1

Internat|ona| Un|vers|ty Iacu|ty of Med|c|ne

Lndocr|ne and Metabo||sm Course
1est
ALlf Passan khlrelsled 8Sc MSc hu
AsslsLanL rofessor of 8lochemlsLry lnLernaLlonal unlverslLy of Afrlca kharLoum Sudan
aLlfkhlrelsled[yahoocom

Student Name

1 Match the hormones the funct|on
1 lnsulln a sLlmulaLes Lhe Lhyrold gland ( )
2 yLocln b decreases blood calclum levels ( )
3 sLrogen c causes lacLaLlon of Lhe breasLs ( )
4 lucagon d sLlmulaLes Lhe ovarles and Lhe LesLes ( )
S @hyroln e regulaLes Lhe meLabollsm of Lhe body ( )
6 rolacLln f malnLalns Lhe uLerlne llnlng afLer ovulaLlon ( )
7 AldosLerone g lncreases Lhe recovery of salL by Lhe kldneys ( )
8 Adrenalln h lncreaser hearL raLe and blood pressure and sugar levels ( )
9 alclLonln l causes uLerus Lo conLracL for blrLh and breasLs Lo lacLaLe ( )
10@esLosLerone [ sLlmulaLes Lhe adrenal corLe of Lhe adrenal glands ( )
11rogesLerone k speeds up Lhe removal of sugar from Lhe blood sLream ( )
12 rowLh Pormone l causes Lhe lncreased release of glucose lnLo Lhe blood sLream ( )
13uLLlnlzlng Pormone m m sLlmulaLes Lhe folllcle cell Lo release hormones ( )
14olllcleSLlmulaLlng P n sLlmulaLes Lhe growLh of female se organs ( )
1S@hyroldSLlmulaLlng P o sLlmulaLes Lhe growLh of male se organs ( )
16 AdrenocorLlcoLroplc P p sLlmulaLes Lhe kldneys Lo conLrol Lhe amounL of waLer reLalned ( )
17 AnLldlureLlc Pormone q lncrease faLLyacld meLabollsm and amlno aclds upLake by cells ( )


2 Match the g|and to the |ocat|on |n the body
1 lLulLary gland a sllghLly below Lhe laryn ( )
2 Adrenal gland b n Lop of Lhe kldneys ( )
3 @hyrold gland c ln Lhe pelvlc cavlLy ( )
4 ancreas d ouLslde Lhe pelvlc cavlLy ( )
S @esLes e ALLached Lo Lhe base of Lhe braln ( )
6 varles f below Lhe sLomach near Lhe llver ( )


3 March the hormone to the g|and that secretes |t
1 |tu|tary g|and 1 lnsulln ( ) 2 rowLh hormone ( ) 3 Adrenallne ( )
2 Adrena| g|and 4 sLrogen ( ) 3 @hyrolne ( ) 6 yLocln ( )
3 1hyro|d g|and 7 @esLosLerone ( ) 8 alclLonln ( ) 9 orLlsol ( )
4 ancreas 10 MelaLonln ( ) 11 rogesLerone ( ) 12 lucagon ( )
S 1estes
6 Cvar|es




2

4 1rue Ia|se uest|ons
1 @he maln purpose of Lhe endocrlne sysLem ls for Lhe proLecLlon of Lhe body ( )
2 Ponnones are Lhe same as Lhe enzymes LhaL help ln dlgesLlon ( )
3 Pormones are released only lnLo Lhe blood sLream ( )
4 AdrenocorLlcoLroplc hormone ls released by Lhe adrenal gland Lo conLrol Lhe plLulLary ( )
S rogesLerone hormone ls released by Lhe ovarles ( )
6 @he adrenal glands are boLh an endocrlne and eocrlne glands ( )
7 @he plLulLary gland release hormones LhaL conLrol oLher glands and growLh ( )
8 uLehlzlng hormone ls released by ovarles
9 yLocln acLs on boLh Lhe uLerus and Lhe breasL of a female before she ls pregnanL ( )
10@he growLh and developmenL of Lhe genlLals ls a secondary se characLerlsLlc ( )






Se|ect the on|y one best or correct response for each of the fo||ow|ng quest|ons


S Wh|ch of the fo||ow|ng hormones does not d|sso|ve |n the b|ood and thus requ|re carr|er prote|ns?
a AnLldlureLlc hormone
b @hyrolne
c Adrenallne
d rosLaglandln
e lnsulln

6 Wh|ch of the fo||ow|ng |s a funct|on of |nsu||n?
a SLlmulaLes gluconeogenesls
b SLlmulaLes glycogenolysls
c SLlmulaLes hepaLlc llpase
d lncreases blood glucose level
e hosphorylaLlon and use of glucose

7 Wh|ch hormone wou|d be the best |nd|cator of pregnancy?
a sLrogen
b rogesLerone
c luLenlzlng hormone
d olllcle sLlmulaLlng hormone
e Puman chorlonlc gonadoLropln

8 A ch||d presents w|th |egbone deform|ty 8|ood test|ng shows h|gh |eve|s of v|tam|n D |n the b|ood Wh|ch of the
fo||ow|ng |s most ||ke|y?
a @ype l rlckeLs
b @ype ll rlckeLs
c 8enal sLones
d cess 123P2u3
e alclLonln deflclency



3

9 1he fo||ow|ng statement about arathyro|d normone (1n) |s not true
a @P lncreases urlnary cycllc AM ecreLlon
b @P ls secreLed from Lhe paraLhyrold glands as a prepro form
c arboyl fragmenLs of @P are cleared by Lhe kldney
d @he relaLlonshlp beLween eLracellular fluld () calclum and @P secreLlon ls nonllnear
e @he blologlcal acLlvlLy of Lhe @P resldes wlLhln lLs amlnoLermlnal reglon

10now |s rote|n k|nase A (kA) act|vated?
a kA blnds Lo a recepLor Lyroslne klnase and ls phosphorylaLed by Lhe recepLor
b cAM blnds Lo Lhe regulaLory subunlLs and Lhe caLalyLlc subunlLs are released
c proLelnllnked recepLor slgnalllng leads Lo lncreased cyLosollc a2+ levels whlch ln Lurn acLlvaLe kA
d kA blnds Lo lnoslLol phosphollplds on Lhe cyLosollc face of Lhe plasma membrane leadlng Lo acLlvaLlon of lLs
caLalyLlc domaln
e @bound 8as blnds Lo Lhe nLermlnus of kA and causes a conformaLlonal change Lo acLlvaLe kA

11keceptor tyros|ne k|nase prote|ns conta|n a|| of the fo||ow|ng structura| features LkCL1
a a llgase domaln
b a dlmerlzaLlon domaln
c a cyLosollc klnase domaln
d a cyLosollc phosphaLase domaln
e an eLracellular llgand blndlng domaln

12Wh|ch of the fo||ow|ng |s NC1 a common |ntrace||u|ar second messenger?
a a
2+

b 12dlacylglycerol (uA)
c 33cycllc M (cM)
d adenoslne LrlphosphaLe (A@)
e lnoslLol 143LrlsphosphaLe (l
3
)


13A|| of the fo||ow|ng statements about the fo||ow|ng hormones and the|r receptor are true LkCL1
a progesLerone blnds Lo an lnLracellular
b growLh facLors blnd Lo cell surface
c corLlsol blnds Lo a cell surface recepLor
d adrenalln blnds Lo a cell surface recepLor
e esLrogen blnds Lo a member of Lhe sLerold recepLor superfamlly

14Wh|ch one of the fo||ow|ng statements regard|ng parathyro|d hormone (1n) |s not true?
a lL acLs on Lhe guL Lo lncrease calclum absorpLlon
b lL sLlmulaLes renal synLhesls of 123 dlhydroyvlLamln u
c lLs level may be elevaLed ln pseudohypoparaLhyroldlsm
d lL shares blologlcal acLlvlLy wlLh @PrelaLed proLeln (@P8)
e lL promoLes reabsorpLlon of calclum from Lhe glomular fllLraLe

1S1he fo||ow|ng statements concern|ng the pancreas are true nt
1 @he pancreas recelves parL of lLs arLerlal supply from Lhe splenlc arLery
2 @he maln pancreaLlc ducL opens lnLo Lhe Lhlrd parL of Lhe duodenum
3 @he unclnaLe process of Lhe pancreas pro[ecLs from Lhe head of Lhe pancreas
4 @he blle ducL (common blle ducL) lles posLerlor Lo Lhe head of Lhe pancreas
S @he Lransverse mesocolon ls aLLached Lo Lhe anLerlor border of Lhe pancreas

4

161he fo||ow|ng statements concern|ng the |eft suprarena| g|and are |ncorrect n
1 lL eLends behlnd Lhe lnferlor vena cava
2 lL ls separaLed from Lhe lefL kldney by Lhe pararenal faL
3 lLs veln dralns lnLo Lhe lefL renal veln
4 lL ls usually locaLed on Lhe upper pole and laLeral border of Lhe lefL kldney
S e) @he medulla ls lnnervaLed by posLgangllonlc sympaLheLlc nerve flbres

171he fo||ow|ng statements concern|ng the p|tu|tary g|and (hypophys|s cerebr|) are correct n
1 lL ls separaLed from Lhe opLlc chlasma by Lhe dlaphragma sellae
2 @he sphenold slnus ls lnferlor Lo lL
3 lL recelves lLs arLerlal supply from Lhe lnLernal caroLld arLery
4 lL ls suspended from Lhe floor of Lhe Lhlrd venLrlcle by Lhe pars anLerlor
S e) lL ls deeply placed wlLh Lhe sella Lurclca of Lhe skull

18A 40yearo|d truck dr|ver has had d|ff|cu|ty us|ng h|s s|de m|rrors for traff|c beh|nd h|m ne has never had any
ma[or med|ca| prob|ems |n the past ne v|s|ts an optometr|st who determ|nes he has b|tempora| hem|anops|a
but h|s v|s|on |s 20]20 A head C1 scan revea|s s||ght en|argement of the se||a turc|ca Wh|ch of the fo||ow|ng
hormones |s most ||ke|y be|ng secreted |n excess|ve amounts |n th|s man?
a AnLldlureLlc hormone
b rolacLln
c A@P
d rowLh hormone
e uLelnlzlng hormone



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