ibandronic acid Drug Information | CIMS India

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> Indications > Dosage > Administration > Overdosage > Contraindications > Special Precautions > Adverse Drug Reactions > Drug Interactions > Food Interaction > Lab Interference > Pregnancy Category (US FDA) > Mechanism of Action > CIMS Class > ATC Classification

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Indications Dosage

Listed in Dosage. Adult: PO Prevention and treatment of postmenopausal osteoporosis As ibandronic acid: 150 mg once mthly on the same date each mth or 2.5 mg/day. Prevention of skeletal events in breast cancer and bone metastases As ibandronic acid: 50 mg/day. IV Hypercalcaemia of malignancy As ibandronic acid: 2-4 mg as a single dose. Max: 6 mg/dose. Prevention and treatment of postmenopausal osteoporosis As ibandronic acid: 3 mg once 3 mthly. Prevention of skeletal events in breast cancer and bone metastases As ibandronic acid: 6 mg 3-4 wkly. Click to view ibandronic acid Dosage by Indications Should be taken on an empty stomach. (Must be taken at least 1 hr before the 1st food, drink or medication of the day. Take w/ a full glass of only plain water upon arising for the day & remain in sitting/upright position for at least 1 hr. Do not lie down, eat/drink anything except plain water or take other oral medicines for at least 1 hr. Swallow whole, do not chew/crush/suck.) For action to be taken in the event of accidental overdose ... click to view ibandronic acid Severe renal impairment, uncorrected hypocalcaemia, acute upper GI inflammation, inability to stand or sit upright for at least 60 min (oral). History of bone/joint/muscle pain; dysphagia, oesophageal disease, gastritis, duodenitis, ulcers. Risk factors for osteonecrosis of the jaw. Pregnancy and lactation. Fever; influenza-like syndrome; electrolyte disturbances; GI disturbances; musculoskeletal pain; headache; rash, allergic dermatitis; anaemia; decreased alkaline phosphatase; hypercholesterolaemia; UTI; local reactions (parenteral); renal impairment (parenteral). Impaired absorption with aluminium, calcium, iron, magnesium compounds. Increased risk of GI or renal adverse effects with NSAIDs. Additive hypocalcaemic effects with aminoglycosides. For caution against potential drug-food interactions ... click to view ibandronic acid For caution against possible drug interference in lab test results ... click to view ibandronic acid
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Food Interaction Lab Interference Pregnancy Category (US FDA)

Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. Mechanism of Action CIMS Class ATC Classification For details of the mechanism of action, pharmacology and pharmacokinetics and toxicology ... click to view ibandronic acid Agents Affecting Bone Metabolism M05BA06 - ibandronic acid ; Belongs to the class of bisphosphonates. Used in the treatment of bone diseases.

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Search related pubmed documents for ibandronic acid by indication/synonym: Hypercalcaemia of malignancy Postmenopausal osteoporosis Prophylaxis of postmenopausal osteoporosis Prophylaxis of skeletal events in patients with breast cancer and bone metastases

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ibandronic acid Drug Information | CIMS India

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