67%(3)67% au considerat acest document util (3 voturi)
9K vizualizări2 pagini
A drug card containing a synopsis of information about this drug regarding dose, mechanism of action, cautions/contraindications. This is the format required for the nursing program I am in.
A drug card containing a synopsis of information about this drug regarding dose, mechanism of action, cautions/contraindications. This is the format required for the nursing program I am in.
Drepturi de autor:
Attribution Non-Commercial (BY-NC)
Formate disponibile
Descărcați ca DOCX, PDF, TXT sau citiți online pe Scribd
A drug card containing a synopsis of information about this drug regarding dose, mechanism of action, cautions/contraindications. This is the format required for the nursing program I am in.
Drepturi de autor:
Attribution Non-Commercial (BY-NC)
Formate disponibile
Descărcați ca DOCX, PDF, TXT sau citiți online pe Scribd
Generic Name Trade Name Classification Dose Route Time/frequency
Piperacillin/tazobactam Zosyn Anti-infectives 2.25gm IVPB Q 6 hrs Peak Onset Duration Normal dosage range End of infusion rapid 4-6 hrs 3.375-4.5 g q 6 hr Rate: Administer over at least 30 min Why is your patient getting this medication For IV meds, compatibility with IV drips and/or solutions Skin and skin structure infections Reconstitute with 5 ml of 0.9% NaCl, sterile or bacteriostatic water for injection, or D5W. Do not use LR--incompatible. Shake well until dissolved. Dilute further in at least 50 ml of diluent. Discard any unused solution after 24 hr at room temperature or 48 hr if refrigerated. Mechanism of action and indications Nursing Implications (what to focus on) (Why med ordered) Contraindications/warnings/interactions Piperacillin: Binds to bacterial cell wall membrane, causing Hypersensitivity to penicillins, betalactams, cephalosporins, or cell death. Spectrum is extended compared with other tazobactam(cross-sensitivity may occur). Renal impairment (dosage penicillins. reduction or increased interval recommended if CCr <40 ml/min). Tazobactam: Inhibits beta-lactamase, an enzyme that can Common side effects destroy penicillins. SEIZURES (HIGHER DOSES), PSEUDOMEMBRANOUS COLITIS, rashes, hypokalemia, phlebitis at IV site, HYPERSENSITIVITY REACTIONS, INCLUDING ANAPHYLAXIS AND SERUM SICKNESS Interactions with other patient drugs, OTC or herbal Lab value alterations caused by medicine medicines (ask patient specifically) Evaluate renal and hepatic function, CBC, serum potassium, and None for this patient bleeding times prior to and routinely during therapy, May cause positive direct Coombs' test result, May cause ↑ BUN, creatinine, AST, ALT, serum bilirubin, alkaline phosphatase, and LDH, May cause leukopenia and neutropenia, especially with prolonged therapy or hepatic impairment, May cause prolonged prothrombin and partial thromboplastin time, Piperacillin may cause ↑ serum sodium and ↓ serum potassium concentrations, Piperacillin/tazobactam may also cause ↓ hemoglobin and hematocrit and thrombocytopenia, eosinophilia, leukopenia, and neutropenia. It also may cause proteinuria; hematuria; pyuria; hyperglycemia; ↓ total protein or albumin; and abnormalities in sodium, potassium, and calcium levels Be sure to teach the patient the following about this medication Advise patient to report signs of superinfection(black furry overgrowth on tongue, vaginal itching or discharge, loose or foul-smelling stools) and allergy. Caution patient to notify health care professional if fever and diarrhea occur, especially if stool contains blood, pus, or mucus. Advise patient not to treat diarrhea without consulting health care professional. May occur up to several weeks after discontinuation of medication. Nursing Process- Assessment Assessment Evaluation (Pre-administration assessment) Why would you hold or not give this med? Check after giving Assess patient for infection (vital signs; Observe patient for signs and symptoms of Resolution of the signs and appearance of wound, sputum, urine, and stool; anaphylaxis (rash, pruritus, laryngeal edema, symptoms of infection. Length of WBC) at beginning of and during therapy, Obtain wheezing). Discontinue the drug and notify time for complete resolution a history before initiating therapy to determine the physician or other health care professional depends on the organism and site previous use of and reactions to penicillins or immediately if these occur. Keep epinephrine, of infection. cephalosporins. Persons with a negative history of an antihistamine, and resuscitation equipment penicillin sensitivity may still have an allergic close by in the event of an anaphylactic response, Obtain specimens for culture and reaction. sensitivity prior to initiating therapy. First dose may be given before receiving results.