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Koriesh’s Extract of Microbiological Arts

Gram + cocci

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

Organism

Gram

ChCh

Virulance

Disease

TTT

Staph aureus

G+ cocci

Catalase +, coagulase +, B heam. ferment manitol, yellow clusters flora in ant. Nares.

TSST, Exfoliatins(SSS), Cytolysins(pores) , ptn A(antiphag bind to

Pdf: IV drug abuse, CGD

Methicillin

IE, osteomyelitis (mcc except in sickle) , abcess, impetigo,SSS

MRSA

IgG Fc portion at C Binding site to dec C

Vancom.,

 

activation ), enterotoxin, coagulase

fusidic a.

Staph epidermidis

G+ cocci

Catalse +, coagulase -, no heam., novobiocin sens.

 

IE (in iv drug abusers usually in Rt side of i heart)

Usually

Methicillin resis.

Staph

G+ cocci

Catalse +, coagulase -, no heam., novobiocin resis.

 

UTI

 

saprophyticus

Strept Pyogens GAS

G+ cocci

Catalase -, B heam., pyr +, chains Bacitracin sens.

Subtyped acc. To ptn M cause hyalurunic caps. Is not immunogen.

Hyalurunic a. Capsule, ptn M (antiphag),

Pharyngitis,impetigo,Scarlet fever

B lactams or Erythromycine

streptolysin O: heamolysis, immungenic streptolysin S: heamolysis,not imungen

Exotoxin A-C: superAg, dec. Liver clearance of normal flora,fever&rash of scarlet fever

RF: (pharyngitis- type II) AGN: (pharyn. Or impetigo by m12- type III) ASOT > 200 = significant

Strept Agalaciae GBS

G+ cocci

Catalase -, B heam., camp +, Bacitracin resis.

 

Pdf:present in vaginainfect newborn esp in PROM

Ampicillin +

gentamycine

   

Neonatal Meningitis (MCC),

Intrapartum pen

Strept Viridans (mutans+sanguis) Not gropable

G+ cocci

Catalse -, α heam., bile resis., optochin resist

Biofilm to adher to tooth or damaged Ht valve by making insol. Dextrans from glucoseadher to fibrin pltlt aggreg. valve veget.

IE (after dental work) , Dental caries

Penicillin G + gentamycine

AB befre dental work

Strept Pneumonia Not gropable

G+ cocci

Catalse -, α heam., bile sens., optochin sens. D shaped dipplococci

IgA protease teichoic a. pneumolysin O Polysach. Capsuleswelling e antisera (Quelling t.) , can be acq. by chrom.l uptake from media e virulent strain

PneumoniaMCC of bact

 

pneumonia

MeningitisMCC in adults

   

O.MMCC in children Pdf:asplenia,alcohol,CHF, COPD

Enterococcus

G+ cocci

Catalse -, var heam., pyr + Grow in 6.5% NaCl (also staph &

 

IE (after genitourinary procedure) UTI

Resist

fecalis

vancomycine by

GDS

vibrio paraheam. Grow in 6.5 NaCl)

using Dalanyl Dlactate instead of D alanyl D alanin

Strept bovis

G+ cocci

Catalse -, var heam. No growth in 6.5% NaCl

 

IE (in patient e coloncancer)

 

GDS

Heamolysis:Gamma(none)α(partial green heamolysis) β (complete)

Strept is classified by Lancfield acc to cell wall carbohydrates

Koriesh’s Extract of Microbiological Arts

Gram + Rods

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

Organism

Gram

ChCh

Virulance

Disease

TTT

Bacillus

G

+ rods

Aerobic - Sporingexotoxin - not motile (most other bacilli r motile)

Polypeptide capimmunogenic, antiphago.

Cut. Anthrax

Ciprofloxacin

Anthracis

 

Anthrax toxin: LF(kill cells)-EF(adenyl

Pulm. Anthrax

Doxycycline

 

cyclase)- protecting Ag

Bacillus

G

+ rods

 

Emetic toxin(rice) Diarrheal toxin(meat)

Food poisoning

 

Cereus

 

Listeria

G

+ rods

Aerobic - non sporing motile no toxins Intracellularprblm in IC

Listeriolysin Oescape pf phagosomes Jet(tumbling) motilitymove to cytosol of other cells

Listeriosis: healtyasymp. Pregcross placentafetal dis.

Ampicillin +

 

gentamycine

in uterogranulomatosis infantsepticum

Cold growth in soft cheeseavoid in pregnancy

 

After birthmeningitis In IC meningitis (MCC in IC)

Cornybacterium

G

+ rods

Aerobic non sporing non motile

Diphteria toxindec. Ptn synthesis(EF2) (coded by phagecan be transmitted)

Diphteria: psaudomemb. myocarditis RLN palsy

Erythromycine

Diphteria

 

exotoxins -V&L shapeschinese letters

+ antitoxin

Polar metachrom. gran. stain e anilin Loffler serum(S) Tollerete agar(D)

Elik test: to document toxin prod: strip of org. On paper e antitoxinprecipitate line

 

Nocardia

G

+ rods

Aerobic - Partialy acid fast

No virulance By implantation or dust inhalation In IC & cancer patients

Nocardiosis: cutabcess Pulmgoto brainabcess

Cotrimoxazole

asteroids

 

Actinomyces

G

+ rods

Anerobic

Invasive growth in tissues e poor O 2 supp.

Actinomycosis: invasive dis.--> abcesses e sulpher granules.

Penicillin +

israeli

 

drainage

Clostridium

G

+ rods

Anerobic sporing exotoxins motile

Tetanus toxin: “tetanospasmin” Carried intra axonal to CNSblock GABA releasems spasm

Tetanus: opisthotonus, risus sardonicus Implant. From soil in wound

IG + Vaccine Depriment Penicillin or flagyl Diazepam

tetani

 

Clostridium

G

+ rods

Anerobic sporing exotoxins - motile

Botulinum toxin: heat labile neurotoxin coded by prophage-absorbed from gut to priph. nsblock A.Ch release at NM juncflacid paral.

Botulism:

 

botulinum

 

Flaccid paral. e diplopia, dysphagia, resp. Paral.

Clostridium

G

+ rods

Anerobic sporing exotoxins

Alph toxin: lecithinase(dmg

Gas gangrene:wound e soil or feacespain, edema,exudat Food poisoning

Depriment &

perfringens

 

Not motile(the only clostridia that not motile)

phospholipids)heamolysis, cytolysis Negler reaction: egg yolk plate e side e antitox. & side e outtoxin activity on side e no antitoxin

Enterotoxinwatery diarrhea, cramps

Delayed closure

Double heamolysis Lecithinas producer: detected by

Clindam. +

penicilline

 

Hyperbaric ch.

Clostridium

G

+ rods

Anerobicsporingexotoxins-motile norm colon flora prod dis. only when other flora(biomass) lost by AB use.

Toxin A: enterotoxin dmg mucosa Toxin B: cytotoxindmg cytoskel. by actin depolymerization.

AB ass. psaudomemb. Colitis & Diarrhea (penicillin-Cephalosporin- clindamycine)

Metronidazole

deficile

 

Koriesh’s Extract of Microbiological Arts

Wound managment of tetanus:

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

 

Not tetanus prone

Tetanus prone

Linear no dead tissue no contamination e in 6 hours

Blunt dead tissue contamination any wound > 6 hs

Not completed 1ry vaccination

Vaccine

Vaccine + TIG

completed

Vaccine if booster < 10 years

Vaccine if < 5 years

Forms of Botulism:

 

Food borne

Wound

Infant

Aquisition

Preformed toxin ingestion in smoked flish & canned vegetables

Traumatic implantation of spores

Spores ingested in honey & dust Toxin produced in gut

Symptoms

Weakness, flaccid paral (reversible), NVD

Same e no NVD

Constipation, flacid paral (reversible), diplopia, dysphagia, resp. Arrest

Toxin present in

Serum & Food

Serum

Serum & Stool

Prevention

Heating all canned food

No honey in 1 st year

TTT

Polyvalent antitoxin No AB because toxin is already performed Resp. support

Polyvalent antitoxin Amoxicillin Resp. Support

Hyper immune human IG No AB worsen the dis. Resp. Support

+ Mycobacterium

Koriesh’s Extract of Microbiological Arts

Gram Aerobes

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

Organism

Gram

ChCh

Virulance

 

Disease

TTT

N.

G

- cocci

Oxidase + , ferment maltose, kidney diplococci Choclate agar Nasopharynxdroplet infbloodmeninges

Capsule pili Ig A protease endotoxins(lipo-oligosacharide)

Meningitis Water house fridrichson synd:DIC + shock + meningitis

Penicillin G - Ceftriaxone

meningitidis

 

Prev:Vaccine to risk rifampicine to contacts

N.

G

- cocci

Oxidase + ,not ferm. maltose, kidney diplococci thyer martin (vancomycin,nystatin,polymixin) Genital tractSTD, at birth

No capsule pili Ig A protease invade mucosainflam.

 

Gonorrhea: urithritis, cervicitis, PID

Ceftriaxone +

gonorrhea

 

tetracycline (for clamydia)

B

lactamase

 

Prev:Silver nitrate 4 newborn

Moraxella

G

- cocci

Diplococci

B lactamase

   

OM , bronchopneumonia

 

cataralis

     

Pseudomonas

G

- rods

Oxidase + , not ferment on maconkey ,catalase + Pyocyanin blue green pig.blue green pus, grap like odor In water aerosols & raw vegetables

Capsule endotoxin Exotoxin: dec ptn synthesis (EF2) mainly affect liver

 

Healthy: no symp folliculitis Burn ptn: mig. frm gut to burn CGD & asthma: pneumonia Catheter: UTI CF: rec. Pneumonia IC: Ecthyma gangonosum

Antipseudomonal pen. 3 rd gen cephalosporins Prevention:

aerogenosa

 

(target shaped necrotic lesions e black center)

(target shaped necrotic lesions e black center)

Disinfic. Of water equip. No flowers or veget. In burn units

Legionelle

G

- rods

Req iron & cysteine , CYE media , fac. Intracellular In air conditioning no human to human transmission

Endotoxin intracellular Diag by legionella Ag in urine (diffic. To find bacteria in sputum by gram stain)

 

Legionairs dis:

Fluroquinolon ICerythromycine + rifampicine

Prev:decont. Air conditioning

pneumophilia

 

Atypical pneum. mental confusion diarrhea Pontiac fever: pneumonitis

Boordetelle

G

- rods

Strict aerobe , regan lwe or bordet gengu media In human throat

Adenyl cyclase toxin edema

Wooping coughlifelong immunity

Erythromycine

pertussis

 

Pertussis toxin: ADP ribosyl. Of

Prevention:

 

G

i lymphocytosis, block

20% of adults e cough e out fever > 2 weeks have pertussis

Dtap vaccine7 ys

 

immune cells, hypoglycemia

Francesella

G

- rods

Intracellular facult. In wild andimals esp. Rabbits & rodents

Granulomatous response, intracellular

 

Tickulceroglandular dis Traumatic imp.: ulcerogland dis

Aerosol(skinning rabbits): pneumonia

Streptomycine Gloves while butchering rabbits Vaccine 4 high risk

tuleransis

 
     

Ingestion: typhoid tuleremia

Brucella

G

- rods

Intracellular facult. zonotic In domestic animals (by contact or dairy products)

Endotoxin, intracellular, granulomatous response

   

Brucellosis(undulant fever)

Prevention:

 

B.

abortus: cattle

Vaccine cattle

 

B.

suis: pigs

Pasteurize milk

 

B.

meltinesis: goats

Campylobac

ter jejuni

G

Motile curvedflagellaCampy or skirrow media

Invade mucosa, law infec. Dose

 

Diarhea e pus & blood (MCC in US) Self limited to 3:5 days Complic.: GBS guilan bare

Erythromycine

Helical

In intestine of humans & poultry feco-oral

Fluroquinolones

rods

Can be transmited from domestic animals

Helicobacter

G

Motile spiral flagellacampy or skirrow media

Urease + amonianeutralize acids

 

Gastritis DU cancer stomach

Omeprazole +

pylori

Helical

In humans feco-oral

Mucinaseinvade mucus Invade mucousa

 

Breath test:

amoxicilline+

rods

C 131 ureaCO 2 131 - serology

clarithromycine

Koriesh’s Extract of Microbiological Arts

Gram Enterobacteriacea

Gram ve rods , facult. Anearobes , catalase +ve , oxidase ve(all other G ve are Oxidase +) , ferment glucose, differ in lactose (determind on macConkey) CEEK ferment (Citrobacter, Ecoli, Enterobacter, Klebsiella colored colony) , SHYPS not ferment (Shigella, Yersenia, Proteus, Salmonella colorless)

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

Organism

Lactose

ChCh

Reservoir

Virulance

Disease

TTT

Ferm.

Klebsiella

+ve

Large capsule

Human colon, resp. tract

Capsule endotoxins

Pneumonia e abcess & thick bloody sputum “current jelly” esp in DM&alcoholic - UTI

AB sens. T.

pneumonia

Echerichia coli

+ve

All ferment sorbitol except EHEC Reduce nitrate to nitrite Motile capsulated (K1 Ag) B heamolytic EMB "eosin methylin blue agar"blue black colonies metallic sheen

Human colon EHEC: bovine feaces (undercooked beef)

ETEC: LT:heat labile, stim. Adenyl cyc. Cholera like toxin ST:heat stable, stim. Guanyl cyc Traveller’s diarrhea

ETEC : LT:heat labile, stim. Adenyl cyc. Cholera like toxin ST:heat stable, stim. Guanyl cyc 
 

Green

Rehyd.&cotrimoxazole

colony

EPEC: Infantile diarrhea (2 nd MCC after rotaavirus)

 

adher. F. Adher to mucosablunting of brush border

EIEC: invade mucosa Watery diarrhea, fever, WBCs in stool

EIEC : invade mucosa  Watery diarrhea, fever, WBCs in stool

Fluroquinolones

EHEC: VTEC Verotoxin prod. Ecoli No fever, HUS e AB use Verotoxin: shiga like toxin dec. Ptn synth.Not invasiveno fever EaggEC: fimbriabrick like stocking on epithPersis. Diarrhea, UTI

dec. Ptn synth.Not invasive  no fever EaggEC : fimbria  brick like stocking on epith

no AB

 

-Neonatal meningitis (2 nd MCC after GBS) UTI - Cystitis

-Neonatal meningitis (2 n d MCC after GBS) – UTI - Cystitis

cotrimoxazole

Shigella

-ve

Not motile , not H 2 S prod. Resist acid & bilevery law infective dose as low as 10

Human colon only

Invade mucosa (most imp. Pathogen. Fact.)shallow ulcers Shiga toxin: dec ptn synth(inh. 60 S)

Shigellosis enterocolitis High fever, bloody diarrhea, shallow ulcers

Rehyd. + AB

Yersenia

-ve

Not motile , not H 2 S prod. Bipolar stain coagulase +

Rodentflea bite Resp droplet

 

Bubonic plague: by Rodent flea bite Pneumonic plague Inh. From inf. Person or emboli from bub.

Tetracyclin + streptomycine + 3 days quarantine

pestis

Yersenia

-ve

 

Milk&pork (zonotic)

 

Enterocolitis & pseudo appendicitis

Prev.: killed vaccine

enterocolitica

Proteus

-ve

Motile e flagella , H 2 S prod., urease prod. Proteus Ag cross react e ricketsia in weil fleix T.

Human colon Soil & water

Urease alk. Urinestaghorn stone

UTI e stone formation

AB sens. T.

Salmonella

-ve

Motile , H 2 S prod.

Human colon only Feco oral from GB carrier

Infec. Begin in ileocecal regionreach basal border of M cellsmesentric LNBlood (+ in 1 st week) GBstoolstool (+ by 3 rd week) Survive intracel. & when released escape complement by Vi capsule Ag

Typhoid fever “enteric fever” D: Widal test.

Ciprofloxacin,

Ceftriaxone

typhi

   

Vaccine:3 types Oral attenuated, Parent. Killed,Parent. Polysach. Caps.

Salmonella

-ve

Motile, H 2 S prod.

Human & domestic animals Raw chicken products

Invade mucosa inflam. diarrhea

Gastroenteritis ( 2 nd MCC after campylobacter)

If severe AB sens.

typhimurium,

enteritidis

T.

Osteomyelitis (MCC in sickle dis. not trait) d.t. defec. monocyte func.

   

Koriesh’s Extract of Microbiological Arts

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

Vibrio cholera

G-ve

Curved Motile, inactivated by antisera Grow on TCBS and alkaline media (Very sens to gastric acidityinfec. dose e omeprazole )

 

Cholera enterotoxininc. Adenyl

Cholera: rice water stool

Rehyd. + doxycycline Prev: vaccine + doxycyc.

rods

Human colon Contaminate shellfish

cyclaseinc. CAMPefflux of Cl - , H 2 O

Pasterulla

G-ve

 

Mouth of cats & dogs

 

Cat bitecellulitis

Emox/Clav.

multocida

rods

Bacteroides

G-ve

Anearobic

Predominant colonic bact.

Modified LPSendotoxin e reduced activity

Peritonitis , septicemia

Metronidazole,

fragilis

rods

clindamycine

Heamophilus

G-ve

Req factor X(hemin),V(NAD) not present on blood agar but present on choclate. Grow on blood agar seede e staph aureus w release heamin

Nasopharynx

Polysach. Capsule , Ig A protease Vaccine only against Hib so vaccinated can still get O.M, bronchitis by non capsulated or other strain then B

Meningitis: in unvaccin. Children 3m:2ys (MCC) Epiglottitis (MCC) OM - pneumonia

Ceftriaxone &check throat before discharge if still + rifampicin Prev: Capsul. Vaccine+ rifampicin to contacts

influenza

rods

Ag: O= cell envelop

H=flagellum

K=capsule

Vi=salmonella capsule

Vibrio paraheamolyticus: in undercooked sea foods food poisoning

Vibrio vulnificus: in brakish waterwoundcellulitis

ingestedGE

Bacteroides melaningicus: melanin prod. (black) normal gingival flora

Heamophilus ducrei: STD chancroid “soft painful chancre” do cry of pain

Ureaplasma urealyticum : genital floraurethritis req special media rich in urea & cholesterol ttt as Chlamydia by doxyclin or azithromycin

Koriesh’s Extract of Microbiological Arts

Spirochetes (spiral e axial endoflagellum poor Gram stain but G-ve)

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

Organism

ChCh

Reservoir

Disease

Lab

TTT

Treponema pallidum

Not

Human genital t.--> STD Or Cross placenta

Syphilis:

Dark field or immunoflorscence Non treponemal Ag T.:

Benzathine

cultured

1 ry chancre 2 ry macculopap. Rash including palm&sole Condyloma accuminata “perianal wart like” 3 ry Gumma Cong.--> notched tooth, 8 th n. Palsy, keratitis

penicillin

 

“using cardiolipin of cows Ht” Very sens. But not specific, confirm by FTA-ABS VDRL-RPR-ART Treponem Ag T.: “specific”

Jerish Heximer reaction: inc temp, dec BP in 1 st day of ttt

FTA-ABS: florsc. trepon. Ab abs. t. TORCH no longer cont. syphilis, you must order separatly

Borrelia burgdorferi

 

White footed mouseby nymph White tailed deerby tick

Lyme dis. :

Ampilifiacation probe Serodiag. Kelly media

 

erythema migrans: annular skin lesions Fever, headache, malaise Lamphadenopathy Latermeningitis, Bell’s palsy, myocarditis, pericarditis ,arthritis

1 st Doxycyclin 2 nd -> Ceftriaxone

Avoid tick bite Vaccine to risky

Leptospira interrogans

Terminal

In urine&feces of animals

Leptospirosis: influenza like dishepatitis, RF

Dark field microscopy, Serodiag. Fletcher media

Doxycyline&Vaccine of animals & pets

hook

jet skinners-sewe workers

Ricketsia : obligate intracellular, cant make enough ATP, not seen e Gram (too small) but have G-ve wall

Disease

Bacterium

Vector

Reservoir

C.P.

Diag

TTT

Rocky mountain

Ricketsia ricketsii

Ticks

Dogs, rodents, tichs

Fever,malaise,ankle&wrist swilling Rash maculopapular then petichal start on wrist&ankle then to trunk

Symp foll. Tick bite

Doxycyclin

spotted fever

Weil flix T.

Q Fever

Coxiella burnetti

none

Cattle, sheep, goats

Fever e no rash Pneumonia, hepatitis

 

Doxycyclin

By inhal. Of urine&stool aerosol

Vaccine to high risk

Ehrilichosis

Ehrilica

Ixodes

Ticks

Like rocky mountain e out rash Infect monocytes or granulocytes

   

ticks

Cat scratch disease

Bartonella hansele

None

Cats

Cause also Bacillary angiomatosis in IC (red popular skin lesions)

   

Epidemic Typhus

R.

prowazekii

louse

Humans

     

Endemic Typhus

R.

Typhi

Flea

Rodents

     

Scrub Typhus

R.

tsutsu gamoshi

mites

rodents

     

Koriesh’s Extract of Microbiological Arts

(Drkoriesh@yahoo.com)

ةيجولويبوركيملا نونفلا يف ةيشيرقلا ةصلاخلا

Organism

ChCh

Reservoir

Disease

TTT

Malassezia furfur

Spagetti&meat balls : yeast clusters & short curved hyphea

Skin flora

Pityriasis versicolor Fungemia in prematures

balls : yeast clusters & short curved hyphea Skin flora Pityriasis versicolor Fungemia in prematures Topical

Topical selenium

sulphide

Dermatophytes

Hyphea e arthroconidia Microsporumwood’s lamp

Humans &

Tinea capitis, cruris, corporis, barba(beard), pedis, favus

Trichophytonskin, hair, nail Microsporumskin, hair Epidermophytonskin, nail

Topical&systemic imidazoles,Grisof ulvin, Keep dry

animals

Sporotrix

schenkii

Env formhyphea e rosttes&sleeves of conidia Tissue formCigar shaped yeast

On plant

material “rose

thorns”

Sporotrichosis: “rose gardener dis.”subcut. Lesion Pulmonary sporotrichosis:”alcoholic rose gardener sleeper dis” in homeless alcoholics

sporotrichosis:”alcoholic rose gardener sleepe r dis”  in homeless alcoholics Itrakonazole KI in milk
sporotrichosis:”alcoholic rose gardener sleepe r dis”  in homeless alcoholics Itrakonazole KI in milk

Itrakonazole

KI in milk

Histoplasma

Env formhyphea e tubercle macroconidi&microconidia Tissie formsmall intracel. Yeast e no capsule, fac. IC in RES cells (misssesebi & ohaio river valley)

Soil e bird or bat feces in cave explorers&chi cken cleaners

Fungus flavus: self resolving pneumonia e flue like symp + HSM In summer, in kids & new comers Dissim. Mucocut. Lesions & meningitis in AIDS Calcify after healing

summer, in kids & new comers Dissim . Mucocut. Lesions & meningitis in AIDS Calcify after
summer, in kids & new comers Dissim . Mucocut. Lesions & meningitis in AIDS Calcify after

Amphotricin B

capsulatum

“no capsule”

Coccidoids

Envhyphea e arthrocon. Tissuespherules&endospores (arisona,California,new mixico) After earth quakes

Desert sand

Valley fever: self resolving pneumonia, dissim. In 3 rd trimester of preg. Dissim. Mucocut. Lesions & meningitis in AIDS Calcify after healing

In 3 r d trimester of preg. Dissim. Mucocut. Lesions & meningitis in AIDS Calcify after

Amphotricin B

immitis

Blastomyces

Envhyphea e non descript conidia

Rotting wood

Blastomycosis: non self resolving pulm. dis. So ttt even acute cases e ketoconazole Can infect immunocompetent host.

: non self resolving pulm. dis. So ttt even acute cases e ketoconazole Can infect immunocompetent
: non self resolving pulm. dis. So ttt even acute cases e ketoconazole Can infect immunocompetent

Ketoconazole

dermatidis

Tissuebudding yeast e dbl refractile wall (central America )

Aspergillius

Filamentous branching e acute angles

Moldy

Allergic bronchopulm. Aspergillosison mucus Fungus ball(in preformed cavity) surg. Removal to dec. cough & hge Invasive aspergillosisin CGD, CF, burnscellulitis,pneumonia,meningitis

Removal to dec. cough & hge Invasive aspergillosis  in CGD, CF, burns  cellulitis,pneumonia,meningitis AMB

AMB or

marijuana

itrakonazole

fumigatus

 

Pits

Candida

Envyeast Tissuehyphea&pseudohyphea Serumbudding yeast

 

Oral thruch esophagitis gastritis septicemia - endocarditis vaginitis (pdp f:G+ve bactobacilli in vaginaPHdmg normal flora)

– vaginitis (pdp f: ↓ G+ve bactobacilli in vagina  ↑ PH  dmg normal flora)

Topical imidazole,

albicans

nystatin

DesimAMB

Cryptococcus

Encapsulated yeast: Detect capsule Ag by latex

Soil e pigeon

Meningitisin AIDS, hodgkin Pulm. infecin pigeon breeders

e pigeon Meningitis  in AIDS, hodgkin Pulm. infec  in pigeon breeders AMB + 5FU
e pigeon Meningitis  in AIDS, hodgkin Pulm. infec  in pigeon breeders AMB + 5FU

AMB + 5FU till afebrile then fluconazole

neoformans

dripings

India inkbudding yeast e caps halo

 

Mucur

Broad non septate hypha e 90® branches

Soil

Rhinocerebral infecpara nasal swelling, hgic exudate from nose& eye Very invasive esp in DKA & Leukemia

infec  para nasal swelling, hgic exudate from nose& eye Very invasive esp in DKA &

Debride necrotic

Rhizopus, absidia

tissue

 

AMB

Pneumocystitis

Silver stained cysts in tissue Oblig. Extracellular

 

Pneumonia (in AIDS, premature) Serum leak in alveoliexudateFoamy honey comb appearance “cysts in the exudate cause spaces”

Serum leak in alveoli  exudate  Foamy honey comb appearance “cysts in the exudate cause

Cotrimoxazole

carinii