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CL 201- Organic Chemistry

Unit I: Fundamentals of Photochemistry, Qualitative introduction about different transitions, Cis-
Trans isomerization, Paterno-Buchi reaction, Norrish type I and II reactions, photo reduction of
ketones, di-pi-methane rearrangement, photochemistry of arenas .

Unit II: Pericyclic reactions, Classification, electrocyclic ring opening and closure, Cope &
Claisen rearrangement, 2+2 and 4+2 cycloaddition and ene reactions, Woodward-Hoffmann
rules, and FMO theory. Coal Tar distillation separation of aromatics. Theory of orientation in
aromatic electrophilic substitution in benzenoid and heterocyclic compounds.

Unit III: Grignards Reagents, organo lithium compounds formation and reactions in organic
synthesis. Ligand substitution, Oxidative Addition and Reductive Elimination, 1,1 Insertion and
deinsertion reactions, asymmetric hydrogenation, Hydroformylation, Wacker-smidt Synthesis,
Monsanto Acetic Acid and Eastman-Halcon Carbonylation process, Alkene Metathesis, Pd
catalyzed coupling reactions- Heck, Suzuki coupling & Ene Reaction. The Pauson- Khand
Reaction

Unit IV: Identification of organic compounds by using combined Mass, IR and NMR spectral
analysis. Index of hydrogen deficiency. Mass spectroscopy: Methods of desorption and
ionization (EI, CI, MALDI, ESI), study of fragmentation pattern. Basics of IR spectroscopy,
applications. Basic Principles of 1H & 13C NMR, Applications of 1H and 13C NMR (DEPT) to
organic chemistry, Case studies and combined problems

Unit V: Carbohydrates: Structure of ribose, glucose, fructose, sucrose, starch & cellulose and
cyclodextrins, inter conversions of sugars. Dye industry, Synthesis and applications of Azodyes,
Vat dyes, triphenyl methane dyes, Mordant Dyes, Leuco Dyes, Eco Friendly Dyes,
Environmental hazards from dying industry, Waste treatment in dye industry, Oils and Fats,
Analysis.

Text Books:
1. R. R. Carey and R. J. Sundburg, Advanced Organic Chemistry, Part A and Part B, Springer,
5th Edn, 2007
2. Morisson and Boyd- A Text book of Organic Chemistry, 6th Edn, Prentice Hall of India, 1996
3. K. Jagadamba Singh, Jaya Singh, Photochemistry and Pericyclic Reactions, 2nd Edn, New Age
International publications, 2006

References
1. R. M. Silverstein and F. X. Webster: Spectrometric Identification of Organic Compounds, 7th
Edn, 2007
2. R.H. Crabtree, The Organometallic Chemistry of Transition Metals, 4th Edn, Wiley, 2005
3. I. L. Finar. Organic Chemistry, Vol 1 &2, 5th Edn, ELBS, London, 1975
4. K. Hunger, Industrial Dyes, Chemsitry, Properties, Applications, 3rd Edn, Wiely VCH, 2003