MCQ (Endocrine blok)

1. Regarding thyroid gland

a. its “false capsule” is derived from the deep cervical fascia T
b. it lies between the sternohyoid and sternothyroid muscle F
c. its isthmus is anterior to the 1st and 2nd tracheal cartilages F
d. it is supplied by the superior and inferior thyroid arteries T
e. it moves up and down during swallowing T

2. Berkenaan pengawalaturan ekspresi gen dalam eukariot

a. gabungan factor transkripsi spesifik pada DNA menentukan gen yang akan ditanskripsi
b. proses transkripsi berlaku secara aktif dalam heterokromatin
c. setiap promoter mengawalatur beberapa jeis gen
d. protein kawalatur boleh bergabung pada kawasan intron dalam DNA
e. ia menentykan penghasilan protein yng tertentu pada sesuatu masa
3. Berkenaan mutasi DNA
a. mutasi “silent” tidak merubah protein yang dibentuk
b. setiap mutasi menyebabkan penyakit
c. mutasi somatic menyebabkan penyakit genetic
d. ia belaku akibat kesilpaan aktiviti RNA polymerase
e. anemia sel sabit disebabkan oleh mutasi “missense”
4. Gluconeogenic substates include
a. glycerol
b. lactate
c. lysine
d. alanine
e. fatty acid
5. Regarding glycogen metabolism
a. it occur in the liver
b. UTP required for glycogenesis
c. Glycogen is synthesized as an unbranched polymer of lucose
d. Fed state activates glycogenolysis
e. Debranching enzyme deficiency causes Cori’s disease
6. Aldosterone secretion is stimulated by and increase in
a. blood volume
b. potassium intake
c. sodium intake
d. the activity of renin-angiotensin system
7. Glucocorticoid in the blood
a. Include cortisol
b. Increase the blood eosinophil count
c. Increase the total white cell count
d. Promote sodium reabsorption by the kidney
e. Suppress antibody formation
8. Secretion of GH
a. is from the post pituitary
b. is stimulated by growth hormone releasing hormone
c. ceases in adults
d. decreases following severe injury
e. increase when the blood glucose level fall
9. Hypothalamic releasing hormones influence the release of
a. thyrotrophin
b. oxytocin
c. pancreatic glucagons
d. testosterone
 e. hoemones for the control of ovulation
10. Vitamin 1,25-dihydoxycholecalciferal
a. increase the absorption of Ca2+ in the intestine
b. is essential for normal calcification in childhood
c. requires hepatic modification for activation
d. cannot be formed in the body
e. is formed more readily in dark than in light skinned people
11. Berkenaan glukagon
a. ia merencat kemasukan glucose ke dalam sel otot
b. disintesis oleh sel B pankrease
c. ia merangsang glikogenolisis di hepar
d. ia meningkatkan aras asid lemak bebas plasma
e. hiperglisemia merangsang sintesis dan rembesan
12. Insulin
a. merencat lipolisis di tisu adipos
b. merencat glikogenesis di otot
c. merangsang gluconeogeneis di ginjal
d. merencat katabolisme protein di otot
e. perlu untuk kemasukan ke dalam sel otot
13. Hyperglycemiahormones include
a. insulin
b. glucagon
c. glucocorticoids
d. epinephrines
e. growth hormones
14. Hormone produced by adrenal cortex
a. aldosteronee
b. androgen
c. adrenalin
d. adrenocorticophic hormone
e. estrogen
15. Regarding fatty acid synthesis
a. it occurs only in the liver
b. the major souce of carbon is dietary carbohydrates
c. translocation of citrate from mitochondria to cytosol is required
d. acetyl CoA carboxylase is the rate limiting enzyme
e. malate is the end product