Marc Foster, PhD

4700 Serra Drive

Fremont, CA 94538
925.321.3678
mf6592be@westpost.net
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SUMMARY
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Scientist with 10 years of experience with LCMS, 14 years of expertise with HPLC
, 9 years of industrial experience developing commercial, analytical instrumenta
tion and ten years of experience managing others. A talented bench chemist and
experienced laboratory supervisor with a Ph.D. from the University of Washington
in Analytical Chemistry. A passion for smooth laboratory operations through ca
reful observation of workflow, meticulous documentation of and adherence to work
processes and balanced thoughtful use of available resources.
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EXPERIENCE
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LIFE TECHNOLOGIES, Pleasanton, CA, Staff Scientist 04/2010 to now
* Developed validated methods for QC of custom oligonucleotides
* Developed AB5800 TOF/TOF methods for sequencing of custom oligonucleotide
s
* Trained staff members on HPLC
* Analyzed oligo impurities by Qstar Qtof LCMS (Analyst)

CODEXIS, Redwood City, CA, Staff Scientist 08/2006 to 08/2009

Codexis is a ten year old biotech startup creating novel, smarter enzymes that m
ake new industrial processes possible and existing processes faster, cleaner and
more efficient than commercial methods.
Sales of ~$15 million and ~300 people.
Supervised one RA, developed LC/GC/MS methods, purchased, and maintained equipme
nt. Conducted regular training sessions for all Codexis staff on separations and
GCMS.
*Studied workflow and increased Codexis overall production by increasing through
put.
*Identified, purchased and maintained instrumentation such as NMR, GC, GCMS, HPL
C and LCMS. Trained staff in the use and maintenance of this equipment.
*Developed high-throughput assays for cellular components of various strains of
microorganisms, particularly, organic acids, glycerides and sugars in support of
Analytical Biochemistry, Fermentation R&D and Cellular Engineering departments.
*Supported Quality Department by developing methods for QC and identifying inhib
itors in API Manufacturing by LC/MS and GC/MS.
EXCELLENT PACKINGS, LLC, Livermore, CA, President 04/2005 to 06/2006
Excellent Packings was a self-owned company which made and sold HPLC columns an
d consumables.
Manufactured, marketed and sold HPLC columns and consumables for HPLC.
EKSIGENT TECHNOLOGIES, Livermore, CA, Senior Scientist 06/2003 to 04/2005
Eksigent was a startup of ~40 people and sales of several million, that manufact
ured microfluidic HPLC systems. Eksigent was acquired by AB Sciex on 2/16/2010.

Developed instrumentation, columns, consumables and applications for capillary a

nd microfluidic based HPLC and MS systems. Presented results at conferences and
published work in journals.
*Built the first protoype 2D HPLC system for proteomic analysis
*Utilized ABI Qtrap for development of proteomic assays with NanoLC
*Developed packing procedure and hardware for capillary chiral columns and other
phases.
*Gave oral and poster presentations of work at Eksigent, internally and at confe
rences.
*Trained distributors on operation and maintenance of the HPLC systems.

RHEODYNE, Rohnert Park, CA, Manager, Science and Technology 09/1998 to 06/20
03
Rheodyne was a private company which produced more than 75% of the high pressure
valves used in commercial HPLC systems with sales of ~$25 million and just over
100 people.
Managed 2 senior scientists and one chemist. Managed all intellectual property.
Managed ~$0.5 million budget and capital expenditures. Evaluated performance o
f Rheodyne products and competitor's products. Developed new products.
*Designed and developed new HPLC hardware and applications for HPLC including a
valve for 20kpsi, a liquid-phase MUX type device and an active splitter for MS d
irected purification.
*Wrote technical papers and presented research at technical conferences.
*Managed activities of 2 senior scientists and 1 chemist.
*Managed IP with our patent attorney.
*Gave training sessions on MS, MS/MS and HPLC/MS.
*Aided in due diligence analysis of potential acquisitions.

ANATEL, Boulder, CO, Scientist 11/1996 to 08/1998

Anatel was the world's leading supplier of Total Organic Carbon Analyzers for se
miconductor fabs with sales of over $10 million and ~60 people.
Trained two scientists and developed new instrumentation.
*Developed new instrumentation for analysis of total organic carbon in high puri
ty water.
*Gave technical presentations at customer sites and conferences.
*Co-developed an on-line instrument for advanced semiconductor waters with an LO
D of 5 parts-per-trillion.
*Conceived new instrument for order of magnitude faster response time.
*Introduced new theory to account for unknown conductive species in irradiated,
high-purity water.

Univ. of Washington, Seattle, WA, Teaching/Research Assistant 06/1992 to 11/19

96
Held a teaching assistant and research assistant position. Was able to move my
advisors laboratory from pure spectroscopy into the world of chemistry with good
results. Also presented proposals to industrial sponsors and secured funding f
or our group.
Chemist, Progressive Circuit Products, Sacramento, CA 05/1989 to 08/1991
Full service manufacturer of printed circuit boards. Now defunct. Sales ~$4 mi
llion/~50 people
*Developed testing methods for copper, lead, gold, nickel and PTH plating baths
*Hired and supervised a laboratory technician to perform analyses
*Supervised operation of a continuous flow waste treatment system and one operat
or
*Initiated process bath maintenance schedules for reduced chemical usage and dis
posal
*Created systems and methods for bath treatment of high level caustic and heavy
metal wastes
*Researched alternative chemical processes for reduced usage of priority polluta
nts
CSUS, Sacramento, CA, Teaching Assistant 01/1989 to 05/1990
Graded papers, staffed the office help laboratory and mentored students in intro
ductory chemistry.

Aerojet General Corp, Folsom, CA, Laboratory Technician 07/1985 to 08/1988

Aerojet sold military hardware to the US government. They were the leading supp
lier of solid rocket/missile motors.
Performed quality control testing of production line chemicals, polymers and raw
materials.
Analyses performed: Karl Fischer moisture, Kjeldahl nitrogen, hydroxyl content
of fuels, titrations, viscosity, density, microtrac size allotment, sieves, isoc
yante assays.
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EDUCATION
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Ph.D. in Analytical Chemistry, University of Washington, Seattle, WA
"Liquid Chromatographic Separation and Sensing Principles with a Water Only Mobi
le Phase"
Research Advisor: Professor Robert E. Synovec GPA 3.7/4.0
Bachelor of Science in Chemistry, California State University Sacramento, CA
Minor in Physics, California State University Sacramento, CA
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HONORS AND ACTIVITIES
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Organizing Committee HPLC 2006; San Francisco
Program Chair Bay Area Mass Spec. Soc, 2005
Session Chair HPLC sessions; Pittcon, 2002
Associate Director California Separation Science Society (5/2000 to 10/2006)
Session Chair Capillary Chromatography and Electrophoresis Meeting, Park City,
Utah (6/99)
Organizer/Host Chem. and Biochem. Undergraduate Research Symposium (5/95)
President UW Chemistry Graduate Student Organization (10/94 to 10/95)
Senator UW Graduate and Professional Student Senate (9/93 to 9/94)
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PUBLICATIONS
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"A Straightforward Means of Coupling Preparative HPLC and Mass Spectrometry," H.
Cai, .J. P. Kiplinger, W. K. Goetzinger, R. O. Cole, K. A. Laws, M. D. Foster,
A. C. Schrock., Rapid Communications in Mass Spectrometry, 2002, 16, 544.
"Performance of Experimental Sample Injectors for High-Performance Liquid-Chroma
tography Micro-Columns," M. D. Foster, M. A. Arnold, J. A. Nichols and S. R. Bak
alyar, J. Chrom. A, 2000, 869, 231.
"Reversed Phase Liquid Chromatography of Organic Hydrocarbons with Water as the
Mobile Phase," M. D. Foster and R. E. Synovec, Anal. Chem., 1996, 17, 68.
"Liquid Chromatographic Sensing in Water on a Thin-Clad Optical Fiber by Mode Fi
ltered Light Detection," M. D. Foster and R. E. Synovec, Anal. Chem., 1996, 7, 6
8.
"Fiber-Optic-Based Mode-Filtered Light Detection for Small-Volume Chemical Analy
sis," R. E. Synovec, A. W. Sulya, L. W. Burgess, M. D. Foster and C. A. Bruckner
, Anal. Chem., 1995, 473, 67.
"Chemical Sensing of in-situ extracted Organics by Direct Detection of Mode-Filt
ered Light," R. E. Synovec, C. A. Bruckner and M. D. Foster, SPIE Chemical, Bioc
hemical and Environmental Sensors; SPIE: Bellingham, WA, 1994, 166, 2293.
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PRESENTATIONS
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"Rapid, High Resolution Capillary HPLC," M. D. Foster, Cap. Chrom. Electro. Conf
., Riva del Garda, Italy, June, 2004.
"Nanoscale HPLC System for Sensitive Peptide Identification by LC-MS," D. W. Ney
er, J. E. Rehm, M. D. Foster and K. M. Hahnenberger, LC/MS Conference, Savannah,
GA, June 2003
"High Throughput Liquid Chromatography/Mass Spectrometry: Fast Serial Versus Par
allel Analysis," M. D. Foster, Pittcon, 2002.
"Understanding Sample Carryover: The Bane of the High Throughput Laboratory," M.
D. Foster and J. S. Nisenson, Pittcon, 2002.
"An Active Splitter for Interfacing Preparative HPLC to Mass Spectrometry," M.
D. Foster and A. C. Schrock, HPLC Kyoto, Kyoto, JP, 9/12/01.
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PATENTS
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Mass Rate Attenuator. US patent # 6890489