Name Generic Name Cefuroxime Trade Name Ceftin Classification: Antibiotic, anti-infectivend 2 generation cephalosporin

Indication Pharyngitis, tonsillitis caused by S. pyogenes Otitis media caused by S. pneumoniae, H. influenzae, M. catarrhalis, S. pyogenes Lower respiratory tract infections caused by S. pneumoniae, H. parainfluenzae, H. influenzae

Mechanism Of Action Binds to one or more of the penicillin binding proteins (PBP located on cell walls of susceptible organism, inhibiting 3rd and final stage of bacterial cell wall synthesis and thus killing the bacterium

Contraindication Hypersensitivity to cephalosporins and related antibiotics; pregnancy, lactation

Interaction Drug interactions Probenecid = decreases renal elimination of cefuroxime, prolonging its action

Side Effects CNS: Headache, dizziness, lethargy, paresthesias GI: Nausea, vomiting, diarrhea, anorexia, abdominal pain, flatulence, pseudomembranous colitis, liver toxicity GU: Nephrotoxicity Hematologic: Bone marrow depression: decreased WBC, decreased platelets, decreased Hct

Adverse Reaction Hypersensitivity: Ranging from rash to fever to anaphylaxis, serum sickness reaction Local: Pain, abscess at injection site; phlebitis, inflammation at IV site Other: Superinfections, disulfiram-like reaction with alcohol

Nursing Responsibilities Advise patient to report severe diarrhea, difficulty of breathing, unusual tiredness of fatigue Report if there s pain at injection site.(redness,swelling) Advise patient to avoid alcohol while on this drug and for three days after. Warn patient that this drug should not be used to self-treat

Generic Name: Paracetamol Trade name: Biogesic Classification: Anti-pyretic

Symptomatic relief of pain and fever.

Inhibits prostaglandin biosynthesis in the central nervous system but not (or hardly) in the peripheral tissues. Paracetamol only has

Contraindicated in patients hypersensitive to drug. Use cautiously in patients with long term alcohol use because therapeutic doses cause hepatotoxicity in these patients.

Drug Interactions: Barbiturates, Carbamazepine, Hydantoins, Rifampin may reduce therapeutics and may enhance hepatotoxic effects of acetaminophen.

Rash, blood disorders, hypotension (low blood pressure) when given by injection into the vein (in hospital), liver and kidney damage - when taken at higher than recommended doses.

Hemolytic anemia, neutropenia, leucopenia, pancytopenia Jaundice, hypoglycemia

Advise patient that drug is only for short term use and to consult the physician if giving to children for longer than 5 days or adults for longer than 10 days. Advise patient or caregiver that many over the counter products contain acetaminophen; be aware of this when

minimal antiinflammatory action compared to non-steroidal antiinflammatory agents. Generic Name: Ciprofloxacin Brand Name: Quinosyn Classification: Antibacterial Ciprofloxacin is used to treat infections of the skin, lungs, airways, bones, and joints caused by susceptible bacteria. Inhibition of topoisomerase (DNA gyrase) enzymes, which inhibits relaxation of supercoiled DNA and promotes breakage of double stranded DNA. Contraindicated in persons with a history of hypersensitivity to ciprofloxacin, any member of the quinolone class of antimicrobial agents, or any of the product components.

Drug-food interaction: Caffeine may enhance analgesic effects of acetaminophen. Drug interaction: Aluminum hydroxide, calcium carbonate and drugs containing zinc may decrease ciprofloxacin effects and absorption

calculating total daily dose. Warn patient that high doses or unsupervised long term use can cause liver damage.

Nausea, Vomiting, Stomach pain, Heartburn, Diarrhea, Feeling an urgent need to urinate, Headache, Hives, Difficulty breathing or swallowing, Hoarseness or throat tightness, Rapid, irregular, or pounding heartbeat, Fainting, Fever

Seizure Hallucinations Nephritis, Crystalluria Pseudomembrane colitis

Instruct patient not to take ciprofloxacin with dairy products such as milk or yogurt, or with calcium-fortified juice. may eat or drink dairy products or calciumfortified juice with a regular meal, but do not use them alone when taking ciprofloxacin. They could make the medication less effective. Inform that Ciprofloxacin may cause swelling or tearing of a tendon (the fiber that connects bones to muscles in the body), especially in the Achilles' tendon of the heel. Take medication with food.

Generic Name: Loratadine Brand Name: Claritin

Relief of symptoms of atopic dermatitis, angioedema, urticaria,

Loratadine is a potent longacting tricyclic antihistamine with selective peripheral H1-

Contraindicated to patients with hypersensivity to drug Use cautiously in

Drug interaction: By using loratadinebetamethasone

Fatigue, headache, somnolence, nervousness, dry mouth, GI disorders (eg nausea, gastritis) & allergic symptoms

Insomnia

Classification: Antihistamine

seasonal & perennial allergic rhinitis, food & drug allergic reaction.

receptor antagonistic activity.

patients with hepatic or renal impairment

in combination, tablets combine the antiinflammatory and antiallergic effect of the corticosteroid (betamethasone) with the nonsedating antihistamine

eg rash.