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PAPER NAME : MINOR 7

1) Select the suitable match of biosynthetic precursor & its product..

A) Pheny pyruvic acid: Amino acid

B) Ornithine: Ephedrine

C) Ornithine: Atropine

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D) Both a & d

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Correct Answer is D

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2) Select the microscopic character of clothing hair of foxglove

A) Uniserriate, 2-7 celled, blunty pointed warty trichomes

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B) Uniserriate, 2 celled, blunty pointed warty trichomes

C) Uniserriate, unicellular, blunty pointed warty trichomes

D) Uniserriate, 2-15 celled, blunty pointed warty trichomes

Correct Answer is A
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3) The biogenetic precursor of purpureal glycoside is

A) Pregnelonon
ph

B) Ascorbic acid

C) Rehin
.b

D) Emodin

Correct Answer is A
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4) Argel leaf is a substituent of senna & can be distinguished microscopically by

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A) Celluler hairs

B) Bark structure
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C) Stomata

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D) Leaf margins

Correct Answer is A

5) The stereo-configuration of Sennicidine C & D are

A) Trans & Meso

B) Meso & Trans

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C) Trans only

D) Meso only

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Correct Answer is A

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6) Steroidal Drugs are biosynthesized from

A) Diosgenin

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B) Ornithine

C) Pheny pyruvic acid m

D) Tryptophen

Correct Answer is A
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7) Brontrager s Test is not rational for
ph

A) Aloin & Chysaloin

B) Barbaloin & Chysaloin

C) Both
.b

D) None of these
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Correct Answer is C

8) Which one is not a Dianthrone derivative

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A) Sennoside A & B
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B) Sennidin A & B

C) Palmidin

D) None of these
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Correct Answer is B

9) Tautomerism involves

A) Movement of a proton and the shifting of bonding electrons

B) Movement of a proton and electrons

C) Movement of only proton

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D) Movement of only bonding electrons

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Correct Answer is A

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10) Select the complaxant which is used to mask other cations for complexometric titration

A) Triethanolamine & EDTA

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B) EDTA Only

C) Murexide & EDTA

D) Triethanolamine Only

Correct Answer is D
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11) Select the pH independent redox indicator

A) Phenosafranin
ph

B) Thionine

C) Sodium Diphenylamine Sulfonate

.b

D) Sodium 2, 6 Dichlorophenol Indophenol

Correct Answer is C
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12) A acidic drug with acid dissociaotion constant 0.2 is absorbed from stomach. Calculate its
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theoretical log (ionized/unionized) ratio?

A) Zero
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B) Less than 1

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C) More than 1

D) 1

Correct Answer is D

13) Which one is a NMR sample?

A) Protium

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B) Tritium

C) 14N

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D) None of these

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Correct Answer is D

14) Choose the couple of the compounds not give 3 signals in the NMR spectroscopy 1. CH3COOH 2.

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CH3CH2NH2 3. CH3OH 4. CH3CH2CH2Cl

A) 1, 2, 3 m
B) 2, 4

C) 1, 3
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D) 1, 2, 3 & 4
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Correct Answer is C

15) Calculate the NMR peaks of 2,methyl-2-pentene & effect after the attachment of amino group?

A) 6 peaks only with downfield & deshielding

.b

B) 5 peaks & then 6 peaks with downfield & deshielding

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C) 7 peaks & then 5 peaks with downfield & deshielding

D) None of these
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Correct Answer is B
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16) Select the best way to achieve resonance in NMR.

A) Variable radiofrequency

B) Variable magnetic field

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C) Both a & b

D) Variable energy

Correct Answer is B

17) The method of expressing magnetic field strength is&

A) Cycles/sec.

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B) Gauss

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C) Debye units

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D) Gauss/cycle

Correct Answer is B

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18) Select the suitable set about NMR spectra of neopentane.

A) 2 peaks, doublet (1:1) and singlet

B) peaks, all are quintet (1:4:4:6:4:4:1)

C) It is not a NMR sample It is not a NMR sample

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D) None of these

Correct Answer is D
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19) IR range for N-H stretching&

A) 3423 cm-1
.b

B) 3640 cm-1

C) 326cm-1
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D) 2456cm-1
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Correct Answer is A

20) X ray will divert to& ..

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A) Cathode

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B) Anode

C) Not divert

D) divert to both cathode & anode

Correct Answer is C

21) The biosynthetic precursor of quinine is&

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A) Phenylalanine

B) Glycene

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C) Lysine

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D) Tryptophan

Correct Answer is D

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22) Anthraquinone derivatives in glycosides are

A) Bicyclic m
B) Tricyclic linear type

C) Tricyclic angular type

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D) Tetracyclic
ph

Correct Answer is B

23) Isoprenoidal compounds are synthesized from which precursor

A) Erythrose 4 P
.b

B) Acetate
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C) Phenylalanine

D) Fatty acids
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Correct Answer is B
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24) In capsule powder filling, following is the most important characteristics of powder

A) solubility

B) Bulk density
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C) Both

D) None

Correct Answer is B

25) Under Microbial assay I.P. the final pH of the culture media is maintained& .

A) Before Sterilization

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B) After Sterilization

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C) Anytime & not related with sterlisation

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D) No need to adjust the final pH

Correct Answer is B

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26) Bioassay is a procedure for determining the

A) Qualitative relationship between the dose (or concentration) of a drug and magnitude of response

B) Quantitative relationship between the dose (or concentration) of a drug and magnitude of response
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C) Qualitative relationship between the dose (or concentration) of a drug and duration of response
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D) Quantitative relationship between the dose (or concentration) of a drug and duration of response

Correct Answer is A
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27) Following was formerly known as Vagusstoff

A) Noradrenaline
.b

B) Neuropeptide Y

C) Acetylcholine
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D) Adrenaline
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Correct Answer is C

28) Causes Docking and Fusion of synaptic vesicles

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A) Tetrodotoxin

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B) Saxitoxin

C) Neuropeptide Y

D) Syntaxin

Correct Answer is D

29) Is not a example of Co transmitter

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A) Adenosine

B) Enkephalins

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C) Noradrenaline

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D) Somatostatin

Correct Answer is C

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30) Toxin which causes booster release of Ach and then depletion

A) Black widow spinder toxin m

B) Botulinus toxin

C) Tetrodotoxin
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D) Saxitoxin
ph

Correct Answer is A

31) Due to hyperactivity of muscarinic receptor the physiological of a patient is altered what should be

given to antagonize the action

.b

A) Adrenaline
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B) Atropine

C) Bethanechol
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D) Methacholine
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Correct Answer is A

32) Anticholinesterase drug in clinical use/trial for Alzheimer disease is

A) Sarin
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B) Diazinon

C) Galantamine

D) Edrophonium

Correct Answer is D

33) Major neurotransmitter in sympathetic nervous system is

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A) Noradrenaline

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B) Ephedrine

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C) Acetylcholine

D) Adrenaline

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Correct Answer is A

34) Heteroreceptors which causes enhanced NA release

A) Dopaminergic

B) Nicotinic
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C) Serotonergic

D) Muscarinic
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Correct Answer is B

35) Which capsule size is used to dispense 200mg of powder....

.b

A) 0

B) 2
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C) 3
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D) 1

Correct Answer is D
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36) Concerning propellants for metered-dose inhalers, which of the following statements is true?

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A) The vapour pressure remains constant throughout the lifetime

B) The use of chlorofluorocarbons has increased in recent years

C) The volume of propellant released upon actuation is

D) Both a and C

Correct Answer is A

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37) Which one is the correct statement regarding excipients & reasons to include in metered-dose

inhalers?

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A) Ethanol to increase the vapour pressure of the propellant

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B) Tween 80 to enhance the solubility of the therapeutic agent

C) Oleaic acid to stabilise the suspended drug in the propellant

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D) Antioxidants to inhibit oxidative degradation of the

Correct Answer is C m
38) Which is not a true statement regarding soft gelatin capsules?

A) The capsule shell contains glycerol as a plasticising agent

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B) The capsule shell contains approximately 20% water
ph

C) The capsule shell is preferentially composed of type A

D) Both b & c

Correct Answer is D
.b

39) Which of the following is not suitable as liquid fills for hard gelatin capsules?
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A) Polyethylene glycols

B) Purified water
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C) Arachis oil
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D) Fatty acid esters

Correct Answer is B

40) Volatile oils normally extracted using

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A) Decoction

B) Boiling

C) Steam distillation

D) None of above

Correct Answer is C

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41) In nomenclature of fluorinated hydrocarbons the name of dichlorotetrafluoroethane would be :

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A) 12

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B) 14

C) 112

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D) 114

Correct Answer is D

EXP : The nomenclature involves the following principle that is : first digit indicates no of carbon
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atom-1, 2nd digit states for no of hydrogen atoms+1 and third digit denotes the no of fluorine atoms.
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42) Tag open cup apparatus is used to determine:

A) Bloom strength of capsules

ph

B) Vapor pressure of propellents

C) Flash point of aerosol

.b

D) Strength of aerosol container

Correct Answer is C
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43) Particle size of aerosols can be determined by:

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A) Light scatter decay method

B) Coulter counter method

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C) Cascade impactor

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D) Both A and C

Correct Answer is D

44) Diagnostic agent used in diagnosis of myasthenia gravis is:

A) Atropine

B) Edrophonium

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C) Corticosteroids

D) None

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Correct Answer is B

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45) Hepatitis is caused by :

A) Hepatitis A Bacteria

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B) Hepatitis B virus

C) Hepatitis B Bacteria m
D) None

Correct Answer is B
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46) Which of the following is not true about Tuberculosis microorganism
ph

A) It is caused by Mycobacterium tuberculosis

B) The causative organism is a bacilli

C) The organism has unique staining properties (Acid fast) due to the lipid composition of cell wall
.b

D) All are true

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Correct Answer is D

47) IgG immunoglobulins are active against

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A) Viruses
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B) Bacterial toxins

C) Both

D) None
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Correct Answer is C

48) In Cis -Trans isomerism what is the essential requirement?

A) Presence of double bond with asymmetry

B) Presence of a halogen with asymmetry

C) An electron donating group

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D) none of these

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Correct Answer is A

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49) The test organism for microbial assay, are identified according their& .

A) ATCC No. : American Type Culture Collection No.

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B) ATCC No. : Absolute Type Cross Collection No.

C) ATCC No. : Australian Type Culture Collection No.

D) ATCC No. : Aerobic Type Culture Collection No.

Correct Answer is A
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50) Wild cherry bark contains&

A) Cynogenetic glycoside,Prunasin
ph

B) Anthraquinone glycoside, Aloien

C) Isothiocynate glycoside,Silimyrin
.b

D) Cynogenetic glycoside, Silimyrin

Correct Answer is A
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