Drug Study Generic Name: Losartan Brand Name: lifezar Dosage: Adult Initially 50 mg once daily.

Maintenance: 25100 mg once or in 2 divided doses daily. Classification: cardiovascular agent; angiotensin ii receptor antagonist; antihypertensive Indication: Treatment of HTN, alone or in combination w/ other antihypertensives. Administration: oral and may be taken with or without food

Action Angiotensin II receptor (type AT1) antagonist acts as a potent vasoconstrict or and primary vasoactive hormone of the renin angiotensin aldosterone system.

Side effects Heartburn Diarrhea Back pain Leg and/or knee pain Numbness in response to touch Congestion , cough and cold/ flu-like symptoms Fatigue anemia

Adverse reaction Dizziness orthostatic hypotension Impaired renal function rarely, rash angioedema raised alanine aminotransferase hyperkalemia and myalgia facial edema Fever angina pectoris second degree AV block arrhythmias, Diarrhea dry mouth anemia gout muscle cramps arthritis anxiety disorder. Rarely, raised liver enzymes values taste disturbances progressing to complete taste loss Severe migraine

Contraindication Pregnancy (category D) Breastfeedi ng renal artery stenosis hyperkale mia hypersensit ivity anuria patients who are hypersensit ive to other sulfonamid e-derived drugs

Nursing consideration Advise patient to comply with dosage schedule, even if feeling better. Tell patient to avoid sodium substitutes because it may contain potassium which can cause hyperkalemia in patients taking drug. Teach patient to avoid sunlight or wear sunscreen because photosensitivity may occur. Inform patient that drug can cause dizziness, fainting or light-headedness. Instruct patient to report drug induced adverse effects

Generic name: Paracetamol Classification: Analgesic and Antipyretic. Indication: Fever, Relief of mild to moderate pain like headaches, muscular aches and pain, toothache, colds, earache, fever due to tonsillectomy, inoculations, and vaccinations.

Action
Inhibits prostaglandin synthesis pain through acts on in the CNS and blocks the impulse a the center,

Side effects
Side effects are well tolerated Cramping Heartburn abdominal distention can be experienced. On a rarity, hypersensitivity reactions.

Adverse reaction
Early signs of toxicity: Anorexia Nausea Diaphoresis generalized weakness within the first 12-24 hours. Late signs of toxicity: Vomiting right upper quadrant tenderness elevated liver function tests within 48-72 hours after ingestion. Antidote: Acetylcystei ne.

Contraindication
Hypersensitivity Intolerance to tartrazine (yellow dye #5), alcohol, table sugar, saccharin

Nursing consideration
If to be given as analgesia, assess onset, type, location, duration of pain. Can be given without regards to meals. Tablets can be crushed. Assess temperature directly before and 1 hour after giving medication. If respirations are <12/min (<20/min in children), withhold the medication and contact the physician. Evaluate for therapeutic response: relief of pain, stiffness, swelling; increasing in joint mobility; reduced joint tenderness; improve grip strength. Therapeutic blood serum level: 10-30 mcg/mL; toxic serum level: >200 mcg/mL.

peripheral action. It hypothalamic heatregulating producing peripheral vasodilation. results antipyresis effect. It in and

produces analgesic

Generic name: Ferrous fumarate Indication: To prevent and treat iron deficiency anemia Dosage: PO Usual range: Up to 600 mg/day, up to 1.2 g/day if needed. Administration: Should be taken on an empty stomach. (Best taken on an empty stomach. May be taken w/ meals to reduce GI discomfort.)

Action Mineral for antianemia *Vital for hemoglobin regeneration, specifically it enables the RBC development and oxygen transport via hemoglobin *Pregnancy Category: A *Pharmacokinetics: Absorption:5-30%intestines Distribution: PB:UK Metabolism: t.: Uk Excretion: Urine, feces, bile *Pharmacodynamics: PO Onset: 4 days Peak: 7-14 days Duration: 3-4 mos

Side effects Bitter taste Constipation Diarrhea Nausea stomach discomfort throat irritation

Adverse reaction Severe allergic reactions rash hives itching difficulty breathing tightness in the chest swelling of the mouth, face, lips, or tongue black, tarry stools blood or streaks of blood in the stool fever vomiting with continuing sharp stomach pain.

Nursing consideration Contraindicated in clients with hemolytic anemia, Peptic ulcer and Ulcerative colitis Administer vitamins with food to prevent GI upset. Caution on intake of chamomile, feverfew, peppermint and St. Johns wort for it interfere with the absorption of iron and other minerals. Increased effect of iron with Vitamin C; decreased effect of tetracycline, antacids, penicillamine Inform clients of side-effects like nausea and vomiting, diarrhea, constipation, epigastric pain and refer to the attending nurse upon occurrence for management. Monitor for adverse reactions like pallor and drowsiness.