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Mechanism of Action
Indication
Contraindication
Adverse Reaction Ataxia, drowsiness, fatigue, psychosis, syncope, vertigo, headache, worsening of seizures
Nursing Precaution
Unclear. Chemically related to tricyclic depressants (TCAs). Anticonvulsant action may result from reduction in polysynaptic responses and blocking of post-tetanic potentiation.
Hypersensitivity to drug or TCAs. MAOI use within past 14 days. Bone marrow depression Pregnancy or breastfeeding
200mg/tab 1/2
Unknown. May block postsynaptic dopamine receptors in brain and depress areas involved in wakefulness and adrenergic-blocking properties. Thought to work by affecting the activity of a natural compound called dopamine in the brain. Dopamine is known as a neurotransmitter, and is involved in transmitting messages between brain cells. It is known to be involved in regulating
Sedation, drowsiness, extrapyramidal reactions, tardive dyskinesia, pseudoparkinso nism, seizures Pregnancy and lactation CNS depression Liver damage Renal dysfunction
Monitor patient closely Assess for history of psychosis; drug may activate symptoms Monitor baseline hematologic, kidney, and liver function test results. Assess for extrapyramidal symtoms.
20mg/amp IM
Maintenance therapy for chronic schizophrenia in patients whose main manifestations do not include excitement, agitation, or
mood and behaviour, amongst other things. Unlike other antidepressants, flupentixol usually starts to produce an antidepressant effect within two to three days. However, it may not make you feel fully better for at least few weeks. Biperiden Hydrochloride 2mg/tab BID PRN for EPS Anticholinergic activity in the CNS that is believed to help normalize the hypothesized
hyperactivity
Hypersensitivity to benetropine Glaucoma, stenosing peptic ulcers Bladder neck obstruction Pregnancy and lactation Alzheimers disease
Disorientation, confusion, memory loss, hallucinations, nervousness, light headedness, dizziness, blurred vision, dry mouth, constipation, flushing, urinary retention