ZHANYONG SHU 949-502-1195 18 Bahia, Irvine, CA 92614 KEY WORDS

zs12d11c2@westpost.net

Research specialist, Protein Chemistry, Proteomics, Biophysics, Biochemistry; Sr. Research Scientist, Drug Discovery, Drug Development, Nanotechnology. PROFILE Protein Chemistry & Proteomics Protein expression & Purification; Antibody, scFv & Fab production; Mass Spectro scopy & Proteomics. Biophysical Analysis Hands-on experiences in EM, AFM, NMR, CD, DLS, HPLC & Protein Crystallization. Surface Plasmon Resonance Protein/small molecules interaction; Protein/protein interaction; High throughpu t screening. Conjugation chemistry Tumor specific drug delivery; Protein and nucleic acid labeling; Enzymology. PROFESSIONAL EXPERIENCE Abraxis/California Nanosystem Institute in UCLA a" Los Angeles, CA 2008-Pre sent Sr. Scientist a Proficiently supervised scientists in Protein Science group a Drug discovery through nanotechnology a Production & characterization of Vault particles as drug carrier a Production and characterization of Virus-Like Particles (VLP) for vaccine dev elopment a Producing proteins, antibodies and conjugation products for preclinical test a Surface plasma resonance analysis for antigen/antibody, protein/small molecul e compound interaction. University of California Irvine a" Irvine, CA 2003-2008 Research Specialist Department of Biological Chemistry; Department of Developmental & Cell Biology a Protein Chemistry in cancer research a Biophysics, Biochemistry & Enzymology a Mass spectroscopy & Proteomics a Electron microscopy; Atomic force microscopy; protein crystallization University of Texas HSC at San Antonio, TX 1999-2003 Postgraduate Researcher Department of Biochemistry; Department of Biomedicine a Protein Chemistry a Solution dynamics of protein through NMR a Surface plasma resonance; Fluorescence Pennsylvania State University, State College, PA 1998-1999

Postgraduate Researcher Department of Chemistry a RNA folding, protein folding and biophysics a In vitro transcription; RNA mapping; UV, Circular Dichroism EDUCATION Ph.D., Biochemistry, National Laboratory of Biomacromolecules, Chinese Academy o f Sciences. PUBLICATIONS J Biological Chemistry, (2009) 284(31):20812-21. PLoS ONE, (2008) e3763. Journal of Molecular Biology, (2006) 355, 47-62 Biochemistry, (2004) 43(16), 4781-4790. Biochemistry, (2003) 42, 10126-10139. Nature, Structural Biology, (2002) 9(3), 203-208. Acta Biophysica Sinica, (2000) 16(3), 453-458. Biochemistry, (1999) 38, 15369-15379. Journal of Crystal Growth, (1998) 192(1-2), 282-289. Progress in Natural Science, (1997) 7(2), 244-246. Progress in Biochemistry and Biophysics, (1997) 24(5), 396-401. PATENTS 1. Patent Number: CN98203277.3 (CN2353430). An apparatus for crystal growth of biomacromolecules by monitoring and adjusting the water evaporation automatical ly. Patent Inventors: Zhanyong Shu, Ruchang Bi, Ming Li, Xinmin Wang and Yaopin g Wang. http://www.patent-cn.com/B01D/CN2353430.shtml 2. Patent Number: CN98201674.3 (CN2319406). Crystallization Apparatus for Micro gravity study in Space. Patent Inventors: Shimi Fu, Ruchang Bi, Xinmin Wang, Pei dong Jiang, Zhanyong Shu, Huaixing Cang, Huizhen Qiu, Jianqi Hu, yaoping Wang. http://www.patent-cn.com/C07K/CN2319406.shtml