he had a very positive agenda
as well.
DENNIS: Yeah, and really urging people, I think, to rediscover the sacred.
His whole notion of the Archaic Revival was right on, in a sense. And I think
that's what you're seeing with ayahuasca, it's not just the substances that
you have to rediscover, it's the sacredness and the context of their use, the
traditions. And so I think the interest in ayahuasca is encouraging in that
people are waking up to the fact that you have to rediscover not only the
substances but the context for their use and are looking to these archaic
traditions where people have developed over millennia ways to relate to these
plants and these substances.
RAK: It seems like a lot of the indigenous cultures are chasing the Western
dream of materialism at the moment, yet at the same time in the West people
are chasing the indigenous dream, so maybe it's balancing out.
DENNIS: That's right. And then there's the whole other aspect of the global
culture, what I call the Corporatist Fascists who basically want to control
everything and want to suppress both of these things because they think that
they should own the world. And that the rest of the world, that their job is
to be consumers and workers and shut up and not cause trouble.
RAK: You call ayahuasca in your manifesto, “Ayahuasca and Human Destiny”, a
‘Holy Grail for our species’, or a potential Holy Grail for our species. Do
you think it can heal the world?
RAK: It's Dominator Culture having it's last wrestle trying to control the
steering wheel.
DENNIS: Exactly. And they're very powerful, very dangerous and very ruthless.
RAK: Does it seem sort of ironic and yet balanced again that while Dominator
Culture's trying to wrest control, the spirit of the earth or of nature is
actually seeding all these things and going out again to try and regulate the
human monkey out of control?
DENNIS: Yeah, well, totally. I couldn't have said it better myself. This is
exactly what it's doing.
This has been an excerpt from a larger interview from the forthcoming
"Ayahuasca Sessions" anthology featuring conversations with curanderos,
shamans and Western plantworkers. It was first published in this format by
High Times magazine July 2007.