Lab 4: Cardiovascular System Meghan Hughes 3343-8468 2057

The purpose of this lab is to show how the baroreceptor reflex helps BP stabilize after a change in physiological situations. When BP decreases, the baroreceptor reflex signals the body to increase HR and TPR to cause an increase in BP so the body can overcome the decrease in BP. It was also to measure subjects HR and BP in response to the static and dynamic exercises. In this lab we demonstrate how the baroreceptor reflex works at rest, immediately after standing, one minute after standing; it was also demonstrated during dynamic exercises and static exercises. For the dynamic exercises we used two subjects, a male and a female, and incrementally measured their BP and HR. This data is collected while they perform two different workloads on the cycle ergometer. The static exercises were similar in that we used two different subjects, a male and a female, and measure their HR and BP incrementally while they performed wall-sits. Female Calculations: Female Amanda SBP DBP HR Weight(kg): Est. VO2 mL/min 58 Est. Q L/min SV mL/beat MAP mmHg TPR mmHg/L/min

mmHg mmHg beat/min

est

R 1 60 120

63

2ml*(1207560 80mm 1 MET* 60)*63]/1000= mL/min/63 120mmHg Hg/75.6 3.5mL/kg/min*58kg=203 7.56 beats/min= +(2*60mmHg) L/min= 1.05 mL/min L/min 120 /3= 80 mmHg mmHg/L/min mL/beat

Male From powerpoint Baroreceptor Reflex Example Data

Position

BP (mmHg)

HR (beats/min) 60

Supine

120/80

80 Standing Immediately 110/75

64 Standing 1 min post 124/80

Weight Male -(kg): Est. SBP DBP HR VO2 mmHg mmHg beat/min mL/min L/min mmHg mL/beat mLO2/100mL Supine Immediately 110 Standing 1 min Post 124 80 64 175 5.6 75 80 175 5.6 86.6 94.6 70 87.5 2.23 2.23 120 80 60 175 4.8 93.3 80 . 3.65 Est. Q MAP SV a-vO2 diff 50

Static Exercise

Subject 1:ANTHONY BW:68kg Heart Rate Blood Pressure

Subject 2:AMANDA BW:58 kg Heart Rate Blood Pressure

Rest

64

100/60

63

120/6

45 Knee bend (1.25 MET) Minute 1

66

120/70

85

125/65

45 Knee bend (1.25 MET) Minute 3 90 Knee bend (1.75 MET) Minute 1 90 Knee bend (1.75 MET) Minute 1

84

150/100

114

120/60

84

140/80

90

130/70

170

145/85

126

140/80

Dynamic Exercise

Subject 1: Brttany BW: 75 kg Heart Rate Blood Pressure

Subject 2:Aaron BW:72.7 kg Heart Rate Blood Pressure

Rest Work Rate 1 Minute 3 Work Rate 1 Minute 6 Work Rate 2 Minute 3 Work Rate 2 Minute 6

60 72

115/70 170/73

57 75

110/75 130/80

101

130/75

108

132/85

115

139/75

126

140/90

127

149/80

132

180/100

Female: Amanda Static Exercise (Wall Sit) S BP m mHg Rest 120 BP m D HR Est. VO2

Weight(kg):58

Est. Q

SV

MAP

TPR

mHg beat/min mL/min 60 60 80 63 114 126 203 253.75 355.25 Weight Female Brittany (kg):

L/min 7.56 13.68 15.12

mL/beat mmHg mmHg/L/min 120 120 120 80 80 100 1.05 .58 .66

1.25 MET 120 1.75 MET 140

75

Dynamic Exercise (Cycle) S BP BP m m L/min 5.4 11.11 mL/beat mmHg mmHg/L/min 90 110 85 93.3 1.57 .83 D HR Est. VO2 Est. Q SV MAP TPR

mHg mHg beat/min mL/min Rest 115 70 75 8 Work Rate 149 80 127 459.3 60 101 262.5 328

Work Rate 130

17.5

138

103

.59

Male:Anthony Static Exercise (Wall Sit) S BP BP m m D HR Est. VO2

Weight(kg):68

Est. Q

SV

MAP

TPR

mHg mHg beat/min mL/min Rest 100 60 100 85 64 84 120 238 297.5 416.5 Weight Male Aaron Dynamic Exercise (Cycle) S BP BP m m D HR Est. VO2 (kg):

L/min 5.1 8.4 8.2

mL/beat mmHg mmHg/L/min 80 100 68 73.3 116.6 105 1.43 1.38 1.28

1.25 MET 150 1.75 MET 145

72.7

Est. Q

SV

MAP

TPR

mHg mHg beat/min mL/min Rest Work Rate 1 Work Rate 2 180 100 132 110 1 85 1 132 445.3 75 8 108 318 57 254.45

L/min 4.0

mL/beat mmHg mmHg/L/min 70 86.7 2.16

10.2

94

100.6

.99

21.2

160

126.7

.60

Discussion: (a)Q:referring to the baroreceptor reflex, what did you expect to happen to BP after standing rapidly from a supine position, what happened to BP after 1 min of standing? A: I expected that BP would rapidly drop because gravity pulls blood quickly toward the feet which results in decreased venous return to the heart. In consequence to the baroreceptor reflex, BP and HR returned to normal after 1 min. (b)Q:what did you expect to see in SV after standing rapidly from a spine position and after 1 min of standing? A:I would expect that SV would drop because HR shoots up after immediately which is inversely proportional to SV and necessary for the baroreceptor reflex. After the body rests for one min after immediately standing, the BP and HR returns to almost normal (c)Q:What is the a-v O2difference?What affect does heavy exercise elicit on the a-v O2 difference and why does this occur? A: difference between venous blood and arterial blood which shows how much oxygen was consumed. The a-v o2 difference would decrease because the body is using much more oxygen during exercise(Thomas). (d) Type HR Systolic Diastolic TPR Venous return Static up up up up same up up Down up down up same up SV CO

Dynamic up

(e) Q:which type of exercise should not be prescribed to a person with congestive heart failure? A: dynamic exercise should not be prescribed to a person with CHF because it involves and increase in CO which would put a strain on their already failing heart.

Works Cited Thomas, Duke, Carlos Gaos, and T.J. Reeves. "American Physiological SocietyJournal of Applied Physiology." Resting Arteriovenous Oxygen Difference and Exercise Cardiac Output. American Physiological Society. Web. 04 Apr. 2012. <http://jap.physiology.org/content/17/6/922.abstract>.