Investigate the Effect of Small Spot Size and Fluence for Laser Hair

Removal in Lanyu Pigs

Yu-Wei Chiang1
Yao-Chang Liao2

Kai-Jung Chen1
I-Ku Kuo2

Chih-Yen Lin1
Kao-Chi Chung1*

Institute of Biomedical Engineering, National Cheng Kung University

2
Kera Harvest Inc.
*Corresponding Emailkaochi@mail.bme.ncku.edu.tw

(618 mm)

11.52 mm

(A)(B)
808 nm

1 mm40 J/cm2

Abstract
In order to achieve the efficacy of Laser hair
removal, laser system usually adopt a large spot
(Diameter 6~18 mm) for treatment. Although the
treatment time could be reduced, big spot will cause
unnecessary tissue thermal injury near hair follicle.
The purpose of this research is to investigate small
spot size on hair removal (Diameter 11.52 mm).
This research utilizes animal testing (Lanyu pig) to
probe the feasibility of hair removal by small spot
size and laser diode system application. There are
two specific purposes of this research. (A) First, to
design the prototype of small spot size laser diode
system.(B) Second, to design the animal testing of
Lanyu pig. Here we use 808 nm laser source, hand
piece device, and optical mechanism design. Also,
we verify the power, spot size and pulse width. To

apply on animal model and selection treatment parts

by the leading experimental data , the layer thickness
of porcine abdominal skin , hair structure , are
similar to human. We confirmed that Lanyu pig is
the appropriate animal model for laser hair removal.
We did a section and staining for tissue of pig skin.
The results show that when conditions are within 1
mm spot size, fluence 40 J/cm2, there is some outer
root damage, hair shaft structural disintegration, the
hair follicles swelling around, and the vacuoles
presenting within the hair shaft after injection.
Therefore, we prove that small spot size laser has the
feasibility on hair removal; it could be a new
treatment of laser hair removal.
Keywords: Laser Hair Removal, Spot Size,
Lanyu Pig.

( 618 mm)

11.52 mm

A
B
A.
(a)
(b)(c)

(a)
808 nm20 W
(200 mN.A.0.22
SMA 905 )
6V/20A
RS232(
)

mm

ho

1mm
1.5mm
2mm

40
30
20

48
34
22

240
255
220

40
30
20

6.75
4.78
3.09

17.79
40.02
71.15

5
7.5
10

() p
5.
4. q
4.2. 1

11.52
mm

1
1
2
1
3
(M3-4)
4

(Y49-481)
5

6
2
7
(MSV2_6)
8

(SM05SMA)
9
3
10

(b)

f D
a O p() O
b q( )
o
a
hop tan(o) ()
o8
200m

11.52 mm M 57.510

(a)

(b)

(a)(b)
(c)

29 A
5
Y aX
b

11.52 mm

10203040506070 ms
5

N-SF11
(0.7
@7501550 nm)

B.
()
()
() ()

()

III.
()

()

(a)

(a)

(b)

(b)

(c)

(c)

(d)

(d)

(e)

(e)

(f)

(f)

(g)

(g)

()

I.

(Arrector pili muscle)(Sweat glands)

(Collagen fibers)(Elastic fibers)
(Medulla)
(Cortex)(Internal root sheath)
(Outer root sheath)[24]

()

(Biopsy punch)

() [3]
II.

618 mm 10
50 J/cm2 1
1.52 mm203040 J/cm2
[4]

(h)

()
()

(A)
(a)
y =
2.3901x - 4.5128 R = 0.99

(W )

50120 m 30140
m 10 : 1
13 : 1[24]

()

()

20
18
16
14
12
10
8
6
4
2
0

(W)

y = 2.5696x - 4.6167
R= 0.997

10

(A)

(b) ()(
= 0.8321= 0.863mm)()
(= 1.421mm= 1.382()
(= 1.926= 1.954mm)

()
1 mm
40 J/cm2

(HE )
(a) (b) 1 mm 40 J/cm2

(c)

ms

Mean SD

[1]

10
20
30
40
50
60
70

10.0 10.0
20.0 19.8
30.0 30.0
40.0 40.2
50.0 49.8
60.0 60.0
70.0 69.8

10.2
20.0
29.8
40.0
50.0
60.2
70.2

10.2
19.8
30.2
39.8
50.1
59.8
70.0

9.8
20.0
30.0
40.2
50.2
60.1
70.0

10.04
19.92
30.00
40.04
50.02
60.02
70.00

0.17
0.11
0.14
0.17
0.15
0.15
0.14

(B)
()

()

(HE )
(A)(B)
()

[2]
[3]

[4]

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Regeneration , 9:66-76.
Nina Otberg, Heike Richter, Hans Schaefer, Ulrike
Blume-Peytavi, Wolfram Sterry, and Jrgen
Lademann (2004) The Journal of Investigative
Dermatology,122:14-19.
Lin. TY, Manuskiatti W, Dierickx C.C., Farinelli
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(DY-01-01-04-98)