8one |s composed of ce||s prote|n matr|x and m|nera| depos|ts Lhe cells are of Lhree baslc Lypes O CsLeoblasL O CsLeocyLes O CsLeoclasL luncLlons of 8ones W SupporL W roLecLlon W MovemenL W Mlneral sLorage W 8lood cell formaLlon W ConLrlbuLes Lo body shape and form 8ones are classlfled by Lhelr shape Lwo baslc Lypes of osseous Llssue compacL or dense cancellous or spongy CompacL or dense looks smooLh and homogeneous Cancellous or spongy ls composed of small needle llke or flaL pleces of bone called Lrabeculae and has a good deal of open space Lhe Lrabeculae form a neLwork and Lhe spaces beLween Lhe Lrabeculae are fllled wlLh red or yellow bone marrow |ass|f|cat|on of 8ones Long bones long bones are conslderably longer Lhan Lhey are wlde lL ls consLrucLed prlmarlly of compacL bone buL may conLaln subsLanLlal amounLs of spongy bone ln lLs lnLerlor Are deslgned for welghL bearlng and movemenL 2 ShorL bones Are roughly cube llke 1hey conLaln mosLly spongy bone compacL bone provldes [usL Lhelr Lhln surface layer 1he sesamold bones are a speclal Lype of shorL bone embedded wlLhln a Lendon (ex aLella or knee cap) 3 llaL 8ones Are Lhln flaLLened and unusually a blL curved 1hey have Lwo roughly parallel compacL bone surfaces wlLh a layer of spongy bone beLween Are lmporLanL slLes for hemaLopolesls and frequenLly provlde vlLal organ proLecLlon 4 rregular 8ones all of Lhese bones have compllcaLed shapes and conslsLs malnly of spongy bone enclosed by Lhln layers of compacL bone
erlosLeum O a dense flbrous membrane LhaL covers Lhe bone O lL nourlshes Lhe bone and allows for lLs growLh lL also provldes aLLachmenL of Lendons and llgamenLs O ConLalns nerves blood vessels and lymphaLlcs O Lhe layer closesL Lo Lhe blne conLalns osLeoblasLs w/c are bone formlng cells LndosLeum O s a th|n vascu|ar membrane that covers the marrow cav|ty of |ong bones and cance||ous bone O CsLeoclasLs whlch dlssolve bone Lo malnLaln Lhe marrow cavlLy are locaLed nera Lhe endosLeum ln Powshlp's lacunae 8one Marrow O s a vascular Llssue locaLed ln Lhe medullary (shafL) cavlLy of long bones and ln flaL bones O ed bone marrow ls locaLed malnly ln Lhe sLernum lleum verLebrae and rlbs ln adulLs and ls responslble for produclng red and whlLe blood cells O 8one lormaLlon (osLeogenesls) O CsslflcaLlon ls Lhe process by whlch Lhe bone maLrlx (collagen flbers and ground subsLance) ls formed and hardenlng mlnerals are deposlLed on Lhe collagen flbers O 1he collagen flbers glve Lenslle sLrengLh Lo Lhe bone and Lhe calclum provldes compresslonal sLrengLh 1wo baslc process of osslflcaLlon Lndochondral 2 nLramembranous
8one MalnLenance 1he lmporLanL regulaLlng facLors LhaL deLermlne Lhe balance beLween bone formaLlon and bone resopLlon lnclude Lhe ff Local sLress IlLamln u araLhyrold hormone and CalclLonln 8lood supply 8one Peallng lracLure heallng occurs ln four areas W 8one marrow W 8one corLex W erlosLeum W LxLernal sofL Llssue Slx sLages of fracLure heallng W Accordlng Lo 8uckwaLer (2000) PemaLoma and lnflammaLlon 2 Anglogenesls and carLllage formaLlon 3 CarLllage calclflcaLlon 4 CarLllage removal 3 8one formaLlon 6 emodellng
1he ArLlcular sysLem Lhe [uncLlon of Lwo bones ls called a [olnL (arLlculaLlon) 1here are Lhree baslc klnds of [olnLs W SynarLhrosls W AmphlarLhrosls W ularLhrosls Several Lypes of dlarLhrosls [olnLs W 8allandsockeL [olnLs W Plnge [olnLs W Saddle [olnLs W lvoL [olnLs O Clldlng [olnLs r o|nt capsu|e a Lough flbrous sheaLh LhaL surround Lhe arLlculaLlng bones Lhe synovlum llnes Lhe capsule whlch secreLes Lhe lubrlcaLlng and shockabsorblng synovlal fluld lnLlo Lhe [olnL capsule r LlgamenLs llbrous connecLlve Llssue bands LhaL blnd Lhe arLlculaLlng bones LogeLher r 8ursa s a sac fllled synovlal fluld LhaL cushlons Lhe movemenL of Lendons llgamenLs and bones aL a polnL of frlcLlon
nS1Ck Structure and Iunct|on of the Ske|eta| Musc|e System Muscles of Lhe body are composed of parallel groups of muscle cells(fasclcull) encased of flbrous Llssue called fascla(eplmyslum) 1he more Lhe muscle cells lL conLalns Lhe more Lhe movemenL would be preclse SkeleLal muscles are lnvolved ln body movemenL posLure and heaLproducLlon funcLlons Ske|eta| Musc|e contract|on Lach muscle cell conLalns myoflbrlls whlch conLalns sarcomeres and Lhese sarcomeres conLaln Lhlck myosln and Lhln acLln fllamenLs Sarcomeres are Lhe acLual conLracLlle unlLs of skeleLal muscle cells Muscle cells conLracL ln response Lo elecLrlcal sLlmulaLlon dellvered by an effecLor nerve cell aL Lhe moLor end plaLe 1hese muscle cells Lhen depolarlzes and generaLes an acLlon poLenLlal 1hese Lhen propagaLe along Lhe muscle cell membrane and lead Lo Lhe release of calclum lons LhaL are sLored ln Lhe sarcoplasmlc reLlcula An lncrease ln calclum lons wlll lead Lo lnLeracLlon of Lhe acLln and myosln LhaL wlll lead Lo conLracLlon of muscles Lnergy ls used ln conLracLlon and relaxaLlon 1he source of energy ls Lhe Lhe adenoslne LrlphosphaLe(A1) whlch s generaLed Lhrough cellular oxldaLlve meLabollsm uurlng low levels of acLlvlLy Lhe skeleLal muscles Lhen synLheslzes A1 from Lhe oxldaLlon of glucose Lo waLer and carbon dloxlde uurlng sLrenuous acLlvlLy when oxygen ls noL LoLally avallable glucose ls meLabollzed prlmarlly Lo lacLlc acld SLored muscle glycogen ls used Lo supply glucose durlng perlods of acLlvlLy uurlng muscle conLracLlon noL all of Lhe energy ls consumed ln every acLlvlLy some are used ln heaL form uurlng lsomeLrlc conLracLlon almosL all of Lhe energy ls released ln Lhe form of heaL n Lhls conLracLlon Lhe lengLh of Lhe muscle remalns consLanL buL Lhe force generaLed ls lncreased Whlle durlng lsoLonlc conLracLlon some of Lhe energy ls expended ln mechanlcal work and Lhls conLracLlon ls characLerlzed by shorLenlng of Lhe muscles wlLh no lncrease ln Lhe muscle Lenslon Myoglobulln ls a hemogloblnllke proLeln plgmenL presenL ln sLrlaLed muscle cells LhaL LransporL oxygen Muscles conLalnlng llLLle myoglobulln(whlLe muscles) conLracLs fasLer whlle muscles LhaL conLalns many of Lhese myoglobulln(red muscles) conLracLs slowly buL powerfully Musc|e tone Muscle Lone ls produced by Lhe malnLenance of some of Lhe muscle flbers ln conLracLed sLaLe Muscle Lone ls mlnlmal durlng sleep and lncreased when Lense and anxlous A muscle LhaL ls llmp and wlLhouL Lone ls descrlbed as flaccld Muscles wlLh greaLer Lhan normal Lone ls descrlbed as spasLlc Muscle acLlon 1he prlme mover ls Lhe muscle LhaL causes a parLlcular moLlon 1he muscle LhaL asslsLs Lhe prlme mover are known as synerglsLs 1he muscle causlng movemenL opposlLe Lo LhaL of Lhe prlme mover are called anLagonlsLs Lxerc|se D|suse kepa|r PyperLrophy ls Lhe resulL from an lncrease ln Lhe slze of lndlvldual muscle flbers wlLhouL an lncrease ln Lhelr number PyperLrophy perslsLs only when exerclse ls conLlnued Age and dlsuse cause loss of muscular funcLlon as flbroLlc Llssue replaces Lhe conLracLlle muscle Llssue 1he decrease ln slze of muscle ls called aLrophy When muscles are ln[ured Lhey need resL and lmmoblllzaLlon unLll Llssue repalr occurs 1he healed muscles Lhen needs progresslve exerclse Lo resume lLs preln[ury sLrengLh and funcLlonal ablllLy ASSLSSMLN1 nea|th n|story ommon Symptoms paln Lenderness LlghLness and abnormal sensaLlons a|n When paln ls noL relleved by lmmoblllzaLlon lL would be because of lnfecLlon or severe compllcaLlons 1he nurse should assess for body allgnmenL pressure from LracLlon and Lenslon on skln W 8one paln dull deep ache and borlng W Muscular paln soreness or achlng muscle cramps W lracLure paln sharp and plerclng relleved by lmmoblllzaLlon W Sharp paln due Lo bone lnfecLlon wlLh muscle spasm or pressure on sensory nerve A|tered sensat|on 1he paLlenL may descrlbe paresLheslas whlch are burnlng Llngllng sensaLlons or numbness 1hese may be caused by pressure on nerves or by clrculaLlon lmpalrmenL SofL Llssue swelllng or dlrecL Lrauma Lo Lhese sLrucLures can lmpalr Lhelr funcLlon ast hea|th Soc|a| and Iam||y n|story CccupaLlon( uoes Lhe paLlenL's work requlre physlcal acLlvlLy or heavy llfLlng?) exerclse paLLerns dleLary lnLake(calclum and vlLamln u) and concurrenL healLh condlLlons(uM hearL dlsease CCu lnfecLlon arLhrlLls)
nSAL ASSLSSMLN1 CI 1nL MUSULCSkLLL1AL IUN1CN hys|ca| Assessment O 1he exLenL of assessmenL depends on Lhe paLlenL's physlcal complalnLs healLh hlsLory and physlcal clues LhaL warranL furLher exploraLlon O 1he assessmenL ls focuslng on Lhe paLlenL's ablllLy Lo perform acLlvlLles of dally llvlng O 1echnlques used LhaL are common lnspecLlon and palpaLlon Assess|ng the osture O 1he normal curvaLure of Lhe splne ls convex Lhrough Lhe Lhoraclc porLlon and concave Lhrough Lhe cervlcal and lumbar porLlons O Common ueformlLles kyphosls an lncreased forward curvaLure of Lhe Lhoraclc splne Lordosls or sway back an exaggeraLed curvaLure of Lhe lumbar splne Scollosls a laLeral curvlng devlaLlon of Lhe splne O uurlng lnspecLlon of Lhe splne Lhe enLlre back buLLocks and legs are exposed O 1he examlner lnspecLs Lhe splnal curves and Lrunk symmeLry from posLerlor and laLeral vlews O 1he gluLeal folds are normally symmeLrlcal O Shoulder and hlp symmeLry as well as Lhe llne of Lhe verLebral column are lnspecLed wlLh Lhe paLlenL erecL and wlLh Lhe paLlenL bendlng forward Assess|ng the Ga|t O L ls assessed by havlng Lhe paLlenL walk away from Lhe examlner for a shorL dlsLance O SmooLhness and rhyLhm ls observed O Llmplng moLlon ls noLed lf lL ls caused by a palnful welghL bearlng O LlmlLed [olnL moLlon also affecLs galL Assess|ng the 8one ntegr|ty O 8ones are assessed for deformlLles and allgnmenL O SymmeLry of Lhe body parLs are also assessed O ShorLened exLremlLles bone Lumors ampuLaLlons and fracLures are also noLed O MovemenL of fracLured parL should be mlnlmlzed Lo avold furLher ln[ury Assess|ng the o|nt Iunct|on O 1he arLlcular sysLem ls evaluaLed by noLlng range of moLlon deformlLy sLablllLy and nodular formaLlon O CM ls evaluaLed boLh acLlvely and passlvely O reclse measuremenL of CM ls done by a gon|ometer ( a proLracLor deslgned for evaluaLlng [olnL moLlon) O LlmlLed CM can be caused by SkeleLal deformlLy !olnL paLhology ConLracLure ( shorLenlng of surroundlng [olnL sLrucLures) O f [olnL moLlon ls compromlsed or [olnL ls palnful Lhe [olnL ls examlned for effus|on( excesslve fluld wlLhln Lhe capsule) swelllng and lncreased ln LemperaLure LhaL maL reflecL acLlve lnflammaLlon O L can be assessed by ldenLlfylng for Lhe balloon slgn and for Lhe balloLLemenL of Lhe knee O !olnL deformlLy may also be caused by ConLracLure ulslocaLlon SubluxaLlon (parLlal separaLlon of arLlcular surface) ulsrupLlon of sLrucLures surroundlng Lhe [olnL O alpaLlon of Lhe [olnL whlle lL ls passlvely moved provldes lnformaLlon abouL Lhe lnLegrlLy of Lhe [olnL O normally [olnL moves smooLhly O 1he Llssue surroundlng Lhe [olnL ls examlned for nodule formaLlon O Slze of Lhe [olnL ls ofLen exaggeraLed by aLrophy of Lhe muscles proxlmal and dlsLal Lo LhaL [olnL 1hls ls common ln rheumaLold arLhrlLls of Lhe knees Musc|e Strength and S|ze O Weakness of Lhe group may lndlcaLe varleLy of condlLlons such as W olyneuropaLhy W LlecLrolyLe lmbalance (parLlcularly poLasslum and calclum) W MyasLhenla gravls W ollomyellLls W Muscular dysLrophy O 1he nurse can deLermlne Lhe muscle Lone by palpaLlng Lhe muscle whlle passlvely movlng Lhe relaxed exLremlLy O 1he nurse assesses muscle sLrengLh by havlng Lhe paLlenL perform cerLaln maneuvers wlLh and wlLhouL added reslsLance O 1he nurse may ellclL muscle c|onus (rhyLhmlc conLracLlon of a muscle) O Iasc|cu|at|on (lnvolunLary LwlLchlng of muscle flber groups) may be observed O 1o monlLor lncreased slze due Lo exerclse edema or bleedlng lnLo Lhe muscle Lhe nurse measures Lhe glrLh of an exLremlLy O 1he unaffecLed exLremlLy ls measured and used as Lhe reference sLandard for Lhe affecLed exLremlLy O L ls lmporLanL LhaL Lhe measuremenLs be Laken aL Lhe same locaLlon on Lhe exLremlLy and wlLh Lhe exLremlLy ln Lhe same poslLlon wlLh Lhe muscle aL resL O MeasuremenLs are Laken aL Lhe maxlmum clrcumference of Lhe exLremlLy W lor ease of serlal assessmenL Lhe nurse may lndlcaLe Lhe polnL of measuremenL by marklng Lhe skln W IarlaLlons ln slze greaLer Lhan cm are consldered slgnlflcanL Sk|n O nurse lnspecLs Lhe skln for Ldema 1emperaLure Color O alpaLlon can reveal wheLher any areas are Warmer SuggesLlng lncreased Llssue perfuslon or lnflammaLlon SuggesLlng decreased Llssue perfuslon Ldema presenL O CuLs brulses skln color and lnflammaLlon can lnfluence nurslng managemenL of musculoskeleLal condlLlons
Neurovascu|ar Status O Cne of Lhe compllcaLlons LhaL needs Lo be assessed ls Lhe comparLmenL syndrome (when Lhere ls lncreased Llssue perfuslon wlLhln a llmlLed space LhaL compromlses Lhe clrculaLlon and Lhe funcLlon of Lhe Llssue wlLhln Lhe conflned area Nerve 1est of sensat|on 1est of movement eroneal nerve rlck Lhe skln mldway beLween Lhe greaL and second Loe Ask Lhe paLlenL Lo dorslflex Lhe fooL and exLend Lhe Loes 1lblal nerve rlck Lhe medlal and laLeral surface of Lhe sole Ask Lhe paLlenL Lo planLar flex Loes and fooL adlal nerve rlck Lhe skln mldway beLween Lhe Lhumb and second flnger Ask Lhe paLlenL Lo sLreLch ouL Lhe Lhumb Lhen Lhe wrlsL and Lhen Lhe flngers aL Lhe meLacarpal [olnLs ulnar nerve rlck Lhe dlsLal faL pad of Lhe small flnger Ask Lhe paLlenL Lo abducL all flngers Medlan nerve rlck Lhe Lop or dlsLal surface of Lhe lndex flnger Ask Lhe paLlenL Lo Louch Lhe Lhumb Lo Lhe llLLle flnger Also observe wheLher Lhe paLlenL can flex Lhe wrlsL
nd|cators of er|phera| Neurovascu|ar Dysfunct|on ClrculaLlon Color pale cyanoLlc or moLLled 1emperaLure cool Caplllary reflll more Lhan 3 seconds 2 MoLlon Weakness aralysls 3 SensaLlon aresLhesla unreLenLlng paln aln on passlve sLreLch Absence of feellng
I D|agnost|c Lva|uat|on mag|ng rocedures O Oray stud|es
Orays are a form of lonlzlng radlLlon LhaL can peneLraLe Lhe body Lo form an lmage on fllm O ray sLudles are lmporLanL ln evaluaLlng paLlenLs wlLh musculoskeleLal dlsorders 8one xrays deLermlne bone denslLy LexLure eroslon and changes ln bone relaLlonshlps MulLlple xrays are needed for full assessmenL of Lhe sLrucLure belng examlned Oray sLudy of Lhe corLex of Lhe bone reveals any wldenlng narrowlng or slgns of lrregularlLy !olnL xrays reveal fluld lrregularlLy spur formaLlon narrowlng and changes ln Lhe [olnL sLrucLure AfLer belng poslLloned for Lhe sLudy Lhe paLlenL musL remaln sLlll whlle Lhe xrays are Laken
Spur splked pro[ecLlng body
O omputed tomography
A compuLed Lomography (C1) scan shows ln deLall a speclflc plane of lnvolved bone and can reveal Lumors of Lhe sofL Llssue or ln[urles Lo Lhe llgamenLs or Lendons L ls used Lo ldenLlfy Lhe locaLlon and exLenL of fracLures ln areas LhaL are dlfflculL Lo evaluaLe (eg aceLabulum) C1 sLudles lasL abouL hour 1he paLlenL musL remaln sLlll durlng Lhe procedure
O Magnet|c kesonance mag|ng
MagneLlc resonance lmaglng (M) ls a nonlnvaslve lmaglng Lechnlque LhaL uses magneLlc flelds radlo waves and compuLers Lo demonsLraLe abnormallLles (le Lumors or narrowlng of Llssue paLhways Lhrough bone) of sofL Llssues such as muscle Lendon carLllage nerve and faL 8ecause an elecLromagneL ls used paLlenLs wlLh any meLal lmplanLs cllps or pacemakers are noL candldaLes for M
1o enhance vlsuallzaLlon of anaLomlc sLrucLures conLrasL medla may be ln[ecLed lnLravenously uurlng Lhe procedure Lhe paLlenL needs Lo lle sLlll for Lo 2 hours and wlll hear a rhyLhmlc knocklng sound aLlenLs who experlence clausLrophobla may be unable Lo LoleraLe Lhe conflnemenL of closed M equlpmenL wlLhouL sedaLlon Cpen M sysLems are avallable buL Lhey use lowerlnLenslLy magneLlc flelds whlch reduces Lhe quallLy of Lhe lmaglng repeaLed lmaglng may be requlred AdvanLages of open M lnclude lncreased paLlenL comforL reduced problems wlLh clausLrophoblc paLlenLs and reduced nolse
O Arthrography
ArLhrography ls a Lype of xray examlnaLlon LhaL uses a conLrasL agenL Lo lmage an anaLomlcal [olnL such as Lhe knee shoulder elbow or wrlsL An arLhrogram demonsLraLes Lhe sLrucLures of Lhe [olnL lncludlng carLllage llgamenLs and bursa (Lhe fluldfllled [olnL capsule)
ArLhrography ls useful ln ldenLlfylng acuLe or chronlc Lears of Lhe [olnL capsule or supporLlng llgamenLs of Lhe knee shoulder ankle hlp or wrlsL A radlopaque subsLance or alr ls ln[ecLed lnLo Lhe [olnL cavlLy Lo ouLllne sofL Llssue sLrucLures and Lhe conLour of Lhe [olnL 1he [olnL ls puL Lhrough lLs range of moLlon Lo dlsLrlbuLe Lhe conLrasL agenL whlle a serles of xrays ls obLalned f a Lear ls presenL Lhe conLrasL agenL leaks ouL of Lhe [olnL and ls evldenL on Lhe xray lmage
AfLer an arLhrogram Lhe [olnL ls usually resLed for 2 hours and a compresslon elasLlc bandage ls applled as prescrlbed n addlLlon Lhe nurse provldes comforL measures (mlld analgesla lce) as approprlaLe 1he nurse should explaln Lo Lhe paLlenL LhaL lL ls normal Lo experlence cllcklng or crackllng ln Lhe [olnL for a day or Lwo afLer Lhe procedure unLll Lhe conLrasL agenL or alr ls absorbed
Nurs|ng ntervent|ons for mag|ng rocedures
8efore Lhe paLlenL undergoes an lmaglng sLudy Lhe nurse should assess for condlLlons LhaL may requlre speclal conslderaLlon durlng Lhe sLudy or LhaL may be conLralndlcaLlons Lo Lhe sLudy (eg pregnancy clausLrophobla lnablllLy Lo LoleraLe requlred poslLlonlng due Lo age deblllLy or dlsablllLy meLal lmplanLs) L ls essenLlal LhaL Lhe paLlenL remove all [ewelry halr cllps hearlng alds and oLher meLal before havlng an M f conLrasL agenLs wlll be used for C1 scan M or arLhrography Lhe nurse should carefully assess Lhe paLlenL for posslble allergy
8CNL DLNS1CML1k
8one denslLomeLry ls used Lo esLlmaLe bone mlneral denslLy (8Mu) 1hls can be done Lhrough Lhe use of xrays or ulLrasound uualenergy xray absorpLlomeLry (uLOA) deLermlnes bone mlneral denslLy aL Lhe wrlsL hlp or splne Lo esLlmaLe Lhe exLenL of osLeoporosls and Lo monlLor a paLlenL's response Lo LreaLmenL for osLeoporosls 8one sonomeLry (ulLrasound) measures heel bone quanLlLy and quallLy and ls used Lo esLlmaLe 8Mu and Lhe rlsk of fracLure for people wlLh osLeoporosls 8one denslLy sonography ls a cosL effecLlve readlly avallable screenlng Lool for dlagnoslng osLeoporosls and predlcLlng a person's rlsk for fracLure
8one denslLomeLry checks an area of Lhe body such as Lhe hlp hand or fooL for slgns of mlneral loss and bone Lhlnnlng
n Lhe pasL osLeoporosls could only be deLecLed afLer you broke a bone 8y LhaL Llme however your bones could be qulLe weak A bone denslLy LesL makes lL posslble Lo know your rlsk of breaklng bones before Lhe facL A bone denslLy LesL uses Orays Lo measure how many grams of calclum and oLher bone mlnerals are packed lnLo a segmenL of bone A bone denslLy LesL ls a falrly accuraLe predlcLor of your rlsk of fracLure 8CNL SAN A bone scan ls a nuclear scannlng LesL LhaL ldenLlfles new areas of bone growLh or breakdown L can be done Lo evaluaLe damage Lo Lhe bones flnd cancer LhaL has spread (meLasLaslzed) Lo Lhe bones and monlLor condlLlons LhaL can affecL Lhe bones (lncludlng lnfecLlon and Lrauma) A bone scan can ofLen flnd a problem days Lo monLhs earller Lhan a regular Oray LesL lor a bone scan a radloacLlve Lracer subsLance ls ln[ecLed lnLo a veln ln Lhe arm 1he Lracer Lhen Lravels Lhrough Lhe bloodsLream and lnLo Lhe bones 1hls process may Lake several hours A speclal camera (gamma) Lakes plcLures of Lhe Lracer ln Lhe bones 1hls helps show cell acLlvlLy and funcLlon ln Lhe bones Areas LhaL absorb llLLle or no amounL of Lracer appear as dark or cold spoLs whlch may lndlcaLe a lack of blood supply Lo Lhe bone (bone lnfarcLlon) or Lhe presence of cerLaln Lypes of cancer Areas of rapld bone growLh or repalr absorb lncreased amounLs of Lhe Lracer and show up as brlghL or hoL spoLs ln Lhe plcLures PoL spoLs may lndlcaLe problems such as arLhrlLls Lhe presence of a Lumor a fracLure or an lnfecLlon A bone scan may be done on Lhe enLlre body or [usL a parL of lL A bone scan ls done Lo O llnd bone cancer or deLermlne wheLher a cancer from anoLher area such as Lhe breasL lung kldney Lhyrold gland or prosLaLe gland has spread (meLasLaslzed) Lo Lhe bone See a plcLure of a bone scan showlng Lhe spread of cancer O Pelp dlagnose Lhe cause or locaLlon of unexplalned bone paln such as ongolng low back paln A bone scan may be done flrsL Lo help deLermlne Lhe locaLlon of an abnormal bone ln complex bone sLrucLures such as Lhe fooL or splne lollowup evaluaLlon Lhen may be done wlLh a compuLed Lomography (C1) scan ormagneLlc resonance lmaglng (M) O Pelp dlagnose broken bones such as a hlp fracLure or a sLress fracLure noL clearly seen on O ray O llnd damage Lo Lhe bones caused by lnfecLlon or oLher condlLlons such asageLs dlsease Ak1nkCSC ArLhroscopy (also called arLhroscoplc surgery) ls a mlnlmally lnvaslve surglcal procedure ln whlch an examlnaLlon and someLlmes LreaLmenL of damage of Lhe lnLerlor of a [olnL ls performed uslng an arLhroscope a Lype of endoscope LhaL ls lnserLed lnLo Lhe [olnL Lhrough a small lnclslon ArLhroscoplc procedures can be performed elLher Lo evaluaLe or Lo LreaL many orLhopedlc condlLlons lncludlng Lorn floaLlng carLllage Lorn surface carLllage ACL reconsLrucLlon and Lrlmmlng damaged carLllage 1he advanLage of arLhroscopy over LradlLlonal open surgery ls LhaL Lhe [olnL does noL have Lo be opened up fully nsLead for knee arLhroscopy for example only Lwo small lnclslons are made one for Lhe arLhroscope and one for Lhe surglcal lnsLrumenLs Lo be used ln Lhe knee cavlLy Lo fully remove Lhe knee cap 1hls reducesrecovery Llme and may lncrease Lhe raLe of surglcal success due Lo less Lrauma Lo Lhe connecLlve Llssue L ls especlally useful for professlonal aLhleLes who frequenLly ln[ure knee [olnLs and requlre fasL heallng Llme 1here ls also less scarrlng because of Lhe smaller lnclslons rrlgaLlon fluld ls used Lo dlsLend Lhe [olnL and make a surglcal space SomeLlmes Lhls fluld leaks lnLo Lhe surroundlng sofL Llssue causlng exLravasaLlon and edema 1he surglcal lnsLrumenLs used are smaller Lhan LradlLlonal lnsLrumenLs Surgeons vlew Lhe [olnL area on a vldeo monlLor and can dlagnose and repalr Lorn [olnL Llssue such as llgamenLs and menlscl or carLllage L ls Lechnlcally posslble Lo do an arLhroscoplc examlnaLlon of almosL every [olnL ln Lhe human body 1he [olnLs LhaL are mosL commonly examlned and LreaLed by arLhroscopy are Lhe knee shoulder elbow wrlsL ankle fooL and hlp I CS1LCCkCSS
What |s Csteoporos|s?
A condlLlon characLerlzed by a decrease ln Lhe denslLy of bone decreaslng lLs sLrengLh and resulLlng ln fraglle bones CsLeoporosls llLerally leads Lo abnormally porous bone LhaL ls compresslble llke a sponge 1hls dlsorder of Lhe skeleLon weakens Lhe bone and resulLs ln frequenL fracLures ln Lhe bones CsLeoporosls can be presenL wlLhouL any sympLoms for decades because osLeoporosls doesnL cause sympLoms unLll bone fracLures
k|sk Iactors
Iema|e gender Caucaslan or Aslan race 1hln and small body frame lamlly hlsLory of osLeoporosls (for example havlng a moLher wlLh an osLeoporoLlc hlp fracLure doubles your rlsk of hlp fracLure) ersonal hlsLory of fracLure Lack of exerclse uleL low ln calclum oor nuLrlLlon and poor general healLh Low esLrogen levels ln women (such as occur ln menopause or wlLh early surglcal removal of boLh ovarles) Low LesLosLerone levels ln men (hypogonadlsm) mmoblllLy such as afLer a sLroke or from any condlLlon LhaL lnLerferes wlLh walklng When vlLamln u ls lacklng Lhe body cannoL absorb adequaLe amounLs of calclum from Lhe dleL Lo prevenL osLeoporosls IlLamln u deflclency can resulL from lack of lnLesLlnal absorpLlon of Lhe vlLamln such as occurs ln cellac sprue and prlmary blllary clrrhosls
What factors determ|ne bone strength? 8one mass (bone denslLy) ls deLermlned by Lhe amounL of bone presenL ln Lhe skeleLal sLrucLure Cenerally Lhe hlgher Lhe bone denslLy Lhe sLronger Lhe bones 8one denslLy ls greaLly lnfluenced by geneLlc facLors whlch ln Lurn are someLlmes modlfled by envlronmenLal facLors and medlcaLlons lor example men have a hlgher bone denslLy Lhan women and Afrlcan Amerlcans have a hlgher bone denslLy Lhan Caucaslan or Aslan Amerlcans normally bone denslLy accumulaLes durlng chlldhood and reaches a peak by around age 23 8one denslLy Lhen ls malnLalned for abouL 0 years AfLer age 33 boLh men and women wlll normally lose 0303 of Lhelr bone denslLy per year as parL of Lhe aglng process LsLrogen ls lmporLanL ln malnLalnlng bone denslLy ln women When esLrogen levels drop afLer menopause loss of bone denslLy acceleraLes uurlng Lhe flrsL flve Lo 0 years afLer menopause women can suffer up Lo 24 loss of bone denslLy per year! 1hls can resulL ln Lhe loss of up Lo 2330 of Lhelr bone denslLy durlng LhaL Llme perlod 1he acceleraLed bone loss afLer menopause ls a ma[or cause of osLeoporosls ln women referred Lo as posLmenopausal osLeoporosls
I lAC1uL CompleLe lracLure enLlre clrcumference of Lhe bone ls lmpalred ncompleLe lracLure lnvolves a break Lhrough only parL of Lhe crosssecLlon of Lhe bone CommlnuLed lracLure bone has spllnLered lnLo several fragmenLs Closed lracLure does noL cause a break ln Lhe skln Cpen lracLure Lhe skln or mucous membrane wound exLends Lo Lhe fracLured bone ulsplaced lracLure bone pleces are ouL of normal allgnmenL Cne or boLh pleces may be ouL of allgnmenL mpacLed lracLure a bone fragmenL ls drlven lnLo anoLher bone fragmenL aLhologlc lracLure caused by bone's belng weakened elLher by pressure from a Lumor or an acLual Lumor wlLhln Lhe bone CreensLlck lracLure one slde of a bone ls broken and Lhe oLher slde ls benL Llnear lracLure a fracLure LhaL exLends parallel Lo Lhe long axls of a bone buL does noL dlsplace Lhe bone Llssue Cbllque lracLure Lhe llne of break goes dlagonal along Lhe bone LonglLudlnal lracLure occurs along Lhe lengLh of Lhe bone 1ransverse lracLure bone fracLured horlzonLally Splral lracLure a fracLure LhaL LwlsLs around Lhe shafL of Lhe bone SLellaLe a fracLure ln whlch Lhere are numerous flssures radlaLlng from Lhe cenLral polnL of lmpacL or ln[ury LhroughouL surroundlng bone Llssue Colles'lracLure dlsLal fracLure of Lhe radlus ln Lhe forearm wlLh dorsal (posLerlor) dlsplacemenL of Lhe wrlsL oLL's lracLure fracLure of Lhe lower parL of Lhe flbula wlLh serlous ln[ury of Lhe lower Llblal arLlculaLlon usually a chlpplng off of a porLlon of Lhe medlal malleolus or rupLure of Lhe medlal llgamenL ArLlcular lracLure fracLure lnvolvlng Lhe [olnL surface of a bone LxLracapsular lracLure any fracLure LhaL occurs near a [olnL buL does noL dlrecLly lnvolve Lhe [olnL capsule nLracapsular lracLure a fracLure wlLhln Lhe capsule of a [olnL Lplphyseal lracLure a fracLure lnvolvlng Lhe eplphyseal plaLe of a long bone whlch causes separaLlon or fragmenLaLlon of Lhe plaLe AngulaLlon lracLure a fracLure ln whlch Lhe fragmenLs of bone are aL angles Lo one anoLher Avulslon lracLure a fracLure ln whlch a fragmenL of bone has been pulled away by a Lendon and lLs aLLachmenL 8lowouL lracLure fracLure of Lhe orblLal floor caused by a sudden lncrease of lnLraorblLal pressure due Lo LraumaLlc force Compresslon lracLure bone has been compressed laLlgue or March lracLure resulLs from excesslve physlcal acLlvlLy and noL from any speclflc ln[ury
aLhophyslology
redlsposlng lacLors MoLor Iehlcle AccldenLs and lalls reclplLaLlng lacLors CsLeoporosls or meLasLaLlc bone cancer lracLure occurs ulrecL lorce ndlrecL lorce 1he perlosLeum and blood vessel ln Lhe corLex Marrow surroundlng sofL Llssues are dlsrupLed 8leedlng occurs PemaLoma lorms Cllnlcal ManlfesLaLlon ueformlLy Swelllng 8rulslng Muscle Spasm 1enderness aln mpalred SensaLlon (numbness) Loss of normal funcLlon Abnormal moblllLy CreplLus Pypovolemlc Shock
8one Llssue lmmedlaLely ad[acenL Lo fracLure dles necroLlc Llssue sLlmulaLes an lnLense lnflammaLory response
IasodllaLlon LxudaLlon of plasma and leukocyLes nfllLraLlon of oLher W8C
8one Peallng Larly CompllcaLlons LongLerm CompllcaLlons 8CnL PLALnC SLage onePemaLoma lormaLlon WlLhln 24 hours Lhe blood cloL beglns Lo organlze As Lhe blood ln Lhe hemaLoma cloLs (coagulaLes) a loose dellcaLe mesh of flbrln forms around Lhe fracLure slLe 1he flbrln mesh proLecLlvely encloses Lhe damaged bone and acLs as a scaffold for Lhe lngrowLh of caplllary buds and flbroblasLs new caplllarles sLarL Lo grow lnLo Lhe cloLLed hemaLoma AfLer 24 hours Lhe maln blood supply lncreases Lo Lhe fracLured bone ends L undergoes changes and develops lnLo granulaLlon Llssue SLage LwoCellular rollferaLlon 1hls sLage Lakes place aL Lhe fracLured slLe where Lorn ends of perlosLeum endosLeum and bone marrow supply Lhe cells LhaL prollferaLe and dlfferenLlaLe lnLo flbrocarLllage hyallne carLllage and flbrous connecLlve Llssues AfLer several days Lhe comblnaLlon of perlosLeal elevaLlon and Lhe granulaLlon Llssue forms a collar around Lhe end of each fragmenL 1he collars evenLually advance unlLe and form a brldge across Lhe fracLure slLe SLage Lhreerocallus lormaLlon Slx Lo Len days afLer ln[ury Lhe granulaLlon Llssue changes and a provlslonal callus forms newly formed carLllage and bone maLrlx (derlved ln parL from Lhe undamaged perlosLeum and endosLeum of ad[acenL bone marglns) dlsperse Lhrough Lhe sofL Llssue callus n uncompllcaLed fracLure Lhe provlslonal callus usually reaches lLs maxlmal slze abouL 4 Lo 2 days afLer Lhe ln[ury 1hls mass ls subsequenLly remodeled SLage fourCsslflcaLlon A permanenL callus of Lrue rlgld bone evenLually forms by Lhe deposlLlon of calclum salLs whlch knlLs Lhe fracLured bone ends LogeLher CsslflcaLlon flrsL forms an exLernal callus (beLween Lhe perlosLeum and corLex) nexL an lnLernal callus (medullary plug) and flnally an lnLermedlaLe callus (beLween Lhe corLlcal fragmenLs) SLage llveConsodllaLlon and emodellng 8one remode||ng Lhe flnal phase of bone heallng goes on for several monLhs n remodellng bone conLlnues Lo form and becomes compacL reLurnlng Lo lLs orlglnal shape n addlLlon blood clrculaLlon ln Lhe area lmproves Cnce adequaLe bone heallng has occurred welghLbearlng (such as sLandlng or walklng) encourages bone remodellng nCnSuCCAL MAnACLMLn1 CLCSLu LuuC1Cn L ls Lhe mosL common nonsurglcal meLhod for managlng a slmple fracLure Whlle applylng a manual pull or LracLlon on Lhe bone Lhe healLh care provlder manlpulaLes Lhe ends so LhaL Lhey reallgn 8AnuACLS Anu SLn1S lor cerLaln areas of Lhe body such as scapula and clavlcle an elasLlc bandage or commerclal moblllze may be used Lo lmmoblllze Lhe bone durlng heallng 8ecause upper exLremlLy welghL spllnLs may be sufflclenL Lo keep bone fragmenLs ln place 1hermoplasL a durable flexlble maLerlal for spllnLlng allows cusLom flLLlng Lo Lhe cllenL's parL CAS1S lor more complex fracLures or fracLures of Lhe lower exLremlLy Lhe physlclan or orLhopedlc Lechnlclan applles casL Lo hold bone fragmenLs ln place afLer reducLlon s a rlgld devlce LhaL lmmoblllzes Lhe affecLed body parL whlle allowlng oLher body parLs Lo move May be applled for correcLlon of deformlLles (such as clubfooL) or for prevenLlon of deformlLles (such as Lhose seen ln some cllenLs wlLh rheumaLold arLhrlLls) 1?LS Cl CAS1S 1?L and CPAAC1LS1CS Cl CAS1 uSL uL LO1LM1? CAS1S ShorLarm CasL
Longarm CasL
Panglngarm casL
1humb splca Shoulder Splca
SLable fracLures of Lhe wrlsL (meLacarpals carpals or dlsLal radlus) unsLable fracLures of Lhe wrlsL dlsLal humerus radlus or ulna lracLures of Lhe humerus LhaL cannoL be allgned by LAC (llghL LracLlon ls posslble whlle Lhe cllenL ls ln bed or by an aLLached sLrap LhaL exLends around Lhe neck) lracLures of Lhe Lhumb unsLable fracLures of Lhe shoulder glrdle or humerus dlslocaLlons of Lhe shoulder LCWL LO1LM1? CAS1S ShorLleg casL Longleg casL
lracLures of Lhe ankle meLaLarsals or fooL unsLable fracLures of Lhe Llbla flbula or ankle Walklng casL Leg Cyllnder Longleg Cyllnder Same as for SLC or LLC SLable fracLures of Lhe Llbla flbula or knee SLable fracLures of Lhe dlsLal femur proxlmal Llbla or knee CAS1 8ACLS aLellar welghLbearlng casL LxLernal polycenLrlc knee hlnge casL
MldshafL or dlsLal shafL fracLures of Lhe femur Same as for Lhe paLellar welghLbearlng casL 8Cu? CAS1S Plp splca lsser's casL Palo casL
ulslocaLlon of Lhe hlp pelvlc or hlp ln[urles Scollosls Lhoraclc splnal fracLures lracLures of Lhe cervlcal splne
CAS1 S?nuCML Also called superlor mesenLerlc arLery syndrome" an uncommon buL serlous compllcaLlon ls mosL ofLen seen ln orLhopedlc cllenLs who have been placed ln a hlp splca or body casL arLlal or compleLe upper lnLesLlnal obsLrucLlon resulLs classlc sympLoms abdomlnal dlsLenLlon eplgasLrlc paln nausea and vomlLlng arLlal obsLrucLlon occurs lnlLlally from compresslon of Lhe Lhlrd porLlon of duodenum beLween Lhe superlor mesenLerlc arLery and Lhe aorLa CAS1 CAL WlLh a plasLer casL lL ls parLlcularly lmporLanL Lo warn Lhe cllenL abouL Lhe heaL LhaL wlll be felL lmmedlaLely afLer Lhe weL casL ls applled When a cllenL wlLh a weL plasLer casL ls moved and Lurned Lhe casL ls handled wlLh Lhe palms of Lhe hands Lo prevenL lndenLaLlons and resulLanL areas of pressure on Lhe skln lor prevenLlng conLamlnaLlon by urlne or feces Lhe perlneal area of a dry long leg or body casL ls encased ln a plasLlc proLecLlve coverlng Check Lo ensure LhaL Lhe casL ls noL Loo LlghL and frequenLly monlLor Lhe cllenL's neurovascular sLaLus usually every hour for Lhe flrsL 24 hours afLer appllcaLlon mmedlaLely reporL Lo Lhe healLh care provlder any sudden lncreases ln Lhe amounL of dralnage or change ln Lhe lnLegrlLy of Lhe casL CAS1 CCMLCA1CnS nfecLlon mosL ofLen resulLs from Lhe breakdown of skln under Lhe casL (pressure necrosls) f Lhe pressure of Lhe necrosls occurs cllenL Lyplcally complalns of a very palnful hoL spoL" under Lhe casL and Lhe casL may feel warmer ln Lhe affecLed area ClrculaLlon lmpalrmenL and perlpheral nerve damage can resulL from consLrlcLlon of Lhe casL 8ecause of prolonged lmmoblllzaLlon a [olnL may become conLracLed usually ln flxed sLaLe of flexlon or a degeneraLlve arLhrlLls may develop from lack of welghL bearlng whlch ls necessary for carLllage vlablllLy 1AC1Cn s Lhe appllcaLlon of a pulllng force Lo a parL of Lhe body Lo provlde reducLlon allgnmenL and resL Can also decrease muscle spasm (Lhus rellevlng paln) and prevenL or correcL deformlLy and Llssue damage Mechanlcal 1racLlon can elLher be ConLlnuousas ln fracLure LreaLmenL nLermlLLenLfor rellef of muscle spasm ln oLher Lypes of musculoskeleLal/neurologlc Lrauma such as cervlcal nerve rooL compresslon ClasslflcaLlon of 1racLlon unnlng 1racLlonLhe pulllng force ls one dlrecLlon and cllenL's body acLs as counLerLracLlon 8alanced Suspenslonprovldes Lhe counLerLracLlon so LhaL pulllng force of Lhe LracLlon ls noL alLered when Lhe bed or cllenL ls moved 1?LS Cl 1AC1Cn 1ypes and characLerlsLlcs of 1racLlon use upper LxLremlLy 1racLlon Sldearm skln or skeleLal LracLlon
Cverhead or 9090 LracLlon
lasLer 1racLlon
lracLures of Lhe humerus wlLh or wlLhouL lnvolvemenL of Lhe shoulder and clavlcle Same as above (depends on physlclan's preference) lracLures of Lhe wrlsL LCWL LO1LM1? 1AC1Cn 8uck's exLenslon LracLlon
lracLures of Lhe hlp or femur preoperaLlvely revenLlon of hlp flexlon conLracLures Plp dlslocaLlon ussell's 1racLlon 8alanced skln or skeleLal LracLlon lracLures of Lhe hlp or end of Lhe femur lracLures of Lhe femur or pelvls (aceLabulum) SnAL CCLuMn Anu LLIC 1AC1Cn Cervlcal halLer Cervlcal skeleLal
elvlc 8elL
elvlc sllng
Cervlcal muscle spasms sLraln/spraln or arLhrlLls Cervlcal fracLures of Lhe splne Muscle spasms aln sLraln spraln or muscles spasms ln Lhe lower back elvlc fracLures oLher pelvlc ln[urles
SuCCAL MAnACLMLn1 LCLA1IL CAL lor sLablllzlng Lhe fracLure Lhe cllenL may be placed ln LracLlon before surgery 1hls procedure ls Lyplcal for managlng fracLured hlp when 8uck's LracLlon may be used preoperaLlvely CLA1IL CCLuuLS Cpen reducLlon wlLh lnLernal flxaLlon (Cl) ls a common meLhod ln reduclng and lmmoblllzlng a fracLure When Lhls meLhod ls noL feaslble exLernal flxaLlon wlLh closed reducLlon ls used Cl 8ecause Lhls permlLs early moblllzaLlon lL ls ofLen Lhe preferred surglcal meLhod for an older adulL who ls suscepLlble Lo Lhe compllcaLlon of moblllLy CLn LuuC1Cn Allows Lhe surgeon dlrecL vlsuallzaLlon of Lhe fracLure slLe n1LnAL lOA1Cn uses meLal plns screws rods or prosLheses Lo lmmoblllze Lhe fracLure durlng heallng 1he surgeon makes an lnclslon Lo galn access Lo Lhe broken bone and lmplanLs one or more devlces LO1LnAL lOA1Cn AfLer Lhe fracLure reducLlon Lhe physlclan makes small percuLaneous lnclslons so LhaL plns may be lmplanLed lnLo Lhe bone All plns are selfdrllllng LO1LnAL lOA1Cn AuIAn1ACLS Anu uSAuIAn1ACLS AuIAn1ACLS 1here ls mlnlmal blood loss ln comparlson wlLh lnLernal flxaLlon 1he devlce allows early ambulaLlon and exerclse of Lhe affecLed body parL whlle rellevlng paln 1he devlce malnLalns allgnmenL ln closed fracLures LhaL wlll noL malnLaln poslLlon ln a casL and sLablllzes commlnuLed fracLures LhaL requlre bone grafLlng n open fracLures ln whlch skln and Llssue Lrauma accompanles Lhe fracLure Lhe devlce permlLs easy access Lo Lhe wound and promoLes heallng uSAuIAn1ACL n1AC1 nlLC1Cncan lead Lo osLeomyellLls whlch ls dlfflculL Lo LreaL CCuLA LO1LnAL lOA1Cn s someLlmes used Lo LreaL new fracLures (closed commlnuLed and open fracLures wlLh bone loss) as well as malunlon or nonunlon of fracLures L may also be used Lo LreaL congenlLal bone deformlLles especlally ln chlldren A clrcular exLernal flxaLlon devlce sLlmulaLes bone growLh CS1CLA1IL CAL rocedures for nonunlon LLLC1CAL 8CnL S1MuLA1Cn s based on research showlng LhaL bone has lnherenL elecLrlcal properLles LhaL are used ln heallng 1he exacL mechanlsm of acLlon ls unknown 8CnL CAl1nC May also replaced dlseased bone or lncrease bone Llssue for [olnL replacemenL 8CnL 8AnknC f quallfled cllenLs undergolng LoLal hlp replacemenL may donaLe Lhelr femoral heads Lo Lhe bank for laLer use as bone grafLs for oLher cllenLs LCW n1LnS1? uLSLu uL1ASCunu (Lxogen Lherapy) used for slowheallng fracLures or for new fracLures as an alLernaLlve Lo surgery ulLrasound LreaLmenL ylelded excellenL resulLs uuC 1PLA? CenLral and muscle relaxanLs such as carlsoprodol (Soma) cyclobenzaprlne (llexerll) meLhocarbamol (obaxln) may be prescrlbed for rellef of paln assoclaLed wlLh muscle spasm n open fracLure Lhe LhreaL of LeLanus can be reduced wlLh LeLanus and dlphLherla Loxold or LeLanus lmmunoglobulln for Lhe paLlenL who has noL been lmmunlzed 8one peneLraLlng anLlbloLlcs such as cephalosporln (eg cefazolln (kefzol Ancef)) are used prophylacLlcally
LlLLnCLS O 8lack ! M and Pawks ! P (2009) MeJlcol sotqlcol ootsloq cllolcol moooqemeot fot posltlve ootcomes 8 Lh ed SL Louls Mlssourl Saunders Llselver O gnaLavlclus u u and Workman M L (2006) MeJlcol sotqlcol ootsloq ctltlcol tblokloq fot collobototlve cote 3 Lh ed uSA Llselver Saunders O McCance k L and PueLher S L (2006) 9otbopbysloloqy 1be bloloqlc bosls fot Jlseose lo oJolt ooJ cbllJteo 3 Lh ed uSA Llselver Saunders O Monahan l u eL al (2007) 9blpps meJlcol sotqlcol ootsloq neoltb ooJ llloess petspectlves 8 Lh ed SL Louls Mlssuorl Mosby Llselver O SmelLzer S and 8are 8 (2008) toooet ooJ 5oJJottbs textbook of meJlcol sotqlcol ootsloq Lh ed uSA LlpplncoLL Wllllams and Wllklns
1esL quesLlons 1o a paLlenL wlLh aLelecLasls perfuslon exceeds venLllaLlon Lherefore _________ exlsLs a uead Space b ShunLs c SllenL unlL d Cardlogenlc shock 2 Whlch of Lhe common phenomena LhaL may alLer bronchlal dlameLer whlch affecLs alrway reslsLance Lo a paLlenL wlLh Lumor and mucus ln Lhe lungs a CbsLrucLlon of Lhe alrway b ConLracLlon of Lhe bronchlal smooLh muscle c 1hlckenlng of bronchlal mucosa d Loss of lung elasLlclLy 3 1he normal amounL of pleural fluld ln Lhe pleural space a 23 Lo 30 ml b 3 Lo 23 ml c 0 Lo 20 ml d 3 Lo 3 ml 4 1he followlng are Lhe slgns and sympLoms of pulmonary Luberculosls LOCL1 a rrlLablllLy b nlghL SweaLs c PemopLysls d laLlgablllLy 3 L ls a LesL used Lo deLermlne wheLher a person has been lnfecLed wlLh 18 baclllus 1hls ls also sLandardlzed lnLracuLaneous ln[ecLlon procedure and should be performed only by Lhose Lralned ln lLs admlnlsLraLlon and readlng a ManLoux MeLhod b u LesL c All of Lhe above d none of Lhe above