About Stemcord

ABOUT STEMCORD: Inception: 6 March 2002 Number of employees: 19 (including three of the founding directors) Number of samples stored
at StemCord: More than 11,000
Singapores Most Experienced Cord Blood Bank First autologous, private cord blood bank in Singapore Licensed by Singapores Ministry of Health (MOH) Largest private cord blood bank in Singapore, having collected, processed and stored over 10,000 cord blood samples Wide network of representative offices in Brunei, Indonesia, The Philippines and Vietnam With the fiscal viability to sustain long-term cord blood banking activities Highest Standards of Quality Control Audited by MOH Uses stringent criteria set by the American Association of Blood Banks (AABB) in the collection, processing and storage of cord blood samples Acquiring accreditation with the Foundation of Accredited Cellular Therapy (FACT) that has a strong focus in stem cell banking Owns two dedicated laboratories and storage facilities Backed By Trusted Medical Expertise Founded and managed by distinguished practising medical oncologists, haematologists and physicians with vast contributions in bone marrow and peripheral stem cell transplantation programmes in Singapore StemCords laboratory has processed, stored and successfully used the stem cells from the blood or bone marrow of patients with various cancers, in conventional stem cell transplants
Copyright@2007 StemCord Pte Ltd. All rights reserved. Company Registration Number: 200006824C Office: Gleneagles Medical Centre, 6 Napier Road #02-13, Singapore 258499. Tel: (65) 6471 2002 Fax: (65) 6471 5255 Laboratories: The Rutherford, 89A Science Park Drive 1, #04-28, Singapore 118261. Tel: (65) 6777 5443 Fax: (65) 6774 4556 The Gemini, 41 Science Park Road #01-21, Singapore 117610 Website: www.stemcord.com
Stemcord Agreement_.indd 1
Stemcord Agreement CL907-66 / 4150
9/17/07 4:07:25 PM
Some Interesting Technical Details: Safe and Secure Storage Methods Only cord blood bank in Singapore that stores cord blood in multiple cryo units, giving the flexibility to use only what is needed Splits the storage of units at its two separately located laboratories as an added precaution
StemCord is the only cord blood bank in Singapore that stores cord blood in multiple cryo units for multiple usages
Advantages of Storing Cord Blood in Multiple Units Maximises the potential for multiple treatments Enables the storage of optimal concentration of cells per unit. No possibilities of cross-contamination as units are hermetically sealed. Each unit is specifically designed for long-term cryogenic storage at low temperature. Furthermore, with promising developments using stem cells in Regenerative Therapy, having stem cells in multiple storage units will provide the capacity for multiple treatments if needed.
9/17/07 4:07:27 PM
The StemCord Advantage: Storage in Multiple Units

Multiple Units Allows for the release of part of the sample to be thawed, expanded, and used in treatment, while the remaining samples are left in storage for future use Optimal concentration of stem cells per unit Multiple usage especially with the onset of cell-expansion technology Some diseases, such as heart disease, stroke and spinal cord injury, require only one cryo unit of cord blood for therapeutic use Gives the option of splitting the storage into two separate locations Single Unit One-time use because once thawed, cord blood cannot be re-frozen No possibility of additional usage as the cell expansion bag is connected to the main bag and the whole unit has to be thawed together Cracks in bags have been documented and are detected only when the bags are thawed. If all stem cells are stored in 1 unit that has a crack, then there is no reserve for used in the future.
9/17/07 4:07:29 PM
Stem Cells and Their Clinical Applications

What are stem cells?
Stem cells are the body's very early unspecialised master cells. They have two distinct characteristics: Can self-renew through cell division for the duration of our life Have the remarkable potential to develop into other types of cells and tissue, such as red or white blood cells, platelets, nerve cells, brain cells or even the cells of the heart. They serve as a repair system for the body, continuously replenishing other cells.
Source: http://www.cordbloodusa.org/articles-a5-Cord_Blood_Stem_Cell.htm
What are cord blood stem cells?

Cord blood stem cells are a perfect match for the baby and carry a significant probability of match in other family members. Studies consistently demonstrate that umbilical cord blood is an effective alternative source of haematopoietic stem cells (HSC) for adult transplantation with at least comparable results to other HSC sources for adult patients.
Source: C. Brunstein, P. Szabolcs: Moving Umbilical Cord Blood Transplantation to Adult Patients, International Society of Cellular Therapy Conference Plenary Session 7: Cord Blood, Berlin, May 4-7, 2006.
9/17/07 4:07:30 PM
Diseases Treatable With Stem Cells

Acute Leukemias Acute Biphenotypic Leukemia Acute Lymphocytic Leukemia (ALL) Acute Myelogenous Leukemia (AML) Acute Undifferentiated Leukemia Chronic Leukemias Chronic Lymphocytic Leukemia (CLL) Chronic Myelogenous Leukemia (CML) Juvenile Chronic Myelogenous Leukemia (JCML) Juvenile Myelomonocytic Leukemia (JMML) Myelodysplastic Syndromes Amyloidosis Chronic Myelomonocytic Leukemia (CMML) Refractory Anemia (RA) Refractory Anemia with Excess Blasts (RAEB) Refractory Anemia with Excess Blasts in Transformation (RAEB-T) Refractory Anemia with Ringed Sideroblasts (RARS) Stem Cell Disorders Aplastic Anemia (Severe) Congenital Cytopenia Dyskeratosis Congenita Fanconi Anemia Paroxysmal Nocturnal Hemoglobinuria (PNH) Myeloproliferative Disorders Acute Myelofibrosis Agnogenic Myeloid Metaplasia (Myelofibrosis) Essential Thrombocythemia Polycythemia Vera Lymphoproliferative Disorders Hodgkin's Disease Non-Hodgkin's Lymphoma Prolymphocytic Leukemia Phagocyte Disorders Chediak-Higashi Syndrome Chronic Granulomatous Disease Neutrophil Actin Deficiency Reticular Dysgenesis Liposomal Storage Diseases Adrenoleukodystrophy Gaucher's Disease Hunter's Syndrome (MPS-II) Hurler's Syndrome (MPS-IH) Krabbe Disease Maroteaux-Lamy Syndrome (MPS-VI) Metachromatic Leukodystrophy Morquio Syndrome (MPS-IV) Mucolipidosis II (I-cell Disease) Mucopolysaccharidoses (MPS) Niemann-Pick Disease Sanfilippo Syndrome (MPS-III) Scheie Syndrome (MPS-IS) Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII) Wolman Disease Histiocytic Disorders Familial Erythrophagocytic Lymphohistiocytosis Hemophagocytosis Histiocytosis-X Langerhans' Cell Histiocytosis Inherited Erythrocyte Abnormalities Beta Thalassemia Major Blackfan-Diamond Anemia Pure Red Cell Aplasia Sickle Cell Disease Congenital (Inherited) Immune System Disorders Absence of T & B Cells SCID Absence of T Cells, Normal B Cell SCID Ataxia-Telangiectasia Bare Lymphocyte Syndrome Common Variable Immunodeficiency DiGeorge Syndrome Kostmann Syndrome Leukocyte Adhesion Deficiency Omenn's Syndrome Severe Combined Immunodeficiency (SCID) SCID with Adenosine Deaminase Deficiency Wiskott-Aldrich Syndrome X-Linked Lymphoproliferative Disorder Other Inherited Disorders Cartilage-Hair Hypoplasia Ceroid Lipofuscinosis Congenital Erythropoietic Porphyria Glanzmann Thrombasthenia Lesch-Nyhan Syndrome Osteopetrosis Tay Sachs Disease Inherited Platelet Abnormalities Amegakaryocytosis / Congenital Thrombocytopenia Plasma Cell Disorders Multiple Myeloma Plasma Cell Leukemia Waldenstrom's Macroglobulinemia Other Malignancies Brain Tumors Breast Cancer Ewing Sarcoma Neuroblastoma Ovarian Cancer Renal Cell Carcinoma Small-Cell Lung Cancer Testicular Cancer Autoimmune Diseases Evan Syndrome Multiple Sclerosis (Experimental) Rheumatoid Arthritis (Experimental) Systemic Lupus Erythematosus (Experimental)
9/17/07 4:07:32 PM
Potential Treatable Diseases With Stem Cells In The Future

Alzheimer's Disease Diabetes Heart Disease Liver Disease Muscular Dystrophy Parkinson's Disease Spinal Cord Injury Stroke
Source: Chen, Jieli, et al., Experimental Neurology 171, 109-115 (2001); Trends in Cardiovascular Medicine, Nov. 11, 2001 (8:303-307). "Stem Cells Could Remove Need for Liver Transplants," Chicago Tribune, July 25, 2000; "Implanted InsulinProducing Cells Reverse Disease in Mice," Chicago Tribune, March 6, 2000; "Japanese Study Hints of Home-Grown Heart Bypasses," Reuters, November 7, 1999; Ackerman, T., "Baylor Scientist Creates Blood Cells from Muscle Cells in Mice," Houston Chronicle, October 11, 1999; "Researchers Find New Use for Stem Cells," Biotechnology News, Vol. 19, No. 24, October 7, 1999; "Bone Marrow Stem Cells Turn Into Brain Cells in Study," Bloomberg News, September 13, 1999.
Who is suitable for cord blood banking?

Storing cord blood is suitable for every mother unless your obstetrician has cautioned you of a difficult or complicated pregnancy. It is also particularly useful and advisable for: Families with a history of blood disorder or other genetic diseases and cancers Small and single child families Pregnant mothers above 35 years old Sub-fertile couples Couples of different races The first born child.
What are the reasons for storing cord blood?

More and more families have chosen to collect, process and store their babys cord blood as it: Provides a safe, painless and non-controversial means of acquiring stem cells Has the potential to treat a range of diseases including a wide range of diseases including both common and cancers / blood disorders, such as the sickle cell anemia, thalassemia and leukemia Is generally preferred in stem cell transplantation because of a lower complication rate compared to bone marrow transplantation Can be readily made available should the need arise (if stored in a private cord blood bank), thus eliminating the time needed to search for a matching donors stem cells and allowing treatment to begin promptly Guarantees a 100% perfect match for the baby Can potentially increase the odds of having a match for their siblings and parents Is recognised as one of the most promising medical treatments for the future.
9/17/07 4:07:34 PM
StemCord Offices
Laboratories: 89A Science Park Drive 1, The Rutherford #04-28, Singapore 118261 Tel: +65 6777 5443 Fax: +65 6774 4556 Marketing office: Gleneagles Medical Centre, 6 Napier Road, #02-13, Singapore 258499 Tel: +65 6471 2002 Fax: +65 6471 5255 Overseas offices: StemCord Indonesia Tamara Center, suite 608, Jl. Jend. Sudirman kav 24, Jakarta 12920, Indonesia tel 62-21 5206555/ 6556 fax 62-21 52006551 Email: info@stemcord.com StemCord Phillipines, Inc 1407 Quezon Avenue, Quezon City 1104, The Philippines Trunk Lines : +632 373 3311 to 18 Direct Line: +632 373 7359 Mobile No: +63918 918 0329 Fax No: +632 373 3293 Email: stemcordphils@bayandsl.com
9/17/07 4:07:37 PM
How Do Clients Get Started

1. Call 6471 2002 to register or visit www.stemcord.com for more information. Our Client Relations Executive will meet up with you to provide you with more details 2. Register with StemCord (preferably before 28th week of pregnancy) by: Signing the full set of agreements Completing a Medical Health History form Making payment (by cheque, credit card of cash)
You will receive a Cord Blood Collection Kit containing: you o A purpose-designed cord blood collection bag, enclosed in an individual sterile package and a needle and syringe for the doctor to choose the method he is most comfortable with o The correct amount and type of anticoagulant for cord blood preservation o An information sheet for the doctor to fill up
3. Inform your doctor that you have signed up with StemCord 4. On the day of delivery: Bring along the Cord Blood Collection Kit to the hospital Inform the doctor/nurses to collect cord blood, upon the birth of your baby Call our 24-hour hotline 6471 2002 upon the arrival of your baby
9/17/07 4:07:40 PM

About Stemcord

Încărcat de

Informații document

Descriere originală:

Drepturi de autor

Formate disponibile

Partajați acest document

Partajați sau inserați document

Opțiuni de partajare

Vi se pare util acest document?

Este necorespunzător acest conținut?

Drepturi de autor:

Formate disponibile

About Stemcord

Încărcat de

Drepturi de autor:

Formate disponibile

ABOUT STEMCORD: Inception: 6 March 2002 Number of employees: 19 (including three of the founding directors) Number of samples stored

at StemCord: More than 11,000

Stemcord Agreement CL907-66 / 4150

Stemcord Agreement CL907-66 / 4150

The StemCord Advantage: Storage in Multiple Units

Stemcord Agreement CL907-66 / 4150

Stem Cells and Their Clinical Applications

What are cord blood stem cells?

Stemcord Agreement CL907-66 / 4150

Diseases Treatable With Stem Cells

Stemcord Agreement CL907-66 / 4150

Potential Treatable Diseases With Stem Cells In The Future

Who is suitable for cord blood banking?

What are the reasons for storing cord blood?

Stemcord Agreement CL907-66 / 4150

Stemcord Agreement CL907-66 / 4150

How Do Clients Get Started

Stemcord Agreement CL907-66 / 4150

S-ar putea să vă placă și