CLS 325 - 435 Final Exam Objectives

Specific Examination Objectives
Average Question Topic ABO AIHA Antibody ID Compatibility Components Donor Testing Donors Genetics HDN Immunology Other Blood Groups Reagents Rh System Transfusion Reactions
Exam ID CLS 325 Final
Total 15 6 4 3 13 2 1 2 12 7 11 8 8 8
Total Questions 100
Difficulty 1.93 1.33 2.00 2.67 1.77 1.50 2.00 2.00 2.25 1.71 1.91 1.88 2.13 1.50
Average Difficulty 1.89
On this examination, the student will be expected to:

1. [Level 2/Final/ABO/4] Differentiate between secretor and nonsecretor status 2.
[Level 2/Final/Other Blood Groups/9]
Describe the relationship between Lewis genes and secretor status 3. [Level 2/Final/ABO/10] Discuss the Bombay phenotype with regard to serologic reactions
[Level 1/Final/ABO/12]
4.
Identify naturally occurring antibodies produced by each ABO Blood Group

5. [Level 1/Final/ABO/13] List alternative blood types that can be given to an individual when an exact match is unavailable
[Level 2/Final/Immunology/14]
6.
Explain how immunodeficiencies can affect blood bank testing

7. [Level 2/Final/ABO/15] Explain Landsteiner's rule
8.
Describe the reciprocal relationship between ABO antigens and antibodies for O, A, B, and AB blood types
9. [Level 2/Final/ABO/33] Describe discrepancies caused by extra reactions in serum (reverse) testing
10.
Interpret routine ABO typing results
Page 1 of 6
See last page for explanation of question levels.
11. [Level 1/Final/AIHA/35] List the most commonly occurring autoimmune hemolytic anemias
[Level 1/Final/AIHA/36]
12.
List causative agents for Cold Agglutinin Disease (CAD)

13. [Level 2/Final/AIHA/37] Discuss initial therapy options for WAIHA
[Level 1/Final/AIHA/40]
14.
List drugs associated with drug-induced IHA that cause membrane modification
15. [Level 1/Final/AIHA/42] List drugs that are associated with drug-independent types of hemolytic anemias
16.
Differentiate between antigens enhanced and destroyed by proteolytic enzymes

17.
Describe the Lewis Blood Group System 18. [Level 3/Final/Other Blood Groups/109] Characterize the U antigen 19.
Describe Donath-Landsteiner antibodies 20. [Level 2/Final/Other Blood Groups/116] Describe autoanti-I antibodies and its disease association 21.
[Level 3/Final/Compatibility/133]
Determine causes of incompatible crossmatch when given test results 22. [Level 3/Final/Compatibility/135] Determine causes of incompatible crossmatch when given test results 23.
[Level 2/Final/Genetics/159]
Explain codominant expression 24. [Level 2/Final/HDN/166] Describe the most serious clinical findings of hemolytic disease of the newborn 25.
[Level 2/Final/HDN/169]
Indicate the appropriate blood product for exchange transfusion 26. [Level 2/Final/HDN/171] Explain ABO-HDN 27.
Calculate the number of vials of RhIg to give a mother 28. [Level 2/Final/Immunology/176] Discuss the role of complement 29.
Differentiate between IgG and IgM antibodies 30. [Level 2/Final/Reagents/180] Discuss the role of LISS
Page 2 of 6
31. [Level 1/Final/Immunology/181] Define zeta potential

32.
Define antigen
33. [Level 2/Final/Transfusion Reactions/195] Describe the causes of febrile nonhemolytic transfusion reactions
[Level 2/Final/Transfusion Reactions/202]
34.
Describe the mechanisms of transfusion hemosiderosis

35. [Level 1/Final/Components/205] List the therapeutic benefits of red blood cells
36.
Discuss the composition and dosage of Rh immune globulin

37.
Discuss the timing of Rh immune globulin 38. [Level 1/Final/HDN/213] Define Hemolytic Disease of the Newborn 39.
Identify antibodies associated with delayed transfusion reactions 40. [Level 2/Final/Other Blood Groups/254] Discuss characteristics of the Duffy Blood Group and its relationship to disease 41.
Differentiate between glycophorin A and glycophorin B 42. [Level 1/Final/Other Blood Groups/259] Be able to list all clinically significant antibodies 43.
Explain the McLeod phenotype and its association with disease 44. [Level 2/Final/Donors/286] Describe donor criteria that indicate a temporary deferral 45.
[Level 2/Final/Donor Testing/295]
Explain the testing procedures for HIV 46. [Level 1/Final/Donor Testing/296] List all required serological tests for blood donors 47.
[Level 1/Final/Components/303]
State the expiration limits for platelets and platelet components 48. [Level 1/Final/Components/305] State the storage temperature and expiration limits for frozen red blood cells 49.
[Level 2/Final/Reagents/333]
Differentiate between polyspecific and monospecific AHG 50. [Level 1/Final/ABO/356] List the immunodominant sugars for A, B, O and H alleles
Page 3 of 6
51. [Level 2/Final/Compatibility/390] Discuss the impact of hemolyzed samples in compatibility testing
52.
Describe the Kleihauer-Betke procedure and how to interpret results

53. [Level 3/Final/HDN/400] Be able to choose who is at risk for ABO HDN if given mother and baby blood types
54.
Determine the type of HDN when presented with a clinical situation

55. [Level 1/Final/Transfusion Reactions/402] Define immune hemolytic anemia
[Level 2/Final/Antibody ID/469]
56.
Discuss how to remove cold reacting antibodies from serum

57.
Describe the different gradings associated with the interpretation of agglutination reactions 58. [Level 1/Final/Reagents/477] State the concentration of red blood cell based reagents 59.
Discuss chemicals that can be used to dissociate IgG without harming the red blood cell 60. [Level 2/Final/Other Blood Groups/492] Differentiate between antigens enhanced and destroyed by proteolytic enzymes 61.
[Level 2/Final/Rh System/503]
Predict the Rh genotypes (Wiener notation) of offspring if given parental genotypes 62. [Level 2/Final/Rh System/507] Be able to convert Wiener notation to Fisher-Race notation 63.
Interpret Fisher-Race genotypes and indicate whether the D antigen is present 64. [Level 2/Final/Rh System/516] Differentiate between D-Deletion and Rh null phenotypes 65.
Be able to convert Wiener notation to Fisher-Race notation 66. [Level 2/Final/Rh System/523] Differentiate between each type of weak D expression 67.
Explain why blood products are irradiated 68. [Level 2/Final/Components/537] Describe the used for fresh frozen plasma and its components 69.
List the most common transfusion related diseases 70. [Level 1/Final/Components/539] List the therapeutic benefits of red blood cells including it's effect on the hematocrit
Page 4 of 6
71. [Level 2/Final/Transfusion Reactions/549] Describe the symptoms of circulatory overload

72.
Differentiate between antigens enhanced and destroyed by proteolytic enzymes

73. [Level 2/Final/Genetics/695] Differentiate between heterozygosity and homozygosity as it relates to genes
74.
Explain the purpose of washing cells prior to IAT testing

75. [Level 2/Final/Reagents/697] Discuss the importance of LISS in antibody detection
76.
Correlate each lectin with its corresponding antigen specificity

77.
Choose the appropriate Wiener genotype that would react with given antisera 78. [Level 2/Final/Components/701] Describe the minimum requirements of one unit of platelets 79.
Be able to list the low incidence antigens 80. [Level 2/Final/Antibody ID/703] Differentiate between antigens enhanced and destroyed by proteolytic enzymes 81.
Determine the ABO discrepancy when given ABO typing results 82. [Level 2/Final/Reagents/705] Explain the purpose of adding IgG sensitized red cells after IAT testing 83.
Choose compatible units for a patient receiving plasma 84. [Level 1/Final/Transfusion Reactions/707] Identify antibodies associated with acute transfusion reactions 85.
Differentiate between universal donor and universal recipient 86. [Level 1/Final/Components/709] Identify appropriate uses of cryoprecipitate 87.
Compare and contrast ABO-HDN and Rh-HDN 88. [Level 3/Final/HDN/711] Calculate the total volume of a fetomaternal hemorrhage (FMH) based on KB results 89.
Describe the Fisher-Race and Wiener theories of inheritance 90. [Level 2/Final/Components/713] Explain how to properly prepare platelet concentrate
Page 5 of 6
91. [Level 2/Final/Transfusion Reactions/714] Explain the purpose of irradiating red blood cells and its components
92.
Discuss characteristics of the Bombay phenotype

93. [Level 2/Final/Reagents/716] Describe the components of IgG sensitized red blood cells
94.
Describe the biochemical changes that occur in stored blood

95. [Level 3/Final/Components/718] Choose compatible units for a patient when given ABO/Rh type
96.
Compare and contrast IgG and IgM antibodies

97.
Differentiate between the different anticoagulant-preservative chemicals 98. [Level 3/Final/ABO/723] Choose the appropriate method in resolving an ABO discrepancy 99.
Describe the formation of the H antigen and its relationship to ABO antigen expression 100. [Level 2/Final/AIHA/725] Give examples of medications that cause drug adsorption hemolytic anemia
Levels given in brackets at the beginning of the question objective indicate the level of difficulty for the actual question on this examination, NOT the level of difficulty for the stated objective. Levels of difficulty were developed using Bloom, et.al. Taxonomy of Educational Objectives. Also shown in the brackets are the Category of the question, the Topic of the question, and the number of the question in the database. Explanation of Categories in the Cognitive Domain: (with Outcome-Illustrating Verbs) Level 1: Recall Knowledge of terminology; specific facts; ways and means of dealing with specifics (conventions, trends and sequences, classifications and categories, criteria, methodology); universals and abstractions in a field (principles and generalizations, theories and structures). Knowledge is (here) defined as the remembering (recalling) of appropriate, previously learned information. * defines; describes; enumerates; identifies; labels; lists; matches; names; reads; records; reproduces; selects; states; views. Level 2: Comprehension Grasping (understanding) the meaning of informational materials. * classifies; cites; converts; describes; discusses; estimates; explains; generalizes; gives examples; makes sense out of; paraphrases; restates (in own words); summarizes; traces; understands. Level 3: Application The use of previously learned information in new and concrete situations to solve problems that have single or best answers. * acts; administers; articulates; assesses; charts; collects; computes; constructs; contributes; controls; determines; develops; discovers; establishes; extends; implements; includes; informs; instructs; operationalizes; participates; predicts; prepares; preserves; produces; projects; provides; relates; reports; shows; solves; teaches; transfers; uses; utilizes. Taxonomy of educational objectives : the classification of educational goals ; / by a committee of college and university examiners ; Benjamin S. Bloom, editor [and others] IMPRINT New York : D. McKay Co., Inc., c1956-1964 (1971-72 printing) DESCRIPT. 2 v. in 1 : ill. ; 22 cm. NOTE Vol.2 by D.R. Krathwohl and others.
Printed Wednesday, December 23, 2009 10:31:49 AM
Page 6 of 6

CLS 325 - 435 Final Exam Objectives

Încărcat de

Informații document

Descriere originală:

Titlu original

Drepturi de autor

Formate disponibile

Partajați acest document

Partajați sau inserați document

Opțiuni de partajare

Vi se pare util acest document?

Este necorespunzător acest conținut?

Drepturi de autor:

Formate disponibile

CLS 325 - 435 Final Exam Objectives

Încărcat de

Drepturi de autor:

Formate disponibile

Specific Examination Objectives

On this examination, the student will be expected to:

Identify naturally occurring antibodies produced by each ABO Blood Group

Explain how immunodeficiencies can affect blood bank testing

Interpret routine ABO typing results

See last page for explanation of question levels.

List causative agents for Cold Agglutinin Disease (CAD)

Differentiate between antigens enhanced and destroyed by proteolytic enzymes

See last page for explanation of question levels.

31. [Level 1/Final/Immunology/181] Define zeta potential

Describe the mechanisms of transfusion hemosiderosis

Discuss the composition and dosage of Rh immune globulin

See last page for explanation of question levels.

Describe the Kleihauer-Betke procedure and how to interpret results

Determine the type of HDN when presented with a clinical situation

Discuss how to remove cold reacting antibodies from serum

See last page for explanation of question levels.

71. [Level 2/Final/Transfusion Reactions/549] Describe the symptoms of circulatory overload

Differentiate between antigens enhanced and destroyed by proteolytic enzymes

Explain the purpose of washing cells prior to IAT testing

Correlate each lectin with its corresponding antigen specificity

See last page for explanation of question levels.

Discuss characteristics of the Bombay phenotype

Describe the biochemical changes that occur in stored blood

Compare and contrast IgG and IgM antibodies

Printed Wednesday, December 23, 2009 10:31:49 AM

See last page for explanation of question levels.

S-ar putea să vă placă și